DE69324244T2 - Therapeutische nukleoside der 2',3'-dideoxy-3'-fluor -purin reihe - Google Patents

Therapeutische nukleoside der 2',3'-dideoxy-3'-fluor -purin reihe

Info

Publication number
DE69324244T2
DE69324244T2 DE69324244T DE69324244T DE69324244T2 DE 69324244 T2 DE69324244 T2 DE 69324244T2 DE 69324244 T DE69324244 T DE 69324244T DE 69324244 T DE69324244 T DE 69324244T DE 69324244 T2 DE69324244 T2 DE 69324244T2
Authority
DE
Germany
Prior art keywords
dideoxy
pct
purin
fluor
series
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69324244T
Other languages
English (en)
Other versions
DE69324244D1 (de
Inventor
Charlene Burns
George KOSZALKA
Thomas Krenitsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929200149A external-priority patent/GB9200149D0/en
Priority claimed from GB929220317A external-priority patent/GB9220317D0/en
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of DE69324244D1 publication Critical patent/DE69324244D1/de
Application granted granted Critical
Publication of DE69324244T2 publication Critical patent/DE69324244T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE69324244T 1992-01-06 1993-01-05 Therapeutische nukleoside der 2',3'-dideoxy-3'-fluor -purin reihe Expired - Fee Related DE69324244T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929200149A GB9200149D0 (en) 1992-01-06 1992-01-06 Therapeutic nucleosides
GB929220317A GB9220317D0 (en) 1992-09-25 1992-09-25 Therapeutic nucleosides
PCT/GB1993/000004 WO1993014103A1 (en) 1992-01-06 1993-01-05 Therapeutic nucleosides

Publications (2)

Publication Number Publication Date
DE69324244D1 DE69324244D1 (de) 1999-05-06
DE69324244T2 true DE69324244T2 (de) 1999-09-30

Family

ID=26300111

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69324244T Expired - Fee Related DE69324244T2 (de) 1992-01-06 1993-01-05 Therapeutische nukleoside der 2',3'-dideoxy-3'-fluor -purin reihe

Country Status (9)

Country Link
US (1) US5663154A (de)
EP (1) EP0625158B1 (de)
JP (1) JPH07502740A (de)
AT (1) ATE178335T1 (de)
AU (1) AU3170193A (de)
DE (1) DE69324244T2 (de)
DK (1) DK0625158T3 (de)
ES (1) ES2130246T3 (de)
WO (1) WO1993014103A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5654286A (en) * 1993-05-12 1997-08-05 Hostetler; Karl Y. Nucleotides for topical treatment of psoriasis, and methods for using same
ATE236161T1 (de) * 1995-11-01 2003-04-15 Novartis Pharma Gmbh Purinderivate und verfahren zu ihrer herstellung
US6107300A (en) * 1996-03-27 2000-08-22 Dupont Pharmaceuticals Arylamino fused pyrimidines
BR9814367A (pt) * 1997-12-22 2000-10-17 Schering Corp Formas de dosagens de ribavirina sólida administrável oralmente e processo para produzì-las
BR0210594A (pt) * 2001-06-22 2005-11-01 Pharmasset Ltd (beta)-d ou (beta)-l-3-halonucleosìdeo
EP1352910A1 (de) * 2002-04-10 2003-10-15 Grünenthal GmbH Neue Analoga von Nitrobenzylthioinosine
CZ302225B6 (cs) * 2007-07-04 2010-12-29 Univerzita Palackého v Olomouci Substituované 6-anilinopurinové deriváty jako inhibitory cytokinin oxidasy a prípravky obsahující tyto slouceniny
WO2012099630A1 (en) * 2011-01-20 2012-07-26 University Of Rochester Compositions and methods for treating or preventing a retrovirus infection
EP3233860B1 (de) * 2014-12-15 2020-01-29 Univerzita Palackého V Olomouci 6-anilino-9-heterocyclylpurine-derivate zur hemmung von pflanzenstress
US10413488B2 (en) * 2015-12-02 2019-09-17 L'oreal Aerosol oil foam compositions comprising a triglyceride-based oil and surfactant
US11452714B2 (en) 2017-05-23 2022-09-27 Regents Of The University Of Minnesota Antibacterial agents including histidine kinase inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4381344A (en) * 1980-04-25 1983-04-26 Burroughs Wellcome Co. Process for producing deoxyribosides using bacterial phosphorylase
SE8602981D0 (sv) * 1986-07-04 1986-07-04 Astra Laekemedel Ab Novel medicinal use
DD279407A1 (de) * 1986-07-24 1990-06-06 Akad Wissenschaften Ddr Verfahren zur herstellung eines mittels gegen aids
JPS6429390A (en) * 1987-07-24 1989-01-31 Asahi Glass Co Ltd Production of pentofuranoside derivative
JPH01265099A (ja) * 1987-10-08 1989-10-23 Stichting Rega Vzw 抗ｈｉｖ活性をもつ３’，−フルオロプリン−２’，３’−ジデオキシリボシド類
GB8726136D0 (en) * 1987-11-07 1987-12-09 Wellcome Found Therapeutic nucleosides
DD293498A5 (de) * 1989-07-20 1991-09-05 Zi Fuer Molekularbiologie Der Adw,De Verfahren zur herstellung eines mittels fuer die behandlung oder prophylaxe von hepatits-infektionen bei mensch und tier

Also Published As

Publication number Publication date
AU3170193A (en) 1993-08-03
WO1993014103A1 (en) 1993-07-22
DK0625158T3 (da) 1999-10-11
DE69324244D1 (de) 1999-05-06
JPH07502740A (ja) 1995-03-23
EP0625158A1 (de) 1994-11-23
ES2130246T3 (es) 1999-07-01
ATE178335T1 (de) 1999-04-15
US5663154A (en) 1997-09-02
EP0625158B1 (de) 1999-03-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee