ES415466A1 - Procedimiento para la obtencion de n - benzhidril - n' - p - hidroxibencilpiperazinas. - Google Patents
Procedimiento para la obtencion de n - benzhidril - n' - p - hidroxibencilpiperazinas.Info
- Publication number
- ES415466A1 ES415466A1 ES415466A ES415466A ES415466A1 ES 415466 A1 ES415466 A1 ES 415466A1 ES 415466 A ES415466 A ES 415466A ES 415466 A ES415466 A ES 415466A ES 415466 A1 ES415466 A1 ES 415466A1
- Authority
- ES
- Spain
- Prior art keywords
- piperazines
- benzhydryl
- hydroxybenzyl
- manufacture
- processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2226767A DE2226767A1 (de) | 1972-06-02 | 1972-06-02 | N-benzhydryl-n'-p-hydroxybenzylpiperazin und verfahren zu seiner herstellung |
| DE19732312212 DE2312212A1 (de) | 1973-03-12 | 1973-03-12 | N-(p-chlorbenzhydryl)-n'-p-hydroxybenzyl-piperazin und verfahren zu seiner herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES415466A1 true ES415466A1 (es) | 1976-05-16 |
Family
ID=25763357
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES415466A Expired ES415466A1 (es) | 1972-06-02 | 1973-06-01 | Procedimiento para la obtencion de n - benzhidril - n' - p - hidroxibencilpiperazinas. |
| ES415464A Expired ES415464A1 (es) | 1972-06-02 | 1973-06-01 | Procedimiento para la obtencion de n-benzhidril-n'-p-hidro-xibencil-piperazina. |
| ES73415465A Expired ES415465A1 (es) | 1972-06-02 | 1973-06-01 | Procedimiento para la obtencion de n - benzhidril - n' - p - hidroxibencilpiperazina. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES415464A Expired ES415464A1 (es) | 1972-06-02 | 1973-06-01 | Procedimiento para la obtencion de n-benzhidril-n'-p-hidro-xibencil-piperazina. |
| ES73415465A Expired ES415465A1 (es) | 1972-06-02 | 1973-06-01 | Procedimiento para la obtencion de n - benzhidril - n' - p - hidroxibencilpiperazina. |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US3868377A (es) |
| JP (1) | JPS4948687A (es) |
| AR (5) | AR201001A1 (es) |
| AT (3) | AT331802B (es) |
| AU (1) | AU470393B2 (es) |
| BG (3) | BG20596A3 (es) |
| CA (1) | CA980347A (es) |
| CH (4) | CH593959A5 (es) |
| CS (4) | CS182234B2 (es) |
| DD (1) | DD106644A5 (es) |
| DK (1) | DK139751C (es) |
| EG (1) | EG11434A (es) |
| ES (3) | ES415466A1 (es) |
| FI (1) | FI55656C (es) |
| FR (1) | FR2186265B1 (es) |
| GB (1) | GB1386916A (es) |
| HU (1) | HU165312B (es) |
| IE (1) | IE37717B1 (es) |
| IL (1) | IL42384A (es) |
| NL (1) | NL7306771A (es) |
| NO (1) | NO138026C (es) |
| PH (1) | PH9485A (es) |
| PL (3) | PL91050B1 (es) |
| RO (3) | RO68379A (es) |
| SE (1) | SE396385B (es) |
| SU (4) | SU508196A3 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59101475A (ja) * | 1982-12-02 | 1984-06-12 | Nippon Chemiphar Co Ltd | 新規ピペラジン誘導体およびその製造法ならびにこれを含有する脳循環改善剤 |
| HU186656B (en) * | 1982-12-28 | 1985-09-30 | Richter Gedeon Vegyeszet | Process for producing new benzhydryl-piperazine derivatives, acid additionak salts and pharmaceutical compositions containing them |
| GB8320701D0 (en) * | 1983-08-01 | 1983-09-01 | Wellcome Found | Chemotherapeutic agent |
| JPS60222472A (ja) * | 1984-03-30 | 1985-11-07 | Kanebo Ltd | 新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物 |
| AU617631B2 (en) * | 1988-08-05 | 1991-11-28 | Nippon Chemiphar Co. Ltd. | Optically active piperazine derivative |
| FR2661176B1 (fr) * | 1990-04-20 | 1992-06-12 | Adir | Nouveau procede de preparation de la 1-(2,3,4-trimethoxybenzyl) piperazine en amination reductive. |
| JP3150155B2 (ja) * | 1993-12-08 | 2001-03-26 | アルコン ラボラトリーズ，インコーポレイテッド | 有力なカルシウム拮抗活性および酸化防止活性の両方を有する化合物および細胞保護剤としてのその使用 |
| WO2009147389A2 (en) * | 2008-06-02 | 2009-12-10 | Cipla Limited | Processes for the synthesis of levocetirizine and intermediates for use therein |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2709169A (en) * | 1955-05-24 | X c chs | ||
| US3051710A (en) * | 1959-12-21 | 1962-08-28 | Lakeside Lab Inc | Glycolic acid amide derivatives of piperazine and use thereof |
-
1973
- 1973-05-15 NL NL7306771A patent/NL7306771A/xx not_active Application Discontinuation
- 1973-05-28 IE IE855/73A patent/IE37717B1/xx unknown
- 1973-05-29 CS CS7300003883A patent/CS182234B2/cs unknown
- 1973-05-29 IL IL42384A patent/IL42384A/en unknown
- 1973-05-29 RO RO7382540A patent/RO68379A/ro unknown
- 1973-05-29 US US364764A patent/US3868377A/en not_active Expired - Lifetime
- 1973-05-29 BG BG26972A patent/BG20596A3/xx unknown
- 1973-05-29 BG BG23741A patent/BG20595A3/xx unknown
- 1973-05-29 CS CS7600004284A patent/CS182248B2/cs unknown
- 1973-05-29 BG BG26973A patent/BG20371A3/xx unknown
- 1973-05-29 RO RO7382539A patent/RO68378A/ro unknown
- 1973-05-29 CS CS3878A patent/CS178430B2/cs unknown
- 1973-05-29 RO RO7374944A patent/RO62900A/ro unknown
- 1973-05-29 CS CS3877A patent/CS178429B2/cs unknown
- 1973-05-30 GB GB2571073A patent/GB1386916A/en not_active Expired
- 1973-05-30 SE SE7307692A patent/SE396385B/xx unknown
- 1973-05-31 PL PL1973162986A patent/PL91050B1/pl unknown
- 1973-05-31 EG EG206/73A patent/EG11434A/xx active
- 1973-05-31 SU SU1926943A patent/SU508196A3/ru active
- 1973-05-31 PH PH14678*UA patent/PH9485A/en unknown
- 1973-05-31 PL PL1973186638A patent/PL97129B1/pl unknown
- 1973-05-31 AR AR248327A patent/AR201001A1/es active
- 1973-05-31 JP JP48060375A patent/JPS4948687A/ja active Pending
- 1973-05-31 SU SU1926942A patent/SU530644A3/ru active
- 1973-05-31 AR AR248326A patent/AR194688A1/es active
- 1973-05-31 PL PL1973186639A patent/PL94759B1/pl unknown
- 1973-05-31 HU HUCA347A patent/HU165312B/hu unknown
- 1973-05-31 CA CA172,824A patent/CA980347A/en not_active Expired
- 1973-05-31 SU SU1926939A patent/SU507238A3/ru active
- 1973-05-31 AR AR248325A patent/AR196936A1/es active
- 1973-05-31 AU AU56343/73A patent/AU470393B2/en not_active Expired
- 1973-05-31 DD DD171224A patent/DD106644A5/xx unknown
- 1973-06-01 DK DK304673A patent/DK139751C/da active
- 1973-06-01 ES ES415466A patent/ES415466A1/es not_active Expired
- 1973-06-01 FI FI1797/73A patent/FI55656C/fi active
- 1973-06-01 AT AT483173A patent/AT331802B/de not_active IP Right Cessation
- 1973-06-01 ES ES415464A patent/ES415464A1/es not_active Expired
- 1973-06-01 AT AT483073A patent/AT331801B/de not_active IP Right Cessation
- 1973-06-01 ES ES73415465A patent/ES415465A1/es not_active Expired
- 1973-06-01 AT AT483273A patent/AT331252B/de not_active IP Right Cessation
- 1973-06-01 FR FR7319998A patent/FR2186265B1/fr not_active Expired
- 1973-06-01 NO NO2303/73A patent/NO138026C/no unknown
- 1973-06-04 CH CH803073A patent/CH593959A5/xx not_active IP Right Cessation
- 1973-06-04 CH CH802873A patent/CH574949A5/xx not_active IP Right Cessation
- 1973-06-04 CH CH1193576A patent/CH594651A5/xx not_active IP Right Cessation
- 1973-06-04 CH CH802973A patent/CH579064A5/xx not_active IP Right Cessation
-
1974
- 1974-01-01 AR AR252417A patent/AR204987A1/es active
- 1974-02-18 AR AR252416A patent/AR200764A1/es active
- 1974-12-13 SU SU7402082532A patent/SU577995A3/ru active
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