HUP9900945A2 - Nukleozidanalógok herpes simplex vírus fertőzések kombinációs terápiájában - Google Patents

Nukleozidanalógok herpes simplex vírus fertőzések kombinációs terápiájában

Info

Publication number
HUP9900945A2
HUP9900945A2 HU9900945A HUP9900945A HUP9900945A2 HU P9900945 A2 HUP9900945 A2 HU P9900945A2 HU 9900945 A HU9900945 A HU 9900945A HU P9900945 A HUP9900945 A HU P9900945A HU P9900945 A2 HUP9900945 A2 HU P9900945A2
Authority
HU
Hungary
Prior art keywords
herpes simplex
nucleoside analogs
simplex virus
simplex infections
prevention
Prior art date
Application number
HU9900945A
Other languages
English (en)
Inventor
Malcolm Richard Boyd
Original Assignee
Smithkline Beecham Plc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10787583&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP9900945(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Plc. filed Critical Smithkline Beecham Plc.
Publication of HUP9900945A2 publication Critical patent/HUP9900945A2/hu
Publication of HUP9900945A3 publication Critical patent/HUP9900945A3/hu
Publication of HU226793B1 publication Critical patent/HU226793B1/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

A találmány tárgya herpes simplex vírűs ellen hatékőnynűkleőzidanalógők felhasználása herpessimplexvírűs-fertőzésekkezelésére és/vagy megelőzésére szőlgáló gyógyászati készítményekelőállításáhőz. A találmány szerinti gyógyászati készítmények egyherpes simplex vírűs ellen hatékőny nűkleőzidanalógőt és egyimműnszűppresszánst tartalmaznak, kőmbinált készítmény főrmájában,egyidejű, elkülönített, vagy egymást követő felhasználásra. Atalálmány tővábbá herpessimplexvírűs-fertőzések kezelésére és/vagymegelőzésére szőlgáló eljárásra is vőnatkőzik, amelynek sőrán a fentigyógyászati készítményt adagőlják embernek vagy állatnak. ŕ
HU9900945A 1996-01-26 1997-01-24 Use of nucleoside analogs and cyclosporin a in the manufacture of combined preparation against herpes simplex virus infections HU226793B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9601544.1A GB9601544D0 (en) 1996-01-26 1996-01-26 Pharmaceuticals
PCT/GB1997/000226 WO1997026882A1 (en) 1996-01-26 1997-01-24 Nucleoside analogs in combination therapy of herpes simplex infections

Publications (3)

Publication Number Publication Date
HUP9900945A2 true HUP9900945A2 (hu) 1999-07-28
HUP9900945A3 HUP9900945A3 (en) 2001-02-28
HU226793B1 HU226793B1 (en) 2009-10-28

Family

ID=10787583

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9900945A HU226793B1 (en) 1996-01-26 1997-01-24 Use of nucleoside analogs and cyclosporin a in the manufacture of combined preparation against herpes simplex virus infections

Country Status (26)

Country Link
US (5) US6514980B1 (hu)
EP (1) EP0876146B1 (hu)
JP (1) JP2000507211A (hu)
KR (1) KR19990081966A (hu)
CN (1) CN1133433C (hu)
AR (1) AR005551A1 (hu)
AT (1) ATE238796T1 (hu)
AU (1) AU713202B2 (hu)
BR (1) BR9707304A (hu)
CY (1) CY2421B1 (hu)
CZ (1) CZ297841B6 (hu)
DE (1) DE69721484T2 (hu)
DK (1) DK0876146T3 (hu)
ES (1) ES2199339T3 (hu)
GB (1) GB9601544D0 (hu)
HK (1) HK1016475A1 (hu)
HU (1) HU226793B1 (hu)
IL (1) IL125075A (hu)
NO (1) NO316355B1 (hu)
NZ (1) NZ326839A (hu)
PL (1) PL187076B1 (hu)
PT (1) PT876146E (hu)
TR (1) TR199801439T2 (hu)
TW (1) TW493985B (hu)
WO (1) WO1997026882A1 (hu)
ZA (1) ZA97608B (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW438585B (en) 1995-02-06 2001-06-07 Astra Ab Pharmaceutical compositions for topical administration for prophylaxis and/or treatment of herpesvirus infections
GB9601544D0 (en) * 1996-01-26 1996-03-27 Smithkline Beecham Plc Pharmaceuticals
US7591945B2 (en) * 2003-02-07 2009-09-22 Gambro Lundia Ab Support device for containers in extracorporeal blood treatment machines
JP2008536822A (ja) * 2005-03-25 2008-09-11 アルト ソリューションズ インコーポレーテッド テロメラーゼ陽性細胞におけるテロメア長の調節および癌治療
WO2006125166A2 (en) * 2005-05-18 2006-11-23 Alt Solutions, Inc. Pharmacological modulation of telomere length in cancer cells for prevention and treatment of cancer
WO2011035120A2 (en) * 2009-09-17 2011-03-24 Gk Ventures, L.L.C. Therapeutic composition to treat lesions caused by herpes simplex virus
GB201907305D0 (en) * 2019-05-23 2019-07-10 Douglas Pharmaceuticals Ltd Treatment of conditions
CN112704154A (zh) * 2020-12-24 2021-04-27 中国人民解放军66399部队 一种用于治疗宠物猫疱疹病毒的营养膏

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3317384A (en) * 1964-06-08 1967-05-02 Upjohn Co Treatment of topical viral infections with glucocorticoids and nucleosides
US3322627A (en) * 1964-09-03 1967-05-30 Merck & Co Inc Method of treating herpes simplex infections with 5-methylamino-2'-deoxyuridine, and compositions therefor
GB9001886D0 (en) * 1990-01-26 1990-03-28 Beecham Group Plc Pharmaceutical formulation
GB9015051D0 (en) * 1990-07-07 1990-08-29 Beecham Group Plc Pharmaceutical treatment
ES2096215T3 (es) 1992-10-01 1997-03-01 Wellcome Found Tucaresol como agente inmunopotenciador.
GB9426021D0 (en) 1994-12-22 1995-02-22 Smithkline Beecham Plc Pharmaceuticals
TW438585B (en) * 1995-02-06 2001-06-07 Astra Ab Pharmaceutical compositions for topical administration for prophylaxis and/or treatment of herpesvirus infections
GB9601544D0 (en) * 1996-01-26 1996-03-27 Smithkline Beecham Plc Pharmaceuticals
US6136835A (en) * 1999-05-17 2000-10-24 The Procter & Gamble Company Methods of treatment for viral infections

Also Published As

Publication number Publication date
US20050222016A1 (en) 2005-10-06
TW493985B (en) 2002-07-11
ATE238796T1 (de) 2003-05-15
BR9707304A (pt) 1999-07-20
ZA97608B (en) 1998-07-24
US20080287389A1 (en) 2008-11-20
CN1133433C (zh) 2004-01-07
JP2000507211A (ja) 2000-06-13
CZ234098A3 (cs) 1999-02-17
AU713202B2 (en) 1999-11-25
NZ326839A (en) 2001-02-23
GB9601544D0 (en) 1996-03-27
KR19990081966A (ko) 1999-11-15
NO983402D0 (no) 1998-07-23
IL125075A (en) 2003-02-12
AR005551A1 (es) 1999-06-23
EP0876146A1 (en) 1998-11-11
US20040185433A1 (en) 2004-09-23
PL187076B1 (pl) 2004-05-31
HU226793B1 (en) 2009-10-28
PT876146E (pt) 2003-09-30
NO316355B1 (no) 2004-01-19
CY2421B1 (en) 2004-11-12
US20100323952A1 (en) 2010-12-23
CZ297841B6 (cs) 2007-04-11
HUP9900945A3 (en) 2001-02-28
AU1550697A (en) 1997-08-20
ES2199339T3 (es) 2004-02-16
DE69721484T2 (de) 2004-02-26
IL125075A0 (en) 1999-01-26
US6514980B1 (en) 2003-02-04
PL327917A1 (en) 1999-01-04
DE69721484D1 (de) 2003-06-05
WO1997026882A1 (en) 1997-07-31
EP0876146B1 (en) 2003-05-02
NO983402L (no) 1998-07-23
TR199801439T2 (xx) 1998-10-21
CN1209748A (zh) 1999-03-03
DK0876146T3 (da) 2003-08-11
HK1016475A1 (en) 1999-11-05

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Legal Events

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MM4A Lapse of definitive patent protection due to non-payment of fees