DK1482938T3 - Farmaceutisk præparat af en PDE4 eller en PDE3/4 inhibitor og en histaminreceptorantagonist - Google Patents
Farmaceutisk præparat af en PDE4 eller en PDE3/4 inhibitor og en histaminreceptorantagonistInfo
- Publication number
- DK1482938T3 DK1482938T3 DK03708130T DK03708130T DK1482938T3 DK 1482938 T3 DK1482938 T3 DK 1482938T3 DK 03708130 T DK03708130 T DK 03708130T DK 03708130 T DK03708130 T DK 03708130T DK 1482938 T3 DK1482938 T3 DK 1482938T3
- Authority
- DK
- Denmark
- Prior art keywords
- pde3
- pde4
- inhibitor
- receptor antagonist
- pharmaceutical preparation
- Prior art date
Links
- 101100296720 Dictyostelium discoideum Pde4 gene Proteins 0.000 title 1
- 101100135868 Dictyostelium discoideum pde3 gene Proteins 0.000 title 1
- 229940122236 Histamine receptor antagonist Drugs 0.000 title 1
- 101100082610 Plasmodium falciparum (isolate 3D7) PDEdelta gene Proteins 0.000 title 1
- 239000000739 antihistaminic agent Substances 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/423—Oxazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4425—Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02004987 | 2002-03-06 | ||
| PCT/EP2003/001876 WO2003074055A1 (en) | 2002-03-06 | 2003-02-25 | Pharmaceutical composition of a pde4 or a pde3/4 inhibitor and a histamine receptor antagonist |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1482938T3 true DK1482938T3 (da) | 2007-12-03 |
Family
ID=27771841
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03708130T DK1482938T3 (da) | 2002-03-06 | 2003-02-25 | Farmaceutisk præparat af en PDE4 eller en PDE3/4 inhibitor og en histaminreceptorantagonist |
| DK07112823.5T DK1849468T3 (da) | 2002-03-06 | 2003-02-25 | Farmaceutisk sammensætning omfattende roflumilast og levocetirizin |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07112823.5T DK1849468T3 (da) | 2002-03-06 | 2003-02-25 | Farmaceutisk sammensætning omfattende roflumilast og levocetirizin |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US20050112069A1 (enExample) |
| EP (2) | EP1849468B1 (enExample) |
| JP (1) | JP5150034B2 (enExample) |
| KR (1) | KR20040095255A (enExample) |
| CN (1) | CN101257904A (enExample) |
| AR (1) | AR038858A1 (enExample) |
| AT (1) | ATE369134T1 (enExample) |
| AU (1) | AU2003212268B2 (enExample) |
| BR (1) | BR0308220A (enExample) |
| CA (1) | CA2478612C (enExample) |
| CO (1) | CO5611148A2 (enExample) |
| CY (2) | CY1106927T1 (enExample) |
| DE (1) | DE60315426T2 (enExample) |
| DK (2) | DK1482938T3 (enExample) |
| EA (2) | EA010886B1 (enExample) |
| ES (2) | ES2291618T3 (enExample) |
| HR (1) | HRP20040909B1 (enExample) |
| IL (1) | IL163336A (enExample) |
| IS (2) | IS2536B (enExample) |
| MX (1) | MXPA04008460A (enExample) |
| NO (1) | NO335254B1 (enExample) |
| NZ (1) | NZ535611A (enExample) |
| PL (1) | PL211574B1 (enExample) |
| PT (2) | PT1849468E (enExample) |
| RS (1) | RS51018B (enExample) |
| SG (1) | SG160197A1 (enExample) |
| SI (2) | SI1482938T1 (enExample) |
| TW (1) | TWI347845B (enExample) |
| UA (1) | UA80117C2 (enExample) |
| WO (1) | WO2003074055A1 (enExample) |
| ZA (1) | ZA200407104B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8067433B2 (en) * | 2005-11-09 | 2011-11-29 | Zalicus Inc. | Methods, compositions, and kits for the treatment of ophthalmic disorders |
| EP2091538B1 (en) * | 2006-12-20 | 2010-03-03 | Glaxo Group Limited | 4-benzyl-1(2h)-phthalazinones as h1 receptor antagonists |
| US20090182035A1 (en) * | 2007-04-11 | 2009-07-16 | Alcon Research, Ltd. | Use of a combination of olopatadine and cilomilast to treat non-infectious rhinitis and allergic conjunctivitis |
| US20080254029A1 (en) * | 2007-04-11 | 2008-10-16 | Alcon Research, Ltd. | Use of an Inhibitor of TNFa Plus an Antihistamine to Treat Allergic Rhinitis and Allergic Conjunctivitis |
| WO2009067597A1 (en) * | 2007-11-21 | 2009-05-28 | Decode Genetics Ehf | 4- (or 5-) substituted catechol derivatives |
| KR20090061972A (ko) * | 2007-12-12 | 2009-06-17 | 한미약품 주식회사 | 베포타스틴 ｐ-톨루엔술폰산염의 결정형, 이의 제조방법 및이를 포함하는 약학 조성물 |
| KR101852222B1 (ko) | 2011-02-07 | 2018-04-25 | 에스씨아이팜 에스에이알엘 | 낭포성 섬유증의 치료를 위한 신규 조성물 |
| KR102226833B1 (ko) * | 2013-06-28 | 2021-03-12 | 한미약품 주식회사 | 레보세티리진 및 몬테루카스트를 포함하는 안정성이 개선된 복합 과립 제형 |
| JP2017525721A (ja) * | 2014-08-26 | 2017-09-07 | ファンダシオン パラ ラ インベスティガシオン メディカ アプリカダＦｕｎｄａｃｉｏｎ Ｐａｒａ Ｌａ Ｉｎｖｅｓｔｉｇａｓｉｏｎ Ｍｅｄｉｃａ Ａｐｌｉｃａｄａ | 認知欠損または認知障害に伴って進行する神経障害のおよび神経変性疾患の処置および予防のための製品 |
| BR112017007194B1 (pt) | 2014-10-09 | 2023-11-07 | Guangdong Raynovent Biotech Co., Ltd | Compostos de hidroxil purina e uso dos mesmos |
| CN109956947A (zh) * | 2017-12-25 | 2019-07-02 | 江苏恒瑞医药股份有限公司 | 一种cns抑制剂的新晶型、制备方法及用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2847693A1 (de) * | 1978-11-03 | 1980-05-22 | Hoechst Ag | Verfahren zur herstellung von pyrimido-(6,1-a)-isochinolin-2-onen |
| AU650953B2 (en) | 1991-03-21 | 1994-07-07 | Novartis Ag | Inhaler |
| HU220041B (hu) * | 1993-07-02 | 2001-10-28 | Byk Gulden Lomberg Chemische Fabrik Gmbh. | Fluor-alkoxi-helyettesített benzamidszármazékok, eljárás előállításukra és ezeket a vegyületeket tartalmazó gyógyászati készítmények |
| US5900421A (en) * | 1997-02-11 | 1999-05-04 | Sepracor Inc. | Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine |
| US5990147A (en) * | 1997-11-07 | 1999-11-23 | Schering Corporation | H3 receptor ligands of the phenyl-alkyl-imidazoles type |
| BR9804993A (pt) * | 1998-11-10 | 2000-06-06 | Panacea Biotec Ltd | Composição antialérgica e antiinflamatória |
| US6174878B1 (en) * | 1999-08-31 | 2001-01-16 | Alcon Laboratories, Inc. | Topical use of kappa opioid agonists to treat otic pain |
| EP1244654A1 (en) * | 1999-10-25 | 2002-10-02 | ALTANA Pharma AG | Tetrahydrothiopy ranphthalazinone derivatives as pde4 inhibitors |
| US7585847B2 (en) * | 2000-02-03 | 2009-09-08 | Coley Pharmaceutical Group, Inc. | Immunostimulatory nucleic acids for the treatment of asthma and allergy |
| GB0115181D0 (en) * | 2001-06-20 | 2001-08-15 | Glaxo Group Ltd | Novel use |
-
2003
- 2003-02-20 TW TW092103525A patent/TWI347845B/zh not_active IP Right Cessation
- 2003-02-25 CA CA2478612A patent/CA2478612C/en not_active Expired - Fee Related
- 2003-02-25 HR HR20040909 patent/HRP20040909B1/xx not_active IP Right Cessation
- 2003-02-25 EA EA200601592A patent/EA010886B1/ru not_active IP Right Cessation
- 2003-02-25 ES ES03708130T patent/ES2291618T3/es not_active Expired - Lifetime
- 2003-02-25 DE DE60315426T patent/DE60315426T2/de not_active Expired - Lifetime
- 2003-02-25 SG SG200606154-3A patent/SG160197A1/en unknown
- 2003-02-25 MX MXPA04008460A patent/MXPA04008460A/es active IP Right Grant
- 2003-02-25 EA EA200401137A patent/EA007903B1/ru not_active IP Right Cessation
- 2003-02-25 JP JP2003572572A patent/JP5150034B2/ja not_active Expired - Fee Related
- 2003-02-25 PL PL371056A patent/PL211574B1/pl unknown
- 2003-02-25 EP EP07112823A patent/EP1849468B1/en not_active Expired - Lifetime
- 2003-02-25 US US10/506,875 patent/US20050112069A1/en not_active Abandoned
- 2003-02-25 SI SI200330970T patent/SI1482938T1/sl unknown
- 2003-02-25 DK DK03708130T patent/DK1482938T3/da active
- 2003-02-25 ES ES07112823T patent/ES2400670T3/es not_active Expired - Lifetime
- 2003-02-25 DK DK07112823.5T patent/DK1849468T3/da active
- 2003-02-25 NZ NZ535611A patent/NZ535611A/xx not_active IP Right Cessation
- 2003-02-25 CN CNA038053349A patent/CN101257904A/zh active Pending
- 2003-02-25 KR KR10-2004-7013742A patent/KR20040095255A/ko not_active Ceased
- 2003-02-25 WO PCT/EP2003/001876 patent/WO2003074055A1/en not_active Ceased
- 2003-02-25 AU AU2003212268A patent/AU2003212268B2/en not_active Ceased
- 2003-02-25 EP EP03708130A patent/EP1482938B1/en not_active Expired - Lifetime
- 2003-02-25 BR BR0308220-2A patent/BR0308220A/pt not_active Application Discontinuation
- 2003-02-25 UA UA20041008055A patent/UA80117C2/uk unknown
- 2003-02-25 AT AT03708130T patent/ATE369134T1/de active
- 2003-02-25 PT PT71128235T patent/PT1849468E/pt unknown
- 2003-02-25 PT PT03708130T patent/PT1482938E/pt unknown
- 2003-02-25 RS YUP-780/04A patent/RS51018B/sr unknown
- 2003-02-25 SI SI200332245T patent/SI1849468T1/sl unknown
- 2003-02-27 AR ARP030100646A patent/AR038858A1/es unknown
-
2004
- 2004-08-03 IL IL163336A patent/IL163336A/en not_active IP Right Cessation
- 2004-09-03 IS IS7438A patent/IS2536B/is unknown
- 2004-09-03 CO CO04086713A patent/CO5611148A2/es active IP Right Grant
- 2004-09-06 ZA ZA200407104A patent/ZA200407104B/en unknown
- 2004-10-06 NO NO20044230A patent/NO335254B1/no not_active IP Right Cessation
-
2007
- 2007-10-11 CY CY20071101307T patent/CY1106927T1/el unknown
-
2008
- 2008-09-04 IS IS8760A patent/IS8760A/is unknown
-
2013
- 2013-02-21 CY CY20131100163T patent/CY1113894T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IS8760A (is) | Lyfjablanda úr pde4 eða pde3/4 tálma og histamínviðtakamótlyfi | |
| DE60103974D1 (de) | Gyrase-inhibitoren und ihre verwendung | |
| NO20040469L (no) | Heterocykliske forbindelser samt fremstilling og anvendelse derav | |
| DK1455756T3 (da) | Farmaceutisk nanopartikelformig sammensætning af en Tachykinin-receptor-antagonist | |
| DK1122244T3 (da) | Uracilforbindelser og anvendelse deraf | |
| DK1411923T3 (da) | Farmaceutisk sammensætning af amlodipin og atorvastatin | |
| DE60208661D1 (de) | Diaminothiazole und ihre verwendung als cyclinabhängige kinase inhibitoren | |
| DK1527067T3 (da) | 4-Trifluormethylpyrazolylsubstituerede pyridiner og pyrimidiner | |
| DE60234167D1 (de) | Bipiperidin-derivate und ihre verwendung als inhibitoren der chemokinrezeptoren | |
| AR028281A1 (es) | Derivados de 2-(arilalquilamino) pirimidona y derivados de 2-(heteroaroarilalquilamino) pirimidona | |
| DK1335906T3 (da) | Pyrimidinderivater og anvendelse deraf som neuropeptid Y-receptorligander | |
| ITMI20021247A1 (it) | Antagonisti basici non peptidici della bradichinina e loro impiego informulazioni farmaceutiche | |
| DK1106607T3 (da) | Uracilforbindelser og anvendelse deraf | |
| NO20031997L (no) | CRF-reseptor-antagonist og metoder relatert dertil | |
| PT1448566E (pt) | Antagonistas do receptor quimioquina e metodos de utilizacao do mesmo | |
| EP1461450A4 (en) | T-BET COMPOSITIONS AND METHOD OF USE THEREOF | |
| NO20033223D0 (no) | Histamin-reseptor antagonister | |
| PT1392670E (pt) | Derivados substituidos de c-furan-2-il-metilamina e c-tiofen-2-il-metilamina | |
| DE60203934D1 (de) | Pharmazeutische kombination von adenosine a-2a und beta-2-adrenergen rezeptoren agonisten | |
| DK1440067T3 (da) | N-formyl-derivater af paroxetin | |
| DE60011801D1 (de) | Benzoxa- und benzthiazolylsulfamate sowie ihre verwendung als steroid-sulfataseinhibitoren | |
| AU2003248853A8 (en) | Detection of drug-resistant human immunodeficiency virus | |
| FR2861103B1 (fr) | Dispositif anti-soulevement et de maintien d'elements d'ouvrage d'art | |
| EE200300075A (et) | Angiotensiin II antagonistide ja ACE inhibiitorite farmatseutiline kombinatsioon | |
| SE0203540D0 (sv) | Use of an inhibilor or antagonist against lissue factor |