DK162889C - Substituerede hexahydrobenzindenoazepiner, fremgangsmaader til fremstilling af saadanne forbindelser, farmaceutiske praeparater indeholdende forbindelserne, anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater samt fremgangsmaade til fremstilling af saadanne farmaceutiske praeparater - Google Patents

Substituerede hexahydrobenzindenoazepiner, fremgangsmaader til fremstilling af saadanne forbindelser, farmaceutiske praeparater indeholdende forbindelserne, anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater samt fremgangsmaade til fremstilling af saadanne farmaceutiske praeparater

Info

Publication number
DK162889C
DK162889C DK009390A DK9390A DK162889C DK 162889 C DK162889 C DK 162889C DK 009390 A DK009390 A DK 009390A DK 9390 A DK9390 A DK 9390A DK 162889 C DK162889 C DK 162889C
Authority
DK
Denmark
Prior art keywords
frames
preparation
hexahydrodaminededozeozepine
undertakings
preparations
Prior art date
Application number
DK009390A
Other languages
Danish (da)
English (en)
Other versions
DK9390A (da
DK162889B (da
DK9390D0 (da
Inventor
Joel Gilbert Berger
Wei Kong Chang
Elijah Herman Gold
John Welch Clader
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of DK9390D0 publication Critical patent/DK9390D0/da
Publication of DK9390A publication Critical patent/DK9390A/da
Publication of DK162889B publication Critical patent/DK162889B/da
Application granted granted Critical
Publication of DK162889C publication Critical patent/DK162889C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/32Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Electroluminescent Light Sources (AREA)
  • Luminescent Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK009390A 1987-07-15 1990-01-12 Substituerede hexahydrobenzindenoazepiner, fremgangsmaader til fremstilling af saadanne forbindelser, farmaceutiske praeparater indeholdende forbindelserne, anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater samt fremgangsmaade til fremstilling af saadanne farmaceutiske praeparater DK162889C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/US1987/001636 WO1989000561A1 (fr) 1987-07-15 1987-07-15 Benzazepines fusionnees
US8701636 1987-07-15
EP87110253A EP0299101B1 (fr) 1987-07-15 1987-07-16 Benzazépines condensées
EP87110253 1987-07-16

Publications (4)

Publication Number Publication Date
DK9390D0 DK9390D0 (da) 1990-01-12
DK9390A DK9390A (da) 1990-03-12
DK162889B DK162889B (da) 1991-12-23
DK162889C true DK162889C (da) 1992-05-11

Family

ID=26108265

Family Applications (1)

Application Number Title Priority Date Filing Date
DK009390A DK162889C (da) 1987-07-15 1990-01-12 Substituerede hexahydrobenzindenoazepiner, fremgangsmaader til fremstilling af saadanne forbindelser, farmaceutiske praeparater indeholdende forbindelserne, anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater samt fremgangsmaade til fremstilling af saadanne farmaceutiske praeparater

Country Status (13)

Country Link
EP (2) EP0363353B1 (fr)
JP (1) JPH0678317B2 (fr)
AT (1) ATE78467T1 (fr)
AU (1) AU617651B2 (fr)
DE (1) DE3780649T2 (fr)
DK (1) DK162889C (fr)
ES (1) ES2043623T3 (fr)
FI (1) FI93212C (fr)
GR (1) GR3006671T3 (fr)
HU (1) HU203537B (fr)
NO (1) NO177264C (fr)
WO (1) WO1989000561A1 (fr)
ZA (1) ZA875183B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4973586A (en) 1986-01-16 1990-11-27 Schering Corporation Fused benzazepines, compositions of, and medical use thereof
PL168408B1 (pl) * 1989-08-03 1996-02-29 Smithkline Beecham Biolog Sposób wytwarzania stransformowanego mikroorganizmu PL
CA2075181C (fr) * 1990-02-02 1997-12-09 Theodros Asberom 2,3,4,5-tetrahydro-1h-3-benzazepine-7-ols pontes en 4,5
JPH07137816A (ja) * 1993-11-15 1995-05-30 Tokai Univ 地下空洞内貯蔵装置
CN1688584A (zh) * 2002-08-29 2005-10-26 先灵公司 治疗肥胖和中枢神经系统疾病的选择性d1/d5受体拮抗剂
MXPA05012572A (es) * 2003-05-22 2006-02-08 Schering Corp Derivado de 5-h-benzo[d]naft[2,1-b]azepina como antagonistas selectivos del receptor d1/d5 para el tratamiento de la obesidad y trastornos del sistema nervioso central.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3393192A (en) * 1965-04-26 1968-07-16 Schering Corp Novel benzazepines
CH481110A (de) * 1967-02-17 1969-11-15 Geigy Ag J R Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
US4680298A (en) * 1983-05-31 1987-07-14 Schering Corporation Tricyclic anti-allergy and use as anti-inflammatory agents
EP0254737B1 (fr) * 1986-01-16 1990-07-25 Schering Corporation Benzazepines fondues

Also Published As

Publication number Publication date
AU617651B2 (en) 1991-12-05
ZA875183B (en) 1988-04-08
WO1989000561A1 (fr) 1989-01-26
JPH0678317B2 (ja) 1994-10-05
DK9390A (da) 1990-03-12
FI93212B (fi) 1994-11-30
DE3780649T2 (de) 1992-12-10
NO900186D0 (no) 1990-01-12
JPH02504629A (ja) 1990-12-27
DK162889B (da) 1991-12-23
EP0363353B1 (fr) 1992-07-22
ES2043623T3 (es) 1994-01-01
NO177264B (no) 1995-05-08
NO177264C (no) 1995-08-16
ATE78467T1 (de) 1992-08-15
DE3780649D1 (de) 1992-08-27
FI900175A0 (fi) 1990-01-12
DK9390D0 (da) 1990-01-12
GR3006671T3 (fr) 1993-06-30
EP0299101A1 (fr) 1989-01-18
HU203537B (en) 1991-08-28
FI93212C (fi) 1995-03-10
EP0299101B1 (fr) 1992-09-23
NO900186L (no) 1990-01-12
EP0363353A1 (fr) 1990-04-18
AU8037887A (en) 1989-02-13

Similar Documents

Publication Publication Date Title
FI20000353A (fi) 3,4,4-trisubstituoidun piperidinyyli-N-alkyylikarboksylaatin valmistus ja välituotteet
BR9407910A (pt) Composto composiçao farmacêutica uso do composto processo de tratamento de distúrbios no sistema nervoso central e processo de preparaçao do composto
DE68927697D1 (de) Fluor substituierte Benzocycloheptapyridine, Zusammensetzungen und Verfahren zur Verwendung derselben als antihistaminische Verbindungen
DK94783A (da) Fremgangsmaade til fremstilling af kvaternaere 6,11-dihydro-dibenzo-(b,e)-thiepin-11-n-alkyl-norscopinethere og mellemprodukter herfor
WO1987004430A3 (fr) Benzazepines fondues
ATE293595T1 (de) Thyroidhormon-analoga und verfahren zu ihrer herstellung
SE8600174D0 (sv) Nytt forfarande for framstellning av n-(2-pyrimidinyl)-piperazinylalkylazaspiroalkandioner
PT80752B (pt) Processo de preparacao de composicoes farmaceuticas solidas contendo di-hidropiridinas
DK0638068T3 (da) Fremgangsmåde til fremstilling af (S)-3-amino-1-substitueret-pyrrolidiner
DK162889C (da) Substituerede hexahydrobenzindenoazepiner, fremgangsmaader til fremstilling af saadanne forbindelser, farmaceutiske praeparater indeholdende forbindelserne, anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater samt fremgangsmaade til fremstilling af saadanne farmaceutiske praeparater
DK0536197T3 (da) Ren, krystallinsk form af rifapentine
DK0422566T3 (da) Fremgangsmåde til fremstilling af 3-(L-pyroglutamyl)-L-thiazolidin-4-carboxylsyre og derivater deraf
DE59105224D1 (de) Verfahren zur Herstellung von N-substituierten Pyrrolidonen.
NO930205L (no) Benzimidazoler, legemidler inneholdende disse, og fremgangsmaate for deres fremstilling
DK0906255T3 (da) Fremgangsmåde til fremstilling af enantiomert ren azetidin-2-carboxylsyre
DK0840724T3 (da) Fremgangsmåde til fremstilling af enantiomerisk ren azetidin-2-caboxylsyre
DE69231883D1 (de) 4-(1,1-Dialkoxycarbonyl-Alkyl)Azetidin-2-on-Derivate zur Herstellung von 4-(1-Carboxy-Alkyl)Azetidin-2-on-Derivaten
DK0635490T3 (da) Fremgangsmåde til fremstilling af N-ethylcarbazol
DE69802636T2 (de) Verbessertes Verfahren zur Herstellung von unsymmetrischen 4,6-bis(aryloxy)pyrimidinverbindungen
SE8400118D0 (sv) Substituted carboxy-thiazolo(3,2-a)pyrimidine derivatives and process for their preparation
DE59105920D1 (de) Verfahren zur Herstellung von 5-Hydroxy-3,4,5,6-tetrahydro-pyrimidin-Derivaten.
DK0761657T3 (da) Fremgangsmåde til fremstilling af benzylsubstituerede rhodaninderivater
DE58906998D1 (de) Verfahren zur Herstellung von 4,5,6-Trichlorpyrimidin.
DK0582977T3 (da) Fremgangsmåde til fremstilling af 1,3-dialkyl-5-hydroxyoxindoler og etherderivater deraf
DK0800392T3 (da) Farmaceutiske præparater med indhold af nifedipin samt fremgangsmåde til fremstilling deraf