DK175649B1 - Pyridoncarboxylsyrederivat, fremgangsmåde til fremstilling deraf og et middel indeholdende et pyridoncarboxylsyrederivat samt anvendelse af et sådant pyridoncarboxylsyrederivat til fremstilling af et terapeutisk middel - Google Patents

Pyridoncarboxylsyrederivat, fremgangsmåde til fremstilling deraf og et middel indeholdende et pyridoncarboxylsyrederivat samt anvendelse af et sådant pyridoncarboxylsyrederivat til fremstilling af et terapeutisk middel Download PDF

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Publication number
DK175649B1
DK175649B1 DK198901925A DK192589A DK175649B1 DK 175649 B1 DK175649 B1 DK 175649B1 DK 198901925 A DK198901925 A DK 198901925A DK 192589 A DK192589 A DK 192589A DK 175649 B1 DK175649 B1 DK 175649B1
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Prior art keywords
group
lower alkyl
dihydro
oxo
optionally protected
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Application number
DK198901925A
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Danish (da)
English (en)
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DK192589D0 (da
DK192589A (da
Inventor
Hirokazu Narita
Yozo Todo
Jun Nitta
Hiroyasu Takagi
Fumihiko Iino
Mikako Miyajima
Yoshikazu Fukuoka
Isamu Saikawa
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Toyama Chemical Co Ltd
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Publication date
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Publication of DK192589D0 publication Critical patent/DK192589D0/da
Publication of DK192589A publication Critical patent/DK192589A/da
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Publication of DK175649B1 publication Critical patent/DK175649B1/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06Peri-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06Peri-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
DK198901925A 1988-04-23 1989-04-20 Pyridoncarboxylsyrederivat, fremgangsmåde til fremstilling deraf og et middel indeholdende et pyridoncarboxylsyrederivat samt anvendelse af et sådant pyridoncarboxylsyrederivat til fremstilling af et terapeutisk middel DK175649B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP10062888 1988-04-23
JP10062888 1988-04-23
JP1075873A JPH0228178A (ja) 1988-04-23 1989-03-28 新規なピリドンカルボン酸誘導体およびその塩並びにそれらの製造法
JP7587389 1989-03-28

Publications (3)

Publication Number Publication Date
DK192589D0 DK192589D0 (da) 1989-04-20
DK192589A DK192589A (da) 1989-10-24
DK175649B1 true DK175649B1 (da) 2005-01-03

Family

ID=26417038

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198901925A DK175649B1 (da) 1988-04-23 1989-04-20 Pyridoncarboxylsyrederivat, fremgangsmåde til fremstilling deraf og et middel indeholdende et pyridoncarboxylsyrederivat samt anvendelse af et sådant pyridoncarboxylsyrederivat til fremstilling af et terapeutisk middel

Country Status (21)

Country Link
US (1) US4990508A (fr)
JP (1) JPH0228178A (fr)
KR (1) KR910005833B1 (fr)
AT (1) AT398422B (fr)
AU (1) AU601324B2 (fr)
BE (1) BE1003252A4 (fr)
CA (1) CA1340493C (fr)
CH (1) CH680793A5 (fr)
DE (1) DE3913245C2 (fr)
DK (1) DK175649B1 (fr)
ES (1) ES2016012A6 (fr)
FI (1) FI91529C (fr)
FR (1) FR2630441B1 (fr)
GB (1) GB2217710B (fr)
HU (2) HU205759B (fr)
IL (1) IL89931A (fr)
IT (1) IT1231760B (fr)
NL (1) NL192832C (fr)
NO (1) NO171214C (fr)
NZ (1) NZ228847A (fr)
SE (1) SE504625C2 (fr)

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EP0366189A3 (fr) * 1988-10-24 1992-01-02 Norwich Eaton Pharmaceuticals, Inc. Lactames-quinolones antimicrobiennes
EP0449445A3 (en) * 1990-03-27 1993-08-25 Pfizer Inc. Preparation of beta-ketoesters useful in preparing quinolone antibiotics
IT1248011B (it) * 1991-06-07 1995-01-05 Mediolanum Farmaceutici Spa Procedimento per la preparazione dell'acido 9-fluoro-10- (4-metil-1-piperazinil)-7-oxo-2,3-diidro-7h-pirido (1,2,3-de) (1,4)benzotiadin-6-carbossilico cloridrato.
EG20543A (en) * 1992-10-30 1999-07-31 Procter & Gamble Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones
TW252107B (fr) * 1993-08-27 1995-07-21 Hokuriku Pharmacetical Co Ltd
IT1270836B (it) * 1993-10-27 1997-05-13 Archimica Spa Procedimento per la preparazione di rufloxacina e suoi sali
IT1270834B (it) * 1993-10-27 1997-05-13 Archimica Spa Disolfuro chinolico
USH1480H (en) * 1993-12-09 1995-09-05 The Procter & Gamble Company Methods of using dyphylline for the promotion of hair growth
CA2367373C (fr) 1999-03-17 2011-09-20 Daiichi Pharmaceutical Co., Ltd. Compositions medicamenteuses
EA008889B1 (ru) 2002-03-21 2007-08-31 Басф Акциенгезельшафт Фунгицидные триазолопиримидины, способ их получения и их применение для борьбы с фитопатогенными грибами, а также содержащие их средства
CN1332962C (zh) * 2005-07-12 2007-08-22 武汉人福药业有限责任公司 一种合成甲磺酸帕珠沙星中间体的方法
KR101419554B1 (ko) * 2006-03-13 2014-07-17 교린 세이야꾸 가부시키 가이샤 Gsk­3 억제제로서 아미노퀴놀론
JP5426552B2 (ja) * 2007-09-11 2014-02-26 杏林製薬株式会社 Gsk−3阻害剤としてのシアノアミノキノロン及びテトラゾロアミノキノロン
US8476261B2 (en) 2007-09-12 2013-07-02 Kyorin Pharmaceutical Co., Ltd. Spirocyclic aminoquinolones as GSK-3 inhibitors
EP2406266B1 (fr) * 2009-03-11 2013-12-25 Kyorin Pharmaceutical Co., Ltd. 7-cycloalkylaminoquinolones comme inhibiteurs de la gsk-3
CN101928290B (zh) * 2009-11-27 2011-11-09 浙江司太立制药股份有限公司 一种甲磺酸帕珠沙星的纯化方法
CN102295652A (zh) * 2011-06-27 2011-12-28 辽宁海神联盛制药有限公司 一种甲磺酸帕珠沙星合成工艺的改进方法
CN102850375A (zh) * 2012-03-06 2013-01-02 江西师范大学 一类多取代吡啶并[4, 3-d]噁嗪化合物及制备方法
CN103772412B (zh) * 2012-10-23 2016-03-16 浙江海森药业有限公司 一种帕珠沙星中间体的制备方法
CN105622632B (zh) * 2014-10-29 2018-06-29 浙江海森药业股份有限公司 一种喹诺酮类化合物及其制备方法

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US3883522A (en) * 1974-02-11 1975-05-13 Riker Laboratories Inc Substituted pyrido(1,2,3-de)-1,4-benzoxazines
DE3211984C2 (de) * 1981-05-21 1986-04-03 Dieter Dr. 7900 Ulm Benz Rotierende Zahnbürste
JPS591489A (ja) * 1982-06-29 1984-01-06 Dai Ichi Seiyaku Co Ltd ピリドベンゾオキサジン誘導体
DE3234529A1 (de) * 1982-09-17 1984-03-22 Bayer Ag, 5090 Leverkusen Substituierte benzoxazin-derivate
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DE3639465A1 (de) * 1986-11-18 1988-05-19 Hoechst Ag Optisch aktive gyrasehemmer, ihre herstellung und verwendung als antibiotika
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US5039682A (en) * 1988-06-21 1991-08-13 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor

Also Published As

Publication number Publication date
NZ228847A (en) 1990-04-26
GB2217710A (en) 1989-11-01
NL8901007A (nl) 1989-11-16
NO891650L (no) 1989-10-24
DE3913245C2 (de) 1999-07-15
FI891910A0 (fi) 1989-04-21
DK192589D0 (da) 1989-04-20
FI91529B (fi) 1994-03-31
FI91529C (fi) 1994-07-11
IT1231760B (it) 1991-12-21
ES2016012A6 (es) 1990-10-01
FR2630441B1 (fr) 1994-10-14
IL89931A (en) 1993-06-10
AT398422B (de) 1994-12-27
CA1340493C (fr) 1999-04-13
JPH0588714B2 (fr) 1993-12-24
BE1003252A4 (fr) 1992-02-11
AU601324B2 (en) 1990-09-06
SE504625C2 (sv) 1997-03-17
US4990508A (en) 1991-02-05
IT8947875A0 (it) 1989-04-21
ATA95989A (de) 1994-04-15
AU3266189A (en) 1989-10-26
HU211568A9 (en) 1995-12-28
DK192589A (da) 1989-10-24
NO171214C (no) 1993-02-10
GB2217710B (en) 1991-12-04
DE3913245A1 (de) 1989-11-02
HU205759B (en) 1992-06-29
FR2630441A1 (fr) 1989-10-27
NL192832B (nl) 1997-11-03
NL192832C (nl) 1998-03-04
FI891910A (fi) 1989-10-24
SE8901464L (sv) 1989-10-24
IL89931A0 (en) 1989-12-15
GB8908096D0 (en) 1989-05-24
HUT51621A (en) 1990-05-28
CH680793A5 (fr) 1992-11-13
KR900016222A (ko) 1990-11-12
SE8901464D0 (sv) 1989-04-21
NO171214B (no) 1992-11-02
KR910005833B1 (ko) 1991-08-05
NO891650D0 (no) 1989-04-21
JPH0228178A (ja) 1990-01-30

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