DK518686A - Fremgangsmaade til fremstilling af alfa-l-aspartyl-l-phenylalanin-methylester - Google Patents

Fremgangsmaade til fremstilling af alfa-l-aspartyl-l-phenylalanin-methylester

Info

Publication number
DK518686A
DK518686A DK518686A DK518686A DK518686A DK 518686 A DK518686 A DK 518686A DK 518686 A DK518686 A DK 518686A DK 518686 A DK518686 A DK 518686A DK 518686 A DK518686 A DK 518686A
Authority
DK
Denmark
Prior art keywords
aspartyl
procedure
methyl ester
phenylalanine methyl
alfa
Prior art date
Application number
DK518686A
Other languages
English (en)
Other versions
DK518686D0 (da
Inventor
Jacob Shya Tou
Billy Dale Vineyard
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of DK518686D0 publication Critical patent/DK518686D0/da
Publication of DK518686A publication Critical patent/DK518686A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/801—Peptide sweetners

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK518686A 1985-10-31 1986-10-30 Fremgangsmaade til fremstilling af alfa-l-aspartyl-l-phenylalanin-methylester DK518686A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/793,601 US4677220A (en) 1985-10-31 1985-10-31 Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester

Publications (2)

Publication Number Publication Date
DK518686D0 DK518686D0 (da) 1986-10-30
DK518686A true DK518686A (da) 1987-05-01

Family

ID=25160317

Family Applications (1)

Application Number Title Priority Date Filing Date
DK518686A DK518686A (da) 1985-10-31 1986-10-30 Fremgangsmaade til fremstilling af alfa-l-aspartyl-l-phenylalanin-methylester

Country Status (6)

Country Link
US (1) US4677220A (da)
EP (1) EP0221878A3 (da)
JP (1) JPS62108900A (da)
CA (1) CA1298434C (da)
DK (1) DK518686A (da)
ES (1) ES2000038A4 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6344594A (ja) * 1986-08-11 1988-02-25 Ajinomoto Co Inc Ｎ−保護−α−Ｌ−アスパルチル−Ｌ−フエニルアラニンの分離方法
US4892820A (en) * 1987-06-10 1990-01-09 The Nutrasweet Company Solvent system for enzymatic coupling process
US4992552A (en) * 1988-08-31 1991-02-12 Eastman Kodak Company Process for preparation of amino acids
US5214145A (en) * 1988-08-31 1993-05-25 Eastman Kodak Company Trisubstituted piperazin-2,5-diones
US5144073A (en) * 1988-08-31 1992-09-01 Hubbs John C Process for preparation of dipeptides
EP0478729B1 (en) * 1990-03-15 1996-08-21 The Nutrasweet Company Process for manufacturing aspartame from a diketopiperazine and novel intermediates and derivatives therefor
JP3163661B2 (ja) * 1991-08-05 2001-05-08 味の素株式会社 α−Ｌ−アスパルチル−Ｌ−フェニルアラニンメチルエステル、及びＬ−フェニルアラニン、Ｌ−アスパラギン酸の回収方法
ES2042417B1 (es) * 1992-05-18 1994-06-01 Genesis Para La Investigacion Procedimiento de obtencion de alfa-aspartame.
KR101285945B1 (ko) * 2011-05-23 2013-07-12 씨제이제일제당 (주) Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및 이를 이용한 ｌ-라이신의 제조방법

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1309605A (en) * 1970-01-31 1973-03-14 Ajinomoto Kk Process for producing alpha-dipeptide esters of l-aspartic acid
JPS4941425B1 (da) * 1970-10-26 1974-11-08
BE791544A (fr) * 1971-11-19 1973-05-17 Stamicarbon Preparation d'esters alkyliques de dipeptide
US4029701A (en) * 1972-03-30 1977-06-14 General Foods Corporation Sweetening with hydrohalide salts of dipeptide sweeteners
JPS4913372A (da) * 1972-06-01 1974-02-05
JPS5113737A (en) * 1974-07-23 1976-02-03 Ajinomoto Kk Arufua ll asuparuchiru ll fueniruaraninteikyuarukiruesuteruno seizoho
US4173562A (en) * 1976-12-27 1979-11-06 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester
JPS59219258A (ja) * 1983-05-28 1984-12-10 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル又はその塩酸塩の製法
GB2140805B (en) * 1983-05-31 1986-08-13 Erba Farmitalia Isolation of aspartame
US4618695A (en) * 1983-06-02 1986-10-21 Ajinomoto Co., Inc. Method of preparing methyl ester and its hydrochloride

Also Published As

Publication number Publication date
EP0221878A3 (en) 1989-05-31
JPS62108900A (ja) 1987-05-20
ES2000038A4 (es) 1987-10-16
EP0221878A2 (en) 1987-05-13
US4677220A (en) 1987-06-30
CA1298434C (en) 1992-03-31
DK518686D0 (da) 1986-10-30

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Legal Events

Date Code Title Description
A0 Application filed
AHB Application shelved due to non-payment