DK172921B1 - Naturligt, pulmonart, overfladeaktivt middel, fremgangsmåde til fremstilling heraf samt farmaceutiske midler indeholdende d - Google Patents

Naturligt, pulmonart, overfladeaktivt middel, fremgangsmåde til fremstilling heraf samt farmaceutiske midler indeholdende d Download PDF

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Publication number
DK172921B1
DK172921B1 DK198801900A DK190088A DK172921B1 DK 172921 B1 DK172921 B1 DK 172921B1 DK 198801900 A DK198801900 A DK 198801900A DK 190088 A DK190088 A DK 190088A DK 172921 B1 DK172921 B1 DK 172921B1
Authority
DK
Denmark
Prior art keywords
surfactant
pulmonary
fraction
pharmaceutical agents
phospholipid
Prior art date
Application number
DK198801900A
Other languages
Danish (da)
English (en)
Other versions
DK190088D0 (da
DK190088A (da
Inventor
Bengt Robertson
Tore Curstedt
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of DK190088D0 publication Critical patent/DK190088D0/da
Publication of DK190088A publication Critical patent/DK190088A/da
Application granted granted Critical
Publication of DK172921B1 publication Critical patent/DK172921B1/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/42—Respiratory system, e.g. lungs, bronchi or lung cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0082—Lung surfactant, artificial mucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Physiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
DK198801900A 1987-04-08 1988-04-07 Naturligt, pulmonart, overfladeaktivt middel, fremgangsmåde til fremstilling heraf samt farmaceutiske midler indeholdende d DK172921B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2003287 1987-04-08
IT8720032A IT1203873B (it) 1987-04-08 1987-04-08 Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e

Publications (3)

Publication Number Publication Date
DK190088D0 DK190088D0 (da) 1988-04-07
DK190088A DK190088A (da) 1988-10-09
DK172921B1 true DK172921B1 (da) 1999-10-04

Family

ID=11163272

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198801900A DK172921B1 (da) 1987-04-08 1988-04-07 Naturligt, pulmonart, overfladeaktivt middel, fremgangsmåde til fremstilling heraf samt farmaceutiske midler indeholdende d

Country Status (22)

Country Link
US (1) US5024995A (de)
EP (1) EP0286011B1 (de)
JP (1) JP2700323B2 (de)
AT (1) ATE99949T1 (de)
AU (1) AU619462B2 (de)
CA (1) CA1320440C (de)
DE (2) DE286011T1 (de)
DK (1) DK172921B1 (de)
EG (1) EG19626A (de)
ES (1) ES2004856T3 (de)
FI (1) FI92905C (de)
GR (1) GR890300026T1 (de)
HK (1) HK1007103A1 (de)
HU (1) HU211950A9 (de)
IE (1) IE61384B1 (de)
IT (1) IT1203873B (de)
MY (1) MY103260A (de)
NO (1) NO174733C (de)
NZ (1) NZ224146A (de)
PH (1) PH25300A (de)
PT (1) PT87188B (de)
ZA (1) ZA882416B (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8803713D0 (sv) * 1988-10-18 1988-10-18 Kabigen Ab Biologically active lipoprotein and its use
DE3921954A1 (de) * 1989-07-04 1991-01-17 Thomae Gmbh Dr K Niedrig-viskose, hochkonzentrierte surfactant-suspension
AU660612B2 (en) * 1990-05-18 1995-07-06 Mitsubishi-Tokyo Pharmaceuticals, Inc. Remedy for asthma
US5437272A (en) * 1991-05-01 1995-08-01 Alliance Pharmaceutical Corp. Perfluorocarbon associated gas exchange
EP0908178A1 (de) 1991-05-03 1999-04-14 Alliance Pharmaceutical Corporation Partielle Flüssigkeitsbeatmung mittels Fluorkohlenwasserstoffen
EP0808636A1 (de) * 1991-11-14 1997-11-26 Alliance Pharmaceutical Corporation Verfahren zur teilweisen flüssigen Beatmung mit Fluorkohlwasserstoffen
IT1255967B (it) * 1992-11-27 1995-11-17 Chiesi Farma Spa Procedimento per la purificazione di materiale surfattante polmonare naturale con l'impiego di fluidi supercritici
US5531219A (en) * 1994-11-04 1996-07-02 Alliance Pharmaceutical Corp. Use of liquid fluorocarbons to facilitate pulmonary drug delivery
CO5021218A1 (es) * 1994-12-29 2001-03-27 Ct Nac De Sanidad Agropecuaria Surfactante pulmonar natural porcino
US6129934A (en) * 1995-06-07 2000-10-10 Ony, Inc. Modification of animal lung surfactant for treating respiratory disease due to lung surfactant deficiency or dysfunction
US6172203B1 (en) * 1996-02-07 2001-01-09 Alfredo Adolfo Hager Method for extracting and purifying pulmonary surfactant
WO1997029738A1 (en) * 1996-02-16 1997-08-21 The Administrators Of The Tulane Educational Fund Methods and compositions for treating eustachian tube dysfunction by inhalation
AU6083899A (en) 1999-09-16 2001-04-17 Aventis Behring Gmbh Combination of c1-inh and lung surfactant for the treatment of respiratory disorders
US6676930B2 (en) 1999-11-28 2004-01-13 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
US6156294A (en) 1999-11-28 2000-12-05 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
DE19957898A1 (de) * 1999-12-01 2001-06-07 Byk Gulden Lomberg Chem Fab Neue Verwendung von Lungensurfactant
DE10018022A1 (de) * 2000-04-12 2001-10-31 Byk Gulden Lomberg Chem Fab Neue Verwendung von Lungensurfactant zur Prophylaxe oder Frühbehandlung von akuten Lungenerkrankungen
JP4559731B2 (ja) 2001-10-11 2010-10-13 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 肺サーファクタントの新規使用
US8236750B2 (en) 2004-08-06 2012-08-07 Nycomed Gmbh Composition comprising a pulmonary surfactant and a TNF-derived peptide
US7582312B2 (en) * 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
US8337815B2 (en) * 2004-12-23 2012-12-25 Discovery Laboratories, Inc. Pulmonary surfactant formulations
SI1841458T1 (sl) 2005-01-06 2012-04-30 Discovery Lab Inc Zdravljenje s predpisanim odmerjanjem surfaktanta za zdravljenje ali preprečevanje bronhopulmonalne displazije
GB2426703B (en) * 2005-05-31 2007-09-19 Malvern Cosmeceutics Ltd Compositions
KR20090060348A (ko) * 2006-09-19 2009-06-11 디스커버리 래보래토리스, 인크. 폐 계면활성제 제제 및 점액 클리어런스 촉진 방법
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
DE102007025898A1 (de) * 2007-06-01 2008-12-04 Matthias W. Dr. Amrein Behandlung von Surfactanten
CA2744940A1 (en) 2008-12-10 2010-06-17 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of medicaments to the lungs
CN110996977A (zh) * 2017-07-07 2020-04-10 利珀生物实验室株式会社 用于缓解或治疗灼伤及褥疮的组合物
US11219843B2 (en) * 2019-07-08 2022-01-11 Nik Paya Karen Pharmed Extraction of animal-derived pulmonary surfactants
EP4366691A1 (de) 2021-07-05 2024-05-15 Chiesi Farmaceutici S.p.A. Verfahren zur herstellung eines lungensurfactants

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55160721A (en) * 1979-06-02 1980-12-13 Tokyo Tanabe Co Ltd Pulmonary surfactant ta-546, its preparation, and remedy for pulmonary hyaline membrane syndrome comprising it as active constituent
US4312860A (en) * 1980-10-24 1982-01-26 Regents Of The University Of California Lung surfactant compositions
JPS5845299A (ja) * 1981-09-10 1983-03-16 東京田辺製薬株式会社 新規な表面活性物質、その製造法及びそれを含有する呼吸窮迫疾候群治療剤
JPS58222022A (ja) * 1982-06-21 1983-12-23 Teijin Ltd 合成肺表面活性剤及びそれを有効成分とする呼吸窮迫症候群治療剤
JPS59164724A (ja) * 1983-03-10 1984-09-17 Tokyo Tanabe Co Ltd サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤
BG49073A1 (en) * 1983-12-08 1991-08-15 Dresden Arzneimittel Remedy for treatment of asthmatic syndrome caused by lack of surface- active substance and method for obtaining it
JPS6165821A (ja) * 1984-09-07 1986-04-04 Tokyo Tanabe Co Ltd 合成サ−フアクタント及びそれを有効成分とする肺表面活性物質喪失性無気肺の治療剤
FR2586587B1 (fr) * 1985-08-30 1987-10-23 Adir Nouveaux surfactants artificiels, leur preparation et les compositions pharmaceutiques qui les contiennent.
EP0273916A4 (de) * 1986-05-06 1989-11-30 Childrens Hosp Medical Center Lungenhydrophobes, an ein oberflächenaktives mittel assoziiertes protein von 6000 dalton molekulargewicht sowie multimere davon.

Also Published As

Publication number Publication date
IT1203873B (it) 1989-02-23
HU211950A9 (en) 1996-01-29
FI92905B (fi) 1994-10-14
PT87188A (pt) 1988-05-01
IE881008L (en) 1988-10-08
DK190088D0 (da) 1988-04-07
IT8720032A0 (it) 1987-04-08
EP0286011B1 (de) 1994-01-12
NO881515D0 (no) 1988-04-07
FI881508A0 (fi) 1988-03-30
EP0286011A3 (en) 1990-02-07
ES2004856T3 (es) 1994-12-16
AU1433788A (en) 1988-10-13
JPS6463526A (en) 1989-03-09
GR890300026T1 (en) 1989-04-12
US5024995A (en) 1991-06-18
IE61384B1 (en) 1994-11-02
FI881508A (fi) 1988-10-09
NO881515L (no) 1988-10-10
NO174733B (no) 1994-03-21
DE3886970D1 (de) 1994-02-24
CA1320440C (en) 1993-07-20
ZA882416B (en) 1988-09-28
ES2004856A4 (es) 1989-02-16
PH25300A (en) 1991-04-30
JP2700323B2 (ja) 1998-01-21
DE286011T1 (de) 1989-03-09
DK190088A (da) 1988-10-09
ATE99949T1 (de) 1994-01-15
MY103260A (en) 1993-05-29
EG19626A (en) 1995-09-30
AU619462B2 (en) 1992-01-30
NO174733C (no) 1994-06-29
DE3886970T2 (de) 1994-05-26
PT87188B (pt) 1992-07-31
NZ224146A (en) 1991-06-25
EP0286011A2 (de) 1988-10-12
HK1007103A1 (en) 1999-04-01
FI92905C (fi) 1995-01-25

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Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired