DK1468014T3 - Sammensætninger og fremgangsmåder til WT1-specifik immunterapi - Google Patents
Sammensætninger og fremgangsmåder til WT1-specifik immunterapiInfo
- Publication number
- DK1468014T3 DK1468014T3 DK02797061T DK02797061T DK1468014T3 DK 1468014 T3 DK1468014 T3 DK 1468014T3 DK 02797061 T DK02797061 T DK 02797061T DK 02797061 T DK02797061 T DK 02797061T DK 1468014 T3 DK1468014 T3 DK 1468014T3
- Authority
- DK
- Denmark
- Prior art keywords
- compositions
- polypeptide
- methods
- specific immunotherapy
- presenting
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 238000009169 immunotherapy Methods 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 210000000612 antigen-presenting cell Anatomy 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
- 230000003211 malignant effect Effects 0.000 abstract 1
- 206010061289 metastatic neoplasm Diseases 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/002,603 US7901693B2 (en) | 1998-09-30 | 2001-10-30 | Compositions and methods for WT1 specific immunotherapy |
US10/125,635 US20030039635A1 (en) | 1998-09-30 | 2002-04-16 | Compositions and methods for WT1 specific immunotherapy |
US10/195,835 US7655249B2 (en) | 1998-09-30 | 2002-07-12 | Compositions and methods for WT1 specific immunotherapy |
US10/244,830 US20030235557A1 (en) | 1998-09-30 | 2002-09-16 | Compositions and methods for WT1 specific immunotherapy |
PCT/US2002/035194 WO2003037060A2 (en) | 2001-10-30 | 2002-10-30 | Compositions and methods for wt1 specific immunotherapy |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1468014T3 true DK1468014T3 (da) | 2009-08-10 |
Family
ID=27485189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02797061T DK1468014T3 (da) | 2001-10-30 | 2002-10-30 | Sammensætninger og fremgangsmåder til WT1-specifik immunterapi |
Country Status (14)
Country | Link |
---|---|
US (1) | US20030235557A1 (da) |
EP (2) | EP2172476A3 (da) |
JP (1) | JP4391232B2 (da) |
KR (1) | KR100970854B1 (da) |
CN (1) | CN100471868C (da) |
AT (1) | ATE429442T1 (da) |
AU (1) | AU2002361584B2 (da) |
CA (1) | CA2465303C (da) |
CY (1) | CY1111002T1 (da) |
DE (1) | DE60232102D1 (da) |
DK (1) | DK1468014T3 (da) |
ES (1) | ES2326311T3 (da) |
NZ (2) | NZ533220A (da) |
WO (1) | WO2003037060A2 (da) |
Families Citing this family (53)
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BRPI9912663B8 (pt) * | 1998-07-31 | 2021-07-06 | Int Inst Cancer Immunology Inc | vacina contra cáncer e polipeptìdeo. |
US7901693B2 (en) | 1998-09-30 | 2011-03-08 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7655249B2 (en) | 1998-09-30 | 2010-02-02 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7329410B1 (en) | 1998-09-30 | 2008-02-12 | Corixa Corporation | Compositions and method for WT1 specific immunotherapy |
TWI318630B (en) * | 2001-03-22 | 2009-12-21 | Int Inst Cancer Immunology Inc | Wt1 modified peptide |
US7553494B2 (en) | 2001-08-24 | 2009-06-30 | Corixa Corporation | WT1 fusion proteins |
KR101431312B1 (ko) | 2003-06-27 | 2014-08-20 | 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 | Wt1 백신 적응 환자의 선택 방법 |
WO2005026370A2 (en) * | 2003-09-05 | 2005-03-24 | Sanofi Pasteur Limted. | Multi-antigen vectors for melanoma |
ES2378264T3 (es) | 2003-11-05 | 2012-04-10 | International Institute Of Cancer Immunology, Inc. | Péptido antigénico de unión a HLA-DR derivado de WT1 |
US7488718B2 (en) * | 2003-12-01 | 2009-02-10 | Sloan Kettering Institue For Cancer Research | Synthetic HLA binding peptide analogues and uses thereof |
EP1720565A1 (en) * | 2004-03-04 | 2006-11-15 | Corixa Corporation | Co-encapsulated wt1 polypeptide and immunostimulant microsphere formulations and methods thereof |
ATE462003T1 (de) * | 2004-03-31 | 2010-04-15 | Int Inst Cancer Immunology Inc | Aus wt1 stammende krebsantigenpeptide |
EP1657250A1 (en) * | 2004-11-11 | 2006-05-17 | Charité - Universitätsmedizin Berlin | HLA-A *01-binding T-cell epitope of WT1 |
EP1951281B1 (en) | 2005-10-17 | 2015-04-15 | Sloan Kettering Institute For Cancer Research | Wt1 hla class ii-binding peptides and compositions and methods comprising same |
PL1988163T3 (pl) | 2006-02-22 | 2012-11-30 | Int Inst Cancer Immunology Inc | Ograniczony do hla-a*3303 peptyd wt1 i zawierająca go kompozycja farmaceutyczna |
EP3117836A1 (en) | 2006-04-10 | 2017-01-18 | Sloan Kettering Institute For Cancer Research | Immunogenic wt-1 peptides and uses thereof |
CN100460013C (zh) * | 2006-09-05 | 2009-02-11 | 重庆康卫生物科技有限公司 | 口服重组幽门螺杆菌疫苗及其制备方法 |
AU2012227350C1 (en) * | 2006-12-28 | 2015-11-12 | International Institute Of Cancer Immunology, Inc. | HLA-A*1101-Restricted WT1 peptide and pharmaceutical composition comprising the same |
DK2341142T3 (da) * | 2006-12-28 | 2014-12-08 | Int Inst Cancer Immunology Inc | HLA-A*1101-begrænset-WT1-peptid og farmaceutisk sammensætning omfattende dette |
CN103103246B (zh) * | 2007-02-27 | 2018-05-01 | 株式会社癌免疫研究所 | 活化辅助t细胞的方法以及用于该方法的组合物 |
EP2116596A4 (en) | 2007-03-05 | 2010-04-07 | Int Inst Cancer Immunology Inc | L-CELL RECEPTOR GENE SPECIFIC TO A CANCER ANTIGEN, PEPTIDE CODED BY THE GENE AND THEIR USE |
KR20110091817A (ko) * | 2007-05-24 | 2011-08-12 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 동결건조 항원 조성물 |
AU2008290049B2 (en) * | 2007-08-20 | 2013-08-29 | Oncotherapy Science, Inc. | FOXM1 peptide and medicinal agent comprising the same |
WO2009066462A1 (ja) * | 2007-11-20 | 2009-05-28 | Nec Corporation | 細胞傷害性t細胞の誘導方法、細胞傷害性t細胞の誘導剤、およびそれを用いた医薬組成物およびワクチン |
TWI469791B (zh) | 2009-02-18 | 2015-01-21 | Oncotherapy Science Inc | Foxm1胜肽以及含此胜肽之疫苗 |
AR076349A1 (es) * | 2009-04-23 | 2011-06-01 | Int Inst Cancer Immunology Inc | Peptido auxiliar del antigeno del cancer |
US8685656B2 (en) * | 2009-09-29 | 2014-04-01 | The Trustees Of The University Of Pennsylvania | Methods for diagnosing and treating encephalitis or epilepsy |
WO2012046730A1 (ja) | 2010-10-05 | 2012-04-12 | 国立大学法人大阪大学 | ヘルパーt細胞の活性化方法 |
CN102161998B (zh) * | 2011-01-14 | 2013-01-09 | 中国人民解放军军事医学科学院附属医院 | 基于b7-1-pe40kdel外毒素融合基因的dna疫苗及其用途 |
CA2839663A1 (en) | 2011-06-28 | 2013-01-03 | International Institute Of Cancer Immunology, Inc. | Receptor gene for peptide cancer antigen-specific t cell |
BR112014002747A2 (pt) * | 2011-09-14 | 2020-10-27 | International Institute Of Cancer Immunology, Inc | método para medir um anticorpo anti-wt1 |
CN104684577B (zh) | 2012-01-13 | 2018-05-08 | 纪念斯隆凯特林癌症中心 | 免疫原性wt-1肽及其使用方法 |
WO2014093897A1 (en) * | 2012-12-13 | 2014-06-19 | The Trustees Of The University Of Pennsylvania | Wt1 vaccine |
EP2933261B1 (en) | 2012-12-17 | 2020-06-10 | Otsuka Pharmaceutical Co., Ltd. | Method for activating helper t cell |
US10815273B2 (en) | 2013-01-15 | 2020-10-27 | Memorial Sloan Kettering Cancer Center | Immunogenic WT-1 peptides and methods of use thereof |
PT2945647T (pt) * | 2013-01-15 | 2020-11-26 | Memorial Sloan Kettering Cancer Center | Péptidos imunogénicos wt-1 e métodos de uso dos mesmos |
CA2840988A1 (en) | 2013-02-05 | 2014-08-05 | Nitto Denko Corporation | Wt1 peptide cancer vaccine composition for mucosal administration |
KR20160007579A (ko) * | 2013-05-13 | 2016-01-20 | 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 | 면역요법의 임상 효과의 예측법 |
CN110511960B (zh) * | 2013-07-15 | 2023-05-23 | 美国卫生和人力服务部 | 抗人乳头瘤病毒16 e6 t细胞受体 |
WO2015129790A1 (ja) | 2014-02-26 | 2015-09-03 | 株式会社バイオイミュランス | Wt1抗原性ポリペプチド、及び該ポリペプチドを含む抗腫瘍剤 |
US10682400B2 (en) | 2014-04-30 | 2020-06-16 | President And Fellows Of Harvard College | Combination vaccine devices and methods of killing cancer cells |
MA43283B1 (fr) | 2015-11-20 | 2022-08-31 | Memorial Sloan Kettering Cancer Center | Composition pour le traitement du cancer |
CN105254760B (zh) * | 2015-11-21 | 2018-08-17 | 福州迈新生物技术开发有限公司 | 一株分泌抗wt1蛋白的单克隆抗体及其应用 |
CN109072197A (zh) | 2016-02-06 | 2018-12-21 | 哈佛学院校长同事会 | 重塑造血巢以重建免疫 |
US11555177B2 (en) | 2016-07-13 | 2023-01-17 | President And Fellows Of Harvard College | Antigen-presenting cell-mimetic scaffolds and methods for making and using the same |
BR112019005633A8 (pt) * | 2016-09-23 | 2023-04-11 | Hutchinson Fred Cancer Res | Tcrs específicos para antigênio ha-1 de histocompatibilidade (h) menor e usos dos mesmos |
US20200016255A1 (en) | 2016-11-30 | 2020-01-16 | Sumitomo Dainippon Pharma Co., Ltd. | Wt1 helper peptides and combinations of wt1 helper peptide and conjugate of cancer antigen peptides |
JPWO2018181648A1 (ja) | 2017-03-30 | 2020-02-13 | 大日本住友製薬株式会社 | Wt1癌抗原ペプチドおよびこれを含むペプチドコンジュゲート体 |
WO2018227205A1 (en) * | 2017-06-09 | 2018-12-13 | President And Fellows Of Harvard College | Compositions for inducing an immune response |
CA3113212A1 (en) | 2018-09-28 | 2020-04-02 | Sumitomo Dainippon Pharma Co., Ltd. | Injectable composition |
WO2021230247A1 (ja) | 2020-05-12 | 2021-11-18 | 大日本住友製薬株式会社 | 癌を処置するための医薬組成物 |
JPWO2023017836A1 (da) | 2021-08-12 | 2023-02-16 | ||
CN113730562B (zh) * | 2021-09-10 | 2024-06-04 | 中国人民解放军陆军军医大学 | 以壳聚糖修饰plga的wt1多肽纳米粒疫苗及其制备方法和应用 |
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- 2002-09-16 US US10/244,830 patent/US20030235557A1/en not_active Abandoned
- 2002-10-30 EP EP09153790A patent/EP2172476A3/en not_active Withdrawn
- 2002-10-30 DE DE60232102T patent/DE60232102D1/de not_active Expired - Lifetime
- 2002-10-30 AU AU2002361584A patent/AU2002361584B2/en not_active Ceased
- 2002-10-30 DK DK02797061T patent/DK1468014T3/da active
- 2002-10-30 ES ES02797061T patent/ES2326311T3/es not_active Expired - Lifetime
- 2002-10-30 NZ NZ533220A patent/NZ533220A/en not_active IP Right Cessation
- 2002-10-30 EP EP02797061A patent/EP1468014B1/en not_active Expired - Lifetime
- 2002-10-30 CA CA2465303A patent/CA2465303C/en not_active Expired - Fee Related
- 2002-10-30 AT AT02797061T patent/ATE429442T1/de active
- 2002-10-30 CN CNB028264924A patent/CN100471868C/zh not_active Expired - Fee Related
- 2002-10-30 NZ NZ560858A patent/NZ560858A/en not_active IP Right Cessation
- 2002-10-30 KR KR1020047006659A patent/KR100970854B1/ko not_active IP Right Cessation
- 2002-10-30 JP JP2003539419A patent/JP4391232B2/ja not_active Expired - Fee Related
- 2002-10-30 WO PCT/US2002/035194 patent/WO2003037060A2/en active Application Filing
-
2009
- 2009-07-22 CY CY20091100785T patent/CY1111002T1/el unknown
Also Published As
Publication number | Publication date |
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WO2003037060A3 (en) | 2004-08-12 |
US20030235557A1 (en) | 2003-12-25 |
CA2465303A1 (en) | 2003-05-08 |
WO2003037060A2 (en) | 2003-05-08 |
EP1468014B1 (en) | 2009-04-22 |
CN1671733A (zh) | 2005-09-21 |
EP1468014A2 (en) | 2004-10-20 |
JP4391232B2 (ja) | 2009-12-24 |
NZ560858A (en) | 2009-06-26 |
DE60232102D1 (de) | 2009-06-04 |
EP1468014A4 (en) | 2006-05-17 |
CY1111002T1 (el) | 2015-06-11 |
EP2172476A2 (en) | 2010-04-07 |
AU2002361584B2 (en) | 2009-07-23 |
ATE429442T1 (de) | 2009-05-15 |
ES2326311T3 (es) | 2009-10-07 |
NZ533220A (en) | 2008-04-30 |
CN100471868C (zh) | 2009-03-25 |
EP2172476A3 (en) | 2010-06-23 |
KR20050042226A (ko) | 2005-05-06 |
CA2465303C (en) | 2011-09-13 |
KR100970854B1 (ko) | 2010-07-20 |
JP2005518192A (ja) | 2005-06-23 |
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