DK1282619T3 - Fremgangsmåde til fremstilling af thiazolidindionderivater og mellemprodukter - Google Patents

Fremgangsmåde til fremstilling af thiazolidindionderivater og mellemprodukter

Info

Publication number
DK1282619T3
DK1282619T3 DK01931561T DK01931561T DK1282619T3 DK 1282619 T3 DK1282619 T3 DK 1282619T3 DK 01931561 T DK01931561 T DK 01931561T DK 01931561 T DK01931561 T DK 01931561T DK 1282619 T3 DK1282619 T3 DK 1282619T3
Authority
DK
Denmark
Prior art keywords
formula
preparation
intermediates
thiazolidinedione derivatives
compounds
Prior art date
Application number
DK01931561T
Other languages
Danish (da)
English (en)
Inventor
Michelangelo Scalone
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK1282619T3 publication Critical patent/DK1282619T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK01931561T 2000-04-14 2001-04-04 Fremgangsmåde til fremstilling af thiazolidindionderivater og mellemprodukter DK1282619T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00108303 2000-04-14
EP01931561A EP1282619B1 (en) 2000-04-14 2001-04-04 Processes for the preparation of thiazolidinedione derivatives and intermediates

Publications (1)

Publication Number Publication Date
DK1282619T3 true DK1282619T3 (da) 2005-10-17

Family

ID=8168486

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01931561T DK1282619T3 (da) 2000-04-14 2001-04-04 Fremgangsmåde til fremstilling af thiazolidindionderivater og mellemprodukter

Country Status (14)

Country Link
US (3) US6531609B2 (zh)
EP (1) EP1282619B1 (zh)
JP (1) JP2003531146A (zh)
KR (1) KR100519132B1 (zh)
CN (1) CN1231482C (zh)
AT (1) ATE298336T1 (zh)
AU (1) AU2001258306A1 (zh)
CA (1) CA2402374A1 (zh)
DE (1) DE60111634T2 (zh)
DK (1) DK1282619T3 (zh)
ES (1) ES2243493T3 (zh)
JO (1) JO2240B1 (zh)
MX (1) MXPA02010022A (zh)
WO (1) WO2001079202A1 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002080913A1 (en) * 2001-04-06 2002-10-17 F. Hoffmann-La Roche Ag Thiazolidinediones alone or in combination with other therapeutic agents for inhibiting or reducing tumour growth
US7361711B2 (en) * 2001-09-13 2008-04-22 Acushnet Company Compositions for use in golf balls
EP1641790A1 (en) * 2003-06-26 2006-04-05 F. Hoffmann-La Roche Ag Process for the preparation of insulin sensitizer and intermediate compound thereof
KR100796093B1 (ko) 2003-07-02 2008-01-21 에프. 호프만-라 로슈 아게 티아졸 고리로 치환된 인돌릴 유도체 및 ppar조절제로서 그의 용도
CN102746290B (zh) * 2012-06-21 2014-08-27 成都苑东药业有限公司 一种噻唑类化合物及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1249278B (de) 1962-06-09 1967-09-07 Monsanto Chemicals Limited Lon don Verfahren zur Kernarvlierung aromati scher oder heteroaromatischer Verbindungen
CN1003445B (zh) 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物,其制备方法和用途
DE4317320A1 (de) 1993-05-25 1994-12-01 Boehringer Mannheim Gmbh Neue Thiazolidindione und diese enthaltende Arzneimittel
US5475170A (en) 1994-06-27 1995-12-12 Albermarle Corporation Haloalkylation process
DE19711616A1 (de) 1997-03-20 1998-09-24 Boehringer Mannheim Gmbh Verbessertes Verfahren zur Herstellung von Thiazolidindionen
DE19711617A1 (de) 1997-03-20 1998-09-24 Boehringer Mannheim Gmbh Neue Thiazolidindione, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
ES2258431T3 (es) 1999-08-02 2006-09-01 F. Hoffmann-La Roche Ag Proceso para la preparacion de derivados de benzotiofeno.
DE10241042B4 (de) 2002-08-12 2006-04-13 Manfred Rennings Infobox

Also Published As

Publication number Publication date
CA2402374A1 (en) 2001-10-25
EP1282619A1 (en) 2003-02-12
ATE298336T1 (de) 2005-07-15
US6531609B2 (en) 2003-03-11
US20030092916A1 (en) 2003-05-15
CN1231482C (zh) 2005-12-14
US20010049445A1 (en) 2001-12-06
DE60111634T2 (de) 2006-05-18
MXPA02010022A (es) 2003-02-12
CN1422267A (zh) 2003-06-04
AU2001258306A1 (en) 2001-10-30
KR100519132B1 (ko) 2005-10-04
KR20020087136A (ko) 2002-11-21
US6753432B2 (en) 2004-06-22
US6620941B2 (en) 2003-09-16
WO2001079202A1 (en) 2001-10-25
JO2240B1 (en) 2004-10-07
EP1282619B1 (en) 2005-06-22
DE60111634D1 (de) 2005-07-28
JP2003531146A (ja) 2003-10-21
US20040024222A1 (en) 2004-02-05
ES2243493T3 (es) 2005-12-01

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