DE3650492T2 - Therapeutische Nukleoside - Google Patents
Therapeutische NukleosideInfo
- Publication number
- DE3650492T2 DE3650492T2 DE3650492T DE3650492T DE3650492T2 DE 3650492 T2 DE3650492 T2 DE 3650492T2 DE 3650492 T DE3650492 T DE 3650492T DE 3650492 T DE3650492 T DE 3650492T DE 3650492 T2 DE3650492 T2 DE 3650492T2
- Authority
- DE
- Germany
- Prior art keywords
- htlv
- azido
- against human
- animal
- therapeutic nucleosides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858506869A GB8506869D0 (en) | 1985-03-16 | 1985-03-16 | Antiviral compound |
GB858506868A GB8506868D0 (en) | 1985-03-16 | 1985-03-16 | Antibacterial compound |
GB858511774A GB8511774D0 (en) | 1985-05-09 | 1985-05-09 | Antiviral compounds |
GB858511775A GB8511775D0 (en) | 1985-05-09 | 1985-05-09 | Antibacterial compounds |
GB858523881A GB8523881D0 (en) | 1985-09-27 | 1985-09-27 | Antiviral compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3650492D1 DE3650492D1 (de) | 1996-04-11 |
DE3650492T2 true DE3650492T2 (de) | 1996-10-31 |
Family
ID=27516577
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3650492T Expired - Fee Related DE3650492T2 (de) | 1985-03-16 | 1986-03-14 | Therapeutische Nukleoside |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0199451B1 (de) |
JP (1) | JPH0723314B2 (de) |
AT (1) | ATE135011T1 (de) |
AU (1) | AU578809B2 (de) |
CA (1) | CA1285935C (de) |
DE (1) | DE3650492T2 (de) |
DK (1) | DK166805B1 (de) |
IE (1) | IE73219B1 (de) |
MY (1) | MY104069A (de) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6448392B1 (en) * | 1985-03-06 | 2002-09-10 | Chimerix, Inc. | Lipid derivatives of antiviral nucleosides: liposomal incorporation and method of use |
US5223263A (en) * | 1988-07-07 | 1993-06-29 | Vical, Inc. | Liponucleotide-containing liposomes |
KR860006987A (ko) * | 1985-03-16 | 1986-10-06 | 엠. 피. 잭슨 | 항 비루스성 뉴클레오시드의 제조방법 및 이것을 함유한 약학적 제형 제조방법 |
MC1742A1 (fr) * | 1985-03-16 | 1987-02-26 | Wellcome Found | Procede pour preparer un derive de 3'-azido-3'desoxythymigline et procede pour preparer une formulation pharmaceutique le contenant |
US4916122A (en) * | 1987-01-28 | 1990-04-10 | University Of Georgia Research Foundation, Inc. | 3'-Azido-2',3'-dideoxyuridine anti-retroviral composition |
US4841039A (en) * | 1986-05-01 | 1989-06-20 | Emory University | 2',3'-dideoxy-5-substituted uridines and related compounds as antiviral agents |
EP0332626A1 (de) * | 1986-11-21 | 1989-09-20 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Zubereitungen zur behandlung viraler infektionen bei menschen |
US4880782A (en) * | 1986-11-21 | 1989-11-14 | Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften E.V. | Method of treating viral infections in humans and compositions therefor |
US5190926A (en) * | 1987-01-28 | 1993-03-02 | University Of Georgia Research Foundation, Inc. | 3'-azido-2',3'-dideoxypyrimidines and related compounds as antiviral agents |
JPS63290894A (ja) * | 1987-03-16 | 1988-11-28 | ザ ウエルカム フアウンデーション リミテッド | 治療用ヌクレオシド |
EP0286825A3 (de) * | 1987-03-18 | 1989-04-12 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Verwendung von 3'-fluro-3'-deoxythymidine zur Herstellung von medicamenten zur Behandlung von Viruskrankheiten |
GB8707421D0 (en) * | 1987-03-27 | 1987-04-29 | Wellcome Found | Pharmaceutical formulations |
EP0516186A3 (en) * | 1987-04-16 | 1993-01-13 | Medivir Aktiebolag | Nucleosides and nucleoside analogues, pharmaceutical composition and processes for the preparation of the compounds |
SE8701605D0 (sv) * | 1987-04-16 | 1987-04-16 | Astra Ab | Novel medicinal compounds |
US5215970A (en) * | 1987-04-16 | 1993-06-01 | Medivir Ab | Nucleosides and nucleotide analogues, pharmaceutical composition and processes for the preparation of the compounds |
GB8712745D0 (en) * | 1987-05-30 | 1987-07-01 | Wellcome Found | Antiviral compounds |
US4804651A (en) * | 1987-06-09 | 1989-02-14 | Board Of Regents, The University Of Texas System | Methods and compositions for the treatment of psoriasis |
YU110888A (en) * | 1987-06-10 | 1989-08-31 | Wellcome Found | Process for obtaining timine derivatives |
USRE33887E (en) * | 1987-06-22 | 1992-04-14 | Hoffmann-La Roche Inc. | Anti-retroviral compounds |
US4837311A (en) * | 1987-06-22 | 1989-06-06 | Hoffman-La Roche Inc. | Anti-retroviral compounds |
SU1548182A1 (ru) * | 1987-12-29 | 1990-03-07 | Институт молекулярной биологии АН СССР | 5 @ -Фосфонаты 3 @ -азидо-2 @ ,3 @ -дидезоксинуклеозидов, вл ющиес специфическими ингибиторами вируса СПИД в культуре лимфоцитов человека Н9/ШВ |
GB8800276D0 (en) * | 1988-01-07 | 1988-02-10 | Univ Liverpool | Medical treatment |
FR2640267B2 (fr) * | 1988-01-19 | 1992-02-14 | Univ Paris Curie | Procede de synthese de l'azido-3(prime)-desoxy-3(prime)-thymidine et analogues |
FR2626001B1 (fr) * | 1988-01-19 | 1991-11-08 | Univ Paris Curie | Procede de synthese de l'azido-3ÿi1ÿ.-desoxy-3ÿi1ÿ.-thymidine et analogues |
US4921950A (en) * | 1988-06-09 | 1990-05-01 | Burroughs Wellcome Co. | Preparation of 3'azido-3-'-deoxythymidine |
US5817638A (en) * | 1988-07-07 | 1998-10-06 | Nexstar Pharmaceuticals, Inc. | Antiviral liponucleosides: treatment of hepatitis B |
US6252060B1 (en) | 1988-07-07 | 2001-06-26 | Nexstar Pharmaceuticals, Inc. | Antiviral liponucleosides: treatment of hepatitis B |
US6599887B2 (en) | 1988-07-07 | 2003-07-29 | Chimerix, Inc. | Methods of treating viral infections using antiviral liponucleotides |
SE8802687D0 (sv) * | 1988-07-20 | 1988-07-20 | Astra Ab | Nucleoside derivatives |
FR2635778A1 (fr) * | 1988-08-26 | 1990-03-02 | Ire Celltarg Sa | Nouveaux derives de la 3(prime) azido-3(prime) deoxythymidine (azt) actifs contre le virus hiv du sida |
IE980216A1 (en) * | 1989-04-17 | 2000-02-23 | Scotia Holdings Plc | Anti-virals |
HU205089B (en) * | 1989-05-31 | 1992-03-30 | Biogal Gyogyszergyar | Process for producing new thymine derivatives and pharmaceutical compositions comprising same |
FR2653771B1 (fr) * | 1989-10-27 | 1994-09-23 | Univ Paris Curie | Procede de preparation de l'azt (azido-3'-desoxy-3'-thymidine) et de composes apparentes. |
FR2656867A1 (fr) * | 1990-01-09 | 1991-07-12 | Centre Nat Rech Scient | Nouveau derives de la thymidine, leur preparation et les compositions qui les contiennent. |
FR2668153B1 (fr) * | 1990-10-22 | 1995-03-31 | Pasteur Merieux Serums Vacc | Nouveaux composes ribonucleosides, leur procede de preparation et les medicaments les contenant. |
US5451671A (en) * | 1992-07-27 | 1995-09-19 | Ajinomoto Co., Inc. | Method of purifying 2',3'-dideoxynucleosides |
EP0641352B1 (de) * | 1993-02-23 | 1997-06-04 | City Of Hope | 4-ethoxy-5-fluor-2'-deoxyuridine |
DE69533856T2 (de) * | 1994-10-24 | 2005-12-08 | Genencor International, Inc., Palo Alto | L-pyranosyl-nukleoside |
US5559101A (en) * | 1994-10-24 | 1996-09-24 | Genencor International, Inc. | L-ribofuranosyl nucleosides |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2134292A1 (en) * | 1971-04-30 | 1972-12-08 | Inst Nat Sante Rech Med | Interferon compsns - contg halo desoxyuridines rifamycine or rifampycine |
-
1986
- 1986-03-14 IE IE67686A patent/IE73219B1/en not_active IP Right Cessation
- 1986-03-14 CA CA000504095A patent/CA1285935C/en not_active Expired - Fee Related
- 1986-03-14 EP EP86301896A patent/EP0199451B1/de not_active Expired - Lifetime
- 1986-03-14 DK DK118286A patent/DK166805B1/da not_active IP Right Cessation
- 1986-03-14 DE DE3650492T patent/DE3650492T2/de not_active Expired - Fee Related
- 1986-03-14 AT AT86301896T patent/ATE135011T1/de not_active IP Right Cessation
- 1986-03-14 AU AU54757/86A patent/AU578809B2/en not_active Ceased
- 1986-03-17 JP JP5907386A patent/JPH0723314B2/ja not_active Expired - Lifetime
-
1988
- 1988-12-12 MY MYPI88001437A patent/MY104069A/en unknown
Also Published As
Publication number | Publication date |
---|---|
DK118286A (da) | 1986-09-17 |
DK166805B1 (da) | 1993-07-19 |
EP0199451B1 (de) | 1996-03-06 |
AU578809B2 (en) | 1988-11-03 |
DE3650492D1 (de) | 1996-04-11 |
EP0199451A2 (de) | 1986-10-29 |
AU5475786A (en) | 1986-09-18 |
CA1285935C (en) | 1991-07-09 |
MY104069A (en) | 1993-11-30 |
ATE135011T1 (de) | 1996-03-15 |
JPS61257926A (ja) | 1986-11-15 |
IE860676L (en) | 1986-09-16 |
EP0199451A3 (en) | 1990-09-05 |
IE73219B1 (en) | 1997-05-07 |
JPH0723314B2 (ja) | 1995-03-15 |
DK118286D0 (da) | 1986-03-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |