BG20595A3 - Методл за получаване на n-бензхидрил n-р-хидроксилбензил-пиперазини - Google Patents

Методл за получаване на n-бензхидрил n-р-хидроксилбензил-пиперазини

Info

Publication number
BG20595A3
BG20595A3 BG023741A BG2374173A BG20595A3 BG 20595 A3 BG20595 A3 BG 20595A3 BG 023741 A BG023741 A BG 023741A BG 2374173 A BG2374173 A BG 2374173A BG 20595 A3 BG20595 A3 BG 20595A3
Authority
BG
Bulgaria
Prior art keywords
piperazines
benzhydryl
hydroxybenzyl
preparation
Prior art date
Application number
BG023741A
Other languages
Bulgarian (bg)
English (en)
Inventor
He Пocoчehи
Original Assignee
Cassella Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2226767A external-priority patent/DE2226767A1/de
Priority claimed from DE19732312212 external-priority patent/DE2312212A1/de
Application filed by Cassella Ag filed Critical Cassella Ag
Publication of BG20595A3 publication Critical patent/BG20595A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
BG023741A 1972-06-02 1973-05-29 Методл за получаване на n-бензхидрил n-р-хидроксилбензил-пиперазини BG20595A3 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2226767A DE2226767A1 (de) 1972-06-02 1972-06-02 N-benzhydryl-n'-p-hydroxybenzylpiperazin und verfahren zu seiner herstellung
DE19732312212 DE2312212A1 (de) 1973-03-12 1973-03-12 N-(p-chlorbenzhydryl)-n'-p-hydroxybenzyl-piperazin und verfahren zu seiner herstellung

Publications (1)

Publication Number Publication Date
BG20595A3 true BG20595A3 (bg) 1975-12-05

Family

ID=25763357

Family Applications (3)

Application Number Title Priority Date Filing Date
BG026973A BG20371A3 (bg) 1972-06-02 1973-05-29 Метод за получаване на n-бензхидрил-n'-р- хидробензил-пиперазини
BG023741A BG20595A3 (bg) 1972-06-02 1973-05-29 Методл за получаване на n-бензхидрил n-р-хидроксилбензил-пиперазини
BG026972A BG20596A3 (bg) 1972-06-02 1973-05-29 Метод за получаване на n-бензхидрил-n-р-хидроксибензил-пиперазини

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BG026973A BG20371A3 (bg) 1972-06-02 1973-05-29 Метод за получаване на n-бензхидрил-n'-р- хидробензил-пиперазини

Family Applications After (1)

Application Number Title Priority Date Filing Date
BG026972A BG20596A3 (bg) 1972-06-02 1973-05-29 Метод за получаване на n-бензхидрил-n-р-хидроксибензил-пиперазини

Country Status (26)

Country Link
US (1) US3868377A (xx)
JP (1) JPS4948687A (xx)
AR (5) AR194688A1 (xx)
AT (3) AT331802B (xx)
AU (1) AU470393B2 (xx)
BG (3) BG20371A3 (xx)
CA (1) CA980347A (xx)
CH (4) CH593959A5 (xx)
CS (4) CS178430B2 (xx)
DD (1) DD106644A5 (xx)
DK (1) DK139751C (xx)
EG (1) EG11434A (xx)
ES (3) ES415464A1 (xx)
FI (1) FI55656C (xx)
FR (1) FR2186265B1 (xx)
GB (1) GB1386916A (xx)
HU (1) HU165312B (xx)
IE (1) IE37717B1 (xx)
IL (1) IL42384A (xx)
NL (1) NL7306771A (xx)
NO (1) NO138026C (xx)
PH (1) PH9485A (xx)
PL (3) PL91050B1 (xx)
RO (3) RO68379A (xx)
SE (1) SE396385B (xx)
SU (4) SU508196A3 (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59101475A (ja) * 1982-12-02 1984-06-12 Nippon Chemiphar Co Ltd 新規ピペラジン誘導体およびその製造法ならびにこれを含有する脳循環改善剤
HU186656B (en) * 1982-12-28 1985-09-30 Richter Gedeon Vegyeszet Process for producing new benzhydryl-piperazine derivatives, acid additionak salts and pharmaceutical compositions containing them
GB8320701D0 (en) * 1983-08-01 1983-09-01 Wellcome Found Chemotherapeutic agent
JPS60222472A (ja) * 1984-03-30 1985-11-07 Kanebo Ltd 新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物
US4978666A (en) * 1988-08-05 1990-12-18 Nippon Chemiphar Co., Ltd. Optically active piperazine derivative
FR2661176B1 (fr) * 1990-04-20 1992-06-12 Adir Nouveau procede de preparation de la 1-(2,3,4-trimethoxybenzyl) piperazine en amination reductive.
ES2156934T3 (es) * 1993-12-08 2001-08-01 Alcon Lab Inc Compuestos que presentan una potente actividad de antagonistas del calcio y de antioxidantes y su utilizacion como agentes citoprotectores.
CA2724887A1 (en) * 2008-06-02 2009-12-10 Cipla Limited Processes for the synthesis of levocetirizine and intermediates for use therein

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2709169A (en) * 1955-05-24 X c chs
US3051710A (en) * 1959-12-21 1962-08-28 Lakeside Lab Inc Glycolic acid amide derivatives of piperazine and use thereof

Also Published As

Publication number Publication date
AT331801B (de) 1976-08-25
AR200764A1 (es) 1974-12-13
FR2186265A1 (xx) 1974-01-11
SE396385B (sv) 1977-09-19
IL42384A0 (en) 1973-07-30
IL42384A (en) 1976-12-31
CS178429B2 (xx) 1977-09-15
ATA483273A (de) 1975-11-15
FR2186265B1 (xx) 1976-03-05
RO62900A (ro) 1982-10-26
ES415465A1 (es) 1976-05-16
GB1386916A (en) 1975-03-12
AR201001A1 (es) 1975-02-06
SU507238A3 (ru) 1976-03-15
AT331252B (de) 1976-08-10
AU5634373A (en) 1974-12-05
CS182234B2 (en) 1978-04-28
PL94759B1 (pl) 1977-08-31
FI55656B (fi) 1979-05-31
CH579064A5 (xx) 1976-08-31
RO68379A (ro) 1981-11-24
CA980347A (en) 1975-12-23
BG20596A3 (bg) 1975-12-05
ATA483073A (de) 1975-12-15
ES415464A1 (es) 1976-05-01
CS178430B2 (xx) 1977-09-15
AR196936A1 (es) 1974-02-28
AR204987A1 (es) 1976-03-31
DD106644A5 (xx) 1974-06-20
PL91050B1 (xx) 1977-02-28
HU165312B (xx) 1974-08-28
IE37717L (en) 1973-12-02
DK139751B (da) 1979-04-09
SU508196A3 (ru) 1976-03-25
SU577995A3 (ru) 1977-10-25
NO138026B (no) 1978-03-06
US3868377A (en) 1975-02-25
AU470393B2 (en) 1976-03-11
CH594651A5 (xx) 1978-01-13
CS182248B2 (en) 1978-04-28
NL7306771A (xx) 1973-12-04
PL97129B1 (pl) 1978-02-28
NO138026C (no) 1978-06-14
IE37717B1 (en) 1977-09-28
ES415466A1 (es) 1976-05-16
PH9485A (en) 1976-01-08
DK139751C (da) 1979-09-17
FI55656C (fi) 1979-09-10
AT331802B (de) 1976-08-25
CH593959A5 (xx) 1977-12-30
CH574949A5 (xx) 1976-04-30
ATA483173A (de) 1975-12-15
AR194688A1 (es) 1973-07-31
EG11434A (en) 1977-09-30
SU530644A3 (ru) 1976-09-30
RO68378A (ro) 1982-02-01
BG20371A3 (bg) 1975-11-05
JPS4948687A (xx) 1974-05-11

Similar Documents

Publication Publication Date Title
SE407579B (sv) Forfarande for framstellning av n-fosfonometylglycin
NO140731C (no) Fremgangsmaate for fremstilling av dimetyleter
IT978445B (it) Metodo per la preparazione di ammidosilani
SE382053B (sv) Forfarande for framstellning av bifenylylalkanoylaminopyridiner
BG20609A3 (bg) Метод за получаване на 7-алфа-хидрокси-алфа-фенил(ацетамидо-3/1- метил-1н-тетразол-5-илтиометил)-3-цефем-4-карбонова киселина
BG21028A3 (bg) Метод за получаване на амино-бензимидазоли
SE383151B (sv) Forfarande for framstellning av 1-hydroxi-2-pyridoner
IT1002359B (it) Metodo di preparazione di alchilati
BG22816A3 (bg) Метод за получаване на 2-алкиламино-дихидропиридини
BG20596A3 (bg) Метод за получаване на n-бензхидрил-n-р-хидроксибензил-пиперазини
SE380272B (sv) Forfarande for framstellning av n-fosfonmetylglycin
SE393111B (sv) Forfarande for framstellning av d-2-halogen-6-metyl-8-substituerad - ergolin
RO69492A2 (ro) Procedeu pentru prepararea perclor-metil-mercaptanului
FI56830B (fi) Foerfarande foer framstaellning av asparaginylgrupper innehaollande biologiskt aktiva polypeptider
SE393808B (sv) Forfarande for framstellning av isomaltit
BG20570A3 (bg) Метод за получаване на n-(етан-2-ол)-2-метокси-4-ацетамино-5- хлорбензамид
BG20097A3 (bg) Метод за получаване на 2-алкокси-5-алкилсулфонил-бензоени киселини
AR197040A1 (es) Procedimiento de preparacion de nuevas bifenilacetamidas
BG20583A3 (bg) Метод за получаване на 2,6-диамино-дихидропиридини
AR202672A1 (es) Metodo para la preparacion de tiaxantenos fluorsustituidos
SE391717B (sv) Forfarande for framstellning av 4-aryl-5-aminoalkyl-4-oxazolin-2-oner
IT996099B (it) Procedimento di preparazione di amminoantrachinone
BG19804A3 (bg) Метод за получаване на 4-или-5-нитроимидазоли
BG20795A3 (bg) Метод за получаване на триазинобензимидазоли
SE389862B (sv) Forfarande for framstellning av alfa-6-deoxitetracykliner