DE3875769T2 - Therapeutische nukleoside. - Google Patents

Therapeutische nukleoside.

Info

Publication number
DE3875769T2
DE3875769T2 DE8888302922T DE3875769T DE3875769T2 DE 3875769 T2 DE3875769 T2 DE 3875769T2 DE 8888302922 T DE8888302922 T DE 8888302922T DE 3875769 T DE3875769 T DE 3875769T DE 3875769 T2 DE3875769 T2 DE 3875769T2
Authority
DE
Germany
Prior art keywords
therapeutic nucleosides
nucleosides
therapeutic
prophylaxis
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888302922T
Other languages
English (en)
Other versions
DE3875769D1 (de
Inventor
Joel Van Tuttle
Thomas Anthony Krenitsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Application granted granted Critical
Publication of DE3875769D1 publication Critical patent/DE3875769D1/de
Publication of DE3875769T2 publication Critical patent/DE3875769T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8888302922T 1987-04-03 1988-03-31 Therapeutische nukleoside. Expired - Fee Related DE3875769T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878708050A GB8708050D0 (en) 1987-04-03 1987-04-03 Therapeutic nucleosides

Publications (2)

Publication Number Publication Date
DE3875769D1 DE3875769D1 (de) 1992-12-17
DE3875769T2 true DE3875769T2 (de) 1993-04-08

Family

ID=10615214

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888302922T Expired - Fee Related DE3875769T2 (de) 1987-04-03 1988-03-31 Therapeutische nukleoside.

Country Status (12)

Country Link
EP (1) EP0285432B1 (de)
JP (1) JPS63258891A (de)
KR (1) KR880012628A (de)
AT (1) ATE82294T1 (de)
AU (1) AU1412088A (de)
DE (1) DE3875769T2 (de)
DK (1) DK177888A (de)
GB (1) GB8708050D0 (de)
GR (1) GR3006366T3 (de)
HU (1) HU199869B (de)
IL (1) IL85945A0 (de)
ZA (1) ZA882344B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5310732A (en) * 1986-02-03 1994-05-10 The Scripps Research Institute 2-halo-2'-deoxyadenosines in the treatment of rheumatoid arthritis
US5106837A (en) * 1988-03-16 1992-04-21 The Scripps Research Institute Adenosine derivatives with therapeutic activity
IL86381A0 (en) * 1987-05-19 1988-11-15 Nippon Kayaku Kk Oxetanocins and pharmaceutical compositions containing the same
US5214048A (en) * 1987-05-19 1993-05-25 Nippon Kayaku Kabushiki Kaisha Oxetanocins
DE68924319T2 (de) * 1988-03-16 1996-05-15 Scripps Research Inst Als therapeutische mittel verwendbare substituierte adeninderivate.
US4996308A (en) * 1988-03-25 1991-02-26 Merrell Dow Pharmaceuticals Inc. Derivatives with unsaturated substitutions for the 5'-hydroxymethyl group
FI95384C (fi) * 1989-04-06 1996-01-25 Squibb Bristol Myers Co Menetelmä 3'-deoksi-3'-substituoitujen metyylinukleosidien valmistamiseksi ja menetelmässä käytettäviä välituotteita
KR910007655A (ko) * 1989-10-03 1991-05-30 엠. 피. 잭슨 치료용 뉴클레오시드
US5420115A (en) * 1990-09-10 1995-05-30 Burroughs Wellcome Co. Method for the treatment of protoza infections with 21 -deoxy-21 -fluoropurine nucleosides
WO1992011276A1 (en) * 1990-12-18 1992-07-09 Sloan-Kettering Institute For Cancer Research Novel synthesis of 2'-'up' fluorinated 2''-deoxy-arabinofuranosylpurines
CA2119315A1 (en) * 1993-03-18 1994-09-19 Tsujiaki Hata Nucleoside derivatives and anti-herpes composition
JPH06321784A (ja) * 1993-03-18 1994-11-22 Nippon Chemiphar Co Ltd 抗ヒト免疫不全ウイルス剤
US5654286A (en) * 1993-05-12 1997-08-05 Hostetler; Karl Y. Nucleotides for topical treatment of psoriasis, and methods for using same
EP1676853A4 (de) * 2003-10-24 2009-12-23 Yamasa Corp Alpha-1-phosphoryliertes-2-desoxy-2-fluorarabinosid und verfahren zur herstellung von 2 -desoxy-2 -fluor-beta-d-arabinonukleosid
WO2018110643A1 (ja) * 2016-12-14 2018-06-21 ヤマサ醤油株式会社 抗ウイルス活性を示すヌクレオシド誘導体
WO2018181102A1 (ja) * 2017-03-29 2018-10-04 ヤマサ醤油株式会社 ヌクレオシド誘導体又はその塩、及びそれを含む医薬組成物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3658787A (en) * 1969-08-04 1972-04-25 Syntex Corp Halogenated purine nucleosides and derivatives
US4751221A (en) * 1985-10-18 1988-06-14 Sloan-Kettering Institute For Cancer Research 2-fluoro-arabinofuranosyl purine nucleosides

Also Published As

Publication number Publication date
HUT48268A (en) 1989-05-29
IL85945A0 (en) 1988-09-30
GR3006366T3 (de) 1993-06-21
DK177888A (da) 1988-10-04
EP0285432A3 (en) 1990-01-24
EP0285432B1 (de) 1992-11-11
DK177888D0 (da) 1988-03-30
KR880012628A (ko) 1988-11-28
HU199869B (en) 1990-03-28
JPS63258891A (ja) 1988-10-26
DE3875769D1 (de) 1992-12-17
AU1412088A (en) 1988-10-06
ATE82294T1 (de) 1992-11-15
EP0285432A2 (de) 1988-10-05
GB8708050D0 (en) 1987-05-07
ZA882344B (en) 1989-12-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee