DK175822B1 - Renset DNA-sekvens, som koder for en gæralkoholoxidase II-genregulatorregion - Google Patents

Renset DNA-sekvens, som koder for en gæralkoholoxidase II-genregulatorregion Download PDF

Info

Publication number
DK175822B1
DK175822B1 DK198903131A DK313189A DK175822B1 DK 175822 B1 DK175822 B1 DK 175822B1 DK 198903131 A DK198903131 A DK 198903131A DK 313189 A DK313189 A DK 313189A DK 175822 B1 DK175822 B1 DK 175822B1
Authority
DK
Denmark
Prior art keywords
aox2
dna sequence
gene
sequence
plasmid
Prior art date
Application number
DK198903131A
Other languages
Danish (da)
English (en)
Other versions
DK313189A (da
DK313189D0 (da
Inventor
James Michael Cregg
Original Assignee
Res Corp Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Corp Technologies Inc filed Critical Res Corp Technologies Inc
Publication of DK313189D0 publication Critical patent/DK313189D0/da
Publication of DK313189A publication Critical patent/DK313189A/da
Application granted granted Critical
Publication of DK175822B1 publication Critical patent/DK175822B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK198903131A 1988-06-24 1989-06-23 Renset DNA-sekvens, som koder for en gæralkoholoxidase II-genregulatorregion DK175822B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21100788 1988-06-24
US07/211,007 US5032516A (en) 1985-10-25 1988-06-24 Pichia pastoris alcohol oxidase II regulatory region

Publications (3)

Publication Number Publication Date
DK313189D0 DK313189D0 (da) 1989-06-23
DK313189A DK313189A (da) 1989-12-25
DK175822B1 true DK175822B1 (da) 2005-03-14

Family

ID=22785222

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198903131A DK175822B1 (da) 1988-06-24 1989-06-23 Renset DNA-sekvens, som koder for en gæralkoholoxidase II-genregulatorregion

Country Status (19)

Country Link
US (1) US5032516A (no)
EP (1) EP0347928A3 (no)
JP (1) JPH0773501B2 (no)
KR (1) KR960010590B1 (no)
CN (1) CN1039616A (no)
AU (1) AU615078B2 (no)
CA (1) CA1306211C (no)
DD (1) DD284047A5 (no)
DK (1) DK175822B1 (no)
FI (1) FI104497B (no)
HU (1) HUT51673A (no)
IE (1) IE67039B1 (no)
MX (1) MX16518A (no)
NO (1) NO301285B1 (no)
NZ (1) NZ229534A (no)
PH (1) PH27314A (no)
PT (1) PT90970A (no)
YU (1) YU128789A (no)
ZA (1) ZA894495B (no)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992013951A1 (en) * 1991-02-04 1992-08-20 The Salk Institute Biotechnology/Industrial Associates, Inc. Production of human serum albumin in methylotrophic yeast cells
CA2063890C (en) * 1991-03-27 2007-03-13 Masami Miura Mutant aox2 promoter, microorganism carrying same, method of preparation thereof and production of heterologous protein using such microorganism
JPH07106153B2 (ja) * 1991-03-27 1995-11-15 株式会社ミドリ十字 変異型aox2プロモーターを担持するプラスミド、形質転換体および異種蛋白質の製造方法
JPH0829102B2 (ja) * 1991-03-27 1996-03-27 株式会社ミドリ十字 変異型aox2プロモーター、当該プロモーターを担持する菌株、その取得方法およびその菌株を利用した異種蛋白質の製造方法
JP3505743B2 (ja) * 1993-07-27 2004-03-15 三菱ウェルファーマ株式会社 変異型aox2プロモーター、それを担持するベクター、形質転換体および異種蛋白質の製造方法
IT1270196B (it) * 1994-06-09 1997-04-29 Enichem Spa Procedimento catalitico per la produzione di ossime
US5945275A (en) * 1994-10-18 1999-08-31 Corvas International, Inc. Nematode-extracted anticoagulant protein
CA2202351A1 (en) * 1994-10-18 1996-04-25 George Phillip Vlasuk Nematode-extracted serine protease inhibitors and anticoagulant proteins
US5866542A (en) * 1994-10-18 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5863894A (en) * 1995-06-05 1999-01-26 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5866543A (en) * 1995-06-05 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
EP0788546B9 (en) 1994-10-18 2007-06-13 Dendreon Corporation Nematode-extracted serine protease inhibitors and anticoagulant proteins
US5872098A (en) * 1995-06-05 1999-02-16 Corvas International, Inc. Nematode-extracted anticoagulant protein
WO1997017450A2 (en) * 1995-11-09 1997-05-15 Zymogenetics, Inc. Compositions and methods for producing heterologous polypeptides in pichia methanolica
MX9605082A (es) 1996-10-24 1998-04-30 Univ Autonoma De Nuevo Leon Levaduras metilotroficas modificadas geneticamente para la produccion y secrecion de hormona de crecimiento humano.
DK1522590T3 (da) 2000-06-28 2009-12-21 Glycofi Inc Fremgangsmåde til fremstilling af modificerede glykoproteiner
US7449308B2 (en) * 2000-06-28 2008-11-11 Glycofi, Inc. Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
US7625756B2 (en) 2000-06-28 2009-12-01 GycoFi, Inc. Expression of class 2 mannosidase and class III mannosidase in lower eukaryotic cells
US8697394B2 (en) * 2000-06-28 2014-04-15 Glycofi, Inc. Production of modified glycoproteins having multiple antennary structures
US7863020B2 (en) * 2000-06-28 2011-01-04 Glycofi, Inc. Production of sialylated N-glycans in lower eukaryotes
US7598055B2 (en) * 2000-06-28 2009-10-06 Glycofi, Inc. N-acetylglucosaminyltransferase III expression in lower eukaryotes
MXPA03009059A (es) * 2001-04-05 2004-10-15 Univ Nebraska Secuencias de nucleotidos reguladoras de alcohol oxidasa 1 para expresion de genes heterologos en levadura.
US7118901B2 (en) * 2002-12-18 2006-10-10 Roche Diagnostics Operations, Inc. Recombinant bovine pancreatic desoxyribonuclease I with high specific activity
ATE387494T1 (de) * 2002-12-20 2008-03-15 Hoffmann La Roche Hitzelabile desoxyribonuklease i-varianten
US7332299B2 (en) 2003-02-20 2008-02-19 Glycofi, Inc. Endomannosidases in the modification of glycoproteins in eukaryotes
EP1460425A1 (en) * 2003-03-17 2004-09-22 Boehringer Mannheim Gmbh Deglycosylated enzymes for conjugates
ES2337684T3 (es) * 2003-12-05 2010-04-28 F. Hoffmann-La Roche Ag Carboxipeptidasa b recombinante y su purificacion.
MY146082A (en) * 2005-09-14 2012-06-29 Sanofi Aventis Deutschland Cleavage of precursors of insulins by a variant of trypsin
JP4216875B2 (ja) * 2006-09-29 2009-01-28 株式会社東芝 メタノール応答性プロモーター、プロモーターと外来遺伝子を発現可能な様式で連結した融合遺伝子、ベクター、形質転換体、およびタンパク質の生産方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0423890A3 (en) * 1984-07-27 1991-07-03 Unilever Nv Use of oxidoreductases in bleaching and/or detergent compositions and their preparation by microorganisms engineered by recombinant dna technology
US4855231A (en) * 1984-10-30 1989-08-08 Phillips Petroleum Company Regulatory region for heterologous gene expression in yeast
US4882279A (en) * 1985-10-25 1989-11-21 Phillips Petroleum Company Site selective genomic modification of yeast of the genus pichia
US4895800A (en) * 1985-11-26 1990-01-23 Phillips Petroleum Company Yeast production of hepatitis B surface antigen
IL82935A0 (en) * 1986-08-12 1987-12-20 Phillips Petroleum Co Secretion of heterologous proteins from yeast
NZ228948A (en) * 1988-05-13 1991-06-25 Phillips Petroleum Co Hbv particles containing s and pre-s 2 proteins and recombinant processes for their production in yeast cells

Also Published As

Publication number Publication date
PT90970A (pt) 1989-12-29
YU128789A (sh) 1992-07-20
MX16518A (es) 1993-10-01
CN1039616A (zh) 1990-02-14
NZ229534A (en) 1991-04-26
CA1306211C (en) 1992-08-11
EP0347928A2 (en) 1989-12-27
KR960010590B1 (ko) 1996-08-06
IE67039B1 (en) 1996-02-21
AU3700289A (en) 1990-01-04
NO892634D0 (no) 1989-06-23
FI893109A0 (fi) 1989-06-26
DK313189A (da) 1989-12-25
AU615078B2 (en) 1991-09-19
US5032516A (en) 1991-07-16
NO301285B1 (no) 1997-10-06
ZA894495B (en) 1990-03-28
IE892055L (en) 1989-12-24
NO892634L (no) 1989-12-27
KR910001049A (ko) 1991-01-30
JPH0773501B2 (ja) 1995-08-09
DD284047A5 (de) 1990-10-31
HUT51673A (en) 1990-05-28
DK313189D0 (da) 1989-06-23
FI893109A (fi) 1989-12-25
FI104497B (fi) 2000-02-15
EP0347928A3 (en) 1990-02-07
JPH0253489A (ja) 1990-02-22
PH27314A (en) 1993-05-28

Similar Documents

Publication Publication Date Title
DK175822B1 (da) Renset DNA-sekvens, som koder for en gæralkoholoxidase II-genregulatorregion
US4943529A (en) Kluyveromyces as a host strain
Kataoka et al. DNA sequence and characterization of the S. cerevisiae gene encoding adenylate cyclase
EP0510693B1 (en) Expression of human serum albumin in pichia pastoris
Hopper et al. The yeast RNA1 gene product necessary for RNA processing is located in the cytosol and apparently excluded from the nucleus.
Jarvis et al. Identification of a DNA segment that is necessary and sufficient for α-specific gene control in Saccharomyces cerevisiae: implications for regulation of α-specific and a-specific genes
McIver et al. Extension of host range of Rhizobium leguminosarum bv. trifolii caused by point mutations in nodD that result in alterations in regulatory function and recognition of inducer molecules
Haeuptle et al. A tripartite structure of the signals that determine protein insertion into the endoplasmic reticulum membrane.
NO178076B (no) Fremgangsmåte til å fremstille heterologe proteiner i Pichia pastoris ved bruk av ekspresjonsvektorer inneholdende sekvenser som induseres av metanol
NO854333L (no) Isolering av gener fra gjaerarter av slekten pichia.
NO172548B (no) Saccharomyces cerevisiae hybride vektorer og anvendelse av disse ved fremstilling av polypeptider
NO314151B1 (no) Pichia pastoris sur fosfatasegen
Aono et al. Mating pheromone‐induced expression of the mat1‐Pm gene of Schizosaccharomyces pombe: identification of signalling components and characterization of upstream controlling elements
Wilkins et al. A plasmid DNA primase active in discontinuous bacterial DNA replication
Holtel et al. Upstream binding sequences of the XyIR activator protein and integration host factor in the xylS gene promoter region of the Pseudomonas TOL plasmid
Yamashita et al. Microtubule‐associated coiled‐coil protein Ssm4 is involved in the meiotic development in fission yeast
DK172458B1 (da) Signalpeptid, DNA-sekvens, som koder for dette peptid, genstruktur indeholdende DNA-sekvensen, plasmid indeholdende DNA-sek
Tadayyon et al. TnblaM: a transposon for directly tagging bacterial genes encoding cell envelope and secreted proteins
Winzeler et al. Translation of the leaderless Caulobacter dnaX mRNA
EP0536192A1 (de) Neue promotorregion.
Kenri et al. Construction and characterization of an Escherichia coli mutant deficient in the metY gene encoding tRNAf2Met: either tRNAf1Met or tRNAf2Met is required for cell growth
JP2752092B2 (ja) Deoプロモーターを有する発現プラスミド及び該プラスミドを含む細菌宿主
US5786212A (en) Multiple integrative vectors and Yarrowia lipolytica transformants
FI105825B (fi) Pichia pastoris -kantoja
NO315206B1 (no) Nye celler inneholdende alkoholoksidase II regulatorisk område

Legal Events

Date Code Title Description
PUP Patent expired