JPS6429390A - Production of pentofuranoside derivative - Google Patents
Production of pentofuranoside derivativeInfo
- Publication number
- JPS6429390A JPS6429390A JP62183662A JP18366287A JPS6429390A JP S6429390 A JPS6429390 A JP S6429390A JP 62183662 A JP62183662 A JP 62183662A JP 18366287 A JP18366287 A JP 18366287A JP S6429390 A JPS6429390 A JP S6429390A
- Authority
- JP
- Japan
- Prior art keywords
- group
- derivative
- atom
- protecting group
- fluoropentofuranoside
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Saccharide Compounds (AREA)
Abstract
PURPOSE:To obtain the titled compound useful as medicines, agricultural chemicals, etc., such as metabolic antagonistic substance, RNA synthesis inhibitor, antitumor agent or antiviral agent, by converting a specific group in a deoxy-fluoropentofuranoside derivative into H atom. CONSTITUTION:The -OX group in a 3-deoxy-3-fluoropentofuranoside derivative expressed by formula I [R<1> is halogen, -OZ (Z is alkyl or OH-protecting group) or residue of nucleic acid bases which may have a protecting group; R<2> is OH- protecting group; X is H or eliminative activating group] is converted into H atom to afford the aimed compound expressed by formula II. Furthermore, the -OX group is preferably converted into the H atom by using a reducing agent, such as tributyltin hydride or triphenyltin hydride.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62183662A JPS6429390A (en) | 1987-07-24 | 1987-07-24 | Production of pentofuranoside derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62183662A JPS6429390A (en) | 1987-07-24 | 1987-07-24 | Production of pentofuranoside derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6429390A true JPS6429390A (en) | 1989-01-31 |
Family
ID=16139734
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62183662A Pending JPS6429390A (en) | 1987-07-24 | 1987-07-24 | Production of pentofuranoside derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6429390A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5663154A (en) * | 1992-01-06 | 1997-09-02 | Glaxo Wellcome Inc. | 2',3'-dideoxy-3'-fluoro-purine ribonucleosides |
-
1987
- 1987-07-24 JP JP62183662A patent/JPS6429390A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5663154A (en) * | 1992-01-06 | 1997-09-02 | Glaxo Wellcome Inc. | 2',3'-dideoxy-3'-fluoro-purine ribonucleosides |
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