DK159780C - (-)-1beta-ethyl-1alfa-hydroxylmethyl-1,2,3,4,6,7,12,12balfa-octahydroindolo(2,3-a)quinolizin og syreadditionssalte deraf, dens fremstilling og farmaceutisk praeparat indeholdende den - Google Patents

(-)-1beta-ethyl-1alfa-hydroxylmethyl-1,2,3,4,6,7,12,12balfa-octahydroindolo(2,3-a)quinolizin og syreadditionssalte deraf, dens fremstilling og farmaceutisk praeparat indeholdende den

Info

Publication number
DK159780C
DK159780C DK179786A DK179786A DK159780C DK 159780 C DK159780 C DK 159780C DK 179786 A DK179786 A DK 179786A DK 179786 A DK179786 A DK 179786A DK 159780 C DK159780 C DK 159780C
Authority
DK
Denmark
Prior art keywords
preparation
12balfa
1alfa
octahydroindolo
quinolizin
Prior art date
Application number
DK179786A
Other languages
Danish (da)
English (en)
Other versions
DK179786A (da
DK179786D0 (da
DK159780B (da
Inventor
Csaba Szantay
Lajos Szabo
Gyoergy Kalaus
Zsolt Szombathelyi
Egon Karpati
Bela Kiss
Csomor Katalin
Istvan Laszlovszky
Erzsebet Lapis
Laszlo Szporny
Lilla Forgacs
Csaba Kuthi
Aniko Gere
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of DK179786D0 publication Critical patent/DK179786D0/da
Publication of DK179786A publication Critical patent/DK179786A/da
Publication of DK159780B publication Critical patent/DK159780B/da
Application granted granted Critical
Publication of DK159780C publication Critical patent/DK159780C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
DK179786A 1985-04-19 1986-04-18 (-)-1beta-ethyl-1alfa-hydroxylmethyl-1,2,3,4,6,7,12,12balfa-octahydroindolo(2,3-a)quinolizin og syreadditionssalte deraf, dens fremstilling og farmaceutisk praeparat indeholdende den DK159780C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU851519A HU194221B (en) 1985-04-19 1985-04-19 Process for preparing novel octahydro-indolo/2,3-a/quinoline derivative and pharmaceutical comprising this compound
HU151985 1985-04-19

Publications (4)

Publication Number Publication Date
DK179786D0 DK179786D0 (da) 1986-04-18
DK179786A DK179786A (da) 1986-10-20
DK159780B DK159780B (da) 1990-12-03
DK159780C true DK159780C (da) 1991-04-22

Family

ID=10954847

Family Applications (1)

Application Number Title Priority Date Filing Date
DK179786A DK159780C (da) 1985-04-19 1986-04-18 (-)-1beta-ethyl-1alfa-hydroxylmethyl-1,2,3,4,6,7,12,12balfa-octahydroindolo(2,3-a)quinolizin og syreadditionssalte deraf, dens fremstilling og farmaceutisk praeparat indeholdende den

Country Status (35)

Country Link
US (1) US4806545A (pm)
JP (1) JPH072637B2 (pm)
CN (1) CN1023560C (pm)
AR (1) AR240699A1 (pm)
AT (1) AT390954B (pm)
AU (1) AU591896B2 (pm)
BE (1) BE904588A (pm)
BG (1) BG60433B2 (pm)
CA (1) CA1299574C (pm)
CH (1) CH668262A5 (pm)
CS (1) CS274276B2 (pm)
DD (1) DD244556A5 (pm)
DE (1) DE3613180C2 (pm)
DK (1) DK159780C (pm)
EG (1) EG18059A (pm)
ES (1) ES8706152A1 (pm)
FI (1) FI83870C (pm)
FR (1) FR2580649B1 (pm)
GB (1) GB2174701B (pm)
GR (1) GR861027B (pm)
HU (1) HU194221B (pm)
IE (1) IE59199B1 (pm)
IL (1) IL78538A (pm)
IN (1) IN162810B (pm)
IT (1) IT1204306B (pm)
LU (1) LU86397A1 (pm)
NL (1) NL8600976A (pm)
NO (1) NO167143C (pm)
NZ (1) NZ215879A (pm)
PH (1) PH25316A (pm)
PT (1) PT82424B (pm)
SE (1) SE460196B (pm)
SU (1) SU1438612A3 (pm)
YU (1) YU44286B (pm)
ZA (1) ZA862941B (pm)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU191454B (en) * 1984-10-05 1987-02-27 Richter Gedeon Vegyeszeti Gyar Rt.,Hu Process for producing amides of oktahydro-indolo/2,3-a/quinolyzin-1-yl-alkanecarboxylic acids and pharmaceutically acceptable acid additional salts thereof
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds
HU194220B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof
HU207070B (en) * 1990-10-31 1993-03-01 Richter Gedeon Vegyeszet Process for producing 1beta-ethyl-1alpha-hydroxymethyl-1,2,3,4,6,712,12balpha-octahydroindolo(2,3-a) quinolizine
DE19821039A1 (de) * 1998-05-11 1999-11-18 Bayer Ag Verfahren zur Herstellung von (S,S)-Benzyl-2,8-diazabicyclo[4.3.0]nonan
DE60316672T2 (de) * 2002-04-03 2008-07-17 Orion Corp. Polycyclische verbindungen als potente alpha2-adrenoceptor antagonisten
JPWO2003094917A1 (ja) * 2002-05-13 2005-09-08 高田製薬株式会社 ビントペロール含有経皮投与用医薬組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1499546A (en) * 1974-05-07 1978-02-01 Richter Gedeon Vegyeszet Indolo-quinolizidine derivatives and a process for the preparation thereof
HU170495B (pm) * 1974-05-07 1977-06-28
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds
HU194220B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof

Also Published As

Publication number Publication date
AR240699A1 (es) 1990-09-28
ATA102986A (de) 1990-01-15
DK179786A (da) 1986-10-20
HUT40433A (en) 1986-12-28
NO167143B (no) 1991-07-01
LU86397A1 (pm) 1986-09-02
DE3613180C2 (de) 1995-10-19
FR2580649B1 (fr) 1991-03-29
SU1438612A3 (ru) 1988-11-15
FI861641A0 (fi) 1986-04-18
GB8609533D0 (en) 1986-05-21
BE904588A (fr) 1986-10-14
DK179786D0 (da) 1986-04-18
IL78538A0 (en) 1986-08-31
FR2580649A1 (fr) 1986-10-24
IN162810B (pm) 1988-07-09
AU591896B2 (en) 1989-12-21
IT8620136A0 (it) 1986-04-18
FI861641L (fi) 1986-10-20
ES8706152A1 (es) 1987-06-01
SE460196B (sv) 1989-09-18
CH668262A5 (de) 1988-12-15
AU5638386A (en) 1986-10-23
SE8601799L (sv) 1986-10-20
IE59199B1 (en) 1994-01-26
ZA862941B (en) 1986-12-30
FI83870B (fi) 1991-05-31
JPS61249986A (ja) 1986-11-07
AT390954B (de) 1990-07-25
IT1204306B (it) 1989-03-01
PT82424A (en) 1986-05-01
YU62486A (en) 1988-06-30
CS286386A2 (en) 1990-09-12
EG18059A (en) 1991-06-30
CS274276B2 (en) 1991-04-11
FI83870C (fi) 1991-09-10
YU44286B (en) 1990-04-30
US4806545A (en) 1989-02-21
GB2174701B (en) 1989-02-15
NO167143C (no) 1991-10-09
NZ215879A (en) 1989-04-26
PT82424B (pt) 1988-03-03
PH25316A (en) 1991-04-30
IE861033L (en) 1986-10-19
IL78538A (en) 1989-10-31
BG60433B2 (bg) 1995-03-31
SE8601799D0 (sv) 1986-04-18
DE3613180A1 (de) 1986-10-23
HU194221B (en) 1988-01-28
JPH072637B2 (ja) 1995-01-18
GB2174701A (en) 1986-11-12
NL8600976A (nl) 1986-11-17
GR861027B (en) 1986-08-12
DK159780B (da) 1990-12-03
CA1299574C (en) 1992-04-28
CN1023560C (zh) 1994-01-19
NO861539L (no) 1986-10-20
CN86102479A (zh) 1986-10-22
DD244556A5 (de) 1987-04-08
ES554143A0 (es) 1987-06-01

Similar Documents

Publication Publication Date Title
DK414189A (da) Aminosyreforbindelse og dens anvendelse
DK165877C (da) 1,4-dihydro-6-fluor-4-oxo-1,8-naphthyridin-3-carboxylsyrederivater og salte deraf, antibakterielle praeparater indeholdende saadanne forbindelser
EP0193415A3 (en) Spiro-3-heteroazolidine compounds and salts thereof, their preparation and pharmaceutical agents thereof
NL194154B (nl) Farmaceutisch wateroplosbaar preparaat dat N-acetylcysteine en aspartame bevat.
FI892675A7 (fi) 2,6-dihalogeenipyridiini-3-karboksyylihappojohdannaiset ja niiden valmistus
DK131887D0 (da) 1,2,3,4-tetrahydro-3-carbamoyl-2-thioxo/oxo-5-pyrimidencarboxylsyre-derivater og deres anvendelse som laegemidler
DK166279C (da) 3,4-dihydro-2h-benzooebaapyranderivater, deres fremstilling og laegemidler indeholdende disse forbindelser
IT1198247B (it) Formulazioni farmaceutiche acquose di ubichinone
FI854178A7 (fi) 1,2,4-triatsolo-karbamaatti ja sen happoadditiosuolat, näiden valmistusmenetelmät ja lääkeaineet.
DK159780C (da) (-)-1beta-ethyl-1alfa-hydroxylmethyl-1,2,3,4,6,7,12,12balfa-octahydroindolo(2,3-a)quinolizin og syreadditionssalte deraf, dens fremstilling og farmaceutisk praeparat indeholdende den
FI873800A7 (fi) Nor-kolaanihappojohdannaiset, menetelmä niiden valmistamiseksi, niiden käyttö sekä niitä sisältävät farmaseuttiset seokset.
DK99085A (da) Farmaceutiske praeparater indeholdende a-vitaminsyrederivater
DK587689A (da) 2-azabicyclo(2,2,1)hept-5-en-2-eddikesyre og derivater deraf, deres fremstilling og anvendelse
DK605186A (da) 16,17-acetalsubstituerede pregnan-21-ionsyrederivater, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende saadanne forbindelser
IT8619594A1 (it) Acid 8-osso-2-ossa-l-azabiciclo 4.2.0 ottano-3-carbossilici
DK161321C (da) 5,6-dihydro-4h-cyklopenta(b)-tiofen-6-karboxylsyreforbindelser og laegemiddelpraeparat indeholdende dem
DK453485A (da) 1,2,3,4,6,7,12,1rb-octahydroindolo-(2,3-a)quinolizin-1-yl-alkancarboxylsyreamider og farmaceutisk anvendelige syreadditionssalte deraf,deres fremstilling og anvendelse
DK504386D0 (da) Gonadoliberinanaloge og farmaceutisk acceptable syreadditionssalte, deres fremstilling og anvendelse
DK527886D0 (da) 2,3,4,6-tetrasubstituerede 1,4-dihydropyridin-5-carboxylsyrederivater samt deres fremstilling og anvendelse
DK192588A (da) Pyrrolaldehyder eller farmaceutisk acceptable syreadditionssalte deraf, deres fremstilling og anvendelse
KR900007857A (ko) 1,4,2-옥사자포스폴리딘-4-아세트산, 2-알콕시-2-옥사이드의 아민염
DK343688D0 (da) Benzodipyranforbindelse og dens farmaceutiske anvendelse
DK403987A (da) Benzohydroxamsyrederivater
GB2174699B (en) Salt of 2',4'-difluoro-4-hydroxy-diphenyl-3-carboxylic acid, its preparation and use
DK220786A (da) Ascorbinsyrederivater og fremstilling og anvendelse deraf