DE60111634D1 - Verfahren zur herstellung von thiazolidinedion-derivaten und zwischenprodukte - Google Patents

Verfahren zur herstellung von thiazolidinedion-derivaten und zwischenprodukte

Info

Publication number
DE60111634D1
DE60111634D1 DE60111634T DE60111634T DE60111634D1 DE 60111634 D1 DE60111634 D1 DE 60111634D1 DE 60111634 T DE60111634 T DE 60111634T DE 60111634 T DE60111634 T DE 60111634T DE 60111634 D1 DE60111634 D1 DE 60111634D1
Authority
DE
Germany
Prior art keywords
preparation
formula
thiazolidinedion
derivatives
intermediate products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60111634T
Other languages
English (en)
Other versions
DE60111634T2 (de
Inventor
Michelangelo Scalone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE60111634D1 publication Critical patent/DE60111634D1/de
Publication of DE60111634T2 publication Critical patent/DE60111634T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DE60111634T 2000-04-14 2001-04-04 Verfahren zur herstellung von thiazolidinedion-derivaten und zwischenprodukte Expired - Fee Related DE60111634T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00108303 2000-04-14
EP00108303 2000-04-14
PCT/EP2001/003802 WO2001079202A1 (en) 2000-04-14 2001-04-04 Processes for the preparation of thiazolidinedione derivatives and intermediates

Publications (2)

Publication Number Publication Date
DE60111634D1 true DE60111634D1 (de) 2005-07-28
DE60111634T2 DE60111634T2 (de) 2006-05-18

Family

ID=8168486

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60111634T Expired - Fee Related DE60111634T2 (de) 2000-04-14 2001-04-04 Verfahren zur herstellung von thiazolidinedion-derivaten und zwischenprodukte

Country Status (14)

Country Link
US (3) US6531609B2 (de)
EP (1) EP1282619B1 (de)
JP (1) JP2003531146A (de)
KR (1) KR100519132B1 (de)
CN (1) CN1231482C (de)
AT (1) ATE298336T1 (de)
AU (1) AU2001258306A1 (de)
CA (1) CA2402374A1 (de)
DE (1) DE60111634T2 (de)
DK (1) DK1282619T3 (de)
ES (1) ES2243493T3 (de)
JO (1) JO2240B1 (de)
MX (1) MXPA02010022A (de)
WO (1) WO2001079202A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004525168A (ja) 2001-04-06 2004-08-19 エフ.ホフマン−ラ ロシュ アーゲー 腫瘍の成長を抑制もしくは減少するための単独または他の治療薬との組合わせでのチアゾリジンジオン
US7361711B2 (en) * 2001-09-13 2008-04-22 Acushnet Company Compositions for use in golf balls
EP1641790A1 (de) * 2003-06-26 2006-04-05 F. Hoffmann-La Roche Ag Verfahren zur herstellung von insulinsenkenden mitteln und zwischenverbindungen
WO2005005423A1 (en) 2003-07-02 2005-01-20 F. Hoffmann-La Roche Ag Indolyl derivatives substituted with a thiazole ring and their use as ppar modulators
CN102746290B (zh) * 2012-06-21 2014-08-27 成都苑东药业有限公司 一种噻唑类化合物及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1249278B (de) 1962-06-09 1967-09-07 Monsanto Chemicals Limited Lon don Verfahren zur Kernarvlierung aromati scher oder heteroaromatischer Verbindungen
CN1003445B (zh) 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物,其制备方法和用途
DE4317320A1 (de) 1993-05-25 1994-12-01 Boehringer Mannheim Gmbh Neue Thiazolidindione und diese enthaltende Arzneimittel
US5475170A (en) 1994-06-27 1995-12-12 Albermarle Corporation Haloalkylation process
DE19711617A1 (de) 1997-03-20 1998-09-24 Boehringer Mannheim Gmbh Neue Thiazolidindione, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE19711616A1 (de) 1997-03-20 1998-09-24 Boehringer Mannheim Gmbh Verbessertes Verfahren zur Herstellung von Thiazolidindionen
DK1078923T3 (da) 1999-08-02 2006-07-10 Hoffmann La Roche Fremgangsmåde til fremstilling af benzothiophenderivater
DE10241042B4 (de) 2002-08-12 2006-04-13 Manfred Rennings Infobox

Also Published As

Publication number Publication date
US20040024222A1 (en) 2004-02-05
ATE298336T1 (de) 2005-07-15
CN1422267A (zh) 2003-06-04
KR20020087136A (ko) 2002-11-21
CA2402374A1 (en) 2001-10-25
US6753432B2 (en) 2004-06-22
JO2240B1 (en) 2004-10-07
DE60111634T2 (de) 2006-05-18
MXPA02010022A (es) 2003-02-12
US6620941B2 (en) 2003-09-16
US20010049445A1 (en) 2001-12-06
AU2001258306A1 (en) 2001-10-30
ES2243493T3 (es) 2005-12-01
JP2003531146A (ja) 2003-10-21
KR100519132B1 (ko) 2005-10-04
DK1282619T3 (da) 2005-10-17
CN1231482C (zh) 2005-12-14
US6531609B2 (en) 2003-03-11
US20030092916A1 (en) 2003-05-15
EP1282619A1 (de) 2003-02-12
WO2001079202A1 (en) 2001-10-25
EP1282619B1 (de) 2005-06-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee