CY1106133T1 - Αγωνιστες υποδοχεα 2 παραγοντα απελευθερωσης κορτικοτροπινης - Google Patents

Αγωνιστες υποδοχεα 2 παραγοντα απελευθερωσης κορτικοτροπινης

Info

Publication number
CY1106133T1
CY1106133T1 CY20061101051T CY061101051T CY1106133T1 CY 1106133 T1 CY1106133 T1 CY 1106133T1 CY 20061101051 T CY20061101051 T CY 20061101051T CY 061101051 T CY061101051 T CY 061101051T CY 1106133 T1 CY1106133 T1 CY 1106133T1
Authority
CY
Cyprus
Prior art keywords
corticotropin
releasing factor
agonists
effective
treatment
Prior art date
Application number
CY20061101051T
Other languages
English (en)
Inventor
Robert Joseph Isfort
Wieslaw Adam Mazur
Original Assignee
The Procter & Gamble Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Procter & Gamble Company filed Critical The Procter & Gamble Company
Publication of CY1106133T1 publication Critical patent/CY1106133T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57509—Corticotropin releasing factor [CRF] (Urotensin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Απομονωθέντα παράγωγα παράγοντα απελευθέρωσης κορτικοτροπίνης και νουκλεϊκά οξέα που τα κωδικοποιούν, είναι αποτελεσματικά για τη θεραπεία παθήσεων που διαμορφώνονται από τον υποδοχέα 2 παράγοντα απελευθέρωσης κορτικοτροπίνης όπως η μυϊκή δυστροφία.
CY20061101051T 2002-01-16 2006-07-28 Αγωνιστες υποδοχεα 2 παραγοντα απελευθερωσης κορτικοτροπινης CY1106133T1 (el)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US34911702P 2002-01-16 2002-01-16
US37633702P 2002-04-29 2002-04-29
US38889502P 2002-06-14 2002-06-14
US41198802P 2002-09-19 2002-09-19
PCT/US2003/001461 WO2003062269A2 (en) 2002-01-16 2003-01-16 Corticotropin releasing factor receptor 2 agonists

Publications (1)

Publication Number Publication Date
CY1106133T1 true CY1106133T1 (el) 2011-06-08

Family

ID=27617822

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061101051T CY1106133T1 (el) 2002-01-16 2006-07-28 Αγωνιστες υποδοχεα 2 παραγοντα απελευθερωσης κορτικοτροπινης

Country Status (30)

Country Link
US (7) US7192924B2 (el)
EP (4) EP1465921B1 (el)
JP (3) JP4508649B2 (el)
KR (3) KR100758858B1 (el)
CN (3) CN1617887A (el)
AR (3) AR038142A1 (el)
AT (4) ATE334147T1 (el)
AU (2) AU2003205197B2 (el)
BR (3) BR0306826A (el)
CA (3) CA2470731C (el)
CY (1) CY1106133T1 (el)
DE (4) DE60313845T2 (el)
DK (2) DK1465923T3 (el)
ES (4) ES2269976T3 (el)
HK (1) HK1078095A1 (el)
IL (5) IL162431A0 (el)
MA (3) MA27591A1 (el)
MX (3) MXPA04006885A (el)
MY (1) MY140306A (el)
NO (3) NO20043366L (el)
NZ (3) NZ533598A (el)
PE (3) PE20030974A1 (el)
PL (3) PL373529A1 (el)
PT (2) PT1465921E (el)
RU (1) RU2294333C2 (el)
SA (3) SA03230564B1 (el)
SI (1) SI1465921T1 (el)
TW (3) TWI300442B (el)
WO (3) WO2003062269A2 (el)
ZA (1) ZA200404995B (el)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040049009A1 (en) * 2000-09-22 2004-03-11 Klaus Eckart Methods for improving the antagonistic/agonistic properties of peptidic antagonists/agonists of the corticotropin-releasing factor receptor (crfr)
US7192924B2 (en) * 2002-01-16 2007-03-20 The Procter & Gamble Company Corticotropin releasing factor 2 receptor agonists
WO2005103690A2 (en) * 2004-04-24 2005-11-03 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with corticotropin releasing hormone receptor 2 (crhr2)
US20100034822A1 (en) * 2005-03-30 2010-02-11 Vega Masignani Haemophilus Influenzae Type B
US7815905B2 (en) 2006-01-27 2010-10-19 Research Development Foundation Methods of increasing insulin sensitivity or decreasing insulin secretion by administering corticotropin releasing factor receptor-2 inhibitors
WO2009046874A1 (en) * 2007-09-11 2009-04-16 Mondobiotech Laboratories Ag Therapeutic combination of trh-potentiating peptide and stresscopin
KR20100056507A (ko) * 2007-09-11 2010-05-27 몬도바이오테크 래보래토리즈 아게 치료제로서의 펩티드 ｐｒｏ－ｇｌｙ－ｔｈｒ－ｃｙｓ－ｇｌｕ－ｉｌｅ－ｃｙｓ－ａｌａ－ｔｙｒ－ａｌａ－ａｌａ－ｃｙｓ－ｔｈｒ－ｇｌｙ－ｃｙｓ의 용도
RU2010114038A (ru) * 2007-09-11 2011-10-20 Мондобайотек Лабораториз Аг (Li) Применение адреномедуллина в качестве терапевтического средства для лечения избыточного ангиогенеза
EA201170647A1 (ru) * 2008-11-04 2011-12-30 Янссен Фармацевтика Нв Пептиды-агонисты crhr2 и их использование
EP2206726A1 (en) * 2009-01-08 2010-07-14 Universite Joseph Fourier Non-invasive tools for detecting vulnerable atherosclerotic plaques
MX2012005262A (es) * 2009-11-04 2012-09-28 Janssen Pharmaceutica Nv Metodo para tratar la insuficiencia cardiaca con petidos tipo estrescopina.
US9314506B2 (en) 2011-10-24 2016-04-19 Research Development Foundation Methods for increasing insulin secretion by co-stimulation of corticotropin-releasing factor receptors
AU2013221615B2 (en) * 2012-02-14 2018-02-22 The Regents Of The University Of California Systemic delivery and regulated expression of paracrine genes for cardiovascular diseases and other conditions
JOP20170153A1 (ar) 2016-07-15 2019-01-30 Lilly Co Eli نظائر urocortin-2 جديدة معدلة بحمض دهني لعلاج داء السكري وأمراض الكلى المزمنة
AU2017345785A1 (en) 2016-10-20 2019-05-16 Cortene Inc. Methods of treating diseases resulting from a maladapted stress response
CN110755434B (zh) * 2018-07-27 2022-03-15 中国医学科学院药物研究所 化合物palosuran防治骨骼肌萎缩等疾病的用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5235036A (en) * 1991-05-31 1993-08-10 The Salk Institute For Biological Studies Crf analogs
EP0860501A3 (en) 1994-06-14 1999-05-19 Neurocrine Biosciences, Inc. Corticotropin-releasing factor2 receptors
US5786203A (en) 1994-06-14 1998-07-28 Neurocrine Biosciences, Inc. Isolated nucleic acid encoding corticotropin-releasing factor2 receptors
US5824771A (en) * 1994-12-12 1998-10-20 The Salk Institute For Biological Studies Cyclic CRF agonists
US5663292A (en) 1994-12-12 1997-09-02 The Salk Institute For Biological Studies Cyclic CRF analogs
US5660824A (en) 1995-05-24 1997-08-26 Grabstein; Kenneth H. Muscle trophic factor
WO1997000063A2 (en) 1995-06-13 1997-01-03 The Salk Institute For Biological Studies Urocortin peptides
US5869450A (en) 1996-03-06 1999-02-09 The Regents Of The University Of California Anti-inflammatory compositions and method with corticotropin-releasing factor analogs
EP1305334B1 (en) 2000-08-04 2008-09-17 Research Development Foundation Urocortin proteins and uses thereof
US20020082409A1 (en) 2000-10-26 2002-06-27 Hsu Sheau Yu Stresscopins and their uses
US6670140B2 (en) * 2001-03-06 2003-12-30 The Procter & Gamble Company Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors
US7192924B2 (en) * 2002-01-16 2007-03-20 The Procter & Gamble Company Corticotropin releasing factor 2 receptor agonists

Also Published As

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PL373529A1 (en) 2005-09-05
US7462597B2 (en) 2008-12-09
BR0306878A (pt) 2004-10-26
CA2470656A1 (en) 2003-07-31
CN100391972C (zh) 2008-06-04
US20060025339A1 (en) 2006-02-02
KR100758857B1 (ko) 2007-09-14
US7608701B2 (en) 2009-10-27
US20030148956A1 (en) 2003-08-07
IL162529A0 (en) 2005-11-20
DE60313845T2 (de) 2008-01-31
ATE362488T1 (de) 2007-06-15
NO20043366L (no) 2004-10-06
AU2003237419B2 (en) 2006-04-13
US20100197579A1 (en) 2010-08-05
DK1465921T3 (da) 2006-11-27
PT1465921E (pt) 2006-12-29
ES2299701T3 (es) 2008-06-01
CN1617886A (zh) 2005-05-18
MA27590A1 (fr) 2005-11-01
DE60307044D1 (de) 2006-09-07
WO2003062269A2 (en) 2003-07-31
EP1724283B1 (en) 2008-06-18
IL196384A0 (en) 2011-07-31
KR20040082392A (ko) 2004-09-24
US7632933B2 (en) 2009-12-15
NZ533598A (en) 2007-03-30
WO2003062268A3 (en) 2003-11-27
SA03230565B1 (ar) 2006-10-31
MY140306A (en) 2009-12-31
EP1724283A3 (en) 2007-04-11
MA27592A1 (fr) 2005-11-01
KR20040082389A (ko) 2004-09-24
PL371364A1 (en) 2005-06-13
JP4508648B2 (ja) 2010-07-21
KR20040082390A (ko) 2004-09-24
CA2470743A1 (en) 2003-07-31
EP1465923B1 (en) 2007-05-16
DE60321730D1 (de) 2008-07-31
JP4489434B2 (ja) 2010-06-23
TW200302276A (en) 2003-08-01
TW200302277A (en) 2003-08-01
CN100475844C (zh) 2009-04-08
NO20043396L (no) 2004-10-06
WO2003062277A1 (en) 2003-07-31
BR0306838A (pt) 2005-04-05
AR038142A1 (es) 2004-12-29
EP1465923A1 (en) 2004-10-13
SA03230564B1 (ar) 2006-10-31
AU2003205197B2 (en) 2006-03-02
PE20030974A1 (es) 2003-12-26
NZ533600A (en) 2007-02-23
ATE398632T1 (de) 2008-07-15
AR038143A1 (es) 2004-12-29
JP2005522191A (ja) 2005-07-28
PL373139A1 (en) 2005-08-22
MXPA04006885A (es) 2004-12-06
JP2005521387A (ja) 2005-07-21
JP2005525101A (ja) 2005-08-25
CA2470731C (en) 2011-06-21
ES2309909T3 (es) 2008-12-16
CN1617887A (zh) 2005-05-18
HK1078095A1 (en) 2006-03-03
PE20030849A1 (es) 2003-12-01
IL162530A0 (en) 2005-11-20
US7897731B2 (en) 2011-03-01
US7192923B2 (en) 2007-03-20
WO2003062268A2 (en) 2003-07-31
BR0306826A (pt) 2005-09-06
WO2003062269A3 (en) 2003-11-06
ZA200404995B (en) 2005-06-29
PT1465923E (pt) 2007-08-06
SI1465921T1 (sl) 2006-10-31
DK1465923T3 (da) 2007-07-02
IL197774A0 (en) 2009-12-24
ATE334147T1 (de) 2006-08-15
TW200302278A (en) 2003-08-01
NZ533599A (en) 2007-03-30
MA27591A1 (fr) 2005-11-01
ES2269976T3 (es) 2007-04-01
EP1465922B1 (en) 2008-01-09
CA2470731A1 (en) 2003-07-31
US20080004435A1 (en) 2008-01-03
IL162431A0 (en) 2005-11-20
US20030148958A1 (en) 2003-08-07
SA03230564A (ar) 2005-12-03
EP1465921A2 (en) 2004-10-13
PE20030747A1 (es) 2003-10-23
US7192924B2 (en) 2007-03-20
RU2294333C2 (ru) 2007-02-27
CA2470743C (en) 2011-12-13
NO20043371L (no) 2004-10-06
ATE383372T1 (de) 2008-01-15
CA2470656C (en) 2011-06-28
MXPA04006883A (es) 2004-12-06
CN1617885A (zh) 2005-05-18
DE60307044T2 (de) 2007-02-15
ES2287484T3 (es) 2007-12-16
MXPA04006884A (es) 2004-12-06
EP1465921B1 (en) 2006-07-26
DE60318547T2 (de) 2008-12-24
SA03230565A (ar) 2005-12-03
KR100735586B1 (ko) 2007-07-04
KR100758858B1 (ko) 2007-09-14
EP1724283A2 (en) 2006-11-22
US6936585B2 (en) 2005-08-30
EP1465922A2 (en) 2004-10-13
DE60318547D1 (de) 2008-02-21
DE60313845D1 (de) 2007-06-28
US20090124793A1 (en) 2009-05-14
AR038144A1 (es) 2004-12-29
JP4508649B2 (ja) 2010-07-21
TWI300442B (en) 2008-09-01
RU2004124847A (ru) 2005-04-20
US20030148957A1 (en) 2003-08-07

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