ATE429442T1 - Zusammensetzungen und verfahren zur wt1- spezifischen immuntherapie - Google Patents
Zusammensetzungen und verfahren zur wt1- spezifischen immuntherapieInfo
- Publication number
- ATE429442T1 ATE429442T1 AT02797061T AT02797061T ATE429442T1 AT E429442 T1 ATE429442 T1 AT E429442T1 AT 02797061 T AT02797061 T AT 02797061T AT 02797061 T AT02797061 T AT 02797061T AT E429442 T1 ATE429442 T1 AT E429442T1
- Authority
- AT
- Austria
- Prior art keywords
- compositions
- polypeptide
- methods
- specific immunotherapy
- presenting
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 238000009169 immunotherapy Methods 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 210000000612 antigen-presenting cell Anatomy 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
- 230000003211 malignant effect Effects 0.000 abstract 1
- 206010061289 metastatic neoplasm Diseases 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/002,603 US7901693B2 (en) | 1998-09-30 | 2001-10-30 | Compositions and methods for WT1 specific immunotherapy |
| US10/125,635 US20030039635A1 (en) | 1998-09-30 | 2002-04-16 | Compositions and methods for WT1 specific immunotherapy |
| US10/195,835 US7655249B2 (en) | 1998-09-30 | 2002-07-12 | Compositions and methods for WT1 specific immunotherapy |
| US10/244,830 US20030235557A1 (en) | 1998-09-30 | 2002-09-16 | Compositions and methods for WT1 specific immunotherapy |
| PCT/US2002/035194 WO2003037060A2 (en) | 2001-10-30 | 2002-10-30 | Compositions and methods for wt1 specific immunotherapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE429442T1 true ATE429442T1 (de) | 2009-05-15 |
Family
ID=27485189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02797061T ATE429442T1 (de) | 2001-10-30 | 2002-10-30 | Zusammensetzungen und verfahren zur wt1- spezifischen immuntherapie |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20030235557A1 (de) |
| EP (2) | EP2172476A3 (de) |
| JP (1) | JP4391232B2 (de) |
| KR (1) | KR100970854B1 (de) |
| CN (1) | CN100471868C (de) |
| AT (1) | ATE429442T1 (de) |
| AU (1) | AU2002361584B2 (de) |
| CA (1) | CA2465303C (de) |
| CY (1) | CY1111002T1 (de) |
| DE (1) | DE60232102D1 (de) |
| DK (1) | DK1468014T3 (de) |
| ES (1) | ES2326311T3 (de) |
| NZ (2) | NZ560858A (de) |
| WO (1) | WO2003037060A2 (de) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1038929B (zh) * | 1998-07-31 | 2005-05-06 | 株式会社国际癌症免疫研究所 | 基於癌抑制基因wt1的产物的癌抗原 |
| US7655249B2 (en) | 1998-09-30 | 2010-02-02 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| US7901693B2 (en) | 1998-09-30 | 2011-03-08 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| US7329410B1 (en) | 1998-09-30 | 2008-02-12 | Corixa Corporation | Compositions and method for WT1 specific immunotherapy |
| EP1371664B1 (de) * | 2001-03-22 | 2008-01-09 | International Institute of Cancer Immunology, Inc. | Wti-modifiziertes peptid |
| US7553494B2 (en) | 2001-08-24 | 2009-06-30 | Corixa Corporation | WT1 fusion proteins |
| CA2530184C (en) * | 2003-06-27 | 2015-10-06 | Haruo Sugiyama | Method of selecting patients suitable for wt1 vaccine |
| AU2004273034A1 (en) * | 2003-09-05 | 2005-03-24 | Sanofi Pasteur Limited | Multi-antigen vectors for melanoma |
| US20080070835A1 (en) | 2003-11-05 | 2008-03-20 | International Institute Of Cancer Immunology, Inc | Hla-Dr-Binding Antigen Peptide Derived From Wt1 |
| EP2478913A1 (de) * | 2003-12-01 | 2012-07-25 | Sloan-Kettering Institute For Cancer Research | Synthetische HLA-bindende Peptidanaloga und Verwendungen dafür |
| WO2005087260A1 (en) * | 2004-03-04 | 2005-09-22 | Corixa Corporation | Co-encapsulated wt1 polypeptide and immunostimulant microsphere formulations and methods thereof |
| JP4886507B2 (ja) * | 2004-03-31 | 2012-02-29 | 株式会社癌免疫研究所 | Wt1由来の癌抗原ペプチド |
| EP1657250A1 (de) * | 2004-11-11 | 2006-05-17 | Charité - Universitätsmedizin Berlin | HLA-A*01 bindendes T-Zell-Epitop von WT1 |
| CA2626238C (en) * | 2005-10-17 | 2015-10-06 | Memorial Sloan Kettering Cancer Center | Wt1 hla class ii-binding peptides and compositions and methods comprising same |
| CN102250211A (zh) * | 2006-02-22 | 2011-11-23 | 株式会社癌免疫研究所 | Hla-a*3303限制性wt1肽和包含此肽的药物组合物 |
| US9265816B2 (en) | 2006-04-10 | 2016-02-23 | Sloan Kettering Institute For Cancer Research | Immunogenic WT-1 peptides and methods of use thereof |
| CN100460013C (zh) * | 2006-09-05 | 2009-02-11 | 重庆康卫生物科技有限公司 | 口服重组幽门螺杆菌疫苗及其制备方法 |
| CA2886621A1 (en) * | 2006-12-28 | 2008-07-10 | International Institute Of Cancer Immunology, Inc. | Hla-a*1101-restricted wt1 peptide and pharmaceutical composition comprising the same |
| AU2012227350C1 (en) * | 2006-12-28 | 2015-11-12 | International Institute Of Cancer Immunology, Inc. | HLA-A*1101-Restricted WT1 peptide and pharmaceutical composition comprising the same |
| PL2119778T3 (pl) * | 2007-02-27 | 2016-04-29 | Int Inst Cancer Immunology Inc | Sposób aktywacji pomocniczej komórki T oraz kompozycja do zastosowania w tym sposobie |
| US10093977B2 (en) | 2007-03-05 | 2018-10-09 | International Institute Of Cancer Immunology, Inc. | Cancer antigen-specific T-cell receptor gene, peptide encoded by the gene, and use of them |
| KR101238795B1 (ko) * | 2007-05-24 | 2013-03-07 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 동결건조 항원 조성물 |
| MX2010002002A (es) * | 2007-08-20 | 2010-03-11 | Oncotherapy Science Inc | Peptido foxm1 y agente medicinal que lo contiene. |
| WO2009066462A1 (ja) * | 2007-11-20 | 2009-05-28 | Nec Corporation | 細胞傷害性t細胞の誘導方法、細胞傷害性t細胞の誘導剤、およびそれを用いた医薬組成物およびワクチン |
| TWI469791B (zh) | 2009-02-18 | 2015-01-21 | Oncotherapy Science Inc | Foxm1胜肽以及含此胜肽之疫苗 |
| AR076349A1 (es) * | 2009-04-23 | 2011-06-01 | Int Inst Cancer Immunology Inc | Peptido auxiliar del antigeno del cancer |
| EP2483417B1 (de) * | 2009-09-29 | 2017-03-29 | The Trustees Of The University Of Pennsylvania | Verfahren zur diagnose und/oder behandlung von enzephalitis oder epilepsie |
| NZ609460A (en) | 2010-10-05 | 2015-07-31 | Otsuka Pharma Co Ltd | Method for activating helper t cell |
| CN102161998B (zh) * | 2011-01-14 | 2013-01-09 | 中国人民解放军军事医学科学院附属医院 | 基于b7-1-pe40kdel外毒素融合基因的dna疫苗及其用途 |
| US9675561B2 (en) | 2011-04-28 | 2017-06-13 | President And Fellows Of Harvard College | Injectable cryogel vaccine devices and methods of use thereof |
| KR20140039318A (ko) | 2011-06-28 | 2014-04-01 | 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 | 펩티드 암 항원 특이적 t 세포의 리셉터 유전자 |
| US9851356B2 (en) | 2011-09-14 | 2017-12-26 | International Institute Of Cancer Immunology, Inc. | Method for measuring anti-WT1 antibody |
| CA2861206C (en) | 2012-01-13 | 2021-07-06 | Richard J. O'reilly | Immunogenic wt-1 peptides and methods of use thereof |
| PL2931304T3 (pl) * | 2012-12-13 | 2021-11-08 | The Trustees Of The University Of Pennsylvania | Szczepionka wt1 |
| EA201591168A1 (ru) | 2012-12-17 | 2016-05-31 | Оцука Фармасьютикал Ко., Лтд. | Способ активации хелперной t-клетки |
| US10815273B2 (en) | 2013-01-15 | 2020-10-27 | Memorial Sloan Kettering Cancer Center | Immunogenic WT-1 peptides and methods of use thereof |
| CN110078813B (zh) * | 2013-01-15 | 2023-03-28 | 纪念斯隆凯特林癌症中心 | 免疫原性wt-1肽和其使用方法 |
| KR102045029B1 (ko) * | 2013-02-05 | 2019-11-14 | 닛토덴코 가부시키가이샤 | 점막 투여용 wt1 펩티드 암 백신 조성물 |
| WO2014144885A2 (en) * | 2013-03-15 | 2014-09-18 | The Trustees Of The University Of Pennsylvania | Cancer vaccines and methods of treatment using the same |
| CA2912514A1 (en) * | 2013-05-13 | 2014-11-20 | International Institute Of Cancer Immunology, Inc. | Method for predicting clinical effect of immunotherapy |
| CN110511960B (zh) | 2013-07-15 | 2023-05-23 | 美国卫生和人力服务部 | 抗人乳头瘤病毒16 e6 t细胞受体 |
| US10253075B2 (en) | 2014-02-26 | 2019-04-09 | tella, Inc. | WT1 antigenic polypeptide, and anti-tumor agent containing said polypeptide |
| EP3137105A4 (de) | 2014-04-30 | 2017-12-27 | President and Fellows of Harvard College | Kombinationsimpfstoffvorrichtungen und -verfahren zur abtötung von krebszellen |
| SMT202200370T1 (it) | 2015-11-20 | 2022-11-18 | Memorial Sloan Kettering Cancer Center | Composizione per il trattamento del cancro |
| CN105254760B (zh) * | 2015-11-21 | 2018-08-17 | 福州迈新生物技术开发有限公司 | 一株分泌抗wt1蛋白的单克隆抗体及其应用 |
| CN115487351A (zh) | 2016-02-06 | 2022-12-20 | 哈佛学院校长同事会 | 重塑造血巢以重建免疫 |
| EP3484448B1 (de) | 2016-07-13 | 2025-04-09 | President and Fellows of Harvard College | Antigenpräsentierende zellmimetische gerüste und verfahren zur herstellung und verwendung davon |
| RU2770060C2 (ru) | 2016-08-02 | 2022-04-14 | Президент Энд Феллоуз Оф Гарвард Колледж | Биологические материалы для модуляции иммунных ответов |
| MX2019003176A (es) * | 2016-09-23 | 2019-07-04 | Hutchinson Fred Cancer Res | Receptores de linfocitos t (tcr) especificos del antigeno menor de histocompatibilidad (h) ah-1 y sus usos. |
| US12383608B2 (en) | 2016-11-30 | 2025-08-12 | Sumitomo Pharma Co., Ltd. | WT1 helper peptides and combinations of WT1 helper peptide and conjugate of cancer antigen peptides |
| EP3604325A4 (de) | 2017-03-30 | 2021-01-13 | Sumitomo Dainippon Pharma Co., Ltd. | Wt1-krebs-antigen-peptid und peptid-konjugat-körper damit |
| WO2018227205A1 (en) * | 2017-06-09 | 2018-12-13 | President And Fellows Of Harvard College | Compositions for inducing an immune response |
| WO2020061129A1 (en) | 2018-09-19 | 2020-03-26 | President And Fellows Of Harvard College | Compositions and methods for labeling and modulation of cells in vitro and in vivo |
| KR20210068060A (ko) | 2018-09-28 | 2021-06-08 | 다이니뽄 스미토모 세이야쿠 가부시키가이샤 | 주사용 조성물 |
| EP4034148A4 (de) | 2019-09-23 | 2025-09-10 | Harvard College | Biomaterialbasierter antigenfreier impfstoff und verwendung davon |
| MX2022014249A (es) | 2020-05-12 | 2023-02-22 | Sumitomo Pharma Co Ltd | Composición farmacéutica para tratar el cáncer. |
| CN118076382A (zh) * | 2021-08-12 | 2024-05-24 | 株式会社癌免疫研究所 | 用于治疗或预防癌症的药用组合物和方法 |
| CN113730562B (zh) * | 2021-09-10 | 2024-06-04 | 中国人民解放军陆军军医大学 | 以壳聚糖修饰plga的wt1多肽纳米粒疫苗及其制备方法和应用 |
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2002
- 2002-09-16 US US10/244,830 patent/US20030235557A1/en not_active Abandoned
- 2002-10-30 NZ NZ560858A patent/NZ560858A/en not_active IP Right Cessation
- 2002-10-30 NZ NZ533220A patent/NZ533220A/en not_active IP Right Cessation
- 2002-10-30 EP EP09153790A patent/EP2172476A3/de not_active Withdrawn
- 2002-10-30 KR KR1020047006659A patent/KR100970854B1/ko not_active Expired - Fee Related
- 2002-10-30 ES ES02797061T patent/ES2326311T3/es not_active Expired - Lifetime
- 2002-10-30 EP EP02797061A patent/EP1468014B1/de not_active Expired - Lifetime
- 2002-10-30 WO PCT/US2002/035194 patent/WO2003037060A2/en not_active Ceased
- 2002-10-30 AU AU2002361584A patent/AU2002361584B2/en not_active Ceased
- 2002-10-30 DE DE60232102T patent/DE60232102D1/de not_active Expired - Lifetime
- 2002-10-30 CA CA2465303A patent/CA2465303C/en not_active Expired - Fee Related
- 2002-10-30 JP JP2003539419A patent/JP4391232B2/ja not_active Expired - Fee Related
- 2002-10-30 AT AT02797061T patent/ATE429442T1/de active
- 2002-10-30 DK DK02797061T patent/DK1468014T3/da active
- 2002-10-30 CN CNB028264924A patent/CN100471868C/zh not_active Expired - Fee Related
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2009
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Also Published As
| Publication number | Publication date |
|---|---|
| DE60232102D1 (de) | 2009-06-04 |
| WO2003037060A3 (en) | 2004-08-12 |
| AU2002361584B2 (en) | 2009-07-23 |
| NZ533220A (en) | 2008-04-30 |
| US20030235557A1 (en) | 2003-12-25 |
| KR20050042226A (ko) | 2005-05-06 |
| DK1468014T3 (da) | 2009-08-10 |
| CN1671733A (zh) | 2005-09-21 |
| EP2172476A3 (de) | 2010-06-23 |
| CN100471868C (zh) | 2009-03-25 |
| EP1468014A4 (de) | 2006-05-17 |
| EP1468014B1 (de) | 2009-04-22 |
| WO2003037060A2 (en) | 2003-05-08 |
| CA2465303A1 (en) | 2003-05-08 |
| JP2005518192A (ja) | 2005-06-23 |
| ES2326311T3 (es) | 2009-10-07 |
| NZ560858A (en) | 2009-06-26 |
| KR100970854B1 (ko) | 2010-07-20 |
| CY1111002T1 (el) | 2015-06-11 |
| JP4391232B2 (ja) | 2009-12-24 |
| EP1468014A2 (de) | 2004-10-20 |
| EP2172476A2 (de) | 2010-04-07 |
| CA2465303C (en) | 2011-09-13 |
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