DK0541594T3 - Cyklopentan-derivater, fremgangsmåde til fremstilling deraf samt farmaceutisk anvendelse af derivaterne - Google Patents

Cyklopentan-derivater, fremgangsmåde til fremstilling deraf samt farmaceutisk anvendelse af derivaterne

Info

Publication number
DK0541594T3
DK0541594T3 DK91912997.3T DK91912997T DK0541594T3 DK 0541594 T3 DK0541594 T3 DK 0541594T3 DK 91912997 T DK91912997 T DK 91912997T DK 0541594 T3 DK0541594 T3 DK 0541594T3
Authority
DK
Denmark
Prior art keywords
derivatives
pharmaceutical use
preparation
cyclopentane
formula
Prior art date
Application number
DK91912997.3T
Other languages
English (en)
Inventor
Ulrich Dr Klar
Hartmut Dr Rehwinkel
Helmut Prof Vorbrueggen
Karl-Heinz Dr Thierauch
Peter Dr Verhallen
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of DK0541594T3 publication Critical patent/DK0541594T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36Sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DK91912997.3T 1990-07-27 1991-07-22 Cyklopentan-derivater, fremgangsmåde til fremstilling deraf samt farmaceutisk anvendelse af derivaterne DK0541594T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4024347A DE4024347A1 (de) 1990-07-27 1990-07-27 Cyclopentanderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung

Publications (1)

Publication Number Publication Date
DK0541594T3 true DK0541594T3 (da) 1995-10-02

Family

ID=6411402

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91912997.3T DK0541594T3 (da) 1990-07-27 1991-07-22 Cyklopentan-derivater, fremgangsmåde til fremstilling deraf samt farmaceutisk anvendelse af derivaterne

Country Status (13)

Country Link
EP (1) EP0541594B1 (da)
JP (1) JPH06502390A (da)
AT (1) ATE122036T1 (da)
AU (1) AU8221291A (da)
CA (1) CA2088161A1 (da)
DE (3) DE4024347A1 (da)
DK (1) DK0541594T3 (da)
ES (1) ES2074721T3 (da)
IE (1) IE67507B1 (da)
IL (1) IL98970A0 (da)
PT (1) PT98464B (da)
WO (1) WO1992002495A1 (da)
ZA (1) ZA915905B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4036140A1 (de) * 1990-11-09 1992-05-14 Schering Ag 9-halogen-11ss-hydroxy-prostaglandinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
AU687906B2 (en) * 1993-12-15 1998-03-05 Alcon Laboratories, Inc. Use of certain prostaglandin analogues to treat glaucoma and ocular hypertension
SK3382000A3 (en) * 1997-09-09 2000-10-09 Procter & Gamble A compound having structure of aromatic substituted prostaglandins and its use for the treatment of bone disorders
TR200000671T2 (tr) * 1997-09-09 2000-07-21 The Procter & Gamble Company FP agonistleri olarak yararlı aromatik C16-C20-ikameli tetrahidro prostaglandinler.
SK3362000A3 (en) * 1997-09-09 2000-10-09 Procter & Gamble A compound analogous to prostaglandin f and use thereof
US6242493B1 (en) 1998-03-13 2001-06-05 Merck Frosst Canada & Co. Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment
WO1999047497A2 (en) * 1998-03-13 1999-09-23 Merck Frosst Canada & Co. Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment
NZ513825A (en) 1999-03-05 2001-09-28 Procter & Gamble C 16 unsaturated FP-selective prostaglandins analogs
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US7323591B2 (en) * 2006-01-10 2008-01-29 Allergan, Inc. Substituted cyclopentanes or cyclopentanones as therapeutic agents
WO2009140205A2 (en) * 2008-05-15 2009-11-19 Allergan, Inc. Therapeutic substituted cyclopentanes
CN102336754B (zh) * 2010-07-15 2017-04-12 浙江奥翔药业股份有限公司 恩替卡韦的合成方法及其中间体化合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1431561A (en) * 1973-01-31 1976-04-07 Ici Ltd Cyclopentane derivatives
IT1053781B (it) * 1974-09-25 1981-10-10 Erba C S P A Ora Farmitalia Omega nor cicloalcil 13.14 deidro prostaglandine
FR2349328A1 (fr) * 1976-04-30 1977-11-25 Roussel Uclaf Nouveaux derives de la 11-desoxy prostaglandine f2, leur procede de preparation et leur application comme medicaments
DE3126924A1 (de) * 1981-07-03 1983-01-20 Schering Ag, 1000 Berlin Und 4619 Bergkamen 9-fluor-prostaglandinderivate, verfahren zur herstellung und verwendung als arzneimittel
DE3325175A1 (de) * 1983-07-08 1985-01-17 Schering AG, 1000 Berlin und 4709 Bergkamen 11-halogen-prostanderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3510978A1 (de) * 1985-03-22 1986-09-25 Schering AG, Berlin und Bergkamen, 1000 Berlin Neue 9-halogenprostaglandine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
ES2054860T5 (es) * 1987-07-17 2003-11-01 Schering Ag Derivados de 9-halogeno-(z)-prostaglandinas, procedimiento para su preparacion y su utilizacion como medicamentos.
DE3923797A1 (de) * 1989-07-14 1991-01-24 Schering Ag 9-fluor-prostaglandin-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung

Also Published As

Publication number Publication date
EP0541594B1 (de) 1995-05-03
DE4191848D2 (de) 1993-10-07
IE912654A1 (en) 1992-01-29
IE67507B1 (en) 1996-04-03
IL98970A0 (en) 1992-07-15
CA2088161A1 (en) 1992-01-28
DE59105400D1 (de) 1995-06-08
ES2074721T3 (es) 1995-09-16
WO1992002495A1 (de) 1992-02-20
PT98464B (pt) 1997-10-31
ZA915905B (en) 1992-04-29
PT98464A (pt) 1992-05-29
AU8221291A (en) 1992-03-02
JPH06502390A (ja) 1994-03-17
ATE122036T1 (de) 1995-05-15
DE4024347A1 (de) 1992-01-30
EP0541594A1 (de) 1993-05-19

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