DK170277B1 - Sulfonsyreestere samt fremgangsmåder til deres fremstilling - Google Patents

Sulfonsyreestere samt fremgangsmåder til deres fremstilling Download PDF

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Publication number
DK170277B1
DK170277B1 DK276386A DK276386A DK170277B1 DK 170277 B1 DK170277 B1 DK 170277B1 DK 276386 A DK276386 A DK 276386A DK 276386 A DK276386 A DK 276386A DK 170277 B1 DK170277 B1 DK 170277B1
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Denmark
Prior art keywords
formula
configuration
molecules
compound
compounds
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Application number
DK276386A
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Danish (da)
English (en)
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DK276386A (da
DK276386D0 (da
Inventor
Hans-Ulrich Blaser
Hans-Peter Jalett
Gottfried Sedelmeier
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK276386D0 publication Critical patent/DK276386D0/da
Publication of DK276386A publication Critical patent/DK276386A/da
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Publication of DK170277B1 publication Critical patent/DK170277B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Detergent Compositions (AREA)
DK276386A 1985-06-13 1986-06-12 Sulfonsyreestere samt fremgangsmåder til deres fremstilling DK170277B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH250185 1985-06-13
CH250185 1985-06-13

Publications (3)

Publication Number Publication Date
DK276386D0 DK276386D0 (da) 1986-06-12
DK276386A DK276386A (da) 1986-12-14
DK170277B1 true DK170277B1 (da) 1995-07-24

Family

ID=4235223

Family Applications (2)

Application Number Title Priority Date Filing Date
DK276386A DK170277B1 (da) 1985-06-13 1986-06-12 Sulfonsyreestere samt fremgangsmåder til deres fremstilling
DK39695A DK171950B1 (da) 1985-06-13 1995-04-07 Anvendelse af sulfon-syreestere til fremstilling af ACE-haemmere og/eller analoger

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK39695A DK171950B1 (da) 1985-06-13 1995-04-07 Anvendelse af sulfon-syreestere til fremstilling af ACE-haemmere og/eller analoger

Country Status (18)

Country Link
US (2) US4785089A (pt)
EP (1) EP0206993B1 (pt)
JP (2) JPS61289073A (pt)
KR (1) KR940007529B1 (pt)
AT (1) ATE53014T1 (pt)
CA (1) CA1338089C (pt)
CY (1) CY1710A (pt)
DD (2) DD283611A5 (pt)
DE (1) DE3671439D1 (pt)
DK (2) DK170277B1 (pt)
ES (2) ES8801197A1 (pt)
FI (1) FI86171C (pt)
HK (1) HK63293A (pt)
HU (1) HU203074B (pt)
IE (1) IE58477B1 (pt)
IL (1) IL79077A (pt)
PT (1) PT82744B (pt)
SG (1) SG32393G (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166354B1 (en) * 1984-06-26 1992-08-05 Merck & Co. Inc. Benzofused lactam compounds and pharmaceutical compositions containing them
US4785089A (en) * 1985-06-13 1988-11-15 Ciba-Geigy Corporation Novel sulfonic acid esters and their preparation
US5145864A (en) * 1987-09-15 1992-09-08 Alcoholism And Drug Addiction Research Foundation Reduction of voluntary alcohol consumption by treatment with angiotensin converting enzyme inhibitors
US5110813A (en) * 1987-09-15 1992-05-05 Alcoholism And Drug Addiction Research Foundation Reduction of voluntary alcohol consumption by treatment with angiotensin converting enzyme inhibitors
US5371014A (en) * 1988-02-12 1994-12-06 Daicel Chemical Industries, Ltd. Process for the production of optically active 2-hydroxy acid esters using microbes to reduce the 2-oxo precursor
ATE98697T1 (de) * 1988-06-06 1994-01-15 Ciba Geigy Ag Verfahren zur herstellung von hydroxysaeuren.
JP3915015B2 (ja) 1995-08-22 2007-05-16 味の素株式会社 光学活性２−ヒドロキシ−４−アリール酪酸またはそのエステルの製造方法
EP1070042A2 (en) * 1998-03-31 2001-01-24 Ciba SC Holding AG Process for the preparation of hpb esters
AU2000239828A1 (en) * 2000-04-18 2001-10-30 Scinopharm Singapore Pte Ltd Process for preparation of 3-((1'-(alkoxycarbonyl)-3'-phenylpropyl)amino)-2-oxo-(1)- benzazepine and its derivatives
CN1585744A (zh) * 2001-03-27 2005-02-23 兰贝克赛实验室有限公司 贝那普利的制备方法
EP1291336A3 (en) * 2001-09-05 2003-10-08 Solvias AG Preparation of optically active alpha-hydroxyethers
ITMI20020934A1 (it) 2002-05-03 2003-11-03 Danimite Dipharma S P A Processo per la sintesi di benazepril cloridrato
AU2003247159A1 (en) * 2003-07-07 2005-01-21 Hetero Drugs Limited A novel process for the preparation of cilazapril
US20090082559A1 (en) * 2005-05-12 2009-03-26 Lupin Limited Process for Crystallization of Benazepril Hydrochloride
CN105061312B (zh) * 2015-07-17 2017-12-12 惠州信立泰药业有限公司 一种改进的盐酸贝那普利的制备方法及含有该盐酸贝那普利的药物组合物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5535060A (en) * 1978-09-05 1980-03-11 Agency Of Ind Science & Technol Asymmetric hydrogenation of alpha-keto-acid ester
JPS5823861B2 (ja) * 1979-06-05 1983-05-18 工業技術院長 α−ケトエステルの不斉水素化方法
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4374847A (en) * 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids
CY1403A (en) * 1981-08-11 1987-12-18 Ciba Geigy Ag Benzazepin-2-ones
US4410520A (en) * 1981-11-09 1983-10-18 Ciba-Geigy Corporation 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
EP0081320A3 (en) * 1981-12-07 1984-07-18 Beecham Group Plc Preparation of acetic acid derivatives
US4473575A (en) * 1982-07-19 1984-09-25 Ciba-Geigy Corporation 3-Amino-(1)-benzazepin-2-one-1-alkanoic acids
US4470988A (en) * 1983-02-10 1984-09-11 Ciba-Geigy Corporation Benzazocinone and benzazoninone derivatives, and their pharmaceutical use
DE3315464A1 (de) * 1983-04-28 1984-10-31 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern
DE3328986A1 (de) * 1983-08-11 1985-02-21 Degussa Ag, 6000 Frankfurt Verfahren zur praktisch stereospezifischen herstellung von optisch aktiven (alpha)-aminocarbonsaeureestern
US4785089A (en) * 1985-06-13 1988-11-15 Ciba-Geigy Corporation Novel sulfonic acid esters and their preparation

Also Published As

Publication number Publication date
HK63293A (en) 1993-07-09
ES555954A0 (es) 1987-12-16
JPH0567140B2 (pt) 1993-09-24
DD283611A5 (de) 1990-10-17
DD266097A5 (de) 1989-03-22
IL79077A0 (en) 1986-09-30
FI86171B (fi) 1992-04-15
JPH0735358B2 (ja) 1995-04-19
ES8801197A1 (es) 1987-12-16
FI86171C (fi) 1992-07-27
KR870000291A (ko) 1987-02-17
EP0206993B1 (de) 1990-05-23
PT82744B (pt) 1988-12-15
DK171950B1 (da) 1997-08-25
FI862462A (fi) 1986-12-14
ES8802013A1 (es) 1988-03-16
JPS61289073A (ja) 1986-12-19
DK276386A (da) 1986-12-14
DE3671439D1 (de) 1990-06-28
IE861571L (en) 1986-11-13
EP0206993A1 (de) 1986-12-30
HU203074B (en) 1991-05-28
IE58477B1 (en) 1993-09-22
CA1338089C (en) 1996-02-27
DK276386D0 (da) 1986-06-12
IL79077A (en) 1994-01-25
PT82744A (en) 1986-07-01
KR940007529B1 (ko) 1994-08-19
JPH05310656A (ja) 1993-11-22
CY1710A (en) 1994-01-14
FI862462A0 (fi) 1986-06-09
ATE53014T1 (de) 1990-06-15
DK39695A (da) 1995-04-07
SG32393G (en) 1993-05-21
US5066801A (en) 1991-11-19
ES557722A0 (es) 1988-03-16
US4785089A (en) 1988-11-15

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Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired