ES2038156T3 - Procedimiento para la obtencion de acidos quinolincarboxilicos. - Google Patents

Procedimiento para la obtencion de acidos quinolincarboxilicos.

Info

Publication number
ES2038156T3
ES2038156T3 ES198787117130T ES87117130T ES2038156T3 ES 2038156 T3 ES2038156 T3 ES 2038156T3 ES 198787117130 T ES198787117130 T ES 198787117130T ES 87117130 T ES87117130 T ES 87117130T ES 2038156 T3 ES2038156 T3 ES 2038156T3
Authority
ES
Spain
Prior art keywords
acids
quinolincarboxilic
procedure
obtaining
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787117130T
Other languages
English (en)
Inventor
Michael Dr. Preiss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2038156T3 publication Critical patent/ES2038156T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

EL INVENTO SE TRATA DE UN PROCEDIMIENTO PARA LA ELABORACION DE ACIDOS QUINDENCARBOXILICOS -H DE LA FORMULA I. DONDE R1, R2 Y R3, X Y A TIENEN UN SIGNIFICADO DADO EN LA DESCRIPCION QUE SE APLICAN COMO TALES O EN LA FORMA DE SU ESTER, SAL, PRODUG, ETC, COMO MEDIO ANTIBACTERIANO EN LA MEDICINA HUMANA, ANIMAL, ASI COMO LOS MEDIOS ESTIMULANDO LA DEFENSA INMUNE.
ES198787117130T 1986-12-03 1987-11-20 Procedimiento para la obtencion de acidos quinolincarboxilicos. Expired - Lifetime ES2038156T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863641312 DE3641312A1 (de) 1986-12-03 1986-12-03 Verfahren zur herstellung von chinolincarbonsaeuren

Publications (1)

Publication Number Publication Date
ES2038156T3 true ES2038156T3 (es) 1993-07-16

Family

ID=6315377

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787117130T Expired - Lifetime ES2038156T3 (es) 1986-12-03 1987-11-20 Procedimiento para la obtencion de acidos quinolincarboxilicos.

Country Status (25)

Country Link
EP (1) EP0274033B1 (es)
JP (1) JPS63145268A (es)
KR (1) KR970005191B1 (es)
CN (1) CN87107230A (es)
AT (1) ATE73446T1 (es)
AU (1) AU593961B2 (es)
CS (1) CS270577B2 (es)
DD (1) DD270904A5 (es)
DE (2) DE3641312A1 (es)
DK (1) DK174929B1 (es)
ES (1) ES2038156T3 (es)
FI (1) FI875289A (es)
GR (1) GR3004301T3 (es)
HU (1) HU199823B (es)
IE (1) IE64261B1 (es)
IL (1) IL84627A (es)
NO (1) NO174199C (es)
NZ (1) NZ222736A (es)
PH (1) PH24489A (es)
PL (1) PL158614B1 (es)
PT (1) PT86252B (es)
SU (1) SU1482526A3 (es)
UA (1) UA8017A1 (es)
YU (1) YU45049B (es)
ZA (1) ZA879040B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN166416B (es) * 1985-09-18 1990-05-05 Pfizer
EP0470252A4 (en) * 1989-04-28 1992-12-02 Daiichi Pharmaceutical Co., Ltd. Anti-hiv drug
US5385913A (en) * 1989-10-06 1995-01-31 Pfizer Inc. 1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents
WO1991004972A1 (en) * 1989-10-06 1991-04-18 Pfizer Inc. 1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents
JP2613139B2 (ja) * 1990-07-19 1997-05-21 エスエス製薬 株式会社 キノロンカルボン酸誘導体
ES2050613B1 (es) * 1992-10-16 1996-03-16 Iteve S A Nuevo procedimiento para la preparacion de derivados del acido 1-ciclopropil-3-quinolincarboxilico.
US6034100A (en) * 1993-03-10 2000-03-07 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting cytokine secretion
AU6421898A (en) * 1997-03-25 1998-10-20 Sankyo Company Limited Anti-fiv agent
KR100454750B1 (ko) * 2002-06-20 2004-11-03 삼성에스디아이 주식회사 유기 전계 발광 소자용 청색 발광 화합물 및 이를 사용한유기 전계 발광 소자
BRPI0413964B8 (pt) 2003-09-10 2021-05-25 Kyorin Seiyaku Kk ácido derivado do ácido carboxílico quinolona, sua composição e agente antibacterial
JP5322927B2 (ja) 2007-05-24 2013-10-23 杏林製薬株式会社 １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体
CN101671302B (zh) * 2008-12-30 2011-03-30 广东海康兽药有限公司 禽畜用抗菌药恩诺沙星的生产工艺
CN101899044B (zh) * 2010-08-16 2012-07-18 常州市勇毅生物药业有限公司 吉米沙星主环化合物的合成方法
CN113912540A (zh) * 2021-12-15 2022-01-11 山东国邦药业有限公司 一种1-环丙基-6,7-二氟-1,4-二氢-4-氧代-3-喹啉甲酸的合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5365887A (en) * 1976-11-22 1978-06-12 Kyorin Seiyaku Kk Substituted quinoline*arboxylate and process for preparing same
DE2656574A1 (de) * 1976-12-10 1978-06-15 Schering Ag Neue 1,6-naphthyridincarbonsaeurederivate und verfahren zu ihrer herstellung
JPS53141286A (en) * 1977-05-16 1978-12-08 Kyorin Seiyaku Kk Novel substituted quinolinecarboxylic acid
JPS5845426B2 (ja) * 1978-09-29 1983-10-08 杏林製薬株式会社 置換キノリンカルボン酸誘導体
DE3142854A1 (de) * 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3318145A1 (de) * 1983-05-18 1984-11-22 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
AU553415B2 (en) * 1983-09-19 1986-07-17 Abbott Japan Co., Ltd. 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids
IL74244A (en) * 1984-02-17 1988-06-30 Warner Lambert Co Quinoline derivatives,their preparation and pharmaceutical compositions containing them
DE3420743A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-dihalogen-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
JPS61205258A (ja) * 1985-03-08 1986-09-11 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体及びその製造方法

Also Published As

Publication number Publication date
JPS63145268A (ja) 1988-06-17
PH24489A (en) 1990-07-18
KR880007472A (ko) 1988-08-27
UA8017A1 (uk) 1995-12-26
NO174199B (no) 1993-12-20
FI875289A0 (fi) 1987-12-01
ATE73446T1 (de) 1992-03-15
DK633187D0 (da) 1987-12-02
DK174929B1 (da) 2004-03-01
DE3777370D1 (de) 1992-04-16
DK633187A (da) 1988-06-04
CN87107230A (zh) 1988-07-06
NZ222736A (en) 1990-08-28
PT86252B (pt) 1990-11-07
DD270904A5 (de) 1989-08-16
IE873279L (en) 1988-06-03
NO874788D0 (no) 1987-11-17
PL269185A1 (en) 1989-01-05
IL84627A (en) 1992-01-15
CS868887A2 (en) 1989-11-14
NO174199C (no) 1994-04-06
PL158614B1 (pl) 1992-09-30
ZA879040B (en) 1988-05-26
IE64261B1 (en) 1995-07-26
EP0274033B1 (de) 1992-03-11
NO874788L (no) 1988-06-06
YU45049B (en) 1991-06-30
SU1482526A3 (ru) 1989-05-23
AU8217787A (en) 1988-06-09
EP0274033A1 (de) 1988-07-13
CS270577B2 (en) 1990-07-12
HU199823B (en) 1990-03-28
HUT45521A (en) 1988-07-28
KR970005191B1 (ko) 1997-04-14
YU215687A (en) 1988-10-31
IL84627A0 (en) 1988-04-29
FI875289A (fi) 1988-06-04
PT86252A (en) 1988-01-01
DE3641312A1 (de) 1988-06-09
AU593961B2 (en) 1990-02-22
GR3004301T3 (es) 1993-03-31

Similar Documents

Publication Publication Date Title
ES2038156T3 (es) Procedimiento para la obtencion de acidos quinolincarboxilicos.
FI941245A (fi) Menetelmä 2'-deoksiguanosiinin asyylijohdannaisten valmistamiseksi
NO942468D0 (no) Fremgangsmåte for fremstilling av 2-alkyl-3,4,6-trifluorbenzoesyre
KR0148213B1 (en) Phenyla lkan(en)oic acid and pharmaceutical composition comprising the same
MA19764A1 (fr) Procede de preparation de derives de l'acide salycilique
ES2039267T3 (es) Dihidropiridinamidas, procedimiento para su preparacion y su empleo en medicamentos.
ES2082882T3 (es) Procedimiento para la fabricacion de derivados de acidos-3-amino-2-(het)aroil-acrilicos.
ES499363A0 (es) Procedimiento para la obtencion de derivados de fenilpipera-cina de 1,3,4-oxadiazolilfenoles
DE3882381D1 (es)
PT87563A (pt) Process for the preparation of vinylcephalosporins useful as medicaments
IE802102L (en) Pyrrolecarboxylic acid esters
HK1006713A1 (en) Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters pyridine-n-oxides thereof a process for their preparation and their use as medicaments
HUT44802A (en) Process for producing pseudo-oligosaccharides and pharmaceutical compositions containing them
MX9300136A (es) Alfa-aril-alfa-hidroxi-beta-imidazolinil-propionamidas, procedimiento para su obtencion y medicamentos que las contienen.
ES508757A0 (es) "procedimiento para la preparacion de acidos antranilicos sustituidos con radicales basicos"
ES528323A0 (es) Procedimiento para la preparacion de derivados de 6 -metilprednisolona
ES473070A1 (es) Procedimiento para la obtencion de 2,3,4,7,8.9-octahidropi- razinopirimidinonas substituidas
IT7945204A0 (it) Composizione farmaceutica per la terapia delle sterilita' maschile

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 274033

Country of ref document: ES