ATE78467T1 - Kondensierte benzazepine. - Google Patents
Kondensierte benzazepine.Info
- Publication number
- ATE78467T1 ATE78467T1 AT87906614T AT87906614T ATE78467T1 AT E78467 T1 ATE78467 T1 AT E78467T1 AT 87906614 T AT87906614 T AT 87906614T AT 87906614 T AT87906614 T AT 87906614T AT E78467 T1 ATE78467 T1 AT E78467T1
- Authority
- AT
- Austria
- Prior art keywords
- benzazepines
- condensed
- useful
- hypertension
- isomer
- Prior art date
Links
- 150000008038 benzoazepines Chemical class 0.000 title 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229940124550 renal vasodilator Drugs 0.000 abstract 1
- -1 trans-isomer benzazepines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/32—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Electroluminescent Light Sources (AREA)
- Luminescent Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP87906614A EP0363353B1 (de) | 1987-07-15 | 1987-07-15 | Kondensierte benzazepine |
| PCT/US1987/001636 WO1989000561A1 (en) | 1987-07-15 | 1987-07-15 | Fused benzazepines |
| EP87110253A EP0299101B1 (de) | 1987-07-15 | 1987-07-16 | Kondensierte Benzazepine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE78467T1 true ATE78467T1 (de) | 1992-08-15 |
Family
ID=26108265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87906614T ATE78467T1 (de) | 1987-07-15 | 1987-07-15 | Kondensierte benzazepine. |
Country Status (13)
| Country | Link |
|---|---|
| EP (2) | EP0363353B1 (de) |
| JP (1) | JPH0678317B2 (de) |
| AT (1) | ATE78467T1 (de) |
| AU (1) | AU617651B2 (de) |
| DE (1) | DE3780649T2 (de) |
| DK (1) | DK162889C (de) |
| ES (1) | ES2043623T3 (de) |
| FI (1) | FI93212C (de) |
| GR (1) | GR3006671T3 (de) |
| HU (1) | HU203537B (de) |
| NO (1) | NO177264C (de) |
| WO (1) | WO1989000561A1 (de) |
| ZA (1) | ZA875183B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4973586A (en) | 1986-01-16 | 1990-11-27 | Schering Corporation | Fused benzazepines, compositions of, and medical use thereof |
| PL168787B1 (pl) * | 1989-08-03 | 1996-04-30 | Smithkline Beecham Biolog | Sposób wytwarzania czastki kompozytowej PL |
| US5362728A (en) * | 1990-02-02 | 1994-11-08 | Schering Corporation | 4,5-bridged-2,3,4,5-tetrahydro-1H-3-benzazepine-7-ols and derivatives and compositions and methods employing such compounds |
| JPH07137816A (ja) * | 1993-11-15 | 1995-05-30 | Tokai Univ | 地下空洞内貯蔵装置 |
| ATE396996T1 (de) * | 2002-08-29 | 2008-06-15 | Schering Corp | Selektive d1/d5 rezeptorantagonisten zur behandlung von fettleibigkeit und von zns störungen |
| JP2006526021A (ja) * | 2003-05-22 | 2006-11-16 | シェーリング コーポレイション | 肥満およびｃｎｓ障害を治療する選択的ｄ１／ｄ５レセプタアンタゴニストとしての５ｈ−ベンゾ［ｄ］ナフト［２，１−ｂ］アゼピン誘導体 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3393192A (en) * | 1965-04-26 | 1968-07-16 | Schering Corp | Novel benzazepines |
| CH481110A (de) * | 1967-02-17 | 1969-11-15 | Geigy Ag J R | Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen |
| US4680298A (en) * | 1983-05-31 | 1987-07-14 | Schering Corporation | Tricyclic anti-allergy and use as anti-inflammatory agents |
| JPH0681745B2 (ja) * | 1986-01-16 | 1994-10-19 | シェリング・コ−ポレ−ション | 縮合ベンゾアゼピン |
-
1987
- 1987-07-15 AT AT87906614T patent/ATE78467T1/de not_active IP Right Cessation
- 1987-07-15 DE DE8787906614T patent/DE3780649T2/de not_active Expired - Lifetime
- 1987-07-15 ZA ZA875183A patent/ZA875183B/xx unknown
- 1987-07-15 HU HU8552A patent/HU203537B/hu not_active IP Right Cessation
- 1987-07-15 EP EP87906614A patent/EP0363353B1/de not_active Expired - Lifetime
- 1987-07-15 WO PCT/US1987/001636 patent/WO1989000561A1/en not_active Ceased
- 1987-07-15 JP JP62506016A patent/JPH0678317B2/ja not_active Expired - Lifetime
- 1987-07-15 AU AU80378/87A patent/AU617651B2/en not_active Ceased
- 1987-07-16 ES ES87110253T patent/ES2043623T3/es not_active Expired - Lifetime
- 1987-07-16 EP EP87110253A patent/EP0299101B1/de not_active Expired - Lifetime
-
1990
- 1990-01-12 NO NO900186A patent/NO177264C/no unknown
- 1990-01-12 DK DK009390A patent/DK162889C/da active
- 1990-01-12 FI FI900175A patent/FI93212C/fi not_active IP Right Cessation
-
1992
- 1992-12-24 GR GR920403109T patent/GR3006671T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU203537B (en) | 1991-08-28 |
| DK9390A (da) | 1990-03-12 |
| FI93212B (fi) | 1994-11-30 |
| NO177264B (no) | 1995-05-08 |
| NO177264C (no) | 1995-08-16 |
| DK162889C (da) | 1992-05-11 |
| NO900186L (no) | 1990-01-12 |
| NO900186D0 (no) | 1990-01-12 |
| ES2043623T3 (es) | 1994-01-01 |
| DE3780649D1 (de) | 1992-08-27 |
| WO1989000561A1 (en) | 1989-01-26 |
| AU617651B2 (en) | 1991-12-05 |
| EP0363353A1 (de) | 1990-04-18 |
| FI900175A0 (fi) | 1990-01-12 |
| EP0299101A1 (de) | 1989-01-18 |
| DK9390D0 (da) | 1990-01-12 |
| EP0363353B1 (de) | 1992-07-22 |
| ZA875183B (en) | 1988-04-08 |
| AU8037887A (en) | 1989-02-13 |
| JPH0678317B2 (ja) | 1994-10-05 |
| JPH02504629A (ja) | 1990-12-27 |
| DK162889B (da) | 1991-12-23 |
| GR3006671T3 (de) | 1993-06-30 |
| FI93212C (fi) | 1995-03-10 |
| DE3780649T2 (de) | 1992-12-10 |
| EP0299101B1 (de) | 1992-09-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |