DK158873C - Fremgangsmaade til stabilisering af et lyofiliseret farmaceutisk interferonpraeparat - Google Patents

Fremgangsmaade til stabilisering af et lyofiliseret farmaceutisk interferonpraeparat

Info

Publication number
DK158873C
DK158873C DK565882A DK565882A DK158873C DK 158873 C DK158873 C DK 158873C DK 565882 A DK565882 A DK 565882A DK 565882 A DK565882 A DK 565882A DK 158873 C DK158873 C DK 158873C
Authority
DK
Denmark
Prior art keywords
stabilizing
procedure
lyophilized pharmaceutical
interferon preparation
pharmaceutical interferon
Prior art date
Application number
DK565882A
Other languages
Danish (da)
English (en)
Other versions
DK565882A (da
DK158873B (da
DK158771B (da
Inventor
Henry King Hong Kwan
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26989028&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK158873(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from ZA828580A external-priority patent/ZA828580B/xx
Application filed by Schering Corp filed Critical Schering Corp
Publication of DK565882A publication Critical patent/DK565882A/da
Publication of DK158771B publication Critical patent/DK158771B/da
Publication of DK158873B publication Critical patent/DK158873B/da
Application granted granted Critical
Publication of DK158873C publication Critical patent/DK158873C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
DK565882A 1981-12-23 1982-12-21 Fremgangsmaade til stabilisering af et lyofiliseret farmaceutisk interferonpraeparat DK158873C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US33405281A 1981-12-23 1981-12-23
US33405281 1981-12-23
ZA8208580 1982-11-19
ZA828580A ZA828580B (en) 1981-12-23 1982-11-19 Interferon formulations

Publications (4)

Publication Number Publication Date
DK565882A DK565882A (da) 1983-06-24
DK158771B DK158771B (da) 1990-07-16
DK158873B DK158873B (da) 1990-07-30
DK158873C true DK158873C (da) 1990-12-31

Family

ID=26989028

Family Applications (1)

Application Number Title Priority Date Filing Date
DK565882A DK158873C (da) 1981-12-23 1982-12-21 Fremgangsmaade til stabilisering af et lyofiliseret farmaceutisk interferonpraeparat

Country Status (18)

Country Link
US (1) US4496537A (fi)
EP (1) EP0082481B2 (fi)
AU (1) AU558966B2 (fi)
CA (1) CA1207665A (fi)
DE (1) DE3262575D1 (fi)
DK (1) DK158873C (fi)
FI (1) FI70794C (fi)
HK (1) HK94487A (fi)
HU (1) HU190649B (fi)
IE (1) IE54468B1 (fi)
IL (1) IL67517A (fi)
MY (1) MY8700705A (fi)
NO (1) NO161036C (fi)
NZ (1) NZ202856A (fi)
OA (1) OA07282A (fi)
PH (1) PH19869A (fi)
PT (1) PT76013B (fi)
SG (1) SG70687G (fi)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4600583A (en) * 1982-09-07 1986-07-15 Tetra Consultants Inc. Pharmaceutical compositions
US4469228A (en) * 1983-05-31 1984-09-04 Schering Corporation Interferon kit
JPH0651641B2 (ja) * 1983-08-29 1994-07-06 株式会社ミドリ十字 ガンマ・インターフェロン組成物
JPS6034919A (ja) * 1983-08-04 1985-02-22 Green Cross Corp:The ガンマ・インタ−フェロン組成物
US4855134A (en) * 1983-10-14 1989-08-08 Sumitomo Pharmaceuticals Company, Limited Sustained-release preparation
JPS60243028A (ja) * 1984-04-28 1985-12-03 Kyowa Hakko Kogyo Co Ltd インタ−フエロンの可溶化方法
EP0168008A3 (en) * 1984-07-10 1986-12-30 Takeda Chemical Industries, Ltd. Stable composition of gamma-interferon
US5196323A (en) * 1985-04-27 1993-03-23 Boehringer Ingelheim International Gmbh Process for preparing and purifying alpha-interferon
US4847079A (en) * 1985-07-29 1989-07-11 Schering Corporation Biologically stable interferon compositions comprising thimerosal
DE3628468A1 (de) * 1986-08-21 1988-03-03 Thomae Gmbh Dr K Neue applikationsformen fuer (alpha)-interferone
CA1320905C (en) * 1986-11-06 1993-08-03 Joseph M. Cummins Treatment of immuno-resistant disease
US4851220A (en) * 1986-11-26 1989-07-25 Schering Corporation Stable oleaginous gel
US4853218A (en) * 1987-02-24 1989-08-01 Schering Corporation Zinc-protamine-alpha interferon complex
US4895716A (en) * 1987-06-09 1990-01-23 Biogen, Inc. Stabilized formulations of gamma interferons
US4871538A (en) * 1987-07-13 1989-10-03 Schering Corporation Insoluble copper-alpha interferon complex
US5151265A (en) * 1987-11-03 1992-09-29 Genentech, Inc. Gamma interferon formulation
US5004605A (en) * 1987-12-10 1991-04-02 Cetus Corporation Low pH pharmaceutical compositions of recombinant β-interferon
US5236704A (en) * 1988-01-28 1993-08-17 Sumitomo Pharmaceuticals Co., Ltd. Controlled release formulation
US5078997A (en) * 1988-07-13 1992-01-07 Cetus Corporation Pharmaceutical composition for interleukin-2 containing physiologically compatible stabilizers
US5165921A (en) * 1989-01-23 1992-11-24 National Geno Sciences, Inc. Method for treating condyloma acuminatum with interferon
IT1240314B (it) * 1989-09-28 1993-12-07 Immunobiology Research Institutes, Inc. Formulazioni acquose stabilizzate di piccoli peptidi.
US5863530A (en) * 1991-10-11 1999-01-26 Spruson & Ferguson Treating ophthalmic fibrosis using interferon-α
CA2120950A1 (en) * 1991-10-11 1993-04-15 Mark C. Gillies Treating ophthalmic fibrosis using interferon-alpha
AU669132B2 (en) * 1991-10-11 1996-05-30 Mark Cedric Gillies Treating ophthalmic fibrosis using interferon-alpha
US5236707A (en) * 1991-11-08 1993-08-17 Dallas Biotherapeutics, Inc. Stabilization of human interferon
LT3987B (en) 1992-02-17 1996-06-25 Fermentas Biotech Inst Stabilized interferon compositions
US5358708A (en) * 1993-01-29 1994-10-25 Schering Corporation Stabilization of protein formulations
US6270757B1 (en) * 1994-04-21 2001-08-07 Genetics Institute, Inc. Formulations for IL-11
US6399296B1 (en) * 1994-07-20 2002-06-04 The General Hospital Corporation Interaction trap systems for detecting protein interactions
US5766582A (en) * 1994-10-11 1998-06-16 Schering Corporation Stable, aqueous alfa interferon solution formulations
WO1996024369A1 (en) * 1995-02-06 1996-08-15 Genetics Institute, Inc. Formulations for il-12
US5656730A (en) * 1995-04-07 1997-08-12 Enzon, Inc. Stabilized monomeric protein compositions
US6540993B1 (en) * 1995-06-27 2003-04-01 Wyeth Method of treating inflammatory bowel disease using a topical formulation of IL-11
US6126933A (en) * 1995-06-27 2000-10-03 Genetics Institute Methods of treating inflammatory bowel diseases by administering IL-11
US20030190307A1 (en) 1996-12-24 2003-10-09 Biogen, Inc. Stable liquid interferon formulations
KR20000069664A (ko) * 1996-12-24 2000-11-25 아스트루 마이클 제이 안정한 액체 인터페론 제제
EP1426058A3 (de) † 1997-09-23 2004-07-28 Dr. Rentschler Biotechnologie GmbH Flüssige Interferon-Beta Formulierungen
ES2268800T3 (es) * 1997-10-14 2007-03-16 Eisai Co., Ltd. Formulacion farmaceutica que comprende glicina como estabilizador.
US7230014B1 (en) 1997-10-14 2007-06-12 Eisai Co., Ltd. Pharmaceutical formulation comprising glycine as a stabilizer
US8563803B2 (en) * 1997-10-16 2013-10-22 Synageva Biopharma Corp. Method of making protein in an egg of a transgenic chicken
US7511120B2 (en) * 1997-10-16 2009-03-31 Synageva Biopharma Corp. Glycosylated G-CSF obtained from a transgenic chicken
US20090074718A1 (en) * 1997-10-16 2009-03-19 Ivarie Robert D Avian derived erythropoietin
US20040019923A1 (en) * 1997-10-16 2004-01-29 Ivarie Robert D. Exogenous proteins expressed in avians and their eggs
US7129390B2 (en) 1997-10-16 2006-10-31 Avigenics, Inc Poultry Derived Glycosylated Interferon Alpha 2b
US20030166525A1 (en) * 1998-07-23 2003-09-04 Hoffmann James Arthur FSH Formulation
US6281337B1 (en) 1998-11-12 2001-08-28 Schering Corporation Methods for conversion of protein isoforms
DE69942655D1 (de) 1998-11-12 2010-09-16 Schering Corp Verfahren zur Umwandlung von Interferon-Isoformen und daraus hergestellte Produkte
DE60019458T2 (de) * 1999-12-14 2006-02-23 Thermo BioStar, Inc., Boulder Stabilisierendes verdünnungsmittel für polypeptide und antigene
WO2002036627A2 (en) 2000-11-03 2002-05-10 Pbl Biomedical Laboratories Interferons, uses and compositions related thereto
EP1356809A4 (en) * 2000-12-28 2008-05-14 Takeda Pharmaceutical SUSTAINED RELEASE PREPARATIONS
AR034749A1 (es) * 2001-07-09 2004-03-17 Schering Ag Formulaciones de interferon beta humano
JP2005526151A (ja) 2002-01-18 2005-09-02 バイオゲン アイデック エムエー インク． 生物学的に活性な化合物の結合のための部分を有するポリアルキレングリコール
US20050232899A1 (en) * 2002-05-31 2005-10-20 Aradigm Corporation Compositions methods and systems for pulmonary delivery of recombinant human interferon alpha-2b
US6830744B2 (en) 2002-05-31 2004-12-14 Aradigm Corporation Compositions methods and systems for pulmonary delivery of recombinant human interferon alpha-2b
US7803362B2 (en) * 2003-01-24 2010-09-28 Synageva Biopharma Corp. Glycosylated interferon alpha
RS57872B1 (sr) * 2003-04-02 2018-12-31 Ares Trading Sa Tečne farmaceutske formulacije fsh i lh zajedno sa nejonskim surfaktantom
DK1638595T3 (da) * 2003-06-20 2013-04-08 Ares Trading Sa Frysetørrede FSH-/LH-formuleringer
KR20070045244A (ko) * 2004-08-12 2007-05-02 쉐링 코포레이션 안정한 페길화된 인터페론 제형
JP2008531553A (ja) * 2005-02-25 2008-08-14 メディジーンズ カンパニー リミテッド 血漿または血清を含むアベリノ角膜ジストロフィー治療用の医薬組成物
US20070003564A1 (en) * 2005-06-30 2007-01-04 Hurley John K Diluent for immunohistochemistry
WO2008048228A2 (en) * 2005-08-12 2008-04-24 Department Of The Army Glycine stabilized lyophilized plasma
CU23432B6 (es) 2005-11-02 2009-10-16 Ct Ingenieria Genetica Biotech Formulaciones estabilizadas que contienen a los interferones gamma y alfa en proporciones potenciadoras
US7812127B2 (en) 2006-03-17 2010-10-12 Synageva Biopharma Corp. Glycosylated human G-CSF
US20090105462A1 (en) * 2006-11-09 2009-04-23 Ivarie Robert D Glycosylated erythropoietin
EP2097068B1 (en) * 2006-11-24 2013-09-04 Cadila Healthcare Limited Formulations of peg-interferon alpha conjugates
KR101471445B1 (ko) 2007-01-26 2014-12-15 시나게바 바이오파르마, 코포레이션 조류에서 이식유전자 발현
JP5513380B2 (ja) 2007-06-25 2014-06-04 アムジエン・インコーポレーテツド 肝細胞増殖因子に対する特異的結合剤の組成物
US20100297081A1 (en) * 2007-12-18 2010-11-25 Huang Yanshan Pharmaceutical formulation containing recombinant human serum albumin-interferon alpha fusion protein
WO2010033854A2 (en) 2008-09-19 2010-03-25 Synageva Biopharma Corp. Avian derived fusion proteins
RU2555332C2 (ru) 2009-11-03 2015-07-10 Грифольс Терапьютикс Инк. Композиция, способ и набор для альфа-1 ингибитора протеазы
RU2540480C2 (ru) 2009-11-24 2015-02-10 Грифольс Терапьютикс Инк. Способы, композиции и наборы для лиофилизации
US20130008191A1 (en) * 2011-07-07 2013-01-10 Suchak Naresh J Methods for freezing and thawing proteins
US11318207B2 (en) 2014-08-19 2022-05-03 Biogen Ma Inc. Pegylation method
CN106421755A (zh) * 2016-11-03 2017-02-22 广州凯耀资产管理有限公司 一种干扰素组合物及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2553497A (en) * 1946-02-04 1951-05-15 L Inst De Serotherapie Hemopoi Hemostatic composition of thrombin and glycocoll
US2806815A (en) * 1955-04-12 1957-09-17 Ortho Pharma Corp Stabilized hyaluronidase
GB866423A (en) * 1958-03-21 1961-04-26 Armour & Co Improvements in or relating to chymotrypsin solutions
US3016398A (en) * 1959-04-06 1962-01-09 Staley Mfg Co A E Stabilized phytic acid solutions and methods of preparation thereof
GB900115A (en) * 1960-06-15 1962-07-04 Armour & Co Improvements in or relating to trypsin solutions
JPS5495795A (en) * 1978-01-13 1979-07-28 Toray Ind Inc Production of interferon
IN150740B (fi) * 1978-11-24 1982-12-04 Hoffmann La Roche
JPS55102519A (en) * 1979-01-31 1980-08-05 Green Cross Corp:The Stabilization of interferon
US4198479A (en) * 1979-03-30 1980-04-15 Merck & Co., Inc. Replacement of animal serum proteins by human albumin for growth and interferon production by Namalva cells
US4252791A (en) * 1979-10-19 1981-02-24 The Medical College Of Wisconsin, Inc. Interferon stabilization
US4337242A (en) * 1980-02-05 1982-06-29 Merck & Co., Inc. Vaccine stabilizer containing L-glutamic acid and L-arginine
FR2505657A1 (fr) * 1981-05-13 1982-11-19 Pasteur Institut Perfectionnements apportes aux agents de stabilisation de virus vivants pour la preparation de vaccins, et vaccins stabilises contenant lesdits agents de stabilisation

Also Published As

Publication number Publication date
IE54468B1 (en) 1989-10-25
IL67517A (en) 1988-11-30
FI70794B (fi) 1986-07-18
FI70794C (fi) 1986-10-27
PH19869A (en) 1986-08-13
SG70687G (en) 1988-02-19
EP0082481B2 (en) 1990-09-12
EP0082481A1 (en) 1983-06-29
FI824366A0 (fi) 1982-12-20
NO824285L (no) 1983-06-24
IL67517A0 (en) 1983-05-15
NO161036C (no) 1989-06-28
MY8700705A (en) 1987-12-31
AU9168882A (en) 1983-06-30
NO161036B (no) 1989-03-20
OA07282A (fr) 1984-11-30
FI824366L (fi) 1983-06-24
DK565882A (da) 1983-06-24
HU190649B (en) 1986-09-29
EP0082481B1 (en) 1985-03-13
NZ202856A (en) 1985-12-13
IE823046L (en) 1983-06-23
PT76013A (en) 1983-01-01
CA1207665A (en) 1986-07-15
DE3262575D1 (en) 1985-04-18
HK94487A (en) 1987-12-18
DK158873B (da) 1990-07-30
DK158771B (da) 1990-07-16
AU558966B2 (en) 1987-02-19
US4496537A (en) 1985-01-29
PT76013B (en) 1986-03-11

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