DK174929B1 - Fremgangsmåde til fremstilling af quinolincarboxylsyrer eller derivater deraf - Google Patents

Fremgangsmåde til fremstilling af quinolincarboxylsyrer eller derivater deraf Download PDF

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Publication number
DK174929B1
DK174929B1 DK198706331A DK633187A DK174929B1 DK 174929 B1 DK174929 B1 DK 174929B1 DK 198706331 A DK198706331 A DK 198706331A DK 633187 A DK633187 A DK 633187A DK 174929 B1 DK174929 B1 DK 174929B1
Authority
DK
Denmark
Prior art keywords
oxo
cyclopropyl
dihydro
fluoro
methyl
Prior art date
Application number
DK198706331A
Other languages
Danish (da)
English (en)
Other versions
DK633187D0 (da
DK633187A (da
Inventor
Michael Preiss
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK633187D0 publication Critical patent/DK633187D0/da
Publication of DK633187A publication Critical patent/DK633187A/da
Application granted granted Critical
Publication of DK174929B1 publication Critical patent/DK174929B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK198706331A 1986-12-03 1987-12-02 Fremgangsmåde til fremstilling af quinolincarboxylsyrer eller derivater deraf DK174929B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19863641312 DE3641312A1 (de) 1986-12-03 1986-12-03 Verfahren zur herstellung von chinolincarbonsaeuren
DE3641312 1986-12-03

Publications (3)

Publication Number Publication Date
DK633187D0 DK633187D0 (da) 1987-12-02
DK633187A DK633187A (da) 1988-06-04
DK174929B1 true DK174929B1 (da) 2004-03-01

Family

ID=6315377

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198706331A DK174929B1 (da) 1986-12-03 1987-12-02 Fremgangsmåde til fremstilling af quinolincarboxylsyrer eller derivater deraf

Country Status (25)

Country Link
EP (1) EP0274033B1 (ja)
JP (1) JPS63145268A (ja)
KR (1) KR970005191B1 (ja)
CN (1) CN87107230A (ja)
AT (1) ATE73446T1 (ja)
AU (1) AU593961B2 (ja)
CS (1) CS270577B2 (ja)
DD (1) DD270904A5 (ja)
DE (2) DE3641312A1 (ja)
DK (1) DK174929B1 (ja)
ES (1) ES2038156T3 (ja)
FI (1) FI875289A (ja)
GR (1) GR3004301T3 (ja)
HU (1) HU199823B (ja)
IE (1) IE64261B1 (ja)
IL (1) IL84627A (ja)
NO (1) NO174199C (ja)
NZ (1) NZ222736A (ja)
PH (1) PH24489A (ja)
PL (1) PL158614B1 (ja)
PT (1) PT86252B (ja)
SU (1) SU1482526A3 (ja)
UA (1) UA8017A1 (ja)
YU (1) YU45049B (ja)
ZA (1) ZA879040B (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN166416B (ja) * 1985-09-18 1990-05-05 Pfizer
EP0470252A4 (en) * 1989-04-28 1992-12-02 Daiichi Pharmaceutical Co., Ltd. Anti-hiv drug
US5385913A (en) * 1989-10-06 1995-01-31 Pfizer Inc. 1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents
WO1991004972A1 (en) * 1989-10-06 1991-04-18 Pfizer Inc. 1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents
JP2613139B2 (ja) * 1990-07-19 1997-05-21 エスエス製薬 株式会社 キノロンカルボン酸誘導体
ES2050613B1 (es) * 1992-10-16 1996-03-16 Iteve S A Nuevo procedimiento para la preparacion de derivados del acido 1-ciclopropil-3-quinolincarboxilico.
US6034100A (en) * 1993-03-10 2000-03-07 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting cytokine secretion
AU6421898A (en) * 1997-03-25 1998-10-20 Sankyo Company Limited Anti-fiv agent
KR100454750B1 (ko) * 2002-06-20 2004-11-03 삼성에스디아이 주식회사 유기 전계 발광 소자용 청색 발광 화합물 및 이를 사용한유기 전계 발광 소자
BRPI0413964B8 (pt) 2003-09-10 2021-05-25 Kyorin Seiyaku Kk ácido derivado do ácido carboxílico quinolona, sua composição e agente antibacterial
JP5322927B2 (ja) 2007-05-24 2013-10-23 杏林製薬株式会社 １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体
CN101671302B (zh) * 2008-12-30 2011-03-30 广东海康兽药有限公司 禽畜用抗菌药恩诺沙星的生产工艺
CN101899044B (zh) * 2010-08-16 2012-07-18 常州市勇毅生物药业有限公司 吉米沙星主环化合物的合成方法
CN113912540A (zh) * 2021-12-15 2022-01-11 山东国邦药业有限公司 一种1-环丙基-6,7-二氟-1,4-二氢-4-氧代-3-喹啉甲酸的合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5365887A (en) * 1976-11-22 1978-06-12 Kyorin Seiyaku Kk Substituted quinoline*arboxylate and process for preparing same
DE2656574A1 (de) * 1976-12-10 1978-06-15 Schering Ag Neue 1,6-naphthyridincarbonsaeurederivate und verfahren zu ihrer herstellung
JPS53141286A (en) * 1977-05-16 1978-12-08 Kyorin Seiyaku Kk Novel substituted quinolinecarboxylic acid
JPS5845426B2 (ja) * 1978-09-29 1983-10-08 杏林製薬株式会社 置換キノリンカルボン酸誘導体
DE3142854A1 (de) * 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3318145A1 (de) * 1983-05-18 1984-11-22 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
AU553415B2 (en) * 1983-09-19 1986-07-17 Abbott Japan Co., Ltd. 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids
IL74244A (en) * 1984-02-17 1988-06-30 Warner Lambert Co Quinoline derivatives,their preparation and pharmaceutical compositions containing them
DE3420743A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-dihalogen-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
JPS61205258A (ja) * 1985-03-08 1986-09-11 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体及びその製造方法

Also Published As

Publication number Publication date
JPS63145268A (ja) 1988-06-17
PH24489A (en) 1990-07-18
KR880007472A (ko) 1988-08-27
UA8017A1 (uk) 1995-12-26
NO174199B (no) 1993-12-20
FI875289A0 (fi) 1987-12-01
ATE73446T1 (de) 1992-03-15
DK633187D0 (da) 1987-12-02
DE3777370D1 (de) 1992-04-16
DK633187A (da) 1988-06-04
CN87107230A (zh) 1988-07-06
NZ222736A (en) 1990-08-28
PT86252B (pt) 1990-11-07
DD270904A5 (de) 1989-08-16
IE873279L (en) 1988-06-03
NO874788D0 (no) 1987-11-17
PL269185A1 (en) 1989-01-05
IL84627A (en) 1992-01-15
CS868887A2 (en) 1989-11-14
NO174199C (no) 1994-04-06
PL158614B1 (pl) 1992-09-30
ZA879040B (en) 1988-05-26
IE64261B1 (en) 1995-07-26
EP0274033B1 (de) 1992-03-11
NO874788L (no) 1988-06-06
YU45049B (en) 1991-06-30
SU1482526A3 (ru) 1989-05-23
AU8217787A (en) 1988-06-09
EP0274033A1 (de) 1988-07-13
ES2038156T3 (es) 1993-07-16
CS270577B2 (en) 1990-07-12
HU199823B (en) 1990-03-28
HUT45521A (en) 1988-07-28
KR970005191B1 (ko) 1997-04-14
YU215687A (en) 1988-10-31
IL84627A0 (en) 1988-04-29
FI875289A (fi) 1988-06-04
PT86252A (en) 1988-01-01
DE3641312A1 (de) 1988-06-09
AU593961B2 (en) 1990-02-22
GR3004301T3 (ja) 1993-03-31

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