DK139751C - Analogifremgangsmaade til fremstilling af n-benzhydryl-n'-p-hydroxybenzyl-piperaziner - Google Patents

Analogifremgangsmaade til fremstilling af n-benzhydryl-n'-p-hydroxybenzyl-piperaziner

Info

Publication number
DK139751C
DK139751C DK304673A DK304673A DK139751C DK 139751 C DK139751 C DK 139751C DK 304673 A DK304673 A DK 304673A DK 304673 A DK304673 A DK 304673A DK 139751 C DK139751 C DK 139751C
Authority
DK
Denmark
Prior art keywords
piperazines
benzhydryl
hydroxybenzyl
preparation
analogical procedure
Prior art date
Application number
DK304673A
Other languages
Danish (da)
English (en)
Other versions
DK139751B (da
Inventor
T Raabe
E Schraven
J Scholtholt
R-E Nitz
Original Assignee
Cassella Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2226767A external-priority patent/DE2226767A1/de
Priority claimed from DE19732312212 external-priority patent/DE2312212A1/de
Application filed by Cassella Ag filed Critical Cassella Ag
Publication of DK139751B publication Critical patent/DK139751B/da
Application granted granted Critical
Publication of DK139751C publication Critical patent/DK139751C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205Radicals derived from carbonic acid
DK304673A 1972-06-02 1973-06-01 Analogifremgangsmaade til fremstilling af n-benzhydryl-n'-p-hydroxybenzyl-piperaziner DK139751C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2226767A DE2226767A1 (de) 1972-06-02 1972-06-02 N-benzhydryl-n'-p-hydroxybenzylpiperazin und verfahren zu seiner herstellung
DE19732312212 DE2312212A1 (de) 1973-03-12 1973-03-12 N-(p-chlorbenzhydryl)-n'-p-hydroxybenzyl-piperazin und verfahren zu seiner herstellung

Publications (2)

Publication Number Publication Date
DK139751B DK139751B (da) 1979-04-09
DK139751C true DK139751C (da) 1979-09-17

Family

ID=25763357

Family Applications (1)

Application Number Title Priority Date Filing Date
DK304673A DK139751C (da) 1972-06-02 1973-06-01 Analogifremgangsmaade til fremstilling af n-benzhydryl-n'-p-hydroxybenzyl-piperaziner

Country Status (26)

Country Link
US (1) US3868377A (fi)
JP (1) JPS4948687A (fi)
AR (5) AR196936A1 (fi)
AT (3) AT331801B (fi)
AU (1) AU470393B2 (fi)
BG (3) BG20596A3 (fi)
CA (1) CA980347A (fi)
CH (4) CH574949A5 (fi)
CS (4) CS178429B2 (fi)
DD (1) DD106644A5 (fi)
DK (1) DK139751C (fi)
EG (1) EG11434A (fi)
ES (3) ES415464A1 (fi)
FI (1) FI55656C (fi)
FR (1) FR2186265B1 (fi)
GB (1) GB1386916A (fi)
HU (1) HU165312B (fi)
IE (1) IE37717B1 (fi)
IL (1) IL42384A (fi)
NL (1) NL7306771A (fi)
NO (1) NO138026C (fi)
PH (1) PH9485A (fi)
PL (3) PL94759B1 (fi)
RO (3) RO62900A (fi)
SE (1) SE396385B (fi)
SU (4) SU530644A3 (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59101475A (ja) * 1982-12-02 1984-06-12 Nippon Chemiphar Co Ltd 新規ピペラジン誘導体およびその製造法ならびにこれを含有する脳循環改善剤
HU186656B (en) * 1982-12-28 1985-09-30 Richter Gedeon Vegyeszet Process for producing new benzhydryl-piperazine derivatives, acid additionak salts and pharmaceutical compositions containing them
GB8320701D0 (en) * 1983-08-01 1983-09-01 Wellcome Found Chemotherapeutic agent
JPS60222472A (ja) * 1984-03-30 1985-11-07 Kanebo Ltd 新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物
DE68916126T2 (de) * 1988-08-05 1994-10-27 Nippon Chemiphar Co Optisch aktive Piperazin-Derivate.
FR2661176B1 (fr) * 1990-04-20 1992-06-12 Adir Nouveau procede de preparation de la 1-(2,3,4-trimethoxybenzyl) piperazine en amination reductive.
KR960701033A (ko) * 1993-12-08 1996-02-24 그레그 씨.브라운 효능있는 칼슘 길항 및 산화방지 활성을 모두 갖는 화합물, 및 세포보호제로서 그것의 사용방법(compounds having both potent calcium antagonist and antioxidant activity and use there of as cytoprotective agents)
NZ589492A (en) * 2008-06-02 2012-06-29 Cipla Ltd Processes for the synthesis of levocetirizine and intermediates for use therein

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2709169A (en) * 1955-05-24 X c chs
US3051710A (en) * 1959-12-21 1962-08-28 Lakeside Lab Inc Glycolic acid amide derivatives of piperazine and use thereof

Also Published As

Publication number Publication date
PL97129B1 (pl) 1978-02-28
SU507238A3 (ru) 1976-03-15
FR2186265A1 (fi) 1974-01-11
CS182234B2 (en) 1978-04-28
NO138026C (no) 1978-06-14
AR200764A1 (es) 1974-12-13
GB1386916A (en) 1975-03-12
CS182248B2 (en) 1978-04-28
AT331252B (de) 1976-08-10
SU508196A3 (ru) 1976-03-25
CS178429B2 (fi) 1977-09-15
AR201001A1 (es) 1975-02-06
IL42384A0 (en) 1973-07-30
AT331802B (de) 1976-08-25
CH574949A5 (fi) 1976-04-30
FR2186265B1 (fi) 1976-03-05
AU470393B2 (en) 1976-03-11
PL91050B1 (fi) 1977-02-28
AU5634373A (en) 1974-12-05
FI55656C (fi) 1979-09-10
CH593959A5 (fi) 1977-12-30
DD106644A5 (fi) 1974-06-20
IL42384A (en) 1976-12-31
PL94759B1 (pl) 1977-08-31
RO68378A (ro) 1982-02-01
ES415465A1 (es) 1976-05-16
NO138026B (no) 1978-03-06
CS178430B2 (fi) 1977-09-15
AT331801B (de) 1976-08-25
ATA483073A (de) 1975-12-15
CH579064A5 (fi) 1976-08-31
RO62900A (ro) 1982-10-26
PH9485A (en) 1976-01-08
NL7306771A (fi) 1973-12-04
RO68379A (ro) 1981-11-24
DK139751B (da) 1979-04-09
SU530644A3 (ru) 1976-09-30
AR196936A1 (es) 1974-02-28
ATA483173A (de) 1975-12-15
HU165312B (fi) 1974-08-28
ATA483273A (de) 1975-11-15
BG20371A3 (fi) 1975-11-05
US3868377A (en) 1975-02-25
BG20596A3 (fi) 1975-12-05
IE37717L (en) 1973-12-02
FI55656B (fi) 1979-05-31
ES415464A1 (es) 1976-05-01
CA980347A (en) 1975-12-23
EG11434A (en) 1977-09-30
CH594651A5 (fi) 1978-01-13
AR194688A1 (es) 1973-07-31
ES415466A1 (es) 1976-05-16
SU577995A3 (ru) 1977-10-25
SE396385B (sv) 1977-09-19
AR204987A1 (es) 1976-03-31
JPS4948687A (fi) 1974-05-11
IE37717B1 (en) 1977-09-28
BG20595A3 (fi) 1975-12-05

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