DK9390A - Kondenserede benzapiner - Google Patents

Kondenserede benzapiner Download PDF

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Publication number
DK9390A
DK9390A DK009390A DK9390A DK9390A DK 9390 A DK9390 A DK 9390A DK 009390 A DK009390 A DK 009390A DK 9390 A DK9390 A DK 9390A DK 9390 A DK9390 A DK 9390A
Authority
DK
Denmark
Prior art keywords
benzapines
condensed
compounds
transisomeric
benzazepines
Prior art date
Application number
DK009390A
Other languages
English (en)
Other versions
DK162889C (da
DK162889B (da
DK9390D0 (da
Inventor
Joel Gilbert Berger
Wei Kong Chang
Elijah Herman Gold
John Welch Clader
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of DK9390D0 publication Critical patent/DK9390D0/da
Publication of DK9390A publication Critical patent/DK9390A/da
Publication of DK162889B publication Critical patent/DK162889B/da
Application granted granted Critical
Publication of DK162889C publication Critical patent/DK162889C/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/32Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Hydrogenated Pyridines (AREA)
  • Electroluminescent Light Sources (AREA)
  • Luminescent Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK009390A 1987-07-15 1990-01-12 Substituerede hexahydrobenzindenoazepiner, fremgangsmaader til fremstilling af saadanne forbindelser, farmaceutiske praeparater indeholdende forbindelserne, anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater samt fremgangsmaade til fremstilling af saadanne farmaceutiske praeparater DK162889C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/US1987/001636 WO1989000561A1 (en) 1987-07-15 1987-07-15 Fused benzazepines
US8701636 1987-07-15
EP87110253 1987-07-16
EP87110253A EP0299101B1 (en) 1987-07-15 1987-07-16 Fused benzazepines

Publications (4)

Publication Number Publication Date
DK9390D0 DK9390D0 (da) 1990-01-12
DK9390A true DK9390A (da) 1990-03-12
DK162889B DK162889B (da) 1991-12-23
DK162889C DK162889C (da) 1992-05-11

Family

ID=26108265

Family Applications (1)

Application Number Title Priority Date Filing Date
DK009390A DK162889C (da) 1987-07-15 1990-01-12 Substituerede hexahydrobenzindenoazepiner, fremgangsmaader til fremstilling af saadanne forbindelser, farmaceutiske praeparater indeholdende forbindelserne, anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater samt fremgangsmaade til fremstilling af saadanne farmaceutiske praeparater

Country Status (13)

Country Link
EP (2) EP0363353B1 (da)
JP (1) JPH0678317B2 (da)
AT (1) ATE78467T1 (da)
AU (1) AU617651B2 (da)
DE (1) DE3780649T2 (da)
DK (1) DK162889C (da)
ES (1) ES2043623T3 (da)
FI (1) FI93212C (da)
GR (1) GR3006671T3 (da)
HU (1) HU203537B (da)
NO (1) NO177264C (da)
WO (1) WO1989000561A1 (da)
ZA (1) ZA875183B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4973586A (en) * 1986-01-16 1990-11-27 Schering Corporation Fused benzazepines, compositions of, and medical use thereof
PL168787B1 (pl) * 1989-08-03 1996-04-30 Smithkline Beecham Biolog Sposób wytwarzania czastki kompozytowej PL
US5362728A (en) * 1990-02-02 1994-11-08 Schering Corporation 4,5-bridged-2,3,4,5-tetrahydro-1H-3-benzazepine-7-ols and derivatives and compositions and methods employing such compounds
JPH07137816A (ja) * 1993-11-15 1995-05-30 Tokai Univ 地下空洞内貯蔵装置
ATE396996T1 (de) * 2002-08-29 2008-06-15 Schering Corp Selektive d1/d5 rezeptorantagonisten zur behandlung von fettleibigkeit und von zns störungen
US7504391B2 (en) * 2003-05-22 2009-03-17 Schering Corporation Selective D1/D5 receptor antagonists for the treatment of obesity and CNS disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3393192A (en) * 1965-04-26 1968-07-16 Schering Corp Novel benzazepines
CH481110A (de) * 1967-02-17 1969-11-15 Geigy Ag J R Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
US4680298A (en) * 1983-05-31 1987-07-14 Schering Corporation Tricyclic anti-allergy and use as anti-inflammatory agents
HU199805B (en) * 1986-01-16 1990-03-28 Schering Corp Process for producing condensed benzazepine derivatives and pharmaceutical compositions comprising such compounds

Also Published As

Publication number Publication date
ES2043623T3 (es) 1994-01-01
FI900175A0 (fi) 1990-01-12
EP0363353A1 (en) 1990-04-18
DK162889C (da) 1992-05-11
JPH02504629A (ja) 1990-12-27
NO177264B (no) 1995-05-08
NO177264C (no) 1995-08-16
EP0363353B1 (en) 1992-07-22
JPH0678317B2 (ja) 1994-10-05
NO900186D0 (no) 1990-01-12
EP0299101A1 (en) 1989-01-18
DK162889B (da) 1991-12-23
ZA875183B (en) 1988-04-08
AU617651B2 (en) 1991-12-05
WO1989000561A1 (en) 1989-01-26
NO900186L (no) 1990-01-12
EP0299101B1 (en) 1992-09-23
HU203537B (en) 1991-08-28
DE3780649T2 (de) 1992-12-10
FI93212C (fi) 1995-03-10
DK9390D0 (da) 1990-01-12
ATE78467T1 (de) 1992-08-15
DE3780649D1 (de) 1992-08-27
GR3006671T3 (da) 1993-06-30
FI93212B (fi) 1994-11-30
AU8037887A (en) 1989-02-13

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