DK92788A - Anvendelse af 3'-deoxy-3'-flourguanosider til fremstilling af laegemidler mod retrovira - Google Patents
Anvendelse af 3'-deoxy-3'-flourguanosider til fremstilling af laegemidler mod retroviraInfo
- Publication number
- DK92788A DK92788A DK092788A DK92788A DK92788A DK 92788 A DK92788 A DK 92788A DK 092788 A DK092788 A DK 092788A DK 92788 A DK92788 A DK 92788A DK 92788 A DK92788 A DK 92788A
- Authority
- DK
- Denmark
- Prior art keywords
- fluoruanosides
- retrovira
- deoxy
- preparation
- medicinal products
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8602981A SE8602981D0 (sv) | 1986-07-04 | 1986-07-04 | Novel medicinal use |
SE8602981 | 1986-07-04 | ||
SE8700316 | 1987-07-02 | ||
PCT/SE1987/000316 WO1988000050A1 (en) | 1986-07-04 | 1987-07-02 | Novel medicinal use of nucleosides |
Publications (3)
Publication Number | Publication Date |
---|---|
DK92788A true DK92788A (da) | 1988-02-23 |
DK92788D0 DK92788D0 (da) | 1988-02-23 |
DK172617B1 DK172617B1 (da) | 1999-03-01 |
Family
ID=20365027
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK198800927A DK172617B1 (da) | 1986-07-04 | 1988-02-23 | Ny medicinsk anvendelse af nukleosider |
Country Status (10)
Country | Link |
---|---|
US (1) | US6358934B1 (da) |
EP (1) | EP0277151B1 (da) |
JP (1) | JP2540576B2 (da) |
AT (1) | ATE68349T1 (da) |
AU (1) | AU598575B2 (da) |
CA (1) | CA1286991C (da) |
DE (1) | DE3773892D1 (da) |
DK (1) | DK172617B1 (da) |
SE (1) | SE8602981D0 (da) |
WO (1) | WO1988000050A1 (da) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6458772B1 (en) | 1909-10-07 | 2002-10-01 | Medivir Ab | Prodrugs |
SE9800452D0 (sv) * | 1998-02-13 | 1998-02-13 | Medivir Ab | Antivirals |
GB8719877D0 (en) * | 1987-08-22 | 1987-09-30 | Wellcome Found | Antiviral compounds |
US5506215A (en) * | 1987-11-03 | 1996-04-09 | Medivir Ab | 1-(3'-fluoro-2',3'-dideoxy-β-D-ribofuranosyl)-5-substituted pyrimidine nucleosides |
GB8726136D0 (en) * | 1987-11-07 | 1987-12-09 | Wellcome Found | Therapeutic nucleosides |
SE8802687D0 (sv) * | 1988-07-20 | 1988-07-20 | Astra Ab | Nucleoside derivatives |
US5157114A (en) * | 1988-08-19 | 1992-10-20 | Burroughs Wellcome Co. | 2',3'-dideoxy-3'-fluoro-5-ethyngluridine |
GB8904855D0 (en) * | 1989-03-03 | 1989-04-12 | Beecham Group Plc | Pharmaceutical treatment |
SE464168B (sv) * | 1989-07-19 | 1991-03-18 | Bo Fredrik Oeberg | Antiviral komposition bestaaende av en 3'-fluoro-2',3'-dideoxynukleosidfoerening och en 2',3'-dideoxynukleosidfoerening (exempelvis azt) |
DD293498A5 (de) * | 1989-07-20 | 1991-09-05 | Zi Fuer Molekularbiologie Der Adw,De | Verfahren zur herstellung eines mittels fuer die behandlung oder prophylaxe von hepatits-infektionen bei mensch und tier |
GB9003543D0 (en) * | 1990-02-16 | 1990-04-11 | Wellcome Found | Therapeutic nucleosides |
DE69324244T2 (de) * | 1992-01-06 | 1999-09-30 | The Wellcome Foundation Ltd., Greenford | Therapeutische nukleoside der 2',3'-dideoxy-3'-fluor -purin reihe |
GB9200150D0 (en) * | 1992-01-06 | 1992-02-26 | Wellcome Found | Therapeutic nucleosides |
US5360714A (en) * | 1992-08-28 | 1994-11-01 | Fox Chase Cancer Center | Hepadnavirus polymerase gene product having RNA-dependent DNA priming and reverse transcriptase activities and methods of measuring the activities thereof |
US5334525A (en) * | 1992-08-28 | 1994-08-02 | Fox Chase Cancer Center | Hepadnavirus polymerase gene product having RNA-dependent DNA priming and reverse transcriptase activities and methods of measuring the activities thereof |
TW374087B (en) * | 1993-05-25 | 1999-11-11 | Univ Yale | L-2',3'-dideoxy nucleotide analogs as anti-hepatitis B(HBV) and anti-HIV agents |
US5627160A (en) * | 1993-05-25 | 1997-05-06 | Yale University | L-2',3'-dideoxy nucleoside analogs as anti-hepatitis B (HBV) and anti-HIV agents |
US5559101A (en) * | 1994-10-24 | 1996-09-24 | Genencor International, Inc. | L-ribofuranosyl nucleosides |
ATE284894T1 (de) * | 1994-10-24 | 2005-01-15 | Genencor Int | L-pyranosyl-nukleoside |
US5869461A (en) * | 1995-03-16 | 1999-02-09 | Yale University | Reducing toxicity of L-nucleosides with D-nucleosides |
TR200002273T2 (tr) * | 1997-08-15 | 2002-06-21 | Medivir Ab | Hepatit B virüsü (HBV) retroviral ters transkriptaz ve DNA polimeraz inhibe edicilerini içeren antiviraller gibi nükleozidlerin analogları. |
ATE314851T1 (de) * | 2002-06-27 | 2006-02-15 | Medivir Ab | Synergistische wechselwirkung von abacavir und alovudin |
EP1610797A1 (en) * | 2003-03-27 | 2006-01-04 | Boehringer Ingelheim International GmbH | Antiviral combination of nevirapine and a further antiretroviral compound |
WO2004087140A1 (en) * | 2003-03-27 | 2004-10-14 | Boehringer Ingelheim International Gmbh | Antiviral combination of a dipyridodiazepinone and a further antiretroviral compound |
WO2004087139A1 (en) | 2003-03-27 | 2004-10-14 | Boehringer Ingelheim International Gmbh | Antiviral combination of tipranavir and a further antiretroviral compound |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3775397A (en) * | 1969-11-12 | 1973-11-27 | Akad Wissenschaften Ddr | Novel cytostatic 2',3'-dideoxy-3'-fluoropyrimidine-nucleosides |
DD139793A1 (de) * | 1978-11-06 | 1980-01-23 | Waltraud Braun | Mittel gegen psoriasis |
DD158903A1 (de) * | 1981-05-18 | 1983-02-09 | Gotthard Kowollik | Verfahren zur herstellung von 3'-fluor-2',3'-didesoxyadenosin |
DD209197A1 (de) * | 1981-07-21 | 1984-04-25 | Akad Wissenschaften Ddr | Verfahren zur herstellung von 3'-fluor-2',3'-didesoxyguanosin |
US4724232A (en) | 1985-03-16 | 1988-02-09 | Burroughs Wellcome Co. | Treatment of human viral infections |
JPH07116042B2 (ja) * | 1985-05-15 | 1995-12-13 | ザ ウエルカム フアウンデ−シヨン リミテツド | ヌクレオシド化合物 |
EP0258412A1 (en) | 1986-02-20 | 1988-03-09 | GREER, Sheldon B. | Composition for and method of treating aids and certain related diseases |
-
1986
- 1986-07-04 SE SE8602981A patent/SE8602981D0/xx unknown
-
1987
- 1987-07-02 WO PCT/SE1987/000316 patent/WO1988000050A1/en active IP Right Grant
- 1987-07-02 AT AT87904641T patent/ATE68349T1/de not_active IP Right Cessation
- 1987-07-02 JP JP62504153A patent/JP2540576B2/ja not_active Expired - Lifetime
- 1987-07-02 AU AU77005/87A patent/AU598575B2/en not_active Expired
- 1987-07-02 DE DE8787904641T patent/DE3773892D1/de not_active Expired - Lifetime
- 1987-07-02 EP EP87904641A patent/EP0277151B1/en not_active Expired - Lifetime
- 1987-07-03 CA CA000541194A patent/CA1286991C/en not_active Expired - Lifetime
-
1988
- 1988-02-23 DK DK198800927A patent/DK172617B1/da not_active IP Right Cessation
-
1989
- 1989-03-07 US US07/319,840 patent/US6358934B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US6358934B1 (en) | 2002-03-19 |
JPH01500193A (ja) | 1989-01-26 |
CA1286991C (en) | 1991-07-30 |
AU7700587A (en) | 1988-01-29 |
DE3773892D1 (de) | 1991-11-21 |
AU598575B2 (en) | 1990-06-28 |
WO1988000050A1 (en) | 1988-01-14 |
SE8602981D0 (sv) | 1986-07-04 |
DK92788D0 (da) | 1988-02-23 |
JP2540576B2 (ja) | 1996-10-02 |
ATE68349T1 (de) | 1991-11-15 |
EP0277151A1 (en) | 1988-08-10 |
EP0277151B1 (en) | 1991-10-16 |
DK172617B1 (da) | 1999-03-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PUP | Patent expired |