DK0422566T3 - Fremgangsmåde til fremstilling af 3-(L-pyroglutamyl)-L-thiazolidin-4-carboxylsyre og derivater deraf - Google Patents
Fremgangsmåde til fremstilling af 3-(L-pyroglutamyl)-L-thiazolidin-4-carboxylsyre og derivater derafInfo
- Publication number
- DK0422566T3 DK0422566T3 DK90119271.6T DK90119271T DK0422566T3 DK 0422566 T3 DK0422566 T3 DK 0422566T3 DK 90119271 T DK90119271 T DK 90119271T DK 0422566 T3 DK0422566 T3 DK 0422566T3
- Authority
- DK
- Denmark
- Prior art keywords
- derivatives
- thiazolidine
- carboxylic acid
- pyroglutamyl
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22003A IT1239029B (it) | 1989-10-12 | 1989-10-12 | Processo per la preparazione dell'acido 3-(l-piroglutamil)-l- tiazolidin-4-carbossilico e suoi derivati. |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0422566T3 true DK0422566T3 (da) | 1995-06-26 |
Family
ID=11190043
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK90119271.6T DK0422566T3 (da) | 1989-10-12 | 1990-10-08 | Fremgangsmåde til fremstilling af 3-(L-pyroglutamyl)-L-thiazolidin-4-carboxylsyre og derivater deraf |
Country Status (18)
Country | Link |
---|---|
US (1) | US5110936A (da) |
EP (1) | EP0422566B1 (da) |
JP (1) | JP2813450B2 (da) |
KR (1) | KR100195895B1 (da) |
AT (1) | ATE121420T1 (da) |
AU (1) | AU644379B2 (da) |
CA (1) | CA2027341C (da) |
DE (2) | DE422566T1 (da) |
DK (1) | DK0422566T3 (da) |
ES (1) | ES2028766T3 (da) |
FI (1) | FI95271C (da) |
GR (1) | GR910300072T1 (da) |
HU (1) | HU210213B (da) |
IE (1) | IE67047B1 (da) |
IL (1) | IL95949A (da) |
IT (1) | IT1239029B (da) |
NO (1) | NO178028C (da) |
ZA (1) | ZA908097B (da) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1230706B (it) * | 1989-02-10 | 1991-10-29 | Poli Ind Chimica Spa | Derivati dell'acido 3 piroglutamoil tiazolidin 4 carbossilico e loro proprieta' farmacologiche. |
IT1237998B (it) * | 1990-01-23 | 1993-06-21 | Poli Ind Chimica Spa | Acido 3-l-(5-tioxo-l-prolil)tiazolidin-4-carbossilico e derivati, loro preparazione e composizioni farmaceutiche che li contengono |
IT1270017B (it) * | 1994-09-27 | 1997-04-16 | Poli Ind Chimica Spa | "sintesi quantitativa dell'acido 3-(l-piroglutamil)-l-tiazolidin-4- carbossilico e suoi derivati" |
AU4335297A (en) * | 1996-09-06 | 1998-03-26 | Eli Lilly And Company | Process and novel intermediates |
ES2441197T3 (es) * | 2007-08-28 | 2014-02-03 | Ipsen Pharma S.A.S. | Método para la síntesis química de polipéptidos y proteínas |
CN102167727B (zh) * | 2011-01-29 | 2013-05-15 | 浙江金立源药业有限公司 | 一种匹多莫德的合成方法 |
WO2016112977A1 (en) | 2015-01-15 | 2016-07-21 | Polichem S.A. | Di-pidotimod benzathine and solid forms thereof |
KR101642445B1 (ko) * | 2016-01-11 | 2016-07-26 | (주)남양통신 | 수상태양광 발전장치용 계류장치 |
CN107383162A (zh) * | 2017-07-06 | 2017-11-24 | 成都美域高制药有限公司 | 一种匹多莫德的制备方法 |
CN108640912A (zh) * | 2018-06-19 | 2018-10-12 | 广州大光制药有限公司 | 一种匹多莫德的工业化规模制备方法 |
CN111233854A (zh) * | 2019-12-30 | 2020-06-05 | 常州寅盛药业有限公司 | 一种匹多莫德杂质的制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1202426B (it) * | 1987-01-26 | 1989-02-09 | Poli Ind Chimica Spa | Derivato di acido tiazolidin-4-carbossilico,sua preparazione e composizioni farmaceutiche che lo contengono |
-
1989
- 1989-10-12 IT IT22003A patent/IT1239029B/it active IP Right Grant
-
1990
- 1990-10-08 DE DE199090119271T patent/DE422566T1/de active Pending
- 1990-10-08 EP EP90119271A patent/EP0422566B1/en not_active Expired - Lifetime
- 1990-10-08 AT AT90119271T patent/ATE121420T1/de not_active IP Right Cessation
- 1990-10-08 DK DK90119271.6T patent/DK0422566T3/da active
- 1990-10-08 ES ES90119271T patent/ES2028766T3/es not_active Expired - Lifetime
- 1990-10-08 DE DE69018755T patent/DE69018755T2/de not_active Expired - Fee Related
- 1990-10-08 IE IE359990A patent/IE67047B1/en not_active IP Right Cessation
- 1990-10-09 US US07/594,313 patent/US5110936A/en not_active Expired - Lifetime
- 1990-10-09 ZA ZA908097A patent/ZA908097B/xx unknown
- 1990-10-10 IL IL9594990A patent/IL95949A/en not_active IP Right Cessation
- 1990-10-10 KR KR1019900015999A patent/KR100195895B1/ko not_active IP Right Cessation
- 1990-10-11 FI FI905011A patent/FI95271C/fi active IP Right Grant
- 1990-10-11 AU AU64521/90A patent/AU644379B2/en not_active Ceased
- 1990-10-11 NO NO904404A patent/NO178028C/no unknown
- 1990-10-11 CA CA002027341A patent/CA2027341C/en not_active Expired - Fee Related
- 1990-10-11 HU HU906417A patent/HU210213B/hu not_active IP Right Cessation
- 1990-10-12 JP JP2275100A patent/JP2813450B2/ja not_active Expired - Fee Related
-
1991
- 1991-11-15 GR GR91300072T patent/GR910300072T1/el unknown
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