IL67517A - Stabilized alpha-interferon formulations and their preparation - Google Patents

Stabilized alpha-interferon formulations and their preparation

Info

Publication number
IL67517A
IL67517A IL67517A IL6751782A IL67517A IL 67517 A IL67517 A IL 67517A IL 67517 A IL67517 A IL 67517A IL 6751782 A IL6751782 A IL 6751782A IL 67517 A IL67517 A IL 67517A
Authority
IL
Israel
Prior art keywords
preparation
stabilized alpha
interferon formulations
interferon
formulations
Prior art date
Application number
IL67517A
Other languages
English (en)
Other versions
IL67517A0 (en
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26989028&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL67517(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from ZA828580A external-priority patent/ZA828580B/xx
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL67517A0 publication Critical patent/IL67517A0/xx
Publication of IL67517A publication Critical patent/IL67517A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
IL67517A 1981-12-23 1982-12-20 Stabilized alpha-interferon formulations and their preparation IL67517A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33405281A 1981-12-23 1981-12-23
ZA828580A ZA828580B (en) 1981-12-23 1982-11-19 Interferon formulations

Publications (2)

Publication Number Publication Date
IL67517A0 IL67517A0 (en) 1983-05-15
IL67517A true IL67517A (en) 1988-11-30

Family

ID=26989028

Family Applications (1)

Application Number Title Priority Date Filing Date
IL67517A IL67517A (en) 1981-12-23 1982-12-20 Stabilized alpha-interferon formulations and their preparation

Country Status (18)

Country Link
US (1) US4496537A (fi)
EP (1) EP0082481B2 (fi)
AU (1) AU558966B2 (fi)
CA (1) CA1207665A (fi)
DE (1) DE3262575D1 (fi)
DK (1) DK158873C (fi)
FI (1) FI70794C (fi)
HK (1) HK94487A (fi)
HU (1) HU190649B (fi)
IE (1) IE54468B1 (fi)
IL (1) IL67517A (fi)
MY (1) MY8700705A (fi)
NO (1) NO161036C (fi)
NZ (1) NZ202856A (fi)
OA (1) OA07282A (fi)
PH (1) PH19869A (fi)
PT (1) PT76013B (fi)
SG (1) SG70687G (fi)

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US4469228A (en) * 1983-05-31 1984-09-04 Schering Corporation Interferon kit
JPH0651641B2 (ja) * 1983-08-29 1994-07-06 株式会社ミドリ十字 ガンマ・インターフェロン組成物
JPS6034919A (ja) * 1983-08-04 1985-02-22 Green Cross Corp:The ガンマ・インタ−フェロン組成物
US4855134A (en) * 1983-10-14 1989-08-08 Sumitomo Pharmaceuticals Company, Limited Sustained-release preparation
JPS60243028A (ja) * 1984-04-28 1985-12-03 Kyowa Hakko Kogyo Co Ltd インタ−フエロンの可溶化方法
EP0168008A3 (en) * 1984-07-10 1986-12-30 Takeda Chemical Industries, Ltd. Stable composition of gamma-interferon
US5196323A (en) * 1985-04-27 1993-03-23 Boehringer Ingelheim International Gmbh Process for preparing and purifying alpha-interferon
US4847079A (en) * 1985-07-29 1989-07-11 Schering Corporation Biologically stable interferon compositions comprising thimerosal
DE3628468A1 (de) * 1986-08-21 1988-03-03 Thomae Gmbh Dr K Neue applikationsformen fuer (alpha)-interferone
CA1320905C (en) * 1986-11-06 1993-08-03 Joseph M. Cummins Treatment of immuno-resistant disease
US4851220A (en) * 1986-11-26 1989-07-25 Schering Corporation Stable oleaginous gel
US4853218A (en) * 1987-02-24 1989-08-01 Schering Corporation Zinc-protamine-alpha interferon complex
US4895716A (en) * 1987-06-09 1990-01-23 Biogen, Inc. Stabilized formulations of gamma interferons
US4871538A (en) * 1987-07-13 1989-10-03 Schering Corporation Insoluble copper-alpha interferon complex
US5151265A (en) * 1987-11-03 1992-09-29 Genentech, Inc. Gamma interferon formulation
US5004605A (en) * 1987-12-10 1991-04-02 Cetus Corporation Low pH pharmaceutical compositions of recombinant β-interferon
ES2058351T3 (es) * 1988-01-29 1994-11-01 Sumitomo Pharma Un procedimiento para producir una formulacion de liberacion sostenida que es adecuada para el uso humano y veterinario.
US5078997A (en) * 1988-07-13 1992-01-07 Cetus Corporation Pharmaceutical composition for interleukin-2 containing physiologically compatible stabilizers
US5165921A (en) * 1989-01-23 1992-11-24 National Geno Sciences, Inc. Method for treating condyloma acuminatum with interferon
IT1240314B (it) * 1989-09-28 1993-12-07 Immunobiology Research Institutes, Inc. Formulazioni acquose stabilizzate di piccoli peptidi.
JPH07501320A (ja) * 1991-10-11 1995-02-09 ギリーズ，マーク・セドリック インタ−フェロン・アルファによる眼線維症の治療
US5863530A (en) * 1991-10-11 1999-01-26 Spruson & Ferguson Treating ophthalmic fibrosis using interferon-α
AU669132B2 (en) * 1991-10-11 1996-05-30 Mark Cedric Gillies Treating ophthalmic fibrosis using interferon-alpha
US5236707A (en) * 1991-11-08 1993-08-17 Dallas Biotherapeutics, Inc. Stabilization of human interferon
LT3987B (en) 1992-02-17 1996-06-25 Fermentas Biotech Inst Stabilized interferon compositions
US5358708A (en) * 1993-01-29 1994-10-25 Schering Corporation Stabilization of protein formulations
US6270757B1 (en) * 1994-04-21 2001-08-07 Genetics Institute, Inc. Formulations for IL-11
US6399296B1 (en) * 1994-07-20 2002-06-04 The General Hospital Corporation Interaction trap systems for detecting protein interactions
US5766582A (en) * 1994-10-11 1998-06-16 Schering Corporation Stable, aqueous alfa interferon solution formulations
AU695129B2 (en) * 1995-02-06 1998-08-06 Genetics Institute, Llc Formulations for IL-12
US5656730A (en) * 1995-04-07 1997-08-12 Enzon, Inc. Stabilized monomeric protein compositions
US6540993B1 (en) * 1995-06-27 2003-04-01 Wyeth Method of treating inflammatory bowel disease using a topical formulation of IL-11
US6126933A (en) * 1995-06-27 2000-10-03 Genetics Institute Methods of treating inflammatory bowel diseases by administering IL-11
ES2224290T5 (es) * 1996-12-24 2012-03-12 Biogen Idec Ma Inc. Formulaciones l�?quidas estables de interferón.
US20030190307A1 (en) * 1996-12-24 2003-10-09 Biogen, Inc. Stable liquid interferon formulations
PT1017413E (pt) 1997-09-23 2003-02-28 Rentschler Biotech Gmbh Formulacoes liquidas de interferao (beta)
DK1039905T3 (da) * 1997-10-14 2006-11-06 Eisai Co Ltd Farmaceutisk formulering omfattende glycin som en stabilisator
US7230014B1 (en) 1997-10-14 2007-06-12 Eisai Co., Ltd. Pharmaceutical formulation comprising glycine as a stabilizer
US8563803B2 (en) * 1997-10-16 2013-10-22 Synageva Biopharma Corp. Method of making protein in an egg of a transgenic chicken
US20090074718A1 (en) * 1997-10-16 2009-03-19 Ivarie Robert D Avian derived erythropoietin
US7511120B2 (en) * 1997-10-16 2009-03-31 Synageva Biopharma Corp. Glycosylated G-CSF obtained from a transgenic chicken
US7129390B2 (en) * 1997-10-16 2006-10-31 Avigenics, Inc Poultry Derived Glycosylated Interferon Alpha 2b
US20040019923A1 (en) * 1997-10-16 2004-01-29 Ivarie Robert D. Exogenous proteins expressed in avians and their eggs
US20030166525A1 (en) * 1998-07-23 2003-09-04 Hoffmann James Arthur FSH Formulation
TW577894B (en) 1998-11-12 2004-03-01 Schering Corp Methods for conversion of protein isoforms and products thereof
US6281337B1 (en) 1998-11-12 2001-08-28 Schering Corporation Methods for conversion of protein isoforms
WO2001044441A1 (en) * 1999-12-14 2001-06-21 Thermo Biostar, Inc. Stabilizing diluent for polypeptides and antigens
WO2002036627A2 (en) 2000-11-03 2002-05-10 Pbl Biomedical Laboratories Interferons, uses and compositions related thereto
EP1356809A4 (en) * 2000-12-28 2008-05-14 Takeda Pharmaceutical SUSTAINED RELEASE PREPARATIONS
UY27373A1 (es) * 2001-07-09 2003-02-28 Schering Ag Formulaciones de interferón beta-humano
EP3669887A1 (en) 2002-01-18 2020-06-24 Biogen MA Inc. Polyalkylene polymer compounds and uses thereof
US20050232899A1 (en) * 2002-05-31 2005-10-20 Aradigm Corporation Compositions methods and systems for pulmonary delivery of recombinant human interferon alpha-2b
US6830744B2 (en) 2002-05-31 2004-12-14 Aradigm Corporation Compositions methods and systems for pulmonary delivery of recombinant human interferon alpha-2b
US7803362B2 (en) * 2003-01-24 2010-09-28 Synageva Biopharma Corp. Glycosylated interferon alpha
CA2518903C (en) * 2003-04-02 2013-02-05 Ares Trading S.A. Liquid pharmaceutical formulations of fsh and lh together with a non-ionic surfactant
ES2414705T3 (es) * 2003-06-20 2013-07-22 Ares Trading S.A. Formulaciones liofilizadas de FSH/LH
US7632491B2 (en) * 2004-08-12 2009-12-15 Schering Corporation Stable pegylated interferon formulation
US20080064862A1 (en) * 2004-12-29 2008-03-13 Avigenics, Inc. Transgene expression in a avians
JP2008531553A (ja) * 2005-02-25 2008-08-14 メディジーンズ カンパニー リミテッド 血漿または血清を含むアベリノ角膜ジストロフィー治療用の医薬組成物
US20070003564A1 (en) * 2005-06-30 2007-01-04 Hurley John K Diluent for immunohistochemistry
WO2008048228A2 (en) * 2005-08-12 2008-04-24 Department Of The Army Glycine stabilized lyophilized plasma
CU23432B6 (es) 2005-11-02 2009-10-16 Ct Ingenieria Genetica Biotech Formulaciones estabilizadas que contienen a los interferones gamma y alfa en proporciones potenciadoras
US7812127B2 (en) 2006-03-17 2010-10-12 Synageva Biopharma Corp. Glycosylated human G-CSF
US20090105462A1 (en) * 2006-11-09 2009-04-23 Ivarie Robert D Glycosylated erythropoietin
EA018440B1 (ru) * 2006-11-24 2013-08-30 Кадила Хелзкэр Лимитед Композиции конъюгатов пэг-интерферон альфа
US7951368B2 (en) 2007-06-25 2011-05-31 Amgen Inc. Compositions of specific binding agents to hepatocyte growth factor
US20100297081A1 (en) * 2007-12-18 2010-11-25 Huang Yanshan Pharmaceutical formulation containing recombinant human serum albumin-interferon alpha fusion protein
WO2010033854A2 (en) 2008-09-19 2010-03-25 Synageva Biopharma Corp. Avian derived fusion proteins
ES2679819T3 (es) 2009-11-03 2018-08-31 Grifols Therapeutics Inc. Composición, método y kit para inhibidor de alfa-1 proteinasa
AU2010324839B2 (en) 2009-11-24 2015-02-19 Grifols Therapeutics Inc. Lyophilization methods, compositions, and kits
US20130008191A1 (en) * 2011-07-07 2013-01-10 Suchak Naresh J Methods for freezing and thawing proteins
WO2017030563A1 (en) 2014-08-19 2017-02-23 Biogen Ma Inc Pegylation method
CN106421755A (zh) * 2016-11-03 2017-02-22 广州凯耀资产管理有限公司 一种干扰素组合物及其制备方法

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US2553497A (en) * 1946-02-04 1951-05-15 L Inst De Serotherapie Hemopoi Hemostatic composition of thrombin and glycocoll
US2806815A (en) * 1955-04-12 1957-09-17 Ortho Pharma Corp Stabilized hyaluronidase
GB866423A (en) * 1958-03-21 1961-04-26 Armour & Co Improvements in or relating to chymotrypsin solutions
US3016398A (en) * 1959-04-06 1962-01-09 Staley Mfg Co A E Stabilized phytic acid solutions and methods of preparation thereof
GB900115A (en) * 1960-06-15 1962-07-04 Armour & Co Improvements in or relating to trypsin solutions
JPS5495795A (en) * 1978-01-13 1979-07-28 Toray Ind Inc Production of interferon
IN150740B (fi) * 1978-11-24 1982-12-04 Hoffmann La Roche
JPS55102519A (en) * 1979-01-31 1980-08-05 Green Cross Corp:The Stabilization of interferon
US4198479A (en) * 1979-03-30 1980-04-15 Merck & Co., Inc. Replacement of animal serum proteins by human albumin for growth and interferon production by Namalva cells
US4252791A (en) * 1979-10-19 1981-02-24 The Medical College Of Wisconsin, Inc. Interferon stabilization
US4337242A (en) * 1980-02-05 1982-06-29 Merck & Co., Inc. Vaccine stabilizer containing L-glutamic acid and L-arginine
FR2505657A1 (fr) * 1981-05-13 1982-11-19 Pasteur Institut Perfectionnements apportes aux agents de stabilisation de virus vivants pour la preparation de vaccins, et vaccins stabilises contenant lesdits agents de stabilisation

Also Published As

Publication number Publication date
DE3262575D1 (en) 1985-04-18
IE54468B1 (en) 1989-10-25
AU558966B2 (en) 1987-02-19
IL67517A0 (en) 1983-05-15
FI70794C (fi) 1986-10-27
HK94487A (en) 1987-12-18
DK158873C (da) 1990-12-31
FI824366A0 (fi) 1982-12-20
NO161036B (no) 1989-03-20
CA1207665A (en) 1986-07-15
MY8700705A (en) 1987-12-31
US4496537A (en) 1985-01-29
DK158771B (da) 1990-07-16
DK565882A (da) 1983-06-24
PT76013A (en) 1983-01-01
NO161036C (no) 1989-06-28
OA07282A (fr) 1984-11-30
EP0082481A1 (en) 1983-06-29
HU190649B (en) 1986-09-29
EP0082481B1 (en) 1985-03-13
NO824285L (no) 1983-06-24
AU9168882A (en) 1983-06-30
FI824366L (fi) 1983-06-24
SG70687G (en) 1988-02-19
PH19869A (en) 1986-08-13
NZ202856A (en) 1985-12-13
PT76013B (en) 1986-03-11
FI70794B (fi) 1986-07-18
IE823046L (en) 1983-06-23
EP0082481B2 (en) 1990-09-12
DK158873B (da) 1990-07-30

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Legal Events

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