DK1227814T3 - Hormonal sammensætning baseret på nomegestrolacetat og et östrogen samt anvendelse heraf - Google Patents
Hormonal sammensætning baseret på nomegestrolacetat og et östrogen samt anvendelse herafInfo
- Publication number
- DK1227814T3 DK1227814T3 DK00971476T DK00971476T DK1227814T3 DK 1227814 T3 DK1227814 T3 DK 1227814T3 DK 00971476 T DK00971476 T DK 00971476T DK 00971476 T DK00971476 T DK 00971476T DK 1227814 T3 DK1227814 T3 DK 1227814T3
- Authority
- DK
- Denmark
- Prior art keywords
- estrogen
- well
- composition based
- nomegestrol acetate
- hormonal composition
- Prior art date
Links
- 229940011871 estrogen Drugs 0.000 title 1
- 239000000262 estrogen Substances 0.000 title 1
- 230000003054 hormonal effect Effects 0.000 title 1
- 229960004190 nomegestrol acetate Drugs 0.000 title 1
- IIVBFTNIGYRNQY-YQLZSBIMSA-N nomegestrol acetate Chemical compound C1=C(C)C2=CC(=O)CC[C@@H]2[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(C)=O)(OC(=O)C)[C@@]1(C)CC2 IIVBFTNIGYRNQY-YQLZSBIMSA-N 0.000 title 1
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 206010030247 Oestrogen deficiency Diseases 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 229960005309 estradiol Drugs 0.000 abstract 1
- KZUIYQJTUIACIG-YBZCJVABSA-N nomegestrol Chemical compound C1=C(C)C2=CC(=O)CC[C@@H]2[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)C)(O)[C@@]1(C)CC2 KZUIYQJTUIACIG-YBZCJVABSA-N 0.000 abstract 1
- 229960004911 nomegestrol Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Reproductive Health (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/FR1999/002588 WO2001030356A1 (fr) | 1999-10-25 | 1999-10-25 | Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation |
| PCT/FR2000/002939 WO2001030357A1 (fr) | 1999-10-25 | 2000-10-24 | Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1227814T3 true DK1227814T3 (da) | 2005-04-11 |
Family
ID=9542727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00971476T DK1227814T3 (da) | 1999-10-25 | 2000-10-24 | Hormonal sammensætning baseret på nomegestrolacetat og et östrogen samt anvendelse heraf |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US8168619B1 (cs) |
| EP (1) | EP1227814B1 (cs) |
| JP (1) | JP5036943B2 (cs) |
| KR (1) | KR100623788B1 (cs) |
| CN (1) | CN100553637C (cs) |
| AP (1) | AP1625A (cs) |
| AT (1) | ATE286400T1 (cs) |
| AU (1) | AU777704B2 (cs) |
| BR (1) | BRPI0014979B8 (cs) |
| CA (1) | CA2389025C (cs) |
| CZ (1) | CZ303248B6 (cs) |
| DE (1) | DE60017281T2 (cs) |
| DK (1) | DK1227814T3 (cs) |
| ES (1) | ES2235967T3 (cs) |
| HK (1) | HK1050472B (cs) |
| HU (1) | HU229382B1 (cs) |
| IL (2) | IL148953A0 (cs) |
| MX (1) | MXPA02004084A (cs) |
| NO (1) | NO327973B1 (cs) |
| NZ (1) | NZ518145A (cs) |
| OA (1) | OA12072A (cs) |
| PL (1) | PL199848B1 (cs) |
| PT (1) | PT1227814E (cs) |
| RU (1) | RU2261106C2 (cs) |
| SI (1) | SI1227814T1 (cs) |
| WO (2) | WO2001030356A1 (cs) |
| ZA (1) | ZA200203398B (cs) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2754179B1 (fr) | 1996-10-08 | 1998-12-24 | Theramex | Nouvelle composition hormononale et son utilisation |
| WO2001030356A1 (fr) | 1999-10-25 | 2001-05-03 | Laboratoire Theramex | Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation |
| FR2814074B1 (fr) * | 2000-09-15 | 2003-03-07 | Theramex | Nouvelles compositions estro-progestatives topiques a effet systemique |
| CA2447178C (en) | 2001-05-18 | 2010-06-08 | Christian Franz Holinka | Pharmaceutical composition for use in hormone replacement therapy |
| PT1390042E (pt) | 2001-05-23 | 2008-03-10 | Pantarhei Bioscience Bv | Sistema de administração de um medicamento que compreende estrogénio tetrahidroxilado destinado à contracepção hormonal |
| EP1390041B1 (en) | 2001-05-23 | 2009-11-25 | Pantarhei Bioscience B.V. | Drug delivery system comprising a tetrahydroxylated estrogen for use in hormonal contraception |
| US8026228B2 (en) | 2001-11-15 | 2011-09-27 | Pantarhei Bioscience B.V. | Estrogenic compounds in combination with progestogenic compounds in hormone-replacement therapy |
| ES2399423T3 (es) | 2002-06-11 | 2013-04-01 | Pantarhei Bioscience B.V. | Método para tratar la piel humana y una composición para el cuidado de la piel para su uso en tal método |
| EP1511496B1 (en) | 2002-06-11 | 2006-09-27 | Pantarhei Bioscience B.V. | Method of treating or preventing immune mediated disorders and pharmaceutical formulation for use therein |
| RU2005101638A (ru) * | 2002-06-25 | 2006-01-20 | Уайт (Us) | Использование циклокарбаматных производных для лечения гормонзависимых состояний |
| DE60318447T2 (de) | 2002-07-12 | 2009-01-02 | Pantarhei Bioscience B.V. | Pharmazeutische zusammensetzung enthaltend estetrolderivate und anwendung in der krebsbehandlung |
| DE60318092T2 (de) | 2002-10-23 | 2008-11-27 | Pantarhei Bioscience B.V. | Pharmazeutische zusammensetzung enthaltend estetrolderivate und anwendung in der krebsbehandlung |
| DE602008001783D1 (de) | 2007-01-08 | 2010-08-26 | Pantarhei Bioscience Bv | Verfahren zur behandlung oder prävention von unfruchtbarkeit bei weiblichen säugern und pharmazeutisches kit zur anwendung dieses verfahrens |
| CN107007611B (zh) * | 2017-06-02 | 2020-04-14 | 上海市计划生育科学研究所 | 醋酸诺美孕酮在制备治疗子宫内膜癌的药物中的应用 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4826831A (en) * | 1983-08-05 | 1989-05-02 | Pre Jay Holdings Limited | Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens |
| JPS61243059A (ja) | 1985-04-19 | 1986-10-29 | Konishi Kagaku Kogyo Kk | 高純度４，４′−ジヒドロキシジフエニルスルホンの製造法 |
| DE3603644A1 (de) | 1986-02-06 | 1987-08-13 | Metabowerke Kg | Spannfutter zum einspannen von bohrern oder schlagbohrern |
| US5208225A (en) * | 1986-02-27 | 1993-05-04 | Warner-Lambert Company | Compositions containing fixed combinations |
| ZA87332B (en) | 1986-02-27 | 1987-08-26 | Warner Lambert Co | Compositions containing fixed combinations |
| US5256421A (en) | 1987-09-24 | 1993-10-26 | Jencap Research Ltd. | Hormone preparation and method |
| US5108995A (en) | 1987-09-24 | 1992-04-28 | Jencap Research Ltd. | Hormone preparation and method |
| CA1332227C (en) | 1987-09-24 | 1994-10-04 | Robert F. Casper | Oral contraceptive formulation |
| US5276022A (en) | 1987-09-24 | 1994-01-04 | Jencap Research Ltd. | Hormone preparation and method |
| HU214598B (hu) | 1987-09-24 | 1998-04-28 | Jencap Research Ltd | Eljárás fogamzásgátló és hormonterápiához alkalmazható, ösztrogént és progesztint tartalmazó gyógyszerkészítmények előállítására |
| HUT52382A (en) | 1988-03-14 | 1990-07-28 | Sandoz Ag | Process for producing pharmaceutical compositions comprising as active ingredient unsubstituted progestin in 19-position and estrogen in the given case |
| IE71203B1 (en) | 1990-12-13 | 1997-02-12 | Akzo Nv | Low estrogen oral contraceptives |
| FR2695826B1 (fr) | 1992-09-21 | 1995-01-06 | Theramex | Nouvelles compositions pharmaceutiques à base de dérivés de nomégestrol et leurs procédés d'obtention. |
| US5554601A (en) | 1993-11-05 | 1996-09-10 | University Of Florida | Methods for neuroprotection |
| US5552394A (en) | 1994-07-22 | 1996-09-03 | The Medical College Of Hampton Roads | Low dose oral contraceptives with less breakthrough bleeding and sustained efficacy |
| US6613757B1 (en) | 1994-09-22 | 2003-09-02 | Board Of Regents, The University Of Texas System | Combination of prostacyclin with an estrogen or progestin for the prevention and treatment of atherosclerotic vascular disease including preeclampsia and for the treatment of hypertension, and for hormone replacement therapy |
| SE9403389D0 (sv) | 1994-10-06 | 1994-10-06 | Astra Ab | Pharmaceutical composition containing derivattves of sex hormones |
| FR2737411B1 (fr) | 1995-08-01 | 1997-10-17 | Theramex | Nouveaux medicaments hormonaux et leur utilisation pour la correction des carences estrogeniques |
| US6096720A (en) | 1995-08-01 | 2000-08-01 | Novartis Ag | Liposomal oligonucleotide compositions |
| US5888543A (en) | 1996-07-26 | 1999-03-30 | American Home Products Corporation | Oral contraceptives |
| FR2754179B1 (fr) | 1996-10-08 | 1998-12-24 | Theramex | Nouvelle composition hormononale et son utilisation |
| WO2001030355A1 (fr) | 1999-10-25 | 2001-05-03 | Laboratoire Theramex | Medicament contraceptif a base d'un progestatif et d'un estrogene et son mode de preparation |
| DE19739916C2 (de) | 1997-09-11 | 2001-09-13 | Hesch Rolf Dieter | Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen |
| FR2776191B1 (fr) * | 1998-03-23 | 2002-05-31 | Theramex | Composition hormonale topique a effet systemique |
| WO2001030356A1 (fr) | 1999-10-25 | 2001-05-03 | Laboratoire Theramex | Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation |
| FR2814074B1 (fr) * | 2000-09-15 | 2003-03-07 | Theramex | Nouvelles compositions estro-progestatives topiques a effet systemique |
| CA2467237C (en) * | 2001-11-15 | 2011-09-20 | Herman Jan Tijmen Coelingh Bennink | Method of preventing or treating benign gynaecological disorders |
| PE20081895A1 (es) | 2007-03-26 | 2009-01-26 | Theramex | Regimen anticonceptivo oral |
-
1999
- 1999-10-25 WO PCT/FR1999/002588 patent/WO2001030356A1/fr not_active Ceased
- 1999-10-29 US US09/423,109 patent/US8168619B1/en not_active Expired - Fee Related
-
2000
- 2000-10-24 OA OA1200200119A patent/OA12072A/fr unknown
- 2000-10-24 NZ NZ518145A patent/NZ518145A/en not_active IP Right Cessation
- 2000-10-24 KR KR1020027005259A patent/KR100623788B1/ko not_active Expired - Fee Related
- 2000-10-24 PT PT00971476T patent/PT1227814E/pt unknown
- 2000-10-24 CA CA002389025A patent/CA2389025C/fr not_active Expired - Lifetime
- 2000-10-24 CN CNB008147841A patent/CN100553637C/zh not_active Expired - Fee Related
- 2000-10-24 AT AT00971476T patent/ATE286400T1/de active
- 2000-10-24 EP EP00971476A patent/EP1227814B1/fr not_active Expired - Lifetime
- 2000-10-24 RU RU2002113652/15A patent/RU2261106C2/ru not_active IP Right Cessation
- 2000-10-24 HK HK03100875.7A patent/HK1050472B/zh not_active IP Right Cessation
- 2000-10-24 DE DE60017281T patent/DE60017281T2/de not_active Expired - Lifetime
- 2000-10-24 CZ CZ20021427A patent/CZ303248B6/cs not_active IP Right Cessation
- 2000-10-24 HU HU0203721A patent/HU229382B1/hu not_active IP Right Cessation
- 2000-10-24 DK DK00971476T patent/DK1227814T3/da active
- 2000-10-24 WO PCT/FR2000/002939 patent/WO2001030357A1/fr not_active Ceased
- 2000-10-24 AU AU10326/01A patent/AU777704B2/en not_active Ceased
- 2000-10-24 MX MXPA02004084A patent/MXPA02004084A/es active IP Right Grant
- 2000-10-24 BR BRPI0014979A patent/BRPI0014979B8/pt not_active IP Right Cessation
- 2000-10-24 AP APAP/P/2002/002475A patent/AP1625A/en active
- 2000-10-24 ES ES00971476T patent/ES2235967T3/es not_active Expired - Lifetime
- 2000-10-24 PL PL356847A patent/PL199848B1/pl unknown
- 2000-10-24 JP JP2001532775A patent/JP5036943B2/ja not_active Expired - Fee Related
- 2000-10-24 SI SI200030615T patent/SI1227814T1/xx unknown
- 2000-10-24 IL IL14895300A patent/IL148953A0/xx active IP Right Grant
-
2002
- 2002-04-01 IL IL148953A patent/IL148953A/en unknown
- 2002-04-25 NO NO20021949A patent/NO327973B1/no not_active IP Right Cessation
- 2002-04-29 ZA ZA200203398A patent/ZA200203398B/en unknown
-
2012
- 2012-04-17 US US13/448,953 patent/US9084796B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1227814T3 (da) | Hormonal sammensætning baseret på nomegestrolacetat og et östrogen samt anvendelse heraf | |
| EA200201000A1 (ru) | Гормон-заместительная терапия | |
| AR073972A2 (es) | Composiciones farmaceuticas para el tratamiento de carencias estrogenicas en la menopausia y para la prevencion de la osteoporosis en mujeres menopausicas | |
| NO975586D0 (no) | Transdermal innretning og fremgangsmåte for administrering av 17-deacetyl norgestimat alene eller i kombinasjon med et östrogen | |
| AR024566A1 (es) | Administracion de esteroides androgenicos no orales a mujeres | |
| SE9704870D0 (sv) | New pharmaceutical formulation I | |
| CR7420A (es) | Composiciones farmaceuticas que comprenden uno o varios esteroides, uno o varios componentes de tetrahiidrofolatos y vitamina b12 | |
| NO993979L (no) | FremgangsmÕte for Õ forhindre og forsinke starten pÕ Alzheimer's sykdom og sammensetning derfor | |
| IL124459A0 (en) | Antagonists of gonadotropin releasing hormone | |
| MX9804850A (es) | Antagonistas de hormona liberadora de gonadotropina. | |
| KR960700727A (ko) | 호르몬 대체 치료(hormone replacement therapy) | |
| NZ512099A (en) | Use of hydroxymatairesinol in cancer prevention | |
| BR9509155A (pt) | Apilcação de inibidores de aromatase para preparação de um medicamento para tratamento de uma deficiência relativa de andrôgeno no homem | |
| AU7371600A (en) | Use of alpha-linolenic acid metabolites for treatment or prevention of cancer | |
| MXPA03001859A (es) | Metodo para incrementar en la mujer testosterona y concentraciones de esteroides relacionados. | |
| EA200301022A1 (ru) | Гормональная заместительная терапия | |
| TR200103710T2 (tr) | Vajinal mukozayı etkileyen patolojilerin topikal tedavisinde kullanıma yönelik E vitamini | |
| NZ522242A (en) | Use of 13-hode as a regulator of vascular biocompatibility and an inhibitor of cell hyperplasia | |
| MX2007013137A (es) | Regimen anticonceptivo con dosificacion de estrogeno ampliada. | |
| DE69519933D1 (de) | Prostaglandinanaloga zur oralen oder vaginalen verabreichung in der routinebehandlung des dritten stadiums der geburtswehen | |
| CO4960657A1 (es) | Composicion farmaceutica | |
| AR049196A1 (es) | Anticonceptivo hormonal conteniendo una combinacion de etinilestradiol y acetato de clormadinona | |
| AU6567800A (en) | Substances and agents for positively influencing collagen | |
| AR039477A1 (es) | Terapia de reemplazo hormonal | |
| DE59404903D1 (de) | Oral estrogen wirksame ester des 14 alpha,15 alpha-methylen-estradiols |