DK173262B1 - Syntetisk polypeptid og dets anvendelse til diagnosticering af Epstein-Barr-virus, syntetisk polypeptidoligomer og syntetis - Google Patents

Syntetisk polypeptid og dets anvendelse til diagnosticering af Epstein-Barr-virus, syntetisk polypeptidoligomer og syntetis Download PDF

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Publication number
DK173262B1
DK173262B1 DK198706388A DK638887A DK173262B1 DK 173262 B1 DK173262 B1 DK 173262B1 DK 198706388 A DK198706388 A DK 198706388A DK 638887 A DK638887 A DK 638887A DK 173262 B1 DK173262 B1 DK 173262B1
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Prior art keywords
polypeptide
amino acid
antibodies
synthetic polypeptide
immunoreactant
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DK198706388A
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Danish (da)
English (en)
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DK638887A (da
DK638887D0 (da
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Robert I Fox
Richard Houghton
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Scripps Clinic Res
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/085Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16211Lymphocryptovirus, e.g. human herpesvirus 4, Epstein-Barr Virus
    • C12N2710/16222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polyamides (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK198706388A 1986-12-05 1987-12-04 Syntetisk polypeptid og dets anvendelse til diagnosticering af Epstein-Barr-virus, syntetisk polypeptidoligomer og syntetis DK173262B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93864386 1986-12-05
US06/938,643 US4879213A (en) 1986-12-05 1986-12-05 Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse

Publications (3)

Publication Number Publication Date
DK638887D0 DK638887D0 (da) 1987-12-04
DK638887A DK638887A (da) 1988-06-06
DK173262B1 true DK173262B1 (da) 2000-05-29

Family

ID=25471727

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198706388A DK173262B1 (da) 1986-12-05 1987-12-04 Syntetisk polypeptid og dets anvendelse til diagnosticering af Epstein-Barr-virus, syntetisk polypeptidoligomer og syntetis

Country Status (13)

Country Link
US (1) US4879213A (ja)
EP (1) EP0280813B1 (ja)
JP (2) JP2624973B2 (ja)
AT (1) ATE107316T1 (ja)
AU (1) AU610099B2 (ja)
CA (1) CA1315481C (ja)
DE (1) DE3750088T2 (ja)
DK (1) DK173262B1 (ja)
ES (1) ES2054692T3 (ja)
IE (1) IE63368B1 (ja)
IL (1) IL84690A (ja)
NZ (1) NZ222794A (ja)
ZA (1) ZA879025B (ja)

Families Citing this family (164)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7351412B1 (en) * 1983-12-05 2008-04-01 Institut Pasteur Cloned DNA sequences related to the genomic RNA of lymphadenopathy-associated-virus (LAV) and proteins encoded by said LAV genomic RNA
US5116725A (en) * 1984-08-08 1992-05-26 Scripps Clinic And Research Foundation Assay for Epstein-Barr virus infection with solid phase bound synthetic polypeptides
US5256768A (en) * 1985-12-13 1993-10-26 The Johns Hopkins University Expression of antigenic Epstein-Barr virus polypeptides in bacteria and their use in diagnostics
US6172186B1 (en) * 1986-03-26 2001-01-09 Pharmacia & Upjohn Company Pseudorabies virus protein
US6255078B1 (en) * 1986-03-26 2001-07-03 Pharmacia & Upjohn Company Pseudorabies virus protein cross reference to related applications
DE3706233A1 (de) * 1987-02-26 1988-09-08 Behringwerke Ag Immunogene fusionsproteine, die epstein-barr-virusproteine enthalten
NZ225295A (en) * 1987-07-07 1991-07-26 Biotech Australia Pty Ltd Nematode antigen, its production and vaccines containing it
US5948644A (en) * 1988-09-26 1999-09-07 Biotechnology Australia Pty Ltd. Polynucleotides encoding excretory/secretory proteins of parasitic nematodes, host cells transformed therewith
US5079172A (en) * 1988-11-04 1992-01-07 Board Of Trustees Operating Michigan State University Method for detecting the presence of antibodies using gold-labeled antibodies and test kit
US6572862B1 (en) * 1989-11-08 2003-06-03 Baylor College Of Medicine Methods and reagents to detect and characterize Norwalk and related viruses
US5374517A (en) * 1989-11-24 1994-12-20 Council Of The Queensland Institute Of Medical Research IM peptides
AU640430B2 (en) * 1989-11-24 1993-08-26 Council Of The Queensland Institute Of Medical Research, The Im peptides
US5106726A (en) * 1990-02-16 1992-04-21 United Biomedical, Inc. Synthetic peptides specific for the detection of antibodies to HCV
JP2596466B2 (ja) * 1990-03-03 1997-04-02 アサヒビール株式会社 ダニの主要アレルゲンの還伝情報を有するdnaおよび該アレルゲンの製造方法
US6197548B1 (en) 1990-04-02 2001-03-06 Medeva Pharma Limited Transformed Pichia expressing the pertactin antigen
US5798106A (en) * 1990-06-06 1998-08-25 University Of Nijmegan Protein
GB9014950D0 (en) * 1990-07-06 1990-08-29 Univ Glasgow Ehv-4 glycoprotein vaccine
US5674735A (en) * 1990-07-06 1997-10-07 University Court Of The University Of Glasgow DNA encoding the EHV-4 gH or gC glycoprotein
EP0540645A4 (en) * 1990-07-24 1993-12-29 The Uab Research Foundation Methods of use of bovine respiratory syncytial virus recombinant dna, proteins vaccines, antibodies, and transformed cells
US6730305B1 (en) 2000-05-08 2004-05-04 The Uab Research Foundation Nucleotide sequences encoding bovine respiratory syncytial virus immunogenic proteins
GB9016315D0 (en) * 1990-07-25 1990-09-12 Burnie James P Medicaments
US5736362A (en) * 1990-10-26 1998-04-07 The University Of Melbourne Ryegrass pollen allergen
US5972337A (en) * 1990-11-01 1999-10-26 Cancer Research Fund Of Contra Costa 46 kilodalton human milk fat globule (HMFG) antigen, fragments and fusion protein
US5200344A (en) * 1990-11-13 1993-04-06 Blaser Martin J Diagnostic testing for campylobacter jejuni or campylobacter coli infections using novel antigens
JP3015969B2 (ja) * 1990-11-30 2000-03-06 ダイナボット株式会社 扁平上皮癌関連抗原蛋白質及び該蛋白質をコードするdna
GB9027728D0 (en) * 1990-12-20 1991-02-13 Smithkline Beecham Biolog Novel protein
US5741493A (en) * 1991-01-24 1998-04-21 Pasteur Merieux Serums Et Vaccins Vaccine composition against influenza, with synergic effects, containing influenza virus core as an additive
US5525508A (en) * 1991-02-06 1996-06-11 Biotech Australia Pty Limited Haemonchus contortus vaccine
CA2079871A1 (en) * 1991-02-06 1992-08-07 Phillip John Sharp Vaccine
US6673916B1 (en) 1991-02-12 2004-01-06 Colorado State University Research Foundation Compositions of parasitic helminth PLA2 nucleic acid molecules and uses thereof
US6099843A (en) * 1991-02-12 2000-08-08 Heska Corporation Parasitic helminth PLA2 proteins
US6419923B1 (en) * 1991-02-12 2002-07-16 Heska Corporation Filariid nematode cysteine protease proteins, and uses thereof
EP0510691B1 (en) * 1991-04-26 2004-11-03 Osaka Bioscience Institute DNA coding for human cell surface antigen
ZA924203B (en) * 1991-06-18 1993-03-31 Akzo Nv Coccidiosis poultry vaccine
US5670362A (en) * 1991-06-18 1997-09-23 Akzo Nobel N.V. DNA encoding an Eimeria 100kD antigen
US6146870A (en) * 1991-12-13 2000-11-14 Heska Corporation Flea protease proteins
GB9200117D0 (en) * 1992-01-06 1992-02-26 Connaught Lab Production of recombinant chimeric proteins for vaccine use
US7141244B1 (en) * 1992-03-02 2006-11-28 Chiron Srl Helicobacter pylori proteins useful for vaccines and diagnostics
GB9209993D0 (en) * 1992-05-08 1992-06-24 Munn Edward A Vaccines
US5736141A (en) * 1992-06-05 1998-04-07 Dalhousie University Method to prevent fertilization in mammals by administering a single dose of zona pellucida derived antigens, liposome and Freund's adjuvant
USRE37224E1 (en) * 1992-06-05 2001-06-12 Dalhousie University Method to prevent fertilization in mammals by administering a single dose of zona pellucida derived antigens, liposome and adjuvant
US5980899A (en) * 1992-06-10 1999-11-09 The United States Of America As Represented By The Department Of Health And Human Services Identification of peptides that stimulate hepatitis C virus specific cytotoxic T cells
US7326535B2 (en) 1993-09-15 2008-02-05 Ortho Diagnostic Systems Inc. Immunoreactive peptides from Epstein-Barr virus
ATE428724T1 (de) * 1992-09-15 2009-05-15 Ortho Diagnostic Systems Inc Immunreaktive peptide des epstein-barrvirus
US7060283B1 (en) 1992-09-15 2006-06-13 Ortho Diagnostic Systems, Inc. Immunoreactive peptides from Epstein-Barr virus
US5962316A (en) 1992-10-16 1999-10-05 Cold Spring Harbor Laboratory Cell-cycle regulatory proteins, and uses related thereto
US6290962B1 (en) * 1992-11-03 2001-09-18 Oravax, Inc. Urease-based vaccine and treatment for helicobacter infection
US5972336A (en) * 1992-11-03 1999-10-26 Oravax Merieux Co. Urease-based vaccine against helicobacter infection
DK0680338T3 (da) * 1993-01-22 2003-07-21 Sloan Kettering Inst Cancer Gangliosid-KLH-konjugat-vacciner med QS-21
AU6142694A (en) * 1993-02-26 1994-09-14 Finnish National Public Health Institute, The Method and system for enhanced production of commercially important exoproteins in gram-positive bacteria
US6849427B1 (en) * 1993-03-12 2005-02-01 Immulogic Pharmaceutical Corp. Nucleic acids encoding a house dust mite allergen, Der p VII, and uses therefor
CA2116640A1 (en) * 1993-03-25 1994-09-26 Alexey Terskikh Carcinoembryonic antigen derivatives
US6632613B1 (en) * 1993-06-02 2003-10-14 University Of Utah Research Foundation Compositions and kits for fluorescence polarization assay of large molecules
GB9312324D0 (en) * 1993-06-15 1993-07-28 Pitman Moore Inc Vaccine
US5571711A (en) * 1993-06-17 1996-11-05 Ludwig Institute For Cancer Research Isolated nucleic acid molecules coding for BAGE tumor rejection antigen precursors
JPH09502604A (ja) * 1993-08-27 1997-03-18 エンテリック リサーチ ラボラトリーズ インコーポレイテッド Campylobacterjejuni抗原、並びにそれらの製造及び利用
EP0716697B1 (en) * 1993-09-03 2003-04-02 McGILL UNIVERSITY DIFFERENTIALLY EXPRESSED $i(LEISHMANIA) GENES AND PROTEINS
GB9322702D0 (en) * 1993-11-03 1993-12-22 Agricultural & Food Res Vaccines
US7691632B2 (en) * 1993-11-18 2010-04-06 Cold Spring Harbor Laboratory Kit for detecting the level of cyclin-dependent kinase inhibitor P16 gene expression
SE9400088D0 (sv) * 1994-01-14 1994-01-14 Kabi Pharmacia Ab Bacterial receptor structures
US6740734B1 (en) 1994-01-14 2004-05-25 Biovitrum Ab Bacterial receptor structures
AUPM368994A0 (en) * 1994-02-04 1994-02-24 Saramane Pty Ltd Malaria merozoite antigen subunit vaccine
WO1995021929A1 (en) * 1994-02-09 1995-08-17 Mogen International N.V. Antifungal proteins, dna coding therefor, and hosts incorporating same
WO1995021917A1 (en) 1994-02-14 1995-08-17 Amgen Inc. Mammalian cell cycle protein
US20030129204A1 (en) * 1994-03-25 2003-07-10 Moredun Scientific Limited Vaccines against helminthic parasites
US5693496A (en) * 1994-06-20 1997-12-02 Merck & Co., Inc. DNA encoding the mouse and human PH30 beta chain protein
WO1996001273A1 (en) * 1994-07-01 1996-01-18 Rican Limited Helicobacter pylori antigenic protein preparation and immunoassays
ZA958366B (en) * 1994-10-06 1996-04-24 Akzo Nobel Nv New toxoplasma gondii antigens
US8791237B2 (en) 1994-11-08 2014-07-29 The Trustees Of The University Of Pennsylvania Compositions and methods for treatment of non-hodgkins lymphoma
US6051237A (en) * 1994-11-08 2000-04-18 The Trustees Of The University Of Pennsylvania Specific immunotherapy of cancer using a live recombinant bacterial vaccine vector
US8114414B2 (en) * 1994-11-08 2012-02-14 The Trustees Of The University Of Pennsylvania Compositions and methods for treatment of cervical cancer
US8956621B2 (en) 1994-11-08 2015-02-17 The Trustees Of The University Of Pennsylvania Compositions and methods for treatment of cervical dysplasia
US5976543A (en) * 1994-12-04 1999-11-02 Yeda Research And Development Co., Ltd. 12-kDa protein derived from M. Tuberculosis useful for treatment of autoimmune diseases
FR2728904B1 (fr) * 1995-01-04 1997-03-14 Pasteur Institut Reactif peptidique permettant de detecter une infection primaire a virus d'epstein-barr par recherche des anticorps correspondants, et procede d'utilisation de ce reactif
US6287574B1 (en) * 1995-03-17 2001-09-11 Biochem Pharma Inc. Proteinase K resistant surface protein of neisseria meningitidis
US6506553B1 (en) * 1995-03-30 2003-01-14 Ortho Diagnostics Systems, Inc. Method for diagnosis of Epstein-Barr virus associated disease
PT747481E (pt) * 1995-06-06 2002-05-31 Organon Teknika Bv Peptidos do virus de epstein-barr e anticorpos contra estes peptidos
US6251405B1 (en) * 1995-06-07 2001-06-26 Connaught Laboratories, Inc. Immunological combination compositions and methods
ZA964896B (en) 1995-06-07 1997-01-08 Connaught Lab Expression of lipoproteins
US5863543A (en) * 1996-06-05 1999-01-26 University Of Saskatchewan Camp factor of streptococcus uberis
US6936259B2 (en) 1995-06-08 2005-08-30 University Of Saskatchewan CAMP factor of Streptococcus uberis
FR2736360B1 (fr) * 1995-07-04 1997-09-05 Pasteur Institut Clonage et caracterisation du gene fiba de h.pylori, production de souches aflagellees
US6338852B1 (en) 1995-09-01 2002-01-15 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6592877B1 (en) * 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6290969B1 (en) 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6458366B1 (en) * 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
KR19990063761A (ko) * 1995-09-26 1999-07-26 엘. 데이예를 카렌. 헤르페스 비루스에 속하는 rfhv/kshv 아과의 당단백질b
US6610506B1 (en) * 1995-12-01 2003-08-26 University Technologies International, Inc. Transferrin binding proteins of Pasteurella haemolytica and vaccines containing same
US6001600A (en) * 1996-12-20 1999-12-14 Smithkline Beecham Plc DNA encoding tests polypeptides
GB9526359D0 (en) * 1995-12-22 1996-02-21 Smithkline Beecham Plc Novel compounds
GB9526356D0 (en) * 1995-12-22 1996-02-21 Smithkline Beecham Plc Novel compounds
AU1463097A (en) * 1996-01-04 1997-08-01 Rican Limited Helicobacter pylori bacterioferritin
US5910568A (en) * 1996-01-11 1999-06-08 The Penn State Research Foundation Molecule involved in binding of sperm to egg surfaces and procedures for use of this molecule to enhance or decrease potential fertility
GB9600955D0 (en) * 1996-01-17 1996-03-20 Smithkline Beecham Plc Novel compounds
DE19601754A1 (de) * 1996-01-19 1997-07-24 Hoechst Ag Dictyocaulus viviparus Antigen zur Diagnose des Lungenwurmbefalls und zur Vakzinierung
US6087163A (en) 1997-02-06 2000-07-11 The Public Health Research Institute Of The City Of New York, Inc. Mycobacterium tuberculosis specific proteins and genes, mixtures of anitgens and uses thereof
US7341727B1 (en) * 1996-05-03 2008-03-11 Emergent Product Development Gaithersburg Inc. M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same
CN1198185A (zh) * 1996-08-01 1998-11-04 D·沃利斯 乳头瘤趾皮炎的检测、预防和治疗
US5952194A (en) * 1996-08-01 1999-09-14 Heska Corporation Flea nucleic acid sequences and uses thereof
US6284255B1 (en) * 1996-08-29 2001-09-04 Genesis Research & Development Corporation Limited Compounds and methods for treatment and diagnosis of mycobacterial infections
US6190659B1 (en) * 1996-09-17 2001-02-20 The Rockefeller University Bacterial plasmin binding protein and methods of use thereof
US5976542A (en) * 1996-09-23 1999-11-02 New England Medical Center Compositions and methods for treatment of streptococcus pneumoniae infection
US6451315B1 (en) 1996-10-01 2002-09-17 Corixa Corporation Compounds and methods for the diagnosis and treatment of B. microti infection
US20040023865A1 (en) * 1996-10-01 2004-02-05 Corixa Corporation Compounds and methods for the diagnosis and treatment of B. microti infection
US6183976B1 (en) 1996-10-01 2001-02-06 Corixa Corporation Compounds and methods for the diagnosis and treatment of B. microti infection
US6214971B1 (en) 1996-10-01 2001-04-10 Corixa Corporation Compounds and methods for the diagnosis and treatment of Babesia microti infection
US6569433B1 (en) 1996-10-01 2003-05-27 Corixa Corporation Compounds and methods for the diagnosis and treatment of B. microti infection
US6306396B1 (en) * 1996-10-01 2001-10-23 Corixa Corporation Compounds and methods for the diagnosis and treatment of B. microti infection
US6025338A (en) 1996-10-17 2000-02-15 University Of Florida Nucleic acid vaccines against rickettsial diseases and methods of use
US6593147B1 (en) 1996-10-17 2003-07-15 University Of Florida Research Foundation, Inc. Nucleic acid vaccines against rickettsial diseases and methods of use
US6653128B2 (en) 1996-10-17 2003-11-25 University Of Florida Nucleic acid vaccines against rickettsial diseases and methods of use
US6372887B1 (en) * 1996-11-07 2002-04-16 Heska Corporation Flea serine protease inhibitor proteins
US5869290A (en) * 1996-11-21 1999-02-09 Smithkline Beecham Corporation Cayae1 polynucleotides
US6403093B1 (en) * 1997-03-21 2002-06-11 Mayo Foundation For Medical Education And Research Methods to detect granulocytic ehrlichiosis
US6613881B1 (en) 1997-05-20 2003-09-02 Corixa Corporation Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
US6555653B2 (en) 1997-05-20 2003-04-29 Corixa Corporation Compounds for diagnosis of tuberculosis and methods for their use
AUPO784197A0 (en) 1997-07-10 1997-08-07 Csl Limited Treatment of nasopharyngeal carcinoma
US7588766B1 (en) * 2000-05-26 2009-09-15 Elan Pharma International Limited Treatment of amyloidogenic disease
US7964192B1 (en) 1997-12-02 2011-06-21 Janssen Alzheimer Immunotherapy Prevention and treatment of amyloidgenic disease
TWI239847B (en) 1997-12-02 2005-09-21 Elan Pharm Inc N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
US20080050367A1 (en) 1998-04-07 2008-02-28 Guriq Basi Humanized antibodies that recognize beta amyloid peptide
US7790856B2 (en) 1998-04-07 2010-09-07 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize beta amyloid peptide
US6761888B1 (en) 2000-05-26 2004-07-13 Neuralab Limited Passive immunization treatment of Alzheimer's disease
JP2002529705A (ja) * 1998-10-29 2002-09-10 コンネクス・ゲーエムベーハー 糞便中の耐酸性微生物を検出するための新規方法
US6465633B1 (en) 1998-12-24 2002-10-15 Corixa Corporation Compositions and methods of their use in the treatment, prevention and diagnosis of tuberculosis
MXPA01009256A (es) * 1999-03-12 2003-07-14 Aventis Pasteur Antigenos de chlamydia y fragmentos de acido desoxirribonucleico correspondientes y usos de los mismos.
US8143386B2 (en) * 1999-04-07 2012-03-27 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
US6602977B1 (en) 1999-04-19 2003-08-05 Biovitrum Ab Receptor structures
CA2386841A1 (en) * 1999-10-07 2001-04-12 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
AU2001241738A1 (en) * 2000-02-25 2001-09-03 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
CA2404164A1 (en) * 2000-03-29 2001-10-04 The Trustees Of The University Of Pennsylvania Compositions and methods for enhancing immunogenicity of antigens
ATE526994T1 (de) * 2000-06-20 2011-10-15 Corixa Corp Mtb32a antigen aus mycobakterium tuberculosis mit inaktivierter protease aktivität und fusionsproteine die das antigen enthalten
US6821739B2 (en) * 2000-10-13 2004-11-23 The Regents Of The University Of California Methods of diagnosing and treating Crohn's disease using Pseudomonas antigens
US7700751B2 (en) 2000-12-06 2010-04-20 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize β-amyloid peptide
US7700344B2 (en) * 2001-03-26 2010-04-20 The Trustees Of The University Of Pennsylvania Compositions and methods for enhancing the immunogenicity of antigens
US8771702B2 (en) * 2001-03-26 2014-07-08 The Trustees Of The University Of Pennsylvania Non-hemolytic LLO fusion proteins and methods of utilizing same
WO2003018054A1 (en) * 2001-08-31 2003-03-06 Chiron Srl. Helicobacter pylori vaccination
NO318426B1 (no) 2001-10-02 2005-04-18 Neurozym Biotech As Et materiale for a senke konsentrasjonen av patogene tarmpeptider
WO2003070187A2 (en) 2002-02-15 2003-08-28 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
MY139983A (en) 2002-03-12 2009-11-30 Janssen Alzheimer Immunotherap Humanized antibodies that recognize beta amyloid peptide
US7344718B2 (en) * 2003-01-31 2008-03-18 University Of North Dakota Yersinia species compositions
BRPI0407058A (pt) * 2003-02-01 2006-01-17 Neuralab Ltd Métodos de profilaxia e de tratamento de uma doença, composição farmacêutica, e, uso de um fragmento
TWI374893B (en) 2003-05-30 2012-10-21 Janssen Alzheimer Immunotherap Humanized antibodies that recognize beta amyloid peptide
CA2540896C (en) * 2003-10-02 2015-06-02 Chiron Srl Liquid vaccines for multiple meningococcal serogroups
TW200636066A (en) 2004-12-15 2006-10-16 Elan Pharm Inc Humanized antibodies that recognize beta amyloid peptide
WO2006066089A1 (en) 2004-12-15 2006-06-22 Neuralab Limited Humanized amyloid beta antibodies for use in improving cognition
GB0507632D0 (en) * 2005-04-15 2005-05-25 Secr Defence Vaccine
GB0519871D0 (en) * 2005-09-30 2005-11-09 Secr Defence Immunogenic agents
US8784810B2 (en) 2006-04-18 2014-07-22 Janssen Alzheimer Immunotherapy Treatment of amyloidogenic diseases
US8268326B2 (en) * 2006-08-15 2012-09-18 The Trustees Of The University Of Pennsylvania Compositions comprising HMW-MAA and fragments thereof, and methods of use thereof
EP2061800B1 (en) * 2006-08-15 2015-07-29 The Trustees of the University of Pennsylvania Compositions comprising hmw-maa and fragments thereof, and methods of use thereof
RU2487890C2 (ru) * 2007-04-16 2013-07-20 МинерваКС Апс Слитый белок, способный индуцировать защитный иммунитет против стрептококка группы в, и вакцина, содержащая такой белок
US8003097B2 (en) 2007-04-18 2011-08-23 Janssen Alzheimer Immunotherapy Treatment of cerebral amyloid angiopathy
JP5889529B2 (ja) 2007-07-27 2016-03-22 ヤンセン・サイエンシズ・アイルランド・ユーシー アミロイド原性疾患の処置
JO3076B1 (ar) 2007-10-17 2017-03-15 Janssen Alzheimer Immunotherap نظم العلاج المناعي المعتمد على حالة apoe
US8758765B2 (en) * 2008-07-29 2014-06-24 The University Of Chicago Compositions and methods related to Staphylococcal bacterium proteins
US9067981B1 (en) 2008-10-30 2015-06-30 Janssen Sciences Ireland Uc Hybrid amyloid-beta antibodies
GB0900455D0 (en) 2009-01-13 2009-02-11 Secr Defence Vaccine
EP2403935B1 (en) 2009-03-04 2017-05-10 The Trustees Of The University Of Pennsylvania Compositions comprising angiogenic factors and methods of use thereof
DK2248533T3 (da) * 2009-05-05 2014-02-10 Universitaetsklinikum Freiburg Polypeptid afledt af enterococcus samt dets anvendelse til vaccination
WO2012170356A1 (en) * 2011-06-04 2012-12-13 Rochester General Hospital Research Institute Compositions and methods related to p6 of haemophilus influenzae
WO2012178078A2 (en) 2011-06-22 2012-12-27 University Of North Dakota Use of yscf, truncated yscf and yscf homologs as adjuvants
WO2013113000A2 (en) 2012-01-26 2013-08-01 Luc Montagnier Detection of dna sequences as risk factors for hiv infection
WO2014025254A1 (en) 2012-08-10 2014-02-13 Stichting Vu-Vumc Ebv markers and systemic lupus erythematosus

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4707358A (en) * 1984-01-30 1987-11-17 The University Of Chicago Vaccine against Epstein-Barr Virus
US4654419A (en) * 1984-08-08 1987-03-31 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to epstein-barr virus nuclear antigen

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JPS63225398A (ja) 1988-09-20
EP0280813A2 (en) 1988-09-07
JP2682959B2 (ja) 1997-11-26
ZA879025B (en) 1988-05-27
IL84690A0 (en) 1988-05-31
JP2624973B2 (ja) 1997-06-25
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DE3750088D1 (de) 1994-07-21
EP0280813A3 (en) 1990-06-06
US4879213A (en) 1989-11-07
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IE63368B1 (en) 1995-04-19
CA1315481C (en) 1993-03-30
ES2054692T3 (es) 1994-08-16
DK638887D0 (da) 1987-12-04
ATE107316T1 (de) 1994-07-15
AU8207387A (en) 1988-06-09
IL84690A (en) 1992-11-15
JPH07233200A (ja) 1995-09-05
IE873303L (en) 1988-06-05
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