DK1465921T3 - Agonister til corticotropinfrigörelsesfaktor receptor-2 - Google Patents

Agonister til corticotropinfrigörelsesfaktor receptor-2

Info

Publication number
DK1465921T3
DK1465921T3 DK03703867T DK03703867T DK1465921T3 DK 1465921 T3 DK1465921 T3 DK 1465921T3 DK 03703867 T DK03703867 T DK 03703867T DK 03703867 T DK03703867 T DK 03703867T DK 1465921 T3 DK1465921 T3 DK 1465921T3
Authority
DK
Denmark
Prior art keywords
agonists
factor receptor
release factor
corticotropin release
corticotropin
Prior art date
Application number
DK03703867T
Other languages
Danish (da)
English (en)
Inventor
Robert Joseph Isfort
Wieslaw Adam Mazur
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Application granted granted Critical
Publication of DK1465921T3 publication Critical patent/DK1465921T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57509—Corticotropin releasing factor [CRF] (Urotensin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK03703867T 2002-01-16 2003-01-16 Agonister til corticotropinfrigörelsesfaktor receptor-2 DK1465921T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US34911702P 2002-01-16 2002-01-16
US37633702P 2002-04-29 2002-04-29
US38889502P 2002-06-14 2002-06-14
US41198802P 2002-09-19 2002-09-19

Publications (1)

Publication Number Publication Date
DK1465921T3 true DK1465921T3 (da) 2006-11-27

Family

ID=27617822

Family Applications (2)

Application Number Title Priority Date Filing Date
DK03703867T DK1465921T3 (da) 2002-01-16 2003-01-16 Agonister til corticotropinfrigörelsesfaktor receptor-2
DK03731965T DK1465923T3 (da) 2002-01-16 2003-01-16 Corticotroprinafgivende faktor 2-receptoragonister

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK03731965T DK1465923T3 (da) 2002-01-16 2003-01-16 Corticotroprinafgivende faktor 2-receptoragonister

Country Status (30)

Country Link
US (7) US6936585B2 (fr)
EP (4) EP1465921B1 (fr)
JP (3) JP4508649B2 (fr)
KR (3) KR100758858B1 (fr)
CN (3) CN100475844C (fr)
AR (3) AR038142A1 (fr)
AT (4) ATE362488T1 (fr)
AU (2) AU2003237419B2 (fr)
BR (3) BR0306878A (fr)
CA (3) CA2470656C (fr)
CY (1) CY1106133T1 (fr)
DE (4) DE60318547T2 (fr)
DK (2) DK1465921T3 (fr)
ES (4) ES2309909T3 (fr)
HK (1) HK1078095A1 (fr)
IL (5) IL162529A0 (fr)
MA (3) MA27592A1 (fr)
MX (3) MXPA04006883A (fr)
MY (1) MY140306A (fr)
NO (3) NO20043371L (fr)
NZ (3) NZ533600A (fr)
PE (3) PE20030747A1 (fr)
PL (3) PL373529A1 (fr)
PT (2) PT1465921E (fr)
RU (1) RU2294333C2 (fr)
SA (3) SA03230565B1 (fr)
SI (1) SI1465921T1 (fr)
TW (3) TW200302278A (fr)
WO (3) WO2003062277A1 (fr)
ZA (1) ZA200404995B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001289916A1 (en) * 2000-09-22 2002-04-02 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften Methods for improving the antagonistic/agonistic properties of peptidic antagonists/agonists of the corticotropin-releasing factor receptor (crfr)
US6936585B2 (en) * 2002-01-16 2005-08-30 The Procter & Gamble Company Corticotropin releasing factor 2 receptor agonists
WO2005103690A2 (fr) * 2004-04-24 2005-11-03 Bayer Healthcare Ag Diagnostic et therapeutique de maladies associees au recepteur de l'hormone de liberation de la corticotropine 2 (crhr2)
EP1871888A4 (fr) * 2005-03-30 2013-08-21 Novartis Vaccines & Diagnostic Haemophilus influenzae de type b
US7815905B2 (en) 2006-01-27 2010-10-19 Research Development Foundation Methods of increasing insulin sensitivity or decreasing insulin secretion by administering corticotropin releasing factor receptor-2 inhibitors
WO2009043469A2 (fr) * 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag Utilisation d'un peptide en tant qu'agent thérapeutique
WO2009039994A1 (fr) * 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Utilisation d'un peptide en tant qu'agent thérapeutique
WO2009046874A1 (fr) * 2007-09-11 2009-04-16 Mondobiotech Laboratories Ag Polythérapie de peptide potentialisateur de la trh et de stresscopine
CA2742710A1 (fr) 2008-11-04 2010-05-14 Janssen Pharmaceutica Nv Agonistes peptidiques du recepteur d'hormone de liberation de la corticotropine de type 2 (crhr2) et leurs utilisations
EP2206726A1 (fr) * 2009-01-08 2010-07-14 Universite Joseph Fourier Outils non invasifs pour la détection de plaques athérosclérotique vulnérables
EP2496248A2 (fr) * 2009-11-04 2012-09-12 Janssen Pharmaceutica, N.V. Méthode de traitement de l'insuffisance cardiaque avec des peptides de type stresscopine
WO2013063046A1 (fr) 2011-10-24 2013-05-02 Research Development Foundation Procédés d'augmentation de la sécrétion d'insuline par costimulation des récepteurs du facteur de libération de la corticotropine
EP3311830A1 (fr) 2012-02-14 2018-04-25 The Regents of The University of California Administration systémique et expression régulée des gènes à action paracrine pour les maladies cardiovasculaires et autres états
JOP20170153A1 (ar) * 2016-07-15 2019-01-30 Lilly Co Eli نظائر urocortin-2 جديدة معدلة بحمض دهني لعلاج داء السكري وأمراض الكلى المزمنة
JP2019533021A (ja) * 2016-10-20 2019-11-14 コーティーン インコーポレイテッド 不適応のストレス応答に寄与する疾患を処置する方法
CN110755434B (zh) * 2018-07-27 2022-03-15 中国医学科学院药物研究所 化合物palosuran防治骨骼肌萎缩等疾病的用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5235036A (en) * 1991-05-31 1993-08-10 The Salk Institute For Biological Studies Crf analogs
EP0860501A3 (fr) 1994-06-14 1999-05-19 Neurocrine Biosciences, Inc. Récepteurs du facteur 2 libérant la corticotropine
US5786203A (en) 1994-06-14 1998-07-28 Neurocrine Biosciences, Inc. Isolated nucleic acid encoding corticotropin-releasing factor2 receptors
US5824771A (en) 1994-12-12 1998-10-20 The Salk Institute For Biological Studies Cyclic CRF agonists
US5663292A (en) 1994-12-12 1997-09-02 The Salk Institute For Biological Studies Cyclic CRF analogs
US5660824A (en) 1995-05-24 1997-08-26 Grabstein; Kenneth H. Muscle trophic factor
EP0845035A2 (fr) 1995-06-13 1998-06-03 The Salk Institute For Biological Studies Peptides d'urocortine
US5869450A (en) 1996-03-06 1999-02-09 The Regents Of The University Of California Anti-inflammatory compositions and method with corticotropin-releasing factor analogs
IL154102A0 (en) 2000-08-04 2003-07-31 Res Dev Foundation Urocortin proteins and uses thereof
US20020082409A1 (en) 2000-10-26 2002-06-27 Hsu Sheau Yu Stresscopins and their uses
US6670140B2 (en) * 2001-03-06 2003-12-30 The Procter & Gamble Company Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors
US6936585B2 (en) 2002-01-16 2005-08-30 The Procter & Gamble Company Corticotropin releasing factor 2 receptor agonists

Also Published As

Publication number Publication date
US7462597B2 (en) 2008-12-09
DE60307044D1 (de) 2006-09-07
EP1465923B1 (fr) 2007-05-16
BR0306838A (pt) 2005-04-05
IL162529A0 (en) 2005-11-20
ATE334147T1 (de) 2006-08-15
CN100475844C (zh) 2009-04-08
US20060025339A1 (en) 2006-02-02
US20080004435A1 (en) 2008-01-03
SA03230565B1 (ar) 2006-10-31
PE20030849A1 (es) 2003-12-01
IL197774A0 (en) 2009-12-24
DE60318547T2 (de) 2008-12-24
RU2294333C2 (ru) 2007-02-27
AR038142A1 (es) 2004-12-29
BR0306878A (pt) 2004-10-26
US7192923B2 (en) 2007-03-20
US20090124793A1 (en) 2009-05-14
US20030148958A1 (en) 2003-08-07
EP1465921A2 (fr) 2004-10-13
ATE383372T1 (de) 2008-01-15
KR100735586B1 (ko) 2007-07-04
ATE362488T1 (de) 2007-06-15
US20030148956A1 (en) 2003-08-07
CN100391972C (zh) 2008-06-04
CN1617887A (zh) 2005-05-18
TW200302278A (en) 2003-08-01
KR20040082392A (ko) 2004-09-24
EP1465921B1 (fr) 2006-07-26
NZ533600A (en) 2007-02-23
JP4489434B2 (ja) 2010-06-23
TW200302276A (en) 2003-08-01
WO2003062269A3 (fr) 2003-11-06
CA2470656A1 (fr) 2003-07-31
US7632933B2 (en) 2009-12-15
JP2005521387A (ja) 2005-07-21
AU2003205197B2 (en) 2006-03-02
US20030148957A1 (en) 2003-08-07
MXPA04006884A (es) 2004-12-06
IL162530A0 (en) 2005-11-20
US7192924B2 (en) 2007-03-20
NZ533599A (en) 2007-03-30
ATE398632T1 (de) 2008-07-15
TW200302277A (en) 2003-08-01
DE60307044T2 (de) 2007-02-15
PL371364A1 (en) 2005-06-13
NO20043366L (no) 2004-10-06
BR0306826A (pt) 2005-09-06
MA27591A1 (fr) 2005-11-01
TWI300442B (en) 2008-09-01
ZA200404995B (en) 2005-06-29
CN1617886A (zh) 2005-05-18
US7897731B2 (en) 2011-03-01
CY1106133T1 (el) 2011-06-08
PT1465923E (pt) 2007-08-06
CN1617885A (zh) 2005-05-18
SA03230564B1 (ar) 2006-10-31
SI1465921T1 (sl) 2006-10-31
MA27592A1 (fr) 2005-11-01
RU2004124847A (ru) 2005-04-20
CA2470656C (fr) 2011-06-28
CA2470731C (fr) 2011-06-21
ES2269976T3 (es) 2007-04-01
AR038144A1 (es) 2004-12-29
KR20040082390A (ko) 2004-09-24
MA27590A1 (fr) 2005-11-01
PT1465921E (pt) 2006-12-29
KR20040082389A (ko) 2004-09-24
DE60321730D1 (de) 2008-07-31
WO2003062277A1 (fr) 2003-07-31
ES2299701T3 (es) 2008-06-01
JP4508648B2 (ja) 2010-07-21
DE60313845D1 (de) 2007-06-28
NZ533598A (en) 2007-03-30
KR100758857B1 (ko) 2007-09-14
IL196384A0 (en) 2011-07-31
JP4508649B2 (ja) 2010-07-21
CA2470731A1 (fr) 2003-07-31
CA2470743C (fr) 2011-12-13
AR038143A1 (es) 2004-12-29
EP1724283A2 (fr) 2006-11-22
US6936585B2 (en) 2005-08-30
EP1724283B1 (fr) 2008-06-18
US7608701B2 (en) 2009-10-27
MXPA04006883A (es) 2004-12-06
DE60313845T2 (de) 2008-01-31
SA03230564A (ar) 2005-12-03
MXPA04006885A (es) 2004-12-06
DK1465923T3 (da) 2007-07-02
PL373139A1 (en) 2005-08-22
PL373529A1 (en) 2005-09-05
DE60318547D1 (de) 2008-02-21
ES2309909T3 (es) 2008-12-16
EP1465923A1 (fr) 2004-10-13
KR100758858B1 (ko) 2007-09-14
CA2470743A1 (fr) 2003-07-31
ES2287484T3 (es) 2007-12-16
HK1078095A1 (en) 2006-03-03
MY140306A (en) 2009-12-31
EP1724283A3 (fr) 2007-04-11
PE20030747A1 (es) 2003-10-23
SA03230565A (ar) 2005-12-03
WO2003062268A3 (fr) 2003-11-27
PE20030974A1 (es) 2003-12-26
NO20043371L (no) 2004-10-06
IL162431A0 (en) 2005-11-20
JP2005525101A (ja) 2005-08-25
JP2005522191A (ja) 2005-07-28
WO2003062268A2 (fr) 2003-07-31
NO20043396L (no) 2004-10-06
AU2003237419B2 (en) 2006-04-13
EP1465922B1 (fr) 2008-01-09
US20100197579A1 (en) 2010-08-05
WO2003062269A2 (fr) 2003-07-31
EP1465922A2 (fr) 2004-10-13

Similar Documents

Publication Publication Date Title
NO20055742D0 (no) Gjenget forbindelse for stalror
DK1469743T3 (da) Fremgangsmåder til stabilisering af hygroskopiske bestanddele til drøvtyggere
IS7525A (is) Skjalaformgerðar kennimerki
DK1465921T3 (da) Agonister til corticotropinfrigörelsesfaktor receptor-2
DE60308850D1 (de) Pyridinoylpiperidine als 5-ht1f agonisten
DE602005023460D1 (de) Antimykotische polypeptide
DK1540907T3 (da) Konferencesystem
MA28545B1 (fr) Amides tri (cyclo) substitués
DE502004005652D1 (de) Kontrolliertes freisetzungssystem enthaltend saccharoseacetatisobutyrat
ITTO20050184A1 (it) Connettore rapido
DE602004011999D1 (de) Mehrbenutzer-übertragungssystem
DE602005026950D1 (de) Tomographiesystem
DE502005008468D1 (de) Bildaufnahmesystem
IS7582A (is) Hraðlosandi lyfjablanda
DE60324018D1 (de) Agonisten
ITMO20040105A1 (it) Apparato di lancio
DE502005002052D1 (de) Transportvorrichtung
DE502005005082D1 (de) Bildaufnahmesystem
DE10224030B4 (de) Spannsystem
DE602004031792D1 (de) Bilderzeugungssystem
ATE491683T1 (de) Muskarine agonisten
ES1052410Y (es) Dispositivo para sujecion de pequeñas piezas metalicas.
FI6455U1 (fi) Virtuaali-ikkunajärjestelmä
DE602006000260D1 (de) Kamerasystem
DE102005045405B8 (de) Kamerasystem