DK1419151T3 - Krystaller indeholdende et malatsyresalt af N-[2-(diethylamino)ethyl]-5-[(5-fluor-1,2-dihydro-2-oxo-3H-indol-3-yliden)methyl]-2,4-dimethyl-1H-pyrrol-3-carboxyamid, fremgangsmåder til fremstilling deraf og sammensætninger deraf - Google Patents

Krystaller indeholdende et malatsyresalt af N-[2-(diethylamino)ethyl]-5-[(5-fluor-1,2-dihydro-2-oxo-3H-indol-3-yliden)methyl]-2,4-dimethyl-1H-pyrrol-3-carboxyamid, fremgangsmåder til fremstilling deraf og sammensætninger deraf

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Publication number
DK1419151T3
DK1419151T3 DK02759342.5T DK02759342T DK1419151T3 DK 1419151 T3 DK1419151 T3 DK 1419151T3 DK 02759342 T DK02759342 T DK 02759342T DK 1419151 T3 DK1419151 T3 DK 1419151T3
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DK
Denmark
Prior art keywords
carboxyamide
ylidene
indol
diethylamino
pyrrole
Prior art date
Application number
DK02759342.5T
Other languages
Danish (da)
English (en)
Inventor
Michael Hawley
Thomas J Fleck
Stephen P Prescott
Mark T Maloney
Original Assignee
Pharmacia & Upjohn Co Llc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23211067&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1419151(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Application granted granted Critical
Publication of DK1419151T3 publication Critical patent/DK1419151T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
DK02759342.5T 2001-08-15 2002-08-13 Krystaller indeholdende et malatsyresalt af N-[2-(diethylamino)ethyl]-5-[(5-fluor-1,2-dihydro-2-oxo-3H-indol-3-yliden)methyl]-2,4-dimethyl-1H-pyrrol-3-carboxyamid, fremgangsmåder til fremstilling deraf og sammensætninger deraf DK1419151T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31235301P 2001-08-15 2001-08-15
PCT/US2002/025649 WO2003016305A1 (en) 2001-08-15 2002-08-13 Crystals including a malic acid salt of n-[2-(diethylamino) ethyl]-5-[(5-fluoro-2-oxo-3h-indole-3-ylidene) methyl]-2, 4-dimethyl-1h-pyrrole-3-carboxamide, processes for its preparation and compositions thereof

Publications (1)

Publication Number Publication Date
DK1419151T3 true DK1419151T3 (da) 2014-03-31

Family

ID=23211067

Family Applications (2)

Application Number Title Priority Date Filing Date
DK02759342.5T DK1419151T3 (da) 2001-08-15 2002-08-13 Krystaller indeholdende et malatsyresalt af N-[2-(diethylamino)ethyl]-5-[(5-fluor-1,2-dihydro-2-oxo-3H-indol-3-yliden)methyl]-2,4-dimethyl-1H-pyrrol-3-carboxyamid, fremgangsmåder til fremstilling deraf og sammensætninger deraf
DK16196036.4T DK3168218T3 (en) 2001-08-15 2002-08-13 Crystalline comprising an L-malic acid salt of N- [2- (DIETHYLAMINO) ETHYL] -5 - [(5-FLUOR-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDE) METHYL] -2,4 -DIMETHYL-1H-PYRROL-3-CARBOXAMIDE FOR USE AS A MEDICINE

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK16196036.4T DK3168218T3 (en) 2001-08-15 2002-08-13 Crystalline comprising an L-malic acid salt of N- [2- (DIETHYLAMINO) ETHYL] -5 - [(5-FLUOR-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDE) METHYL] -2,4 -DIMETHYL-1H-PYRROL-3-CARBOXAMIDE FOR USE AS A MEDICINE

Country Status (42)

Country Link
US (2) US20030069298A1 (https=)
EP (3) EP3168218B1 (https=)
JP (1) JP4159988B2 (https=)
KR (1) KR100639281B1 (https=)
CN (2) CN100364991C (https=)
AP (1) AP1660A (https=)
AR (1) AR036261A1 (https=)
AU (1) AU2002324684B2 (https=)
BG (1) BG108553A (https=)
BR (1) BR0211612A (https=)
CA (1) CA2455050C (https=)
CO (1) CO5550431A2 (https=)
CU (1) CU23713B7 (https=)
CY (1) CY1121552T1 (https=)
CZ (1) CZ2004196A3 (https=)
DK (2) DK1419151T3 (https=)
EA (1) EA006445B9 (https=)
EC (1) ECSP044975A (https=)
ES (3) ES2623094T3 (https=)
GE (1) GEP20063777B (https=)
HR (1) HRP20040112B1 (https=)
HU (1) HU229206B1 (https=)
IL (1) IL160097A0 (https=)
IS (1) IS7147A (https=)
MA (1) MA27058A1 (https=)
ME (1) ME00414B (https=)
MX (1) MXPA04001452A (https=)
MY (1) MY139383A (https=)
NO (1) NO326508B1 (https=)
NZ (1) NZ531232A (https=)
OA (1) OA12650A (https=)
PL (1) PL216524B1 (https=)
PT (2) PT3168218T (https=)
RS (1) RS53251B (https=)
SI (2) SI1419151T1 (https=)
SK (1) SK902004A3 (https=)
TN (1) TNSN04028A1 (https=)
TR (1) TR201900509T4 (https=)
TW (1) TWI269796B (https=)
UA (1) UA76483C2 (https=)
WO (1) WO2003016305A1 (https=)
ZA (1) ZA200400706B (https=)

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Publication number Publication date
TWI269796B (en) 2007-01-01
EP1419151B1 (en) 2014-02-26
US20030069298A1 (en) 2003-04-10
EP2332934B1 (en) 2017-03-01
CA2455050C (en) 2007-02-20
IS7147A (is) 2004-02-10
US20070191458A1 (en) 2007-08-16
EP2332934A1 (en) 2011-06-15
CY1121552T1 (el) 2020-05-29
CZ2004196A3 (cs) 2005-01-12
CN1789264A (zh) 2006-06-21
HU229206B1 (en) 2013-09-30
TNSN04028A1 (fr) 2006-06-01
CN100439360C (zh) 2008-12-03
HK1066542A1 (en) 2005-03-24
HRP20040112A2 (en) 2004-06-30
MXPA04001452A (es) 2004-05-20
KR20040030074A (ko) 2004-04-08
CO5550431A2 (es) 2005-08-31
ZA200400706B (en) 2005-05-25
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KR100639281B1 (ko) 2006-10-31
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NO326508B1 (no) 2008-12-15
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EA006445B9 (ru) 2017-02-28
AR036261A1 (es) 2004-08-25
BG108553A (bg) 2005-04-30
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MA27058A1 (fr) 2004-12-20
RS53251B (sr) 2014-08-29
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CN100364991C (zh) 2008-01-30
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EA006445B1 (ru) 2005-12-29
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EA200400183A1 (ru) 2004-08-26
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PL216524B1 (pl) 2014-04-30
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JP2005503386A (ja) 2005-02-03
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