ATE78467T1 - Kondensierte benzazepine. - Google Patents

Kondensierte benzazepine.

Info

Publication number
ATE78467T1
ATE78467T1 AT87906614T AT87906614T ATE78467T1 AT E78467 T1 ATE78467 T1 AT E78467T1 AT 87906614 T AT87906614 T AT 87906614T AT 87906614 T AT87906614 T AT 87906614T AT E78467 T1 ATE78467 T1 AT E78467T1
Authority
AT
Austria
Prior art keywords
benzazepines
condensed
useful
hypertension
isomer
Prior art date
Application number
AT87906614T
Other languages
English (en)
Inventor
Joel Gilbert Berger
Wei Kong Chang
Elijah Herman Gold
John Welch Clader
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE78467T1 publication Critical patent/ATE78467T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/32—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Electroluminescent Light Sources (AREA)
AT87906614T 1987-07-15 1987-07-15 Kondensierte benzazepine. ATE78467T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP87906614A EP0363353B1 (de) 1987-07-15 1987-07-15 Kondensierte benzazepine
PCT/US1987/001636 WO1989000561A1 (en) 1987-07-15 1987-07-15 Fused benzazepines
EP87110253A EP0299101B1 (de) 1987-07-15 1987-07-16 Kondensierte Benzazepine

Publications (1)

Publication Number Publication Date
ATE78467T1 true ATE78467T1 (de) 1992-08-15

Family

ID=26108265

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87906614T ATE78467T1 (de) 1987-07-15 1987-07-15 Kondensierte benzazepine.

Country Status (13)

Country Link
EP (2) EP0363353B1 (de)
JP (1) JPH0678317B2 (de)
AT (1) ATE78467T1 (de)
AU (1) AU617651B2 (de)
DE (1) DE3780649T2 (de)
DK (1) DK162889C (de)
ES (1) ES2043623T3 (de)
FI (1) FI93212C (de)
GR (1) GR3006671T3 (de)
HU (1) HU203537B (de)
NO (1) NO177264C (de)
WO (1) WO1989000561A1 (de)
ZA (1) ZA875183B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4973586A (en) 1986-01-16 1990-11-27 Schering Corporation Fused benzazepines, compositions of, and medical use thereof
PL168408B1 (pl) * 1989-08-03 1996-02-29 Smithkline Beecham Biolog Sposób wytwarzania stransformowanego mikroorganizmu PL
US5362728A (en) * 1990-02-02 1994-11-08 Schering Corporation 4,5-bridged-2,3,4,5-tetrahydro-1H-3-benzazepine-7-ols and derivatives and compositions and methods employing such compounds
JPH07137816A (ja) * 1993-11-15 1995-05-30 Tokai Univ 地下空洞内貯蔵装置
CN1688584A (zh) * 2002-08-29 2005-10-26 先灵公司 治疗肥胖和中枢神经系统疾病的选择性d1/d5受体拮抗剂
JP2006526021A (ja) * 2003-05-22 2006-11-16 シェーリング　コーポレイション 肥満およびｃｎｓ障害を治療する選択的ｄ１／ｄ５レセプタアンタゴニストとしての５ｈ−ベンゾ［ｄ］ナフト［２，１−ｂ］アゼピン誘導体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3393192A (en) * 1965-04-26 1968-07-16 Schering Corp Novel benzazepines
CH481110A (de) * 1967-02-17 1969-11-15 Geigy Ag J R Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
US4680298A (en) * 1983-05-31 1987-07-14 Schering Corporation Tricyclic anti-allergy and use as anti-inflammatory agents
KR900007781B1 (ko) * 1986-01-16 1990-10-20 쉐링 코포레이션 융합된 벤즈아제핀

Also Published As

Publication number Publication date
DK162889C (da) 1992-05-11
AU8037887A (en) 1989-02-13
WO1989000561A1 (en) 1989-01-26
DK162889B (da) 1991-12-23
NO900186D0 (no) 1990-01-12
EP0299101B1 (de) 1992-09-23
DK9390D0 (da) 1990-01-12
FI93212B (fi) 1994-11-30
NO900186L (no) 1990-01-12
EP0299101A1 (de) 1989-01-18
ES2043623T3 (es) 1994-01-01
EP0363353A1 (de) 1990-04-18
EP0363353B1 (de) 1992-07-22
FI900175A0 (fi) 1990-01-12
NO177264B (no) 1995-05-08
NO177264C (no) 1995-08-16
HU203537B (en) 1991-08-28
AU617651B2 (en) 1991-12-05
DE3780649T2 (de) 1992-12-10
DE3780649D1 (de) 1992-08-27
JPH0678317B2 (ja) 1994-10-05
GR3006671T3 (de) 1993-06-30
JPH02504629A (ja) 1990-12-27
DK9390A (da) 1990-03-12
ZA875183B (en) 1988-04-08
FI93212C (fi) 1995-03-10

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee