MA43283B1 - Composition pour le traitement du cancer - Google Patents
Composition pour le traitement du cancerInfo
- Publication number
- MA43283B1 MA43283B1 MA43283A MA43283A MA43283B1 MA 43283 B1 MA43283 B1 MA 43283B1 MA 43283 A MA43283 A MA 43283A MA 43283 A MA43283 A MA 43283A MA 43283 B1 MA43283 B1 MA 43283B1
- Authority
- MA
- Morocco
- Prior art keywords
- peptide
- cancer
- expressing
- administering
- induction
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 4
- 201000011510 cancer Diseases 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 7
- 230000028993 immune response Effects 0.000 abstract 2
- 230000006698 induction Effects 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 229940076838 Immune checkpoint inhibitor Drugs 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 abstract 1
- 229940124447 delivery agent Drugs 0.000 abstract 1
- 210000002865 immune cell Anatomy 0.000 abstract 1
- 239000012274 immune-checkpoint protein inhibitor Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001152—Transcription factors, e.g. SOX or c-MYC
- A61K39/001153—Wilms tumor 1 [WT1]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/80—Vaccine for a specifically defined cancer
- A61K2039/892—Reproductive system [uterus, ovaries, cervix, testes]
Abstract
L'invention concerne des procédés de traitement, de réduction de l'incidence des réponses immunitaires et de leur induction vis-à-vis d'un cancer exprimant wt1, par l'administration d'une combinaison d'au moins un peptide wt1, ou de lymphocytes t cytotoxiques (ctl) contre un cancer exprimant wt1, et d'au moins un inhibiteur de point de contrôle. Ledit ou les lesdits peptides wt1 peuvent être administrés au sujet par administration d'un ou de plusieurs agents au sujet entraînant l'apport d'un ou plusieurs peptides wt1 et l'induction d'une réponse immunitaire contre le cancer exprimant wt1. Des exemples de ces agents d'administration wt1 comprennent : (i) un peptide wt1 isolé, (ii) un acide nucléique codant pour le ou les peptides wt1, et (iii) une cellule immunitaire comprenant ou présentant le ou les peptides wt1 ou un acide nucléique codant pour le ou les peptides wt1.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562258134P | 2015-11-20 | 2015-11-20 | |
PCT/US2016/062865 WO2017087857A1 (fr) | 2015-11-20 | 2016-11-18 | Procédés et compositions pour le traitement du cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
MA43283A MA43283A (fr) | 2018-09-26 |
MA43283B1 true MA43283B1 (fr) | 2022-08-31 |
Family
ID=58717878
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA43283A MA43283B1 (fr) | 2015-11-20 | 2016-11-18 | Composition pour le traitement du cancer |
Country Status (19)
Country | Link |
---|---|
US (1) | US11033613B2 (fr) |
EP (2) | EP4130026A1 (fr) |
JP (3) | JP6991969B2 (fr) |
KR (1) | KR20180094922A (fr) |
CN (4) | CN116327903A (fr) |
AU (2) | AU2016356708B2 (fr) |
CA (1) | CA3005896A1 (fr) |
DK (1) | DK3377516T3 (fr) |
ES (1) | ES2926386T3 (fr) |
HR (1) | HRP20220994T1 (fr) |
HU (1) | HUE059694T2 (fr) |
LT (1) | LT3377516T (fr) |
MA (1) | MA43283B1 (fr) |
MD (1) | MD3377516T2 (fr) |
PL (1) | PL3377516T3 (fr) |
PT (1) | PT3377516T (fr) |
RS (1) | RS63561B1 (fr) |
SI (1) | SI3377516T1 (fr) |
WO (1) | WO2017087857A1 (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015109391A1 (fr) | 2014-01-24 | 2015-07-30 | Children's Hospital Of Eastern Ontario Research Institute Inc. | Polythérapie anticancéreuse à base de smc |
CN116327903A (zh) | 2015-11-20 | 2023-06-27 | 纪念斯隆凯特林癌症中心 | 用于治疗癌症的方法和组合物 |
US11505591B2 (en) | 2016-05-18 | 2022-11-22 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
AU2017283480A1 (en) | 2016-06-13 | 2019-01-24 | Torque Therapeutics, Inc. | Methods and compositions for promoting immune cell function |
KR20190082850A (ko) | 2016-11-30 | 2019-07-10 | 어드박시스, 인크. | 반복되는 암 돌연변이를 표적화하는 면역원 조성물 및 그것의 사용 방법 |
CN116970060A (zh) | 2016-12-22 | 2023-10-31 | 库尔生物制药有限公司 | T细胞调节性多聚体多肽及其使用方法 |
US11851471B2 (en) | 2017-01-09 | 2023-12-26 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
EP3596118A4 (fr) | 2017-03-15 | 2021-04-07 | Cue Biopharma, Inc. | Procédés pour moduler une réponse immunitaire |
WO2019006401A2 (fr) * | 2017-06-30 | 2019-01-03 | Advaxis, Inc. | Compositions immunogènes à base de listeria comprenant des antigènes de protéine tumorale de wilms hétéroclitique et procédés d'utilisation correspondants |
EP3678701A4 (fr) | 2017-09-05 | 2021-12-01 | Torque Therapeutics, Inc. | Compositions protéiques thérapeutiques et procédés de préparation et d'utilisation de celles-ci |
KR20200070405A (ko) * | 2017-11-08 | 2020-06-17 | 어드박시스, 인크. | 암 관련 단백질로부터의 면역원성 불규칙변화성 펩타이드 및 그것의 사용 방법 |
EP3737689A4 (fr) | 2018-01-09 | 2021-12-01 | Cue Biopharma, Inc. | Polypeptides multimères modulateurs de lymphocytes t et leurs procédés d'utilisation |
US20210047363A1 (en) * | 2018-03-06 | 2021-02-18 | The United States Of America,As Represented By The Secretary,Department Of Health And Human Services | 17-beta-hydroxywithanolides and use thereof in treating cancer |
KR20210073540A (ko) * | 2018-10-05 | 2021-06-18 | 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 | 양성 종양의 예방 또는 치료약 |
TW202039542A (zh) * | 2018-12-19 | 2020-11-01 | 美商庫爾生物製藥有限公司 | 多聚體t細胞調節多肽及其使用方法 |
KR20220010712A (ko) * | 2019-04-10 | 2022-01-26 | 에스엘에스지 리미티드 엘엘씨 | Wt1-양성 암을 치료하기 위한 다가 면역요법 조성물 및 사용 방법 |
EP4085130A4 (fr) | 2019-12-31 | 2024-04-10 | Elixirgen Therapeutics Inc | Administration transitoire basée sur la température d'acides nucléiques et de protéines à des cellules et des tissus |
CN115666542A (zh) * | 2020-04-07 | 2023-01-31 | 梅塔诺伊治疗公司 | 用于治疗上皮性卵巢癌的乙醇胺调配物 |
MX2022013208A (es) | 2020-05-12 | 2022-11-14 | Cue Biopharma Inc | Polipeptidos multimericos moduladores de linfocitos t y metodos de uso de estos. |
Family Cites Families (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
US5837249A (en) | 1985-04-19 | 1998-11-17 | The Wistar Institute | Method for generating an immunogenic T cell response protective against a virus |
AU1570292A (en) | 1991-02-07 | 1992-09-07 | Board Of Trustees Of The University Of Illinois, The | Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same |
WO1995004064A1 (fr) | 1993-07-29 | 1995-02-09 | The Regents Of The University Of California | Leurres polynucleotidiques inhibant l'expression du complexe d'histocompatibilite majeure ii, et applications |
US5643786A (en) | 1995-01-27 | 1997-07-01 | The United States Of America As Represented By The Department Of Health And Human Services | Method for isolating dendritic cells |
AU4932199A (en) | 1998-07-31 | 2000-02-21 | Haruo Sugiyama | Cancer antigens based on tumor suppressor gene wt1 product |
US20030235557A1 (en) | 1998-09-30 | 2003-12-25 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7115272B1 (en) | 1998-09-30 | 2006-10-03 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7901693B2 (en) | 1998-09-30 | 2011-03-08 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7655249B2 (en) | 1998-09-30 | 2010-02-02 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7144581B2 (en) | 2000-10-09 | 2006-12-05 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7063854B1 (en) | 1998-09-30 | 2006-06-20 | Corixa Corporation | Composition and methods for WTI specific immunotherapy |
MXPA01003344A (es) * | 1998-09-30 | 2004-04-21 | Corixa Corp | Composiciones y metodos para inmunoterapia especifica de wt1. |
US7329410B1 (en) | 1998-09-30 | 2008-02-12 | Corixa Corporation | Compositions and method for WT1 specific immunotherapy |
WO2001025273A2 (fr) | 1999-10-04 | 2001-04-12 | Corixa Corporation | Compositions et methodes se rapportant a une immunotherapie specifique a wt1 |
US20030082194A1 (en) | 2000-02-22 | 2003-05-01 | Alexander Gaiger | Compositions and methods for diagnosis and therapy of malignant mesothelioma |
US7553494B2 (en) | 2001-08-24 | 2009-06-30 | Corixa Corporation | WT1 fusion proteins |
WO2003106682A1 (fr) | 2002-06-12 | 2003-12-24 | 中外製薬株式会社 | Peptide antigene du cancer a restriction hla-a24 |
EP2343083B1 (fr) | 2003-06-27 | 2014-01-15 | International Institute of Cancer Immunology, Inc. | Procédé de diagnostic du cancer comprenant la mesure de la fréquence de cellules précurseurs des LTC de WTI |
US20080070835A1 (en) | 2003-11-05 | 2008-03-20 | International Institute Of Cancer Immunology, Inc | Hla-Dr-Binding Antigen Peptide Derived From Wt1 |
US20060127409A1 (en) | 2003-12-01 | 2006-06-15 | Scheinberg David A | Bcr-abl vaccines and methods of use thereof |
EP1708732B2 (fr) | 2003-12-01 | 2016-05-18 | Sloan-Kettering Institute For Cancer Research | Analogues peptidiques synthetiques de liaison a l'antigene histocompatibilite et leurs utilisations |
US8765687B2 (en) | 2005-10-17 | 2014-07-01 | Sloan Kettering Institute For Cancer Research | WT1 HLA class II-binding peptides and compositions and methods comprising same |
DE102006014261A1 (de) | 2006-03-28 | 2007-10-04 | Dr.Ing.H.C. F. Porsche Ag | Luftleitvorrichtung für ein Fahrzeug |
CA2645766A1 (fr) | 2006-04-10 | 2007-10-25 | Sloan Kettering Institute For Cancer Research | Peptides wt1 immunogenes et leurs methodes d'utilisation |
CA2881594C (fr) | 2007-12-05 | 2016-04-12 | International Institute Of Cancer Immunology, Inc. | Composition de vaccin contre le cancer |
US20110136141A1 (en) | 2009-12-03 | 2011-06-09 | Abbott Laboratories | Peptide reagents and method for inhibiting autoantibody antigen binding |
EP3520810A3 (fr) | 2012-01-13 | 2019-11-06 | Memorial Sloan-Kettering Cancer Center | Peptides wt1 immunogènes et ses utilisations |
US9919037B2 (en) | 2013-01-15 | 2018-03-20 | Memorial Sloan Kettering Cancer Center | Immunogenic WT-1 peptides and methods of use thereof |
CN103961702B (zh) * | 2013-02-05 | 2019-04-09 | 日东电工株式会社 | 粘膜给予用wt1肽癌症疫苗组合物 |
EP3607974A1 (fr) * | 2013-03-15 | 2020-02-12 | The Trustees of The University of Pennsylvania | Vaccins contre le cancer et procédés de traitement les utilisant |
MX2016005283A (es) | 2013-10-25 | 2017-02-20 | Pharmacyclics Llc | Tratamiento que utiliza inhibidores de tirosina quinasa de bruton e inmunoterapia. |
KR20160093012A (ko) | 2013-11-05 | 2016-08-05 | 코그네이트 바이오서비시즈, 인코포레이티드 | 암 치료를 위한 체크포인트 억제제 및 치료제의 배합물 |
WO2015103602A1 (fr) * | 2014-01-06 | 2015-07-09 | The Trustees Of The University Of Pennsylvania | Anticorps pd1 et pdl1 et combinaisons de vaccin et utilisation de celles-ci pour l'immunothérapie |
US9364523B2 (en) | 2014-03-17 | 2016-06-14 | Tapimmune Inc. | Chimeric nucleic acid molecule with non-AUG translation initiation sequences |
WO2016186177A1 (fr) | 2015-05-20 | 2016-11-24 | 大日本住友製薬株式会社 | Combinaison de peptide d'antigène wt1 et d'immunomodulateur |
CN116327903A (zh) | 2015-11-20 | 2023-06-27 | 纪念斯隆凯特林癌症中心 | 用于治疗癌症的方法和组合物 |
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2016
- 2016-11-18 CN CN202210863762.9A patent/CN116327903A/zh active Pending
- 2016-11-18 PL PL16867262.4T patent/PL3377516T3/pl unknown
- 2016-11-18 WO PCT/US2016/062865 patent/WO2017087857A1/fr active Application Filing
- 2016-11-18 ES ES16867262T patent/ES2926386T3/es active Active
- 2016-11-18 MA MA43283A patent/MA43283B1/fr unknown
- 2016-11-18 US US15/777,514 patent/US11033613B2/en active Active
- 2016-11-18 CN CN202210862167.3A patent/CN116327902A/zh active Pending
- 2016-11-18 JP JP2018526090A patent/JP6991969B2/ja active Active
- 2016-11-18 EP EP22175680.2A patent/EP4130026A1/fr active Pending
- 2016-11-18 HU HUE16867262A patent/HUE059694T2/hu unknown
- 2016-11-18 LT LTEPPCT/US2016/062865T patent/LT3377516T/lt unknown
- 2016-11-18 HR HRP20220994TT patent/HRP20220994T1/hr unknown
- 2016-11-18 AU AU2016356708A patent/AU2016356708B2/en active Active
- 2016-11-18 CA CA3005896A patent/CA3005896A1/fr active Pending
- 2016-11-18 PT PT168672624T patent/PT3377516T/pt unknown
- 2016-11-18 EP EP16867262.4A patent/EP3377516B1/fr active Active
- 2016-11-18 SI SI201631597T patent/SI3377516T1/sl unknown
- 2016-11-18 MD MDE20180934T patent/MD3377516T2/ro unknown
- 2016-11-18 RS RS20220828A patent/RS63561B1/sr unknown
- 2016-11-18 KR KR1020187017393A patent/KR20180094922A/ko active Search and Examination
- 2016-11-18 CN CN201680077975.1A patent/CN108431022B/zh active Active
- 2016-11-18 CN CN202210863749.3A patent/CN115920017A/zh active Pending
- 2016-11-18 DK DK16867262.4T patent/DK3377516T3/da active
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2021
- 2021-12-08 JP JP2021198966A patent/JP2022033926A/ja active Pending
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2022
- 2022-05-03 AU AU2022202973A patent/AU2022202973A1/en active Pending
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2023
- 2023-12-27 JP JP2023220529A patent/JP2024041809A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
MD3377516T2 (ro) | 2022-10-31 |
CA3005896A1 (fr) | 2017-05-26 |
US20180339030A1 (en) | 2018-11-29 |
JP2024041809A (ja) | 2024-03-27 |
CN116327902A (zh) | 2023-06-27 |
WO2017087857A1 (fr) | 2017-05-26 |
CN108431022A (zh) | 2018-08-21 |
DK3377516T3 (da) | 2022-09-19 |
LT3377516T (lt) | 2022-09-26 |
EP3377516B1 (fr) | 2022-06-15 |
SI3377516T1 (sl) | 2023-01-31 |
RS63561B1 (sr) | 2022-10-31 |
ES2926386T3 (es) | 2022-10-25 |
JP2022033926A (ja) | 2022-03-02 |
HRP20220994T1 (hr) | 2022-11-11 |
CN115920017A (zh) | 2023-04-07 |
HUE059694T2 (hu) | 2022-12-28 |
PT3377516T (pt) | 2022-09-23 |
EP3377516A4 (fr) | 2019-06-26 |
EP3377516A1 (fr) | 2018-09-26 |
JP2018538265A (ja) | 2018-12-27 |
PL3377516T3 (pl) | 2022-10-10 |
MA43283A (fr) | 2018-09-26 |
EP4130026A1 (fr) | 2023-02-08 |
AU2016356708B2 (en) | 2022-02-03 |
CN116327903A (zh) | 2023-06-27 |
AU2022202973A1 (en) | 2022-05-26 |
KR20180094922A (ko) | 2018-08-24 |
US11033613B2 (en) | 2021-06-15 |
JP6991969B2 (ja) | 2022-03-03 |
CN108431022B (zh) | 2022-08-09 |
AU2016356708A1 (en) | 2018-07-05 |
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