DK153879C - Fremgangsmaade til fremstilling af 2'-methyl-2'-hydroxypropyl-piperazin-1-carboxylatforbindelser - Google Patents

Fremgangsmaade til fremstilling af 2'-methyl-2'-hydroxypropyl-piperazin-1-carboxylatforbindelser

Info

Publication number
DK153879C
DK153879C DK019387A DK19387A DK153879C DK 153879 C DK153879 C DK 153879C DK 019387 A DK019387 A DK 019387A DK 19387 A DK19387 A DK 19387A DK 153879 C DK153879 C DK 153879C
Authority
DK
Denmark
Prior art keywords
piperazine
hydroxypropyl
methyl
preparing
carboxylate compounds
Prior art date
Application number
DK019387A
Other languages
English (en)
Other versions
DK153879B (da
DK19387A (da
DK19387D0 (da
Inventor
Irving Maurice Goldman
Donald Ernest Kuhla
Constantine Sklavounds
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK19387A publication Critical patent/DK19387A/da
Publication of DK19387D0 publication Critical patent/DK19387D0/da
Publication of DK153879B publication Critical patent/DK153879B/da
Application granted granted Critical
Publication of DK153879C publication Critical patent/DK153879C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205Radicals derived from carbonic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
DK019387A 1978-05-18 1987-01-15 Fremgangsmaade til fremstilling af 2'-methyl-2'-hydroxypropyl-piperazin-1-carboxylatforbindelser DK153879C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90708278A 1978-05-18 1978-05-18
US90708278 1978-05-18

Publications (4)

Publication Number Publication Date
DK19387A DK19387A (da) 1987-01-15
DK19387D0 DK19387D0 (da) 1987-01-15
DK153879B DK153879B (da) 1988-09-19
DK153879C true DK153879C (da) 1989-02-06

Family

ID=25423490

Family Applications (6)

Application Number Title Priority Date Filing Date
DK095979A DK153878C (da) 1978-05-18 1979-03-08 Fremgangsmaade til fremstilling af 2'-methyl-2'-hydroxy-propyl-piperazin-1-carboxylatforbindelser
DK019587A DK153880C (da) 1978-05-18 1987-01-15 Fremgangsmaade til fremstilling af 2'-methyl-2'-hydroxy-propyl-piperazin-1-carboxylat
DK019487A DK153840C (da) 1978-05-18 1987-01-15 Fremgangsmaade til fremstilling af 2'-methyl-2'-hydroxypropyl-piperazin-1-carboxylatforbindelser
DK019387A DK153879C (da) 1978-05-18 1987-01-15 Fremgangsmaade til fremstilling af 2'-methyl-2'-hydroxypropyl-piperazin-1-carboxylatforbindelser
DK019687A DK153881C (da) 1978-05-18 1987-01-15 Fremgangsmaade til fremstilling af 2'-methyl-2'hydroxy-propyl-piperazin-1-carboxylat
DK019287A DK19287D0 (da) 1978-05-18 1987-01-15 Fremgangsmaade til fremstilling af 2-methyl-2-hydroxypropyl-piperazin-1-carboxylatforbindelser

Family Applications Before (3)

Application Number Title Priority Date Filing Date
DK095979A DK153878C (da) 1978-05-18 1979-03-08 Fremgangsmaade til fremstilling af 2'-methyl-2'-hydroxy-propyl-piperazin-1-carboxylatforbindelser
DK019587A DK153880C (da) 1978-05-18 1987-01-15 Fremgangsmaade til fremstilling af 2'-methyl-2'-hydroxy-propyl-piperazin-1-carboxylat
DK019487A DK153840C (da) 1978-05-18 1987-01-15 Fremgangsmaade til fremstilling af 2'-methyl-2'-hydroxypropyl-piperazin-1-carboxylatforbindelser

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK019687A DK153881C (da) 1978-05-18 1987-01-15 Fremgangsmaade til fremstilling af 2'-methyl-2'hydroxy-propyl-piperazin-1-carboxylat
DK019287A DK19287D0 (da) 1978-05-18 1987-01-15 Fremgangsmaade til fremstilling af 2-methyl-2-hydroxypropyl-piperazin-1-carboxylatforbindelser

Country Status (42)

Country Link
US (1) US4550164A (da)
JP (1) JPS5946512B2 (da)
AR (1) AR220195A1 (da)
AT (1) AT375357B (da)
AU (1) AU510441B2 (da)
BE (1) BE876311A (da)
BG (1) BG31228A3 (da)
CA (1) CA1097643A (da)
CH (1) CH638796A5 (da)
CS (1) CS236762B2 (da)
DD (1) DD143428A5 (da)
DE (1) DE2919799C2 (da)
DK (6) DK153878C (da)
EG (1) EG13904A (da)
ES (1) ES480669A1 (da)
FI (1) FI64588C (da)
FR (2) FR2432022A1 (da)
GB (1) GB2021107B (da)
GR (1) GR72720B (da)
GT (1) GT197957903A (da)
HK (1) HK13484A (da)
HU (1) HU180282B (da)
IE (1) IE48048B1 (da)
IL (1) IL57295A (da)
IN (1) IN151190B (da)
IT (1) IT1114238B (da)
KE (1) KE3353A (da)
LU (1) LU81271A1 (da)
MX (1) MX6289E (da)
MY (1) MY8500095A (da)
NL (1) NL183190C (da)
NO (1) NO151156C (da)
NZ (1) NZ190473A (da)
PH (2) PH15546A (da)
PL (1) PL118664B1 (da)
PT (1) PT69623A (da)
RO (1) RO76812A (da)
SE (1) SE446183B (da)
SG (1) SG65783G (da)
SU (1) SU1007557A3 (da)
YU (1) YU41633B (da)
ZA (1) ZA792391B (da)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1096204A (fr) * 1949-06-30 1955-06-16 Saint Gobain Procédé de fabrication d'uréthanes dérivées des glycols
FR62617E (fr) * 1951-06-29 1955-06-15 Saint Gobain Procédé de fabrication d'uréthanes dérivées des glycols
DE1249852B (de) * 1964-10-07 1967-09-14 Dr Christian Brunnengraber Che mische Fabrik &. Co mbH Lübeck Verfahren zur Herstellung von Carbamm saureestern von a Glycermathern
US3703538A (en) * 1969-02-03 1972-11-21 Jefferson Chem Co Inc Production of anhydrous beta-hydroxy-alkyl carbamates
US3935213A (en) * 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives

Also Published As

Publication number Publication date
DK153840B (da) 1988-09-12
DE2919799C2 (de) 1985-12-05
IT7922759A0 (it) 1979-05-17
SE7904313L (sv) 1979-11-19
HU180282B (en) 1983-02-28
IL57295A (en) 1982-01-31
GT197957903A (es) 1980-11-07
HK13484A (en) 1984-02-24
LU81271A1 (fr) 1979-12-07
SE446183B (sv) 1986-08-18
GB2021107B (en) 1982-07-28
DK153880C (da) 1989-02-06
FR2429788A1 (fr) 1980-01-25
DK153878B (da) 1988-09-19
DK153878C (da) 1989-02-06
DK19287A (da) 1987-01-15
ATA366579A (de) 1983-12-15
DK95979A (da) 1979-11-19
PL118664B1 (en) 1981-10-31
CH638796A5 (fr) 1983-10-14
FR2429788B1 (da) 1982-04-16
PL215383A1 (da) 1980-08-11
CS236762B2 (en) 1985-05-15
DK19587A (da) 1987-01-15
MY8500095A (en) 1985-12-31
GB2021107A (en) 1979-11-28
YU41633B (en) 1987-12-31
SU1007557A3 (ru) 1983-03-23
YU113979A (en) 1983-02-28
MX6289E (es) 1985-03-18
IN151190B (da) 1983-03-05
SG65783G (en) 1984-07-27
AT375357B (de) 1984-07-25
FI791579A (fi) 1979-11-19
US4550164A (en) 1985-10-29
IE790962L (en) 1979-11-18
DK153879B (da) 1988-09-19
AR220195A1 (es) 1980-10-15
DK153880B (da) 1988-09-19
CA1097643A (en) 1981-03-17
AU510441B2 (en) 1980-06-26
NO151156C (no) 1985-02-20
DK19287D0 (da) 1987-01-15
JPS54151991A (en) 1979-11-29
NO151156B (no) 1984-11-12
ES480669A1 (es) 1980-05-16
DK19687D0 (da) 1987-01-15
NL183190C (nl) 1988-08-16
DK19487A (da) 1987-01-15
DE2919799A1 (de) 1979-11-22
IE48048B1 (en) 1984-09-05
DK19587D0 (da) 1987-01-15
DK19687A (da) 1987-01-15
DK153881C (da) 1989-02-06
GR72720B (da) 1983-12-01
DD143428A5 (de) 1980-08-20
DK153840C (da) 1989-01-30
FR2432022A1 (fr) 1980-02-22
RO76812A (ro) 1981-05-30
PT69623A (en) 1979-06-01
PH15546A (en) 1983-02-09
NZ190473A (en) 1981-01-23
IT1114238B (it) 1986-01-27
AU4710279A (en) 1979-11-22
NL7903892A (nl) 1979-11-20
PH16236A (en) 1983-08-11
KE3353A (en) 1983-12-16
EG13904A (en) 1983-12-31
NO791641L (no) 1979-11-20
BE876311A (fr) 1979-11-19
FR2432022B1 (da) 1983-07-08
FI64588C (fi) 1983-12-12
DK19487D0 (da) 1987-01-15
ZA792391B (en) 1980-05-28
JPS5946512B2 (ja) 1984-11-13
NL183190B (nl) 1988-03-16
BG31228A3 (en) 1981-11-16
DK19387A (da) 1987-01-15
DK19387D0 (da) 1987-01-15
IL57295A0 (en) 1979-09-30
FI64588B (fi) 1983-08-31
DK153881B (da) 1988-09-19

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