DK1719775T3 - Camptotheciner med en modificeret lactonring - Google Patents

Camptotheciner med en modificeret lactonring

Info

Publication number
DK1719775T3
DK1719775T3 DK06116366T DK06116366T DK1719775T3 DK 1719775 T3 DK1719775 T3 DK 1719775T3 DK 06116366 T DK06116366 T DK 06116366T DK 06116366 T DK06116366 T DK 06116366T DK 1719775 T3 DK1719775 T3 DK 1719775T3
Authority
DK
Denmark
Prior art keywords
camptothecins
lactone ring
modified lactone
modified
ring
Prior art date
Application number
DK06116366T
Other languages
Danish (da)
English (en)
Inventor
Mauro Marzi
Elena Marastoni
Sergio Penco
Claudio Pisano
Maria Ornella Tinti
Loredana Vesci
Franco Zunino
Domenico Vergani
Walter Cabri
Marco Alpegiani
Martin Patricio
Tamara Danelli
Original Assignee
Sigma Tau Ind Farmaceuti
Ist Naz Stud Cura Dei Tumori
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti, Ist Naz Stud Cura Dei Tumori filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of DK1719775T3 publication Critical patent/DK1719775T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epoxy Compounds (AREA)
DK06116366T 2002-05-31 2003-05-28 Camptotheciner med en modificeret lactonring DK1719775T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2002RM000305A ITRM20020305A1 (it) 2002-05-31 2002-05-31 Camptotecine con anello lattonico modificato.
PCT/IT2003/000328 WO2003101995A2 (en) 2002-05-31 2003-05-28 Camptothecins with a modified lactone ring

Publications (1)

Publication Number Publication Date
DK1719775T3 true DK1719775T3 (da) 2008-11-17

Family

ID=11456338

Family Applications (2)

Application Number Title Priority Date Filing Date
DK03730480.5T DK1511752T5 (da) 2002-05-31 2003-05-28 Camptotheciner med modificeret lactonring
DK06116366T DK1719775T3 (da) 2002-05-31 2003-05-28 Camptotheciner med en modificeret lactonring

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK03730480.5T DK1511752T5 (da) 2002-05-31 2003-05-28 Camptotheciner med modificeret lactonring

Country Status (22)

Country Link
US (1) US7273873B2 (it)
EP (2) EP1511752B3 (it)
JP (1) JP4693410B2 (it)
KR (1) KR101042042B1 (it)
CN (1) CN1656100A (it)
AR (1) AR040139A1 (it)
AT (2) ATE403659T1 (it)
AU (2) AU2003241160B2 (it)
BR (2) BR0311333A (it)
CA (2) CA2485201C (it)
CY (2) CY1107311T1 (it)
DE (2) DE60308368T3 (it)
DK (2) DK1511752T5 (it)
ES (2) ES2312090T3 (it)
IT (1) ITRM20020305A1 (it)
MX (1) MXPA04011682A (it)
PE (1) PE20050120A1 (it)
PL (1) PL374346A1 (it)
PT (2) PT1719775E (it)
SI (2) SI1719775T1 (it)
TW (1) TWI325866B (it)
WO (1) WO2003101995A2 (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2852606A1 (fr) * 2003-03-18 2004-09-24 Inst Nat Sante Rech Med Moyens pour inhiber simultanement l'expression de plusieurs genes impliques dans une pathologie
ITRM20030344A1 (it) * 2003-07-14 2005-01-15 Ist Naz Stud Cura Dei Tumori 7-n-poliamminoalchil(ossi)imminometilcamptotecine recanti gruppi protettivi.
EP2170900B1 (en) 2007-08-01 2012-12-12 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Crystalline form ii of 7-(dimethoxy-methyl) camptothecin, its use as intermediate and products obtained therefrom
CN102746314B (zh) * 2011-04-18 2016-07-06 华东师范大学 含有稳定7元内酯环的喜树碱类化合物、制备方法和用途
CN104530066A (zh) * 2015-01-06 2015-04-22 华东师范大学 一类新型高喜树碱衍生物、制备方法和用途
CN113811333B (zh) 2019-05-14 2024-03-12 诺维逊生物股份有限公司 靶向抗癌核激素受体的化合物
US11952349B2 (en) 2019-11-13 2024-04-09 Nuvation Bio Inc. Anti-cancer nuclear hormone receptor-targeting compounds
IL306010A (en) * 2021-03-23 2023-11-01 Nuvation Bio Inc Anticancer compounds against the nuclear hormone receptor
US12006314B2 (en) 2021-05-03 2024-06-11 Nuvation Bio Inc. Anti-cancer nuclear hormone receptor-targeting compounds
WO2024073626A2 (en) * 2022-09-28 2024-04-04 Nuvation Bio Inc. Anti-cancer nuclear hormone receptor-targeting compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57116076A (en) * 1981-01-09 1982-07-19 Yakult Honsha Co Ltd Novel camptothecin derivative and its preparation
US4399276A (en) * 1981-01-09 1983-08-16 Kabushiki Kaisha Yakult Honsha 7-Substituted camptothecin derivatives
FR2532591A1 (fr) 1982-09-02 1984-03-09 Hutchinson Nouveau dispositif de securite pour pneumatiques de vehicules ou autres engins
RU2164515C2 (ru) * 1995-06-21 2001-03-27 Сосьете де Консей де Решерш э Д'Аппликасьон Сьентифик (СКРАС) Соединения камптотецина, способы их получения, промежуточные соединения и терапевтические композиции
ATE216998T1 (de) * 1999-03-09 2002-05-15 Sigma Tau Ind Farmaceuti Camptothecin-derivate mit antitumor-wirkung

Also Published As

Publication number Publication date
MXPA04011682A (es) 2005-03-31
JP2005531602A (ja) 2005-10-20
PL374346A1 (en) 2005-10-17
WO2003101995A8 (en) 2004-12-23
DK1511752T5 (da) 2010-06-14
CY1108793T1 (el) 2014-04-09
TWI325866B (en) 2010-06-11
AU2009236044B8 (en) 2011-07-21
TW200404806A (en) 2004-04-01
KR20050036909A (ko) 2005-04-20
EP1719775B1 (en) 2008-08-06
PT1511752E (pt) 2007-01-31
EP1511752B1 (en) 2006-09-13
BR0311329A (pt) 2005-02-22
SI1719775T1 (sl) 2009-04-30
CA2485201C (en) 2010-11-02
SI1511752T1 (sl) 2007-02-28
ES2273002T7 (es) 2011-08-01
DE60308368T2 (de) 2007-09-06
EP1511752A2 (en) 2005-03-09
AU2009236044A1 (en) 2009-12-03
PT1719775E (pt) 2008-09-30
DK1511752T3 (da) 2007-01-29
CY1107311T1 (el) 2012-11-21
EP1719775A1 (en) 2006-11-08
US20050154003A1 (en) 2005-07-14
ITRM20020305A0 (it) 2002-05-31
AU2003241160A1 (en) 2003-12-19
EP1511752B8 (en) 2007-04-18
WO2003101995A3 (en) 2004-02-19
CN1656100A (zh) 2005-08-17
CA2485201A1 (en) 2003-12-11
DE60308368D1 (de) 2006-10-26
AU2009236044B2 (en) 2011-03-24
ES2312090T3 (es) 2009-02-16
AU2003241160B2 (en) 2009-08-20
KR101042042B1 (ko) 2011-06-16
CA2706635A1 (en) 2003-12-11
AU2009236044A8 (en) 2011-07-21
ES2273002T3 (es) 2007-05-01
EP1511752B3 (en) 2010-03-10
DE60322754D1 (de) 2008-09-18
AR040139A1 (es) 2005-03-16
ITRM20020305A1 (it) 2003-12-01
DE60308368T3 (de) 2010-09-16
BR0311333A (pt) 2005-03-15
US7273873B2 (en) 2007-09-25
PE20050120A1 (es) 2005-03-04
ATE339422T1 (de) 2006-10-15
JP4693410B2 (ja) 2011-06-01
ATE403659T1 (de) 2008-08-15
WO2003101995A2 (en) 2003-12-11

Similar Documents

Publication Publication Date Title
DE60330079D1 (de) Ölring
NO20054339D0 (no) Forede bronnboringer med maksimal diameter
DK1490133T3 (da) Infusionsanordning med lavprofildrejeforbindelse
DK2266650T3 (da) Lægemiddeldispenser
DK1583763T3 (da) Benzoazolylpiperazinderivater med VR1-antagonistaktivitet
DK1560835T3 (da) Spirocykliske cyclohexan-derivater
DE03726967T1 (de) Wirbelringerzeuger
FR2837895B1 (fr) Segment de piston
ATE453811T1 (de) Synchronring
DE60332581D1 (de) Induktiver Stellungsgeber
DE112005001543T5 (de) Entlüfteter Einspritzventil-Aussenring
DE60332694D1 (de) Näherungssensor
DK1719775T3 (da) Camptotheciner med en modificeret lactonring
DE60239391D1 (de) rgungsringes mit großem parasitärem Widerstand
FI20030333A0 (fi) MSM-anturi
FR2847399B1 (fr) Recepteur a configuration double
DE50307081D1 (de) Gabelbrücke
FR2838029B1 (fr) Bague
DE10393274D2 (de) Palettiergerät
FI20020799A0 (fi) Voimalaite
FR2848277B1 (fr) Segment de piston
ATA16062002A (de) Schlüsselanhänger
DE20318238U1 (de) Beissring
ES1052520Y (es) Dispositivo anillo abre-botellas
FI20031897A0 (fi) Rengas