DK169308B1 - Lyofiliseret præparat, fremgangsmåde til fremstilling af et ifosfamidlyofilisatpræparat samt ifosfamidlyofilisatpræparatet opnået ved fremgangsmåden - Google Patents

Lyofiliseret præparat, fremgangsmåde til fremstilling af et ifosfamidlyofilisatpræparat samt ifosfamidlyofilisatpræparatet opnået ved fremgangsmåden Download PDF

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Publication number
DK169308B1
DK169308B1 DK569687A DK569687A DK169308B1 DK 169308 B1 DK169308 B1 DK 169308B1 DK 569687 A DK569687 A DK 569687A DK 569687 A DK569687 A DK 569687A DK 169308 B1 DK169308 B1 DK 169308B1
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DK
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Prior art keywords
ifosfamide
weight
preparation
solution
hexitol
Prior art date
Application number
DK569687A
Other languages
Danish (da)
English (en)
Other versions
DK569687D0 (da
DK569687A (da
Inventor
Dieter Sauerbier
Uwe-Peter Dammann
Otto Isaac
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of DK569687D0 publication Critical patent/DK569687D0/da
Publication of DK569687A publication Critical patent/DK569687A/da
Application granted granted Critical
Publication of DK169308B1 publication Critical patent/DK169308B1/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)
  • Control Of El Displays (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Amplifiers (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Indole Compounds (AREA)
DK569687A 1986-10-31 1987-10-30 Lyofiliseret præparat, fremgangsmåde til fremstilling af et ifosfamidlyofilisatpræparat samt ifosfamidlyofilisatpræparatet opnået ved fremgangsmåden DK169308B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3637089 1986-10-31
DE3637089 1986-10-31

Publications (3)

Publication Number Publication Date
DK569687D0 DK569687D0 (da) 1987-10-30
DK569687A DK569687A (da) 1988-05-01
DK169308B1 true DK169308B1 (da) 1994-10-10

Family

ID=6312873

Family Applications (1)

Application Number Title Priority Date Filing Date
DK569687A DK169308B1 (da) 1986-10-31 1987-10-30 Lyofiliseret præparat, fremgangsmåde til fremstilling af et ifosfamidlyofilisatpræparat samt ifosfamidlyofilisatpræparatet opnået ved fremgangsmåden

Country Status (25)

Country Link
EP (1) EP0265812B1 (ko)
JP (1) JPS63159319A (ko)
KR (1) KR900003491B1 (ko)
AT (1) ATE55250T1 (ko)
AU (1) AU598602B2 (ko)
CA (1) CA1314231C (ko)
DD (1) DD262582A5 (ko)
DE (1) DE3764235D1 (ko)
DK (1) DK169308B1 (ko)
EG (1) EG18333A (ko)
ES (1) ES2017982B3 (ko)
FI (1) FI87140C (ko)
GE (1) GEP19971025B (ko)
GR (1) GR3000708T3 (ko)
HU (1) HU197987B (ko)
IL (1) IL84312A (ko)
IN (1) IN168119B (ko)
LV (1) LV10051B (ko)
MX (1) MX8958A (ko)
NO (1) NO873860L (ko)
PT (1) PT86032B (ko)
RU (1) RU1836079C (ko)
UA (1) UA11075A (ko)
YU (1) YU197387A (ko)
ZA (1) ZA878183B (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0334083B1 (de) * 1988-03-19 1991-07-24 ASTA Pharma Aktiengesellschaft Ifosfamid-Mesna-Lyophilisat und Verfahren zu dessen Herstellung
US5227373A (en) * 1991-10-23 1993-07-13 Bristol-Myers Squibb Co. Lyophilized ifosfamide compositions
WO1995007083A1 (en) * 1993-09-10 1995-03-16 F.H. Faulding & Co. Limited Ifosfamide lyophilisate composition
DE19529057B4 (de) * 1995-08-08 2007-12-13 Baxter Healthcare S.A. Ifosfamid-Lyophilisat-Zubereitungen
KR20010034552A (ko) * 1998-03-03 2001-04-25 요시히코 시오노 포스포리파제 저해제인 소듐[[3-(2-아미노-1,2-디옥소에틸)-2-에틸-1-(페닐메틸)-1ｈ-인돌-4-일]옥시]아세테이트를 포함하는 약학적 조성물
JP2006508917A (ja) * 2002-09-05 2006-03-16 ブハラット セルムズ アンド ヴァクシンズ リミテッド メスナを有する、オキサザホスホリンの液体安定性組成物
KR101066181B1 (ko) * 2002-12-02 2011-09-20 바라트 쎄럼스 앤드 백신스 리미티드 비경구 투여용 아이포스파마이드 조성물 및 이의 제조방법
US8436190B2 (en) * 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
PL2071917T3 (pl) * 2006-09-29 2013-04-30 Infa Sa System opakowaniowy dla kompozycji farmaceutycznych oraz zestaw do podawania dożylnego
WO2016087001A1 (en) * 2014-12-04 2016-06-09 Huawei Technologies Co., Ltd. Load allocation in a data communication network

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732340A (en) * 1966-07-11 1973-05-08 Asta Werke Ag Chem Fab N',o-propylene phosphoric acid ester diamides
DE2750207A1 (de) * 1977-05-09 1978-11-16 Walton J Smith Gefriergetrocknete zusammensetzungen, insbesondere gefriergetrocknete pharmazeutische praeparate und verfahren zu deren herstellung
DE3279834D1 (en) * 1981-12-31 1989-08-31 Asta Pharma Ag 4-sulfido-oxaza phosphorines and their use in the treatment of cancer, and in immunosuppression
US4537883A (en) * 1982-11-12 1985-08-27 Mead Johnson & Company Lyophilized cyclophosphamide

Also Published As

Publication number Publication date
ZA878183B (en) 1988-05-02
UA11075A (uk) 1996-12-25
GR3000708T3 (en) 1991-10-10
JPS63159319A (ja) 1988-07-02
DK569687D0 (da) 1987-10-30
MX8958A (es) 1993-12-01
DK569687A (da) 1988-05-01
ES2017982B3 (es) 1991-03-16
KR880004814A (ko) 1988-06-27
FI874727A (fi) 1988-05-01
NO873860D0 (no) 1987-09-15
NO873860L (no) 1988-05-02
JPH0543684B2 (ko) 1993-07-02
KR900003491B1 (ko) 1990-05-21
IL84312A0 (en) 1988-03-31
CA1314231C (en) 1993-03-09
GEP19971025B (en) 1997-04-06
FI87140B (fi) 1992-08-31
PT86032B (pt) 1990-08-31
LV10051B (en) 1995-06-20
FI874727A0 (fi) 1987-10-27
FI87140C (fi) 1992-12-10
HU197987B (en) 1989-07-28
PT86032A (de) 1987-11-01
ATE55250T1 (de) 1990-08-15
EG18333A (en) 1993-12-30
DE3764235D1 (de) 1990-09-13
AU8052987A (en) 1988-05-05
EP0265812A1 (de) 1988-05-04
AU598602B2 (en) 1990-06-28
LV10051A (lv) 1994-05-10
RU1836079C (ru) 1993-08-23
EP0265812B1 (de) 1990-08-08
DD262582A5 (de) 1988-12-07
YU197387A (en) 1988-12-31
IN168119B (ko) 1991-02-09
IL84312A (en) 1991-11-21
HUT44932A (en) 1988-05-30

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired