JPS6429390A - Production of pentofuranoside derivative - Google Patents

Production of pentofuranoside derivative

Info

Publication number
JPS6429390A
JPS6429390A JP62183662A JP18366287A JPS6429390A JP S6429390 A JPS6429390 A JP S6429390A JP 62183662 A JP62183662 A JP 62183662A JP 18366287 A JP18366287 A JP 18366287A JP S6429390 A JPS6429390 A JP S6429390A
Authority
JP
Japan
Prior art keywords
group
derivative
atom
protecting group
fluoropentofuranoside
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62183662A
Other languages
Japanese (ja)
Inventor
Yoshitomi Morisawa
Tomoyuki Asai
Arata Yasuda
Keiichi Uchida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AGC Inc
Original Assignee
Asahi Glass Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Glass Co Ltd filed Critical Asahi Glass Co Ltd
Priority to JP62183662A priority Critical patent/JPS6429390A/en
Publication of JPS6429390A publication Critical patent/JPS6429390A/en
Pending legal-status Critical Current

Links

Classifications

    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Saccharide Compounds (AREA)

Abstract

PURPOSE:To obtain the titled compound useful as medicines, agricultural chemicals, etc., such as metabolic antagonistic substance, RNA synthesis inhibitor, antitumor agent or antiviral agent, by converting a specific group in a deoxy-fluoropentofuranoside derivative into H atom. CONSTITUTION:The -OX group in a 3-deoxy-3-fluoropentofuranoside derivative expressed by formula I [R<1> is halogen, -OZ (Z is alkyl or OH-protecting group) or residue of nucleic acid bases which may have a protecting group; R<2> is OH- protecting group; X is H or eliminative activating group] is converted into H atom to afford the aimed compound expressed by formula II. Furthermore, the -OX group is preferably converted into the H atom by using a reducing agent, such as tributyltin hydride or triphenyltin hydride.
JP62183662A 1987-07-24 1987-07-24 Production of pentofuranoside derivative Pending JPS6429390A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62183662A JPS6429390A (en) 1987-07-24 1987-07-24 Production of pentofuranoside derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62183662A JPS6429390A (en) 1987-07-24 1987-07-24 Production of pentofuranoside derivative

Publications (1)

Publication Number Publication Date
JPS6429390A true JPS6429390A (en) 1989-01-31

Family

ID=16139734

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62183662A Pending JPS6429390A (en) 1987-07-24 1987-07-24 Production of pentofuranoside derivative

Country Status (1)

Country Link
JP (1) JPS6429390A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5663154A (en) * 1992-01-06 1997-09-02 Glaxo Wellcome Inc. 2',3'-dideoxy-3'-fluoro-purine ribonucleosides

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5663154A (en) * 1992-01-06 1997-09-02 Glaxo Wellcome Inc. 2',3'-dideoxy-3'-fluoro-purine ribonucleosides

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