DE60305520D1 - 2" oxo-voruscharin und derivaten - Google Patents

2" oxo-voruscharin und derivaten

Info

Publication number
DE60305520D1
DE60305520D1 DE60305520T DE60305520T DE60305520D1 DE 60305520 D1 DE60305520 D1 DE 60305520D1 DE 60305520 T DE60305520 T DE 60305520T DE 60305520 T DE60305520 T DE 60305520T DE 60305520 D1 DE60305520 D1 DE 60305520D1
Authority
DE
Germany
Prior art keywords
oxo
derivatives
disclosed
voruscharine
voruscharin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60305520T
Other languages
English (en)
Other versions
DE60305520T2 (de
Inventor
Quaquebeke Eric Van
Jean-Claude Braekman
Gentiane Simon
Pierre Guissou
Germaine Nacoulma
Janique Dewelle
Francis Darro
Robert Kiss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Unibioscreen SA
Universite Libre de Bruxelles ULB
Original Assignee
Unibioscreen SA
Universite Libre de Bruxelles ULB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP20020447192 external-priority patent/EP1408043A1/de
Application filed by Unibioscreen SA, Universite Libre de Bruxelles ULB filed Critical Unibioscreen SA
Application granted granted Critical
Publication of DE60305520D1 publication Critical patent/DE60305520D1/de
Publication of DE60305520T2 publication Critical patent/DE60305520T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrrole Compounds (AREA)
  • Steroid Compounds (AREA)
DE60305520T 2002-10-09 2003-10-09 2" oxo-voruscharin und derivaten Expired - Lifetime DE60305520T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP20020447192 EP1408043A1 (de) 2002-10-09 2002-10-09 2" Oxo-Voruscharin und Analoge davon
EP02447192 2002-10-09
US42006702P 2002-10-21 2002-10-21
US420067P 2002-10-21
PCT/EP2003/011194 WO2004033465A1 (en) 2002-10-09 2003-10-09 2' oxo-voruscharin and derivatives thereof

Publications (2)

Publication Number Publication Date
DE60305520D1 true DE60305520D1 (de) 2006-06-29
DE60305520T2 DE60305520T2 (de) 2007-05-16

Family

ID=32095057

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60305520T Expired - Lifetime DE60305520T2 (de) 2002-10-09 2003-10-09 2" oxo-voruscharin und derivaten

Country Status (13)

Country Link
US (1) US7320971B2 (de)
EP (1) EP1551850B1 (de)
JP (1) JP2006511483A (de)
AT (1) ATE327240T1 (de)
AU (1) AU2003273974B2 (de)
CA (1) CA2501774C (de)
DE (1) DE60305520T2 (de)
DK (1) DK1551850T3 (de)
ES (1) ES2265583T3 (de)
HK (1) HK1082727A1 (de)
MX (1) MXPA05003633A (de)
PT (1) PT1551850E (de)
WO (1) WO2004033465A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2009004890A (es) * 2006-11-09 2009-05-21 Unibioscreen Sa Direccionamiento de subunidades alpha-1 o alpha-3 de na+, k+-atpasa en el tratamiento de enfermedades proliferativas.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5645988A (en) 1991-05-08 1997-07-08 The United States Of America As Represented By The Department Of Health And Human Services Methods of identifying drugs with selective effects against cancer cells
GB9710698D0 (en) * 1997-05-24 1997-07-16 Verkaik Margaretha S E Composition

Also Published As

Publication number Publication date
DE60305520T2 (de) 2007-05-16
ES2265583T3 (es) 2007-02-16
MXPA05003633A (es) 2005-12-14
WO2004033465B1 (en) 2004-06-17
HK1082727A1 (en) 2006-06-16
PT1551850E (pt) 2006-10-31
DK1551850T3 (da) 2006-09-25
WO2004033465A1 (en) 2004-04-22
CA2501774C (en) 2011-12-06
ATE327240T1 (de) 2006-06-15
US7320971B2 (en) 2008-01-22
US20060166952A1 (en) 2006-07-27
EP1551850A1 (de) 2005-07-13
EP1551850B1 (de) 2006-05-24
AU2003273974A1 (en) 2004-05-04
CA2501774A1 (en) 2004-04-22
AU2003273974B2 (en) 2009-08-13
JP2006511483A (ja) 2006-04-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition