ES2097174T3 - Derivados de la 2-ciclohexan-1-il amina. - Google Patents
Derivados de la 2-ciclohexan-1-il amina.Info
- Publication number
- ES2097174T3 ES2097174T3 ES91117031T ES91117031T ES2097174T3 ES 2097174 T3 ES2097174 T3 ES 2097174T3 ES 91117031 T ES91117031 T ES 91117031T ES 91117031 T ES91117031 T ES 91117031T ES 2097174 T3 ES2097174 T3 ES 2097174T3
- Authority
- ES
- Spain
- Prior art keywords
- derivatives
- ciclohexan
- amina
- formula
- cyclohexan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/46—N-acyl derivatives
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C229/48—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/52—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/24—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/24—Esters of monothiocarboxylic acids having carbon atoms of esterified thiocarboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4021—Esters of aromatic acids (P-C aromatic linkage)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Abstract
LA PATENTE SE REFIERE A UN NUEVO DERIVADO 2-CICLOHEXANO-1-ILO-AMINO DE FORMULA (I) Y TRATA DE UN PROCEDIMIENTO PARA OBTENER UN COMPUESTO DE DICHA FORMULA, SU APLICACION COMO MEDIO ANTIMICROBIAL; TENIENDO A, R ELEVADO 1, R (AL CUADRADO) , R ELEVADO 3, UN SIGNIFICADO DESCRITO EN LA PATENTE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4033415A DE4033415A1 (de) | 1990-10-20 | 1990-10-20 | Antimikrobielle mittel sowie substituierte 2-cyclohexan-1-yl-amin-derivate und deren herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2097174T3 true ES2097174T3 (es) | 1997-04-01 |
Family
ID=6416725
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91117031T Expired - Lifetime ES2097174T3 (es) | 1990-10-20 | 1991-10-07 | Derivados de la 2-ciclohexan-1-il amina. |
Country Status (16)
Country | Link |
---|---|
US (2) | US5196441A (es) |
EP (1) | EP0482410B1 (es) |
JP (2) | JP3126183B2 (es) |
KR (1) | KR100219092B1 (es) |
AT (1) | ATE148610T1 (es) |
AU (1) | AU8599091A (es) |
BR (1) | BR9104533A (es) |
CA (1) | CA2053601A1 (es) |
CS (1) | CS314891A3 (es) |
DE (2) | DE4033415A1 (es) |
ES (1) | ES2097174T3 (es) |
IL (1) | IL99775A0 (es) |
PL (2) | PL292095A1 (es) |
PT (1) | PT99202A (es) |
TW (1) | TW210330B (es) |
ZA (1) | ZA918331B (es) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4134757A1 (de) * | 1991-10-22 | 1993-04-29 | Bayer Ag | Neue substituierte 2,3-dihydropyrane, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
GB9216441D0 (en) * | 1992-08-03 | 1992-09-16 | Ici Plc | Fungicidal process |
DE4338923C2 (de) * | 1993-11-15 | 1995-12-14 | Degussa | Verwendung von Kupfer-(II)-methioninat als Fungizid im Weinbau |
BR9607098B8 (pt) * | 1995-02-27 | 2014-11-18 | Gilead Sciences Inc | Composto e composição farmacêutica. |
US5866601A (en) * | 1995-02-27 | 1999-02-02 | Gilead Sciences, Inc. | Carbocyclic compounds |
US5763483A (en) * | 1995-12-29 | 1998-06-09 | Gilead Sciences, Inc. | Carbocyclic compounds |
US5859284A (en) * | 1996-08-23 | 1999-01-12 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
US6518438B2 (en) | 1996-08-23 | 2003-02-11 | Gilead Sciences, Inc. | Preparation of cyclohexene carboxylate derivatives |
US5994377A (en) * | 1996-10-21 | 1999-11-30 | Gilead Sciences, Inc. | Piperidine compounds |
US20040053999A1 (en) * | 1997-09-17 | 2004-03-18 | Bischofberger Norbert W. | Novel compounds and methods for synthesis and therapy |
TW477783B (en) * | 1997-12-12 | 2002-03-01 | Gilead Sciences Inc | Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same |
WO2003009815A2 (en) | 2001-07-25 | 2003-02-06 | Biomarin Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
ES2369473T3 (es) | 2004-10-07 | 2011-12-01 | Actamax Surgical Materials Llc | Adhesivo tisular polimérico basado en polisacárido para uso médico. |
CN101287411B (zh) | 2005-04-28 | 2013-03-06 | 普罗秋斯生物医学公司 | 药物信息系统及其用途 |
CN101594878A (zh) | 2006-09-18 | 2009-12-02 | 雷普特药品公司 | 通过给予受体相关蛋白(rap)-缀合物对肝病症的治疗 |
WO2008066787A2 (en) * | 2006-11-27 | 2008-06-05 | E. I. Du Pont De Nemours And Company | Multi-functional polyalkylene oxides, hydrogels and tissue adhesives |
US20090035249A1 (en) * | 2007-08-02 | 2009-02-05 | Bhatia Sujata K | Method of inhibiting proliferation of Escherichia coli |
WO2009064963A2 (en) * | 2007-11-14 | 2009-05-22 | E. I. Du Pont De Nemours And Company | Oxidized cationic polysaccharide-based polymer tissue adhesive for medical use |
US8551136B2 (en) | 2008-07-17 | 2013-10-08 | Actamax Surgical Materials, Llc | High swell, long-lived hydrogel sealant |
US20100015231A1 (en) * | 2008-07-17 | 2010-01-21 | E.I. Du Pont De Nemours And Company | Low swell, long-lived hydrogel sealant |
US8466327B2 (en) | 2008-11-19 | 2013-06-18 | Actamax Surgical Materials, Llc | Aldehyde-functionalized polyethers and method of making same |
US9044529B2 (en) * | 2008-11-19 | 2015-06-02 | Actamax Surgical Materials, Llc | Hydrogel tissue adhesive formed from aminated polysaccharide and aldehyde-functionalized multi-arm polyether |
US20100160960A1 (en) * | 2008-12-19 | 2010-06-24 | E. I. Du Pont De Nemours And Company | Hydrogel tissue adhesive having increased degradation time |
NZ594310A (en) | 2009-02-20 | 2014-02-28 | To Bbb Holding B V | Glutathione-based drug delivery system |
US8951989B2 (en) | 2009-04-09 | 2015-02-10 | Actamax Surgical Materials, Llc | Hydrogel tissue adhesive having reduced degradation time |
KR20180114970A (ko) | 2009-05-06 | 2018-10-19 | 라보라토리 스킨 케어, 인크. | 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법 |
US8580950B2 (en) | 2009-07-02 | 2013-11-12 | Actamax Surgical Materials, Llc | Aldehyde-functionalized polysaccharides |
EP2448604B1 (en) | 2009-07-02 | 2016-03-23 | Actamax Surgical Materials LLC | Hydrogel tissue adhesive for medical use |
WO2011002956A1 (en) | 2009-07-02 | 2011-01-06 | E. I. Du Pont De Nemours And Company | Aldehyde-functionalized polysaccharides |
US8796242B2 (en) | 2009-07-02 | 2014-08-05 | Actamax Surgical Materials, Llc | Hydrogel tissue adhesive for medical use |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
US8859705B2 (en) | 2012-11-19 | 2014-10-14 | Actamax Surgical Materials Llc | Hydrogel tissue adhesive having decreased gelation time and decreased degradation time |
EP3027659B1 (en) | 2013-07-29 | 2020-12-09 | Actamax Surgical Materials LLC | Low swell tissue adhesive and sealant formulations |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR820736A (fr) * | 1936-07-23 | 1937-11-17 | Cie Nat Matieres Colorantes | Nouvelles amines aromatiques, colorants obtenus à l'aide de ces amines, procédé pour la préparation de ces produits |
US3510492A (en) * | 1968-05-13 | 1970-05-05 | Upjohn Co | 2-anilino and 2-anilinomethyl cycloalkylamines |
DE1935458A1 (de) * | 1969-07-12 | 1971-01-14 | Cassella Farbwerke Mainkur Ag | Basisch substituierte Cyclohexyl- und Norbornyl-ketone |
HU177576B (en) * | 1975-06-02 | 1981-11-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing 2-amino-cyclohexane carboxylic acid,its amides and similar compounds |
US4554017A (en) * | 1978-06-03 | 1985-11-19 | Bayer Aktiengesellschaft | Method and compositions for regulating plant growth using cycloalkane-carboxylic acid compounds |
US4673631A (en) * | 1984-12-15 | 1987-06-16 | Canon Kabushiki Kaisha | Toner, charge-imparting material and composition containing metal complex |
US4554277A (en) * | 1985-02-25 | 1985-11-19 | Stauffer Chemical Co. | Pyridylpropyl cyclohexene carboxylates as insect repellents |
EP0376072B1 (de) * | 1988-12-27 | 1994-02-16 | Bayer Ag | Fungizide und herbizide Mittel sowie substituierte 2-Cyclohexen-1-yl-amin-Derivate und deren Herstellung |
-
1990
- 1990-10-20 DE DE4033415A patent/DE4033415A1/de not_active Withdrawn
-
1991
- 1991-09-19 TW TW080107415A patent/TW210330B/zh active
- 1991-10-07 ES ES91117031T patent/ES2097174T3/es not_active Expired - Lifetime
- 1991-10-07 EP EP91117031A patent/EP0482410B1/de not_active Expired - Lifetime
- 1991-10-07 DE DE59108530T patent/DE59108530D1/de not_active Expired - Fee Related
- 1991-10-07 AT AT91117031T patent/ATE148610T1/de not_active IP Right Cessation
- 1991-10-10 PT PT99202A patent/PT99202A/pt not_active Application Discontinuation
- 1991-10-10 US US07/777,832 patent/US5196441A/en not_active Expired - Fee Related
- 1991-10-15 JP JP03293771A patent/JP3126183B2/ja not_active Expired - Fee Related
- 1991-10-17 CS CS913148A patent/CS314891A3/cs unknown
- 1991-10-17 CA CA002053601A patent/CA2053601A1/en not_active Abandoned
- 1991-10-17 IL IL99775A patent/IL99775A0/xx unknown
- 1991-10-17 KR KR1019910018277A patent/KR100219092B1/ko not_active IP Right Cessation
- 1991-10-18 PL PL29209591A patent/PL292095A1/xx unknown
- 1991-10-18 PL PL29503091A patent/PL295030A1/xx unknown
- 1991-10-18 BR BR919104533A patent/BR9104533A/pt not_active Application Discontinuation
- 1991-10-18 ZA ZA918331A patent/ZA918331B/xx unknown
- 1991-10-18 AU AU85990/91A patent/AU8599091A/en not_active Abandoned
-
1992
- 1992-10-05 US US07/956,535 patent/US5428073A/en not_active Expired - Fee Related
-
1999
- 1999-08-20 JP JP11234146A patent/JP2000080003A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP3126183B2 (ja) | 2001-01-22 |
PL295030A1 (en) | 1993-05-31 |
IL99775A0 (en) | 1992-08-18 |
AU8599091A (en) | 1992-04-30 |
CA2053601A1 (en) | 1992-04-21 |
PT99202A (pt) | 1992-09-30 |
ATE148610T1 (de) | 1997-02-15 |
EP0482410B1 (de) | 1997-02-05 |
EP0482410A3 (en) | 1992-09-09 |
JPH04360858A (ja) | 1992-12-14 |
DE59108530D1 (de) | 1997-03-20 |
ZA918331B (en) | 1992-07-29 |
KR920007539A (ko) | 1992-05-27 |
PL292095A1 (en) | 1992-11-02 |
EP0482410A2 (de) | 1992-04-29 |
TW210330B (es) | 1993-08-01 |
JP2000080003A (ja) | 2000-03-21 |
BR9104533A (pt) | 1992-06-09 |
US5196441A (en) | 1993-03-23 |
DE4033415A1 (de) | 1992-04-23 |
US5428073A (en) | 1995-06-27 |
KR100219092B1 (ko) | 1999-10-01 |
CS314891A3 (en) | 1992-05-13 |
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Legal Events
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