DK1307564T3 - Forbindelser og fremgangsmåde til behandling og diagnose af chlamydiainfektion - Google Patents

Forbindelser og fremgangsmåde til behandling og diagnose af chlamydiainfektion

Info

Publication number
DK1307564T3
DK1307564T3 DK01959114T DK01959114T DK1307564T3 DK 1307564 T3 DK1307564 T3 DK 1307564T3 DK 01959114 T DK01959114 T DK 01959114T DK 01959114 T DK01959114 T DK 01959114T DK 1307564 T3 DK1307564 T3 DK 1307564T3
Authority
DK
Denmark
Prior art keywords
polypeptides
compounds
methods
treating
dna sequences
Prior art date
Application number
DK01959114T
Other languages
Danish (da)
English (en)
Inventor
Steven P Fling
Yasir A W Skeiky
Peter Probst
Ajay Bhatia
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/620,412 external-priority patent/US6448234B1/en
Application filed by Corixa Corp filed Critical Corixa Corp
Application granted granted Critical
Publication of DK1307564T3 publication Critical patent/DK1307564T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/295Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Chlamydiales (O)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/461Cellular immunotherapy characterised by the cell type used
    • A61K39/4611T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/461Cellular immunotherapy characterised by the cell type used
    • A61K39/4615Dendritic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/462Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4622Antigen presenting cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/464Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4648Bacterial antigens
    • A61K39/464835Chlamydiaceae, e.g. Chlamydia trachomatis or Chlamydia psittaci
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5154Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK01959114T 2000-07-20 2001-07-20 Forbindelser og fremgangsmåde til behandling og diagnose af chlamydiainfektion DK1307564T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/620,412 US6448234B1 (en) 1998-12-08 2000-07-20 Compounds and methods for treatment and diagnosis of chlamydial infection
US09/841,132 US20020061848A1 (en) 2000-07-20 2001-04-23 Compounds and methods for treatment and diagnosis of chlamydial infection
PCT/US2001/023121 WO2002008267A2 (fr) 2000-07-20 2001-07-20 Composes et methodes de traitement et de diagnostic de l'infection a chlamydia

Publications (1)

Publication Number Publication Date
DK1307564T3 true DK1307564T3 (da) 2007-12-27

Family

ID=27088713

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01959114T DK1307564T3 (da) 2000-07-20 2001-07-20 Forbindelser og fremgangsmåde til behandling og diagnose af chlamydiainfektion

Country Status (25)

Country Link
US (9) US20020061848A1 (fr)
EP (1) EP1307564B1 (fr)
JP (1) JP2004513622A (fr)
KR (1) KR20030016423A (fr)
CN (1) CN100467600C (fr)
AT (1) ATE373092T1 (fr)
AU (2) AU2001280702B8 (fr)
BR (1) BR0112602A (fr)
CA (1) CA2418282A1 (fr)
CY (1) CY1107796T1 (fr)
CZ (1) CZ2003480A3 (fr)
DE (1) DE60130468T2 (fr)
DK (1) DK1307564T3 (fr)
ES (1) ES2294018T3 (fr)
HK (1) HK1067381A1 (fr)
HU (1) HUP0400477A3 (fr)
IL (2) IL153904A0 (fr)
MX (1) MXPA03000564A (fr)
NO (1) NO20030252L (fr)
NZ (3) NZ541013A (fr)
PL (1) PL209107B1 (fr)
PT (1) PT1307564E (fr)
RU (2) RU2003104976A (fr)
WO (1) WO2002008267A2 (fr)
ZA (1) ZA200300719B (fr)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629167A (en) * 1994-04-19 1997-05-13 Biocine S.P.A. Detection of antibodies against Chlamydia trachomatis pgp3 antigen in patient sera by enzyme-linked immunosorbent assay
US7459524B1 (en) 1997-10-02 2008-12-02 Emergent Product Development Gaithersburg Inc. Chlamydia protein, sequence and uses thereof
US6686339B1 (en) 1998-08-20 2004-02-03 Aventis Pasteur Limited Nucleic acid molecules encoding inclusion membrane protein C of Chlamydia
WO2000011180A1 (fr) 1998-08-20 2000-03-02 Connaught Laboratories Limited MOLECULES D'ACIDE NUCLEIQUE CODANT LA PROTEINE POMP91A DE $i(CHLAMYDIA)
AU5366099A (en) 1998-08-20 2000-03-14 Connaught Laboratories Limited Nucleic acid molecules encoding inclusion membrane protein of (chlamydia)
US6649370B1 (en) 1998-10-28 2003-11-18 Aventis Pasteur Limited Chlamydia antigens and corresponding DNA fragments and uses thereof
US6607730B1 (en) 1998-11-02 2003-08-19 Aventis Pasteur Limited/Aventis Pasteur Limitee Chlamydia antigens and corresponding DNA fragments and uses thereof
WO2000032784A1 (fr) 1998-12-01 2000-06-08 Aventis Pasteur Limited Antigenes de chlamydia et fragments d'adn correspondants et leur utilisation
US6555115B1 (en) * 1998-12-08 2003-04-29 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US20080213264A1 (en) * 1998-12-08 2008-09-04 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US20020061848A1 (en) * 2000-07-20 2002-05-23 Ajay Bhatia Compounds and methods for treatment and diagnosis of chlamydial infection
WO2000034483A2 (fr) 1998-12-08 2000-06-15 Corixa Corporation Composes et procedes pour le traitement et le diagnostic d'infections par le chlamydia
GB9828000D0 (en) 1998-12-18 1999-02-10 Chiron Spa Antigens
US7297341B1 (en) 1998-12-23 2007-11-20 Sanofi Pasteur Limited Chlamydia antigens and corresponding DNA fragments and uses thereof
US6808713B1 (en) 1998-12-28 2004-10-26 Aventis Pasteur Limited Chlamydia antigens and corresponding DNA fragments and uses thereof
CA2356057A1 (fr) 1998-12-28 2000-07-06 Aventis Pasteur Limited Antigenes a chlamydia, fragments d'adn correspondants et leurs utilisations
GB9902555D0 (en) 1999-02-05 1999-03-24 Neutec Pharma Plc Medicament
JP4832646B2 (ja) 1999-03-12 2011-12-07 サノフィ、パストゥール、リミテッド クラミジア抗原および対応するdna断片ならびにその使用
JP4695763B2 (ja) 1999-05-03 2011-06-08 サノフィ、パストゥール、リミテッド クラミジア抗原および対応するdna断片ならびにその使用
DE60037900T2 (de) 1999-09-20 2009-02-12 Sanofi Pasteur Ltd., Toronto Chlamydia antigene und entsprechende dna-fragmente und ihre verwendungen
US6632663B1 (en) 1999-09-22 2003-10-14 Aventis Pasteur Limited DNA immunization against chlamydia infection
EP1240331B1 (fr) 1999-12-22 2010-04-07 Aventis Pasteur Limited Antigenes anti- chlamydia, fragments d'adn correspondants et leurs utilisations
US20030175700A1 (en) 2000-04-21 2003-09-18 Ajay Bhatia Compounds and methods for treatment and diagnosis of chlamydial infection
US6919187B2 (en) * 2000-04-21 2005-07-19 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
EP1282718B1 (fr) 2000-05-08 2006-12-20 Sanofi Pasteur Limited Antigenes de chlamydia, fragments d'adn correspondants et utilisations de tels antigenes
AU2001276619A1 (en) 2000-07-03 2002-01-14 Chiron S.P.A. Immunisation against chlamydia pneumoniae
US7537772B1 (en) * 2000-10-02 2009-05-26 Emergent Product Development Gaithersburg Inc. Chlamydia protein, gene sequence and the uses thereof
US7731980B2 (en) * 2000-10-02 2010-06-08 Emergent Product Development Gaithersburg Inc. Chlamydia PMP proteins, gene sequences and uses thereof
US20030059896A1 (en) * 2000-12-21 2003-03-27 Shire Biochem Inc. Novel chlamydia antigens and corresponding DNA fragments
GB2370838A (en) * 2001-01-06 2002-07-10 Benedikt Timmerman Immunogenic complex
CA2469620A1 (fr) * 2001-12-12 2003-06-19 Chiron Srl. Immunisation contre chlamydia trachomatis
GB0203403D0 (en) 2002-02-13 2002-04-03 Chiron Spa Chlamydia cytotoxic-T cell epitopes
JP4896715B2 (ja) * 2003-06-26 2012-03-14 ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド Chlamydiatrachomatisに対する免疫原性組成物
AU2004291576A1 (en) * 2003-11-20 2005-06-02 Sanofi Pasteur Limited Immunization against Chlamydia infection
US8541007B2 (en) 2005-03-31 2013-09-24 Glaxosmithkline Biologicals S.A. Vaccines against chlamydial infection
EP2392348A3 (fr) * 2005-03-31 2012-01-18 GlaxoSmithKline Biologicals S.A. Vaccins contre l'infection à chlamydia
CN101238146A (zh) * 2005-05-12 2008-08-06 诺华疫苗和诊断有限公司 砂眼衣原体的免疫原性组合物
WO2007030879A1 (fr) * 2005-09-13 2007-03-22 Diatech Pty Ltd Marqueurs diagnostiques et leurs utilisations
WO2007082105A2 (fr) * 2006-01-16 2007-07-19 Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Vaccin contre chlamydia
EP1970708A1 (fr) * 2007-03-07 2008-09-17 Mikrogen Molekularbiologische Entwicklungs-GmbH Biopuce et procédé destiné à la vérification sélective d'infections à chlamydiose
EP2162460A4 (fr) * 2007-06-14 2012-06-06 Emergent Product Dev Gaithersburg Inc Vaccins destinés à lutter contre une infection à chlamydia
WO2009020553A2 (fr) 2007-08-03 2009-02-12 President And Fellows Of Harvard College Antigènes chlamydiens
AU2008331800A1 (en) * 2007-12-03 2009-06-11 President And Fellows Of Harvard College Chlamydia antigens
EP2403526B1 (fr) 2009-03-06 2019-05-15 GlaxoSmithKline Biologicals SA Antigènes de chlamydia
EP2557156B1 (fr) 2010-03-23 2015-02-11 Wako Pure Chemical Industries, Ltd. Amorce et sonde conçues pour détecter chlamydia trachomatis et procédé de détection de chlamydia trachomatis les utilisant
EP2629793A4 (fr) * 2010-10-20 2014-05-28 Genocea Biosciences Inc Antigènes de chlamydia et leurs utilisations
US20130095487A1 (en) * 2011-10-18 2013-04-18 University Of South Florida Interferon-Gamma Response as a Diagnostic Test for Persistent Chlamydial Infections
RU2631002C2 (ru) * 2012-12-05 2017-09-15 Тевакс Дженетикс Вэксин Ко., Лтд. Слитые белки для применения в качестве иммуногенных усиливающих агентов для индуцирования антигенспецифического т-клеточного ответа
CN113801191B (zh) * 2021-08-18 2022-05-17 南京大学 一种检测衣原体的多肽探针及其应用

Family Cites Families (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4118469A (en) * 1976-04-27 1978-10-03 Research Corporation Antigen for trachoma lymphogranuloma venereum (LGV) and non-gonococcal urethritis (NGU)
US4497899A (en) * 1982-04-12 1985-02-05 Abbott Laboratories Immunoassay for Chlamydia trachomatis antigens
US4497900A (en) 1982-04-12 1985-02-05 Abbott Laboratories Immunoassay for Neisseria gonorrhoeae antigens
US4497863A (en) * 1984-03-07 1985-02-05 Milliken Research Corporation Laminated weft insertion fabric
DE3650571T2 (de) 1985-01-14 1997-02-27 Chiron Corp Hauptprotein der Aussenmembran von Chlamydia
US5785973A (en) * 1988-02-01 1998-07-28 Praxis Biologics, Inc. Synthetic peptides representing a T-cell epitope as a carrier molecule for conjugate vaccines
EP0348725A3 (fr) 1988-06-29 1990-10-24 Miles Inc. Epitode spécifique de l'espèce de chlamydia trachomatis et les anticorps le reconnaissant
DE69020143T2 (de) * 1989-02-17 1996-01-25 Chiron Mimotopes Pty Ltd Verfahren zur verwendung und herstellung von peptiden.
US5869608A (en) 1989-03-17 1999-02-09 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and amino acid sequences of the four variable domains of the major outer membrane proteins of Chlamydia trachomatis
US5166053A (en) * 1990-02-23 1992-11-24 Miles Inc. Specimen adequacy control for chlamydia assays
JP3018553B2 (ja) * 1990-05-08 2000-03-13 日立化成工業株式会社 クラミジア・トラコマティス抗体測定方法及びクラミジア・トラコマティス感染症診断用製剤
US5725863A (en) 1991-09-06 1998-03-10 The United States Of America As Represented By The Secretary Of Agriculture Polypeptides useful in prevention of chlamydia infection
DE69327599T2 (de) 1992-06-25 2000-08-10 Smithkline Beecham Biolog Adjuvantien enthaltende Impfstoffzusammensetzung
WO1994006827A1 (fr) 1992-09-18 1994-03-31 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Vaccin a peptide synthetique contre le chlamydia trachomatis
US5549978A (en) * 1992-10-30 1996-08-27 Kabushiki Kaisha Toshiba Magnetoresistance effect element
US5629167A (en) * 1994-04-19 1997-05-13 Biocine S.P.A. Detection of antibodies against Chlamydia trachomatis pgp3 antigen in patient sera by enzyme-linked immunosorbent assay
US6165478A (en) 1994-09-20 2000-12-26 Hitachi Chemical Company, Ltd. DNA encoding Chlamydia pneumoniae antigenic polypeptide
GB9506863D0 (en) 1995-04-03 1995-05-24 Smithkline Beecham Biolog Vaccines
GB9626864D0 (en) 1996-12-24 1997-02-12 Smithkline Beecham Biolog Vaccine
GB9516293D0 (en) 1995-08-09 1995-10-11 Immunova Ltee Novel peptides and their use as vaccines
CN1223589A (zh) * 1996-05-06 1999-07-21 美国拜尔公司 包含鹦鹉热衣原体的猫疫苗及其制备方法
NZ334114A (en) 1996-07-12 2000-06-23 Univ Manitoba DNA immunization against chlamydia infection comprising a major outer membrane protein (MOMP) or a MOMP fragment linked to a promoter sequence
US6464979B1 (en) 1996-09-12 2002-10-15 Aventis Pasteur Limited Chlamydial vaccines and methods of preparation thereof
WO2001023604A2 (fr) 1999-09-28 2001-04-05 Infectio Diagnostic (I.D.I.) Inc. Genes a fort pouvoir de conservation et leur utilisation pour produire des sondes d'acide nucleique specifiques a l'espece, specifiques au gene, specifiques a la famille, specifiques au groupe et universelles et des sondes d'amplification, en vue de detecter et d'identifier rapidement des micro-organismes algaires, archeoba
US7459524B1 (en) * 1997-10-02 2008-12-02 Emergent Product Development Gaithersburg Inc. Chlamydia protein, sequence and uses thereof
JP4249279B2 (ja) 1997-10-22 2009-04-02 デンカ生研株式会社 クラミジア・トラコマティス主要外膜蛋白質及びその製造方法、並びにクラミジア・トラコマティスの抗体測定方法及び抗体測定試薬
ATE352624T1 (de) 1997-11-21 2007-02-15 Serono Genetics Inst Sa Chlamydia pneumoniae genomische sequenzen und polypeptiden, fragmenten und anwendungen davon für nachweis, prevention und heilung
ATE480625T1 (de) * 1997-11-21 2010-09-15 Merck Serono Biodevelopment Äusseres membranpolypeptid von chlamydia pneumoniae sowie fragmente davon und deren verwendung, insbesondere zur diagnose, prävention und behandlung einer infektion
US7041490B1 (en) * 1997-11-28 2006-05-09 Serono Genetics Institute, S.A. Chlamydia trachomatis polynucleotides and vectors, recombinant host cells, DNA chips or kits containing the same
EP2228385A1 (fr) * 1997-11-28 2010-09-15 Merck Serono Biodevelopment Séquence génomique de Chlamydia pneumoniae, polypeptides, fragments et leurs utilisations, en particulier pour le diagnostic, la prévention et le traitement de l'infection
NZ507378A (en) 1998-04-07 2002-12-20 Corixa Corp Fusion proteins of mycobacterium tuberculosis antigens and their uses
CZ301212B6 (cs) * 1998-10-16 2009-12-09 Smithkline Beecham Biologicals S. A. Vakcinacní prostredek
US6607730B1 (en) 1998-11-02 2003-08-19 Aventis Pasteur Limited/Aventis Pasteur Limitee Chlamydia antigens and corresponding DNA fragments and uses thereof
JP2002529069A (ja) 1998-11-12 2002-09-10 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア クラミジア・ニューモニエのゲノム配列
US20080213264A1 (en) 1998-12-08 2008-09-04 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US20020061848A1 (en) * 2000-07-20 2002-05-23 Ajay Bhatia Compounds and methods for treatment and diagnosis of chlamydial infection
US6448234B1 (en) * 1998-12-08 2002-09-10 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US6447779B1 (en) * 1998-12-08 2002-09-10 Corixa Corporation Compounds for the diagnosis of Chlamydial infection
WO2000034483A2 (fr) * 1998-12-08 2000-06-15 Corixa Corporation Composes et procedes pour le traitement et le diagnostic d'infections par le chlamydia
US6432916B1 (en) * 1998-12-08 2002-08-13 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US6555115B1 (en) * 1998-12-08 2003-04-29 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US6565856B1 (en) * 1998-12-08 2003-05-20 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US6166177A (en) * 1998-12-08 2000-12-26 Corixa Corporation Compounds and methods for the treatment and diagnosis of chlamydial infection
GB9828000D0 (en) 1998-12-18 1999-02-10 Chiron Spa Antigens
GB9902555D0 (en) 1999-02-05 1999-03-24 Neutec Pharma Plc Medicament
JP4832646B2 (ja) 1999-03-12 2011-12-07 サノフィ、パストゥール、リミテッド クラミジア抗原および対応するdna断片ならびにその使用
JP4695763B2 (ja) 1999-05-03 2011-06-08 サノフィ、パストゥール、リミテッド クラミジア抗原および対応するdna断片ならびにその使用
US6811783B1 (en) 1999-09-07 2004-11-02 Aventis Pasteur Limited Immunogenic compositions for protection against chlamydial infection
DE60037900T2 (de) 1999-09-20 2009-02-12 Sanofi Pasteur Ltd., Toronto Chlamydia antigene und entsprechende dna-fragmente und ihre verwendungen
US6632663B1 (en) 1999-09-22 2003-10-14 Aventis Pasteur Limited DNA immunization against chlamydia infection
AU4503201A (en) * 1999-10-14 2001-06-12 University Of Utah Research Foundation Resonant optical cavities for high-sensitivity, high-throughput biological sensors and methods
AU1481001A (en) 1999-11-19 2001-05-30 Michigan State University Recombinant chlamydia vaccine
EP1240331B1 (fr) 1999-12-22 2010-04-07 Aventis Pasteur Limited Antigenes anti- chlamydia, fragments d'adn correspondants et leurs utilisations
US20010048927A1 (en) * 2000-02-01 2001-12-06 Richard Stephens Porin B (PorB) as a therapeutic target for prevention and treatment of infection by chlamydia
US20030175700A1 (en) * 2000-04-21 2003-09-18 Ajay Bhatia Compounds and methods for treatment and diagnosis of chlamydial infection
US6919187B2 (en) 2000-04-21 2005-07-19 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
US20020146776A1 (en) * 2000-04-21 2002-10-10 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
EP1282718B1 (fr) 2000-05-08 2006-12-20 Sanofi Pasteur Limited Antigenes de chlamydia, fragments d'adn correspondants et utilisations de tels antigenes
WO2001099156A1 (fr) * 2000-06-16 2001-12-27 Applied Materials, Inc. Nettoyeur carrousel reconfigurable integre pour nettoyage au mouille ou a sec d'un substrat
AU2001276619A1 (en) 2000-07-03 2002-01-14 Chiron S.P.A. Immunisation against chlamydia pneumoniae
US6827189B2 (en) * 2000-07-20 2004-12-07 Zf Friedrichshafen Ag Electromagnetically actuated, single-surface friction coupling, without a rotor slip ring
US7537772B1 (en) 2000-10-02 2009-05-26 Emergent Product Development Gaithersburg Inc. Chlamydia protein, gene sequence and the uses thereof
US7731980B2 (en) 2000-10-02 2010-06-08 Emergent Product Development Gaithersburg Inc. Chlamydia PMP proteins, gene sequences and uses thereof
GB0103169D0 (en) * 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
AU2002306849A1 (en) * 2001-03-21 2002-10-08 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
WO2002079244A2 (fr) 2001-03-30 2002-10-10 University Of Manitoba Facteur d'activite a chlamydia du type protease responsable de la degradation du facteur de transcription de l'hote
US20030199438A1 (en) * 2001-04-09 2003-10-23 Shaw Allan Christian Method for identification of proteins from intracellular bacteria
US20040029129A1 (en) * 2001-10-25 2004-02-12 Liangsu Wang Identification of essential genes in microorganisms
CA2469620A1 (fr) * 2001-12-12 2003-06-19 Chiron Srl. Immunisation contre chlamydia trachomatis
US7105171B2 (en) * 2002-03-07 2006-09-12 The Regents Of The University Of California Porin B (PorB) as a therapeutic target for prevention and treatment of infection by Chlamydia
JP4896715B2 (ja) * 2003-06-26 2012-03-14 ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド Chlamydiatrachomatisに対する免疫原性組成物
FR2869057B1 (fr) * 2004-04-16 2006-06-02 Piscines Desjoyaux Sa Sa Dispositif pour la realisation d'un haut de chainage d'un escalier
SI1812058T1 (sl) * 2004-10-25 2013-02-28 Statens Serum Institut Antigeni chlamidia trachomatis za cepivo in diagnostiäśno rabo
US8541007B2 (en) * 2005-03-31 2013-09-24 Glaxosmithkline Biologicals S.A. Vaccines against chlamydial infection
EP2392348A3 (fr) * 2005-03-31 2012-01-18 GlaxoSmithKline Biologicals S.A. Vaccins contre l'infection à chlamydia
CN101238146A (zh) * 2005-05-12 2008-08-06 诺华疫苗和诊断有限公司 砂眼衣原体的免疫原性组合物
AU2006341122B2 (en) * 2005-12-22 2013-08-22 Novartis Vaccines And Diagnostics, Srl. Chlamydial antigens
WO2007082105A2 (fr) * 2006-01-16 2007-07-19 Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Vaccin contre chlamydia
US20080124338A1 (en) * 2006-09-22 2008-05-29 The Scripps Research Institute Methods for treatment of inflammatory disease and chlamydia infectious disease
CA2664236A1 (fr) 2006-10-04 2008-04-10 Glaxosmithkline Biologicals S.A. Vaccins contre l'infection a chlamydia
US7892567B2 (en) * 2007-10-01 2011-02-22 Board Of Regents, The University Of Texas System Methods and compositions for immunization against chlamydial infection and disease
WO2010042206A1 (fr) * 2008-10-09 2010-04-15 Board Of Regents, University Of Texas System Méthodes et compositions pour antigènes de chlamydia utilisées dans le diagnostic et le traitement de maladies et d'infections à chlamydia
JP2012512257A (ja) * 2008-12-17 2012-05-31 ジェノセア バイオサイエンシーズ, インコーポレイテッド クラミジア抗原およびその使用
EP2403526B1 (fr) * 2009-03-06 2019-05-15 GlaxoSmithKline Biologicals SA Antigènes de chlamydia
WO2011112670A2 (fr) * 2010-03-09 2011-09-15 Board Of Regents, University Of Texas System Procédés et compositions pour antigènes de chlamydia dans le diagnostic et le traitement d'infections et de maladies à chlamydia

Also Published As

Publication number Publication date
CN100467600C (zh) 2009-03-11
HUP0400477A3 (en) 2010-01-28
MXPA03000564A (es) 2004-12-13
EP1307564B1 (fr) 2007-09-12
US20110142872A1 (en) 2011-06-16
AU2001280702B8 (en) 2008-02-28
RU2003104976A (ru) 2004-07-10
IL153904A (en) 2010-04-29
EP1307564A2 (fr) 2003-05-07
RU2006120003A (ru) 2007-12-27
JP2004513622A (ja) 2004-05-13
DE60130468D1 (de) 2007-10-25
US20080181918A1 (en) 2008-07-31
US7462357B2 (en) 2008-12-09
NO20030252D0 (no) 2003-01-17
WO2002008267A3 (fr) 2003-02-27
CN1489628A (zh) 2004-04-14
HK1067381A1 (en) 2005-04-08
US20080299142A1 (en) 2008-12-04
PL365951A1 (en) 2005-01-24
DE60130468T2 (de) 2008-04-03
ES2294018T3 (es) 2008-04-01
IL153904A0 (en) 2003-07-31
BR0112602A (pt) 2004-02-17
US20040234536A1 (en) 2004-11-25
NZ541013A (en) 2007-05-31
US20080317772A1 (en) 2008-12-25
US20090028887A1 (en) 2009-01-29
WO2002008267A2 (fr) 2002-01-31
CY1107796T1 (el) 2013-06-19
NZ523628A (en) 2005-08-26
US8263089B2 (en) 2012-09-11
ZA200300719B (en) 2004-10-27
US8052975B2 (en) 2011-11-08
HUP0400477A2 (hu) 2004-05-28
NO20030252L (no) 2003-03-14
AU2001280702B2 (en) 2008-01-24
NZ549873A (en) 2008-06-30
US20090035296A1 (en) 2009-02-05
US20020061848A1 (en) 2002-05-23
KR20030016423A (ko) 2003-02-26
PL209107B1 (pl) 2011-07-29
ATE373092T1 (de) 2007-09-15
AU2001280702B9 (en) 2002-02-05
PT1307564E (pt) 2007-11-21
WO2002008267A9 (fr) 2006-09-28
US20120114684A1 (en) 2012-05-10
RU2410394C2 (ru) 2011-01-27
CZ2003480A3 (cs) 2003-09-17
AU8070201A (en) 2002-02-05
CA2418282A1 (fr) 2002-01-31

Similar Documents

Publication Publication Date Title
DK1307564T3 (da) Forbindelser og fremgangsmåde til behandling og diagnose af chlamydiainfektion
NO20012812D0 (no) Forbindelser og fremgangsmåter for behandling og diagnose av chlamydiainfeksjon
NZ518917A (en) Compounds and methods for treatment and diagnosis of chlamydial infection
DE60133190D1 (de) Verbindungen und verfahren zur behandlung und diagnose von chlamydia-infektionen
WO1998042740A3 (fr) COMPOSES ET PROCEDES DE DIAGNOSTIC ET DE TRAITEMENT DE L'INFECTION PAR $i(EHRLICHIA)
WO2003041560A3 (fr) Composes et methodes permettant de traiter et de diagnostiquer l'infection a chlamydia
WO2000000615A3 (fr) COMPOSES ET PROCEDES SERVANT A DIAGNOSTIQUER ET A TRAITER L'INFECTION PAR $i(EHRLICHIA)
ATE349533T1 (de) Zusammensetzung zur diagnose und behandlung von herpes simplex virusinfektionen
WO2001085949A3 (fr) Composes et procedes de diagnostic et de traitement de l'infection par une ehrlichia
EP0834567A3 (fr) Composés et méthodes pour le diagnostique et le traitement d'infections à Babesia microti
WO2002053016A3 (fr) Composes et methodes permettant de diagnostiquer et de traiter une infection par babesia
WO2003020108A3 (fr) Compositions et procedes destines a diagnostiquer et a traiter une infection par le virus de l'herpes simplex
WO2001085947A3 (fr) Composes et techniques destines au diagnostic et au traitement de l'infection par b. microti