DK164392C - Anvendelse af 3'-azido-3'-desoxythymidin til fremstilling af et laegemiddel til behandling af eller profylakse for en human retrovirusinfektion - Google Patents
Anvendelse af 3'-azido-3'-desoxythymidin til fremstilling af et laegemiddel til behandling af eller profylakse for en human retrovirusinfektionInfo
- Publication number
- DK164392C DK164392C DK118086A DK118086A DK164392C DK 164392 C DK164392 C DK 164392C DK 118086 A DK118086 A DK 118086A DK 118086 A DK118086 A DK 118086A DK 164392 C DK164392 C DK 164392C
- Authority
- DK
- Denmark
- Prior art keywords
- desoxythymidine
- prophylaxy
- azido
- medicine
- prepare
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK199102026A DK175122B1 (da) | 1985-03-16 | 1991-12-18 | Farmaceutisk præparat omfattende et farmaceutisk acceptabelt derivat af 3'azido-3'-desoxythymidin samt fremgangsmåde til fremstilling deraf |
DK199102027A DK175192B1 (da) | 1985-03-16 | 1991-12-18 | Farmaceutisk præparat med indhold af 3'-azido-3'-desoxythymidin som aktiv ingrediens samt 3'-azido-3'-desoxythymidin til anvendelse mod en human retrovirusinfektion |
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858506869A GB8506869D0 (en) | 1985-03-16 | 1985-03-16 | Antiviral compound |
GB8506869 | 1985-03-16 | ||
GB858511774A GB8511774D0 (en) | 1985-05-09 | 1985-05-09 | Antiviral compounds |
GB8511774 | 1985-05-09 | ||
US06/776,899 US4724232A (en) | 1985-03-16 | 1985-09-17 | Treatment of human viral infections |
US77689985 | 1985-09-17 | ||
GB8523881 | 1985-09-27 | ||
GB858523881A GB8523881D0 (en) | 1985-09-27 | 1985-09-27 | Antiviral compounds |
GB8603450 | 1986-02-12 | ||
GB868603450A GB8603450D0 (en) | 1986-02-12 | 1986-02-12 | Antiviral compounds |
Publications (4)
Publication Number | Publication Date |
---|---|
DK118086D0 DK118086D0 (da) | 1986-03-14 |
DK118086A DK118086A (da) | 1986-09-17 |
DK164392B DK164392B (da) | 1992-06-22 |
DK164392C true DK164392C (da) | 1992-11-09 |
Family
ID=27516579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK118086A DK164392C (da) | 1985-03-16 | 1986-03-14 | Anvendelse af 3'-azido-3'-desoxythymidin til fremstilling af et laegemiddel til behandling af eller profylakse for en human retrovirusinfektion |
Country Status (21)
Country | Link |
---|---|
EP (2) | EP0196185B1 (el) |
JP (1) | JPH0780898B2 (el) |
AP (1) | AP11A (el) |
AT (4) | ATE81978T1 (el) |
AU (1) | AU572019B2 (el) |
CA (1) | CA1238277A (el) |
CS (1) | CS385191A3 (el) |
CY (2) | CY1508A (el) |
DE (4) | DE3687069T2 (el) |
DK (1) | DK164392C (el) |
FI (1) | FI85978C (el) |
GR (1) | GR860712B (el) |
HK (2) | HK85789A (el) |
IE (1) | IE56503B1 (el) |
IL (1) | IL78158A (el) |
MC (1) | MC1742A1 (el) |
MY (1) | MY102693A (el) |
NZ (1) | NZ215486A (el) |
PH (1) | PH24388A (el) |
PT (1) | PT82199B (el) |
SG (1) | SG62889G (el) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2181128A (en) * | 1985-09-17 | 1987-04-15 | Wellcome Found | 3'-azidonucleosides |
US4841039A (en) * | 1986-05-01 | 1989-06-20 | Emory University | 2',3'-dideoxy-5-substituted uridines and related compounds as antiviral agents |
US4916122A (en) * | 1987-01-28 | 1990-04-10 | University Of Georgia Research Foundation, Inc. | 3'-Azido-2',3'-dideoxyuridine anti-retroviral composition |
US5084445A (en) * | 1986-05-01 | 1992-01-28 | University Of Georgia Research Foundation, Inc. | 3'-azido-2',3'-dideoxy-5-methylcytidine |
US5077279A (en) * | 1986-05-01 | 1991-12-31 | University Of Georgia Research Foundation, Inc. | 3'-azido-2',3'-dideoxy-5-methylcytidine anti-viral composition |
US4880782A (en) * | 1986-11-21 | 1989-11-14 | Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften E.V. | Method of treating viral infections in humans and compositions therefor |
JPH02500364A (ja) * | 1986-11-21 | 1990-02-08 | マツクス‐プランク‐ゲゼルシヤフト ツール フエルデルング デル ヴイツセンシヤフテン エー フアウ | ヒトにおけるウイルス感染の治療法およびそのための組成物 |
SE8605503D0 (sv) * | 1986-12-19 | 1986-12-19 | Astra Laekemedel Ab | Novel medicinal use |
US5190926A (en) * | 1987-01-28 | 1993-03-02 | University Of Georgia Research Foundation, Inc. | 3'-azido-2',3'-dideoxypyrimidines and related compounds as antiviral agents |
ES2039615T3 (es) * | 1987-03-16 | 1993-10-01 | The Wellcome Foundation Limited | Un procedimiento para la preparacion de nucleosidos. |
EP0286825A3 (en) * | 1987-03-18 | 1989-04-12 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Use of 3'-fluro-3' deoxythymidine for the manufacture of a medicament for the treatment of virus infections |
EP0282618A1 (en) * | 1987-03-18 | 1988-09-21 | Vereniging Het Nederlands Kanker Instituut | 1-Deoxynojirimycin as an anti-HIV therapeutic |
US4950652A (en) * | 1987-03-23 | 1990-08-21 | Hem Research, Inc. | dsRNAs for combination therapy in the treatment of viral diseases |
EP0292101A3 (en) * | 1987-03-25 | 1990-01-31 | The Wellcome Foundation Limited | Process for the preparation of 3'-azido-3'-deoxythymidine and intermediates |
GB8707421D0 (en) * | 1987-03-27 | 1987-04-29 | Wellcome Found | Pharmaceutical formulations |
IL86007A0 (en) * | 1987-04-09 | 1988-09-30 | Wellcome Found | 6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them |
US5185437A (en) * | 1987-04-09 | 1993-02-09 | Burroughs Wellcome Co. | Therapeutic nucleosides |
IL86009A (en) * | 1987-04-10 | 1991-09-16 | Us Health | Liposome-encapsulated phosphorylated nucleosides for treatment of retroviral diseases |
US5215970A (en) * | 1987-04-16 | 1993-06-01 | Medivir Ab | Nucleosides and nucleotide analogues, pharmaceutical composition and processes for the preparation of the compounds |
SE8701605D0 (sv) * | 1987-04-16 | 1987-04-16 | Astra Ab | Novel medicinal compounds |
DE3868125D1 (de) * | 1987-04-24 | 1992-03-12 | Wellcome Found | Antivirale mischungen. |
US4863927A (en) * | 1987-05-11 | 1989-09-05 | Merck & Co., Inc. | 1-(2-hydroxymethyl)cycloalkylmethyl)-5-substituted uracils |
YU110888A (en) * | 1987-06-10 | 1989-08-31 | Wellcome Found | Process for obtaining timine derivatives |
USRE33887E (en) * | 1987-06-22 | 1992-04-14 | Hoffmann-La Roche Inc. | Anti-retroviral compounds |
SU1548182A1 (ru) * | 1987-12-29 | 1990-03-07 | Институт молекулярной биологии АН СССР | 5 @ -Фосфонаты 3 @ -азидо-2 @ ,3 @ -дидезоксинуклеозидов, вл ющиес специфическими ингибиторами вируса СПИД в культуре лимфоцитов человека Н9/ШВ |
US5384396A (en) * | 1988-02-23 | 1995-01-24 | The University Of Georgia Research Foundation, Inc. | Process for the deoxygenation of nucleosides |
DE3824669C2 (de) * | 1988-07-20 | 1999-05-06 | Wondrak Ewald M | Verwendung von Trinatrium-Phosphonoformat |
US4987224A (en) * | 1988-08-02 | 1991-01-22 | University Of Georgia Research Foundation, Inc. | Method of preparation of 2',3'-dideoxynucleosides |
EP0355245A1 (fr) * | 1988-08-26 | 1990-02-28 | Michel Vandevelde | Utilisation d'agents d'inhibition de la réverse-transcriptase des rétrovirus |
HU205089B (en) * | 1989-05-31 | 1992-03-30 | Biogal Gyogyszergyar | Process for producing new thymine derivatives and pharmaceutical compositions comprising same |
ATE126053T1 (de) * | 1989-11-09 | 1995-08-15 | Asta Medica Ag | Arzneimittel, welche als wirkstoff schwefel enthaltende carbonsäuren enthalten sowie deren verwendung zur bekämpfung von retroviren. |
US5585367A (en) * | 1990-04-19 | 1996-12-17 | Previsan S.A. | Method of treating humans and animals infected with viruses of the retrovirus group |
DE69102764T2 (de) * | 1990-04-19 | 1995-02-09 | Previsan S.A., Luxemburg/Luxembourg | Azoische derivate, pharmazeutische und desinfektierende zusammensetzungen diese substanzen enthaltend, und deren verwendung gegen aids. |
GB9104740D0 (en) * | 1991-03-06 | 1991-04-17 | Wellcome Found | Antiviral nucleoside combination |
US6812233B1 (en) | 1991-03-06 | 2004-11-02 | Emory University | Therapeutic nucleosides |
IL102548A (en) * | 1991-08-02 | 1998-08-16 | Medivir Ab | Use of painting derivatives in the preparation of drugs for VIH inhibition and treatment of SDIA and new compounds |
US5593993A (en) * | 1991-08-02 | 1997-01-14 | Medivir Ab | Method for inhibition of HIV related viruses |
ATE184787T1 (de) * | 1992-05-13 | 1999-10-15 | Wellcome Found | Therapeutische kombinationen |
US6177435B1 (en) | 1992-05-13 | 2001-01-23 | Glaxo Wellcome Inc. | Therapeutic combinations |
GR920100326A (el) * | 1992-07-21 | 1994-03-31 | Medivir Ag | Ενώσεις και μέ?οδοι αναστολής του HIV και των σχετικών ιών. |
DE4336640A1 (de) * | 1993-10-22 | 1995-04-27 | Deutsches Rheuma Forschungszen | Neue Metallchelate, Verfahren zu deren Herstellung sowie deren Verwendung als antivirale Arzneimittel |
CA2270600A1 (en) | 1999-05-03 | 2000-11-03 | Infectio Recherche Inc. | Method and formulations for the treatment of diseases, particularly those caused by human immunodeficiency virus and leishmania |
EA007060B1 (ru) | 2001-10-26 | 2006-06-30 | Иституто Ди Ричерке Ди Биолоджиа Молеколаре П. Анджелетти Спа | N-замещённые гидроксипиримидинон-карбоксамидные ингибиторы вич интегразы |
EP2266590A3 (en) | 2002-02-22 | 2011-04-20 | Shire LLC | Active agent delivery sytems and methods for protecting and administering active agents |
EP1579862A1 (en) | 2004-03-25 | 2005-09-28 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure |
US8980894B2 (en) | 2004-03-25 | 2015-03-17 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure |
WO2022008025A1 (en) * | 2020-07-05 | 2022-01-13 | Since & Technology Development Fund Authority | 2-hydroxyiminopyrimidine nucleosides and derivitives and antiviral uses thereto |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3650492T2 (de) * | 1985-03-16 | 1996-10-31 | The Wellcome Foundation Ltd., London | Therapeutische Nukleoside |
-
1986
- 1986-03-14 DE DE8888101790T patent/DE3687069T2/de not_active Expired - Lifetime
- 1986-03-14 AT AT88101790T patent/ATE81978T1/de not_active IP Right Cessation
- 1986-03-14 AT AT86301897T patent/ATE44464T1/de not_active IP Right Cessation
- 1986-03-14 DE DE19863608606 patent/DE3608606A1/de not_active Withdrawn
- 1986-03-14 AT AT88101795T patent/ATE113603T1/de not_active IP Right Cessation
- 1986-03-14 MC MC861828A patent/MC1742A1/xx unknown
- 1986-03-14 DE DE3650130T patent/DE3650130T3/de not_active Expired - Lifetime
- 1986-03-14 AT AT0068386A patent/AT390000B/de not_active IP Right Cessation
- 1986-03-14 IL IL78158A patent/IL78158A/xx unknown
- 1986-03-14 DK DK118086A patent/DK164392C/da not_active IP Right Cessation
- 1986-03-14 IE IE677/86A patent/IE56503B1/en not_active IP Right Cessation
- 1986-03-14 DE DE198686301897T patent/DE196185T1/de active Pending
- 1986-03-14 EP EP86301897A patent/EP0196185B1/en not_active Expired
- 1986-03-14 EP EP88101790A patent/EP0291633B1/en not_active Expired - Lifetime
- 1986-03-14 AP APAP/P/1986/000027A patent/AP11A/en active
- 1986-03-14 PH PH33532A patent/PH24388A/en unknown
- 1986-03-14 CA CA000504126A patent/CA1238277A/en not_active Expired
- 1986-03-14 PT PT82199A patent/PT82199B/pt unknown
- 1986-03-14 NZ NZ215486A patent/NZ215486A/xx unknown
- 1986-03-14 AU AU54758/86A patent/AU572019B2/en not_active Expired
- 1986-03-14 GR GR860712A patent/GR860712B/el unknown
- 1986-03-14 FI FI861069A patent/FI85978C/fi not_active IP Right Cessation
- 1986-03-14 CY CY1508A patent/CY1508A/xx unknown
-
1987
- 1987-09-25 MY MYPI87001943A patent/MY102693A/en unknown
-
1988
- 1988-03-29 JP JP63073488A patent/JPH0780898B2/ja not_active Expired - Lifetime
-
1989
- 1989-09-11 SG SG628/89A patent/SG62889G/en unknown
- 1989-10-26 HK HK857/89A patent/HK85789A/xx not_active IP Right Cessation
-
1991
- 1991-12-17 CS CS913851A patent/CS385191A3/cs unknown
-
1995
- 1995-10-19 HK HK164395A patent/HK164395A/xx not_active IP Right Cessation
-
1996
- 1996-11-22 CY CY188996A patent/CY1889A/xx unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUP | Patent expired |