DK163482A - Mellemprodukt til fremstilling af alfa-aminopenicillinestere - Google Patents

Mellemprodukt til fremstilling af alfa-aminopenicillinestere Download PDF

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Publication number
DK163482A
DK163482A DK163482A DK163482A DK163482A DK 163482 A DK163482 A DK 163482A DK 163482 A DK163482 A DK 163482A DK 163482 A DK163482 A DK 163482A DK 163482 A DK163482 A DK 163482A
Authority
DK
Denmark
Prior art keywords
aminopenicillin
alfa
esters
preparation
aminopenicillin esters
Prior art date
Application number
DK163482A
Other languages
English (en)
Other versions
DK158519C (da
DK158519B (da
Inventor
Bertil A Ekstroem
Berndt O Sjoeberg
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE7012688A external-priority patent/SE374747B/xx
Priority claimed from SE7015720A external-priority patent/SE380806B/xx
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of DK163482A publication Critical patent/DK163482A/da
Publication of DK158519B publication Critical patent/DK158519B/da
Application granted granted Critical
Publication of DK158519C publication Critical patent/DK158519C/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
DK163482A 1970-09-17 1982-04-07 Benzylpenicillinderivat til anvendelse som udgangsmateriale ved fremgangsmaaden til fremstilling af alfa-aminopenicillinestere DK158519C (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
SE1268870 1970-09-17
SE7012688A SE374747B (da) 1970-09-17 1970-09-17
SE7015720A SE380806B (sv) 1970-11-20 1970-11-20 Forfarande for framstellning av nya estrar av alfa-aminopenicilliner
SE1572070 1970-11-20
DK453871A DK132759C (da) 1970-09-17 1971-09-16 Analogifremgangsmade til fremstilling af alfa-aminopenicillinestere eller syreadditionssalte deraf eller de tilsvarende optiske antipoder
DK453871 1971-09-16

Publications (3)

Publication Number Publication Date
DK163482A true DK163482A (da) 1982-04-07
DK158519B DK158519B (da) 1990-05-28
DK158519C DK158519C (da) 1990-11-05

Family

ID=26655897

Family Applications (6)

Application Number Title Priority Date Filing Date
DK453871A DK132759C (da) 1970-09-17 1971-09-16 Analogifremgangsmade til fremstilling af alfa-aminopenicillinestere eller syreadditionssalte deraf eller de tilsvarende optiske antipoder
DK509774A DK509774A (da) 1970-09-17 1974-09-27
DK509674A DK150200C (da) 1970-09-17 1974-09-27 6-aminopenicillansyreester til anvendelse ved fremstilling af et n-acylderivat af en 6-aminopenicillansyreester
DK375975A DK375975A (da) 1970-09-17 1975-08-20
DK133380A DK150201C (da) 1970-09-17 1980-03-27 Alfa-azido-n-acyl-6-aminopenicillansyreester til anvendelse ved fremstilling af den tilsvarende alfa-aminoforbindelse
DK163482A DK158519C (da) 1970-09-17 1982-04-07 Benzylpenicillinderivat til anvendelse som udgangsmateriale ved fremgangsmaaden til fremstilling af alfa-aminopenicillinestere

Family Applications Before (5)

Application Number Title Priority Date Filing Date
DK453871A DK132759C (da) 1970-09-17 1971-09-16 Analogifremgangsmade til fremstilling af alfa-aminopenicillinestere eller syreadditionssalte deraf eller de tilsvarende optiske antipoder
DK509774A DK509774A (da) 1970-09-17 1974-09-27
DK509674A DK150200C (da) 1970-09-17 1974-09-27 6-aminopenicillansyreester til anvendelse ved fremstilling af et n-acylderivat af en 6-aminopenicillansyreester
DK375975A DK375975A (da) 1970-09-17 1975-08-20
DK133380A DK150201C (da) 1970-09-17 1980-03-27 Alfa-azido-n-acyl-6-aminopenicillansyreester til anvendelse ved fremstilling af den tilsvarende alfa-aminoforbindelse

Country Status (21)

Country Link
US (2) US3873521A (da)
JP (2) JPS5317597B1 (da)
AR (2) AR201730A1 (da)
AT (2) AT311557B (da)
BE (1) BE772723A (da)
BR (1) BR7106116D0 (da)
CA (2) CA960211A (da)
CH (5) CH583239A5 (da)
CS (2) CS187312B2 (da)
DD (1) DD94815A5 (da)
DK (6) DK132759C (da)
ES (3) ES395145A1 (da)
FI (4) FI55203C (da)
FR (1) FR2106578B1 (da)
GB (1) GB1363506A (da)
HU (1) HU165868B (da)
IE (1) IE35642B1 (da)
IT (1) IT1049876B (da)
NL (3) NL164860C (da)
NO (4) NO140931C (da)
SU (2) SU553936A3 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1425933A (en) * 1972-03-13 1976-02-25 Astra Laekemedel Ab Cephalosporins
GB1426869A (en) * 1972-03-13 1976-03-03 Astra Laekemedel Ab Penicillins
US4089963A (en) * 1972-03-13 1978-05-16 Astra Pharmaceutical Products, Inc. Esters of amidinopenicillanic acids, pharmaceutical preparations and method for treating infectious diseases
GB1437088A (en) * 1972-05-25 1976-05-26 Beecham Group Ltd Esters of penicillins and cephalosporins
NL7401782A (da) * 1973-02-14 1974-08-16
GB1550359A (en) * 1975-08-07 1979-08-15 Beecham Group Ltd Antibiotic compositions for oral administration
US4247461A (en) * 1979-11-16 1981-01-27 Bristol-Myers Company Esterification process using methoxymethyl-P-toluenesulfonate
US4340539A (en) * 1980-01-21 1982-07-20 Bristol-Myers Company Derivatives of 6-bromo penicillanic acid
CA1212105A (en) 1980-04-30 1986-09-30 Shoji Ikeda Ampicillin esters and production thereof
FR2482587A1 (fr) * 1980-05-14 1981-11-20 Poudres & Explosifs Ste Nale Procede de synthese de chloroformiates a-chlores et nouveaux chloroformiates a-chlores
US4321253A (en) * 1980-08-22 1982-03-23 Beatty Morgan L Suspension of microencapsulated bacampicillin acid addition salt for oral, especially pediatric, administration
US4479947A (en) * 1981-07-13 1984-10-30 Merck & Co., Inc. Oral absorption enhancement of carboxylic acid pharmaceuticals using (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl ester group
CA1202617A (en) * 1982-03-19 1986-04-01 Norman B. Jones Bacampicillin napsylate
SE454879B (sv) * 1982-06-29 1988-06-06 Astra Laekemedel Ab Alfa-bromodietylkarbonat samt dess anvendning som mellanprodukt vid framstellning av penicillin g
IT1190897B (it) * 1982-06-29 1988-02-24 Opos Biochimica Srl Procedimento per la preparazione dell'estere 1-etossicarbonilossietilico dell'acido 6-(d(-)-alfa aminoalfa fenilacetamido)-penicillanico
GB2123821B (en) * 1982-06-29 1987-04-23 Astra Laekemedel Ab At-halogeno diethyl carbonates and their use in the preparation of antibiotics
FR2532933B1 (fr) * 1982-06-29 1987-11-13 Astra Laekemedel Ab Perfectionnements apportes a la preparation d'antibiotiques
JPS5927900A (ja) * 1982-08-09 1984-02-14 Wakunaga Seiyaku Kk 固定化オリゴヌクレオチド
US4606865A (en) * 1982-09-20 1986-08-19 Astra Lakemedel Aktiebolag Methods for the preparation of α-bromodiethylcarbonate
DK149079C (da) * 1982-10-06 1986-06-23 Novo Industri As Fremgangsmaade til fremstilling af et immobiliseret enzympraeparat
IL67177A (en) * 1982-11-04 1985-08-30 Orvet Bv 1-bromoethyl ethyl carbonate,methods for its preparation and 1-bromoethylchloroformate and 1-bromoethylbromoformate obtained as intermediates
IL67637A0 (en) * 1983-01-07 1983-05-15 Orvet Bv Preparation of 1'-ethoxycarbonyl-oxyethyl esters of penicillins and novel intermediates
IL67445A (en) * 1982-12-09 1985-11-29 Teva Pharma Ethoxycarbonyloxy ethyl esters of non-steroidal anti-inflammatory carboxylic acids
FR2551058B1 (fr) * 1983-08-26 1986-09-26 Poudres & Explosifs Ste Nale Procede de preparation de chloroformiates a-chlores
SE8405611D0 (sv) * 1984-11-09 1984-11-09 Astra Laekemedel Ab Process for stabilization of bacampicillin hydrochloride
US4855455A (en) * 1988-01-22 1989-08-08 W. R. Grace & Co.-Conn. Preparation of amino acid derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1021654A (fr) * 1949-07-07 1953-02-23 Lphivens Kemiske Fabrik Ved A Procédé de production d'éthers-sels aminés de pénicilline et de composés qui s'y rattachent
GB1241844A (en) * 1968-08-23 1971-08-04 Beecham Group Ltd Penicillins
US3660575A (en) * 1968-09-26 1972-05-02 Leo Pharm Prod Ltd Esters of alpha-aminobenzylpenicillin in dosage unit form
US3697507A (en) * 1968-09-26 1972-10-10 Leo Pharm Prod Ltd Esters of {60 -aminobenzylpenicillin

Also Published As

Publication number Publication date
BR7106116D0 (pt) 1973-03-20
FI59600B (fi) 1981-05-29
DK150201B (da) 1987-01-05
IE35642B1 (en) 1976-04-14
DK150200B (da) 1987-01-05
NO784144L (no) 1972-03-20
DK375975A (da) 1975-08-20
NO142670B (no) 1980-06-16
DK158519C (da) 1990-11-05
NL164860C (nl) 1981-02-16
DK132759B (da) 1976-02-02
CH583239A5 (da) 1976-12-31
JPS5537996B2 (da) 1980-10-01
CH613207A5 (da) 1979-09-14
NL171160C (nl) 1983-02-16
GB1363506A (en) 1974-08-14
NO140931C (no) 1979-12-12
US3873521A (en) 1975-03-25
FR2106578A1 (da) 1972-05-05
CH589654A5 (da) 1977-07-15
DK150201C (da) 1987-07-06
CS187316B2 (da) 1979-01-31
FI55203C (fi) 1979-06-11
DK133380A (da) 1980-03-27
FR2106578B1 (da) 1975-06-06
CH577513A5 (da) 1976-07-15
DD94815A5 (da) 1973-01-05
SU1153830A3 (ru) 1985-04-30
DE2144457A1 (da) 1972-03-30
DK509774A (da) 1975-05-26
CA960211A (en) 1974-12-31
FI773032A (da) 1977-10-13
CH602745A5 (da) 1978-07-31
IT1049876B (it) 1981-02-10
IE35642L (en) 1972-03-17
DK509674A (da) 1975-06-02
DE2144457B2 (de) 1977-05-05
NL8001563A (nl) 1980-06-30
ES395145A1 (es) 1974-11-16
FI59103B (fi) 1981-02-27
NO140931B (no) 1979-09-03
ES433637A1 (es) 1976-11-16
CS187312B2 (en) 1979-01-31
FI59600C (fi) 1981-09-10
HU165868B (da) 1974-12-28
NO744606L (da) 1972-03-20
AT311557B (de) 1973-11-26
JPS5317597B1 (da) 1978-06-09
JPS5136491A (da) 1976-03-27
AT309681B (de) 1973-08-27
FI57951B (fi) 1980-07-31
FI381474A (da) 1974-12-31
NL7112789A (da) 1972-03-21
NO142670C (no) 1980-09-24
AR210991A1 (es) 1977-10-14
SU553936A3 (ru) 1977-04-05
NL171160B (nl) 1982-09-16
NL7801086A (nl) 1978-05-31
FI55203B (fi) 1979-02-28
DK132759C (da) 1976-07-05
US3939270A (en) 1976-02-17
DK158519B (da) 1990-05-28
AR201730A1 (es) 1975-04-15
FI791386A (fi) 1979-04-27
FI57951C (fi) 1980-11-10
NO142671C (no) 1980-09-24
BE772723A (fr) 1972-03-17
DK150200C (da) 1987-07-06
NO140930C (no) 1979-12-12
CA1008447A (en) 1977-04-12
ES401745A1 (es) 1976-05-16
NO140930B (no) 1979-09-03
NO142671B (no) 1980-06-16
FI59103C (fi) 1981-06-10

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