SI1227814T1 - Hormonal composition based on nomegestrol acetate and an oestrogen and use thereof - Google Patents

Hormonal composition based on nomegestrol acetate and an oestrogen and use thereof

Info

Publication number
SI1227814T1
SI1227814T1 SI200030615T SI200030615T SI1227814T1 SI 1227814 T1 SI1227814 T1 SI 1227814T1 SI 200030615 T SI200030615 T SI 200030615T SI 200030615 T SI200030615 T SI 200030615T SI 1227814 T1 SI1227814 T1 SI 1227814T1
Authority
SI
Slovenia
Prior art keywords
oestrogen
composition based
nomegestrol acetate
hormonal composition
hormonal
Prior art date
Application number
SI200030615T
Other languages
English (en)
Slovenian (sl)
Inventor
Jacques Le Clos De Cimiez Paris
Jean-Louis Thomas
Original Assignee
Laboratoire Theramex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Theramex filed Critical Laboratoire Theramex
Publication of SI1227814T1 publication Critical patent/SI1227814T1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
SI200030615T 1999-10-25 2000-10-24 Hormonal composition based on nomegestrol acetate and an oestrogen and use thereof SI1227814T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/FR1999/002588 WO2001030356A1 (fr) 1999-10-25 1999-10-25 Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation
PCT/FR2000/002939 WO2001030357A1 (fr) 1999-10-25 2000-10-24 Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation

Publications (1)

Publication Number Publication Date
SI1227814T1 true SI1227814T1 (en) 2005-06-30

Family

ID=9542727

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200030615T SI1227814T1 (en) 1999-10-25 2000-10-24 Hormonal composition based on nomegestrol acetate and an oestrogen and use thereof

Country Status (27)

Country Link
US (2) US8168619B1 (cs)
EP (1) EP1227814B1 (cs)
JP (1) JP5036943B2 (cs)
KR (1) KR100623788B1 (cs)
CN (1) CN100553637C (cs)
AP (1) AP1625A (cs)
AT (1) ATE286400T1 (cs)
AU (1) AU777704B2 (cs)
BR (1) BRPI0014979B8 (cs)
CA (1) CA2389025C (cs)
CZ (1) CZ303248B6 (cs)
DE (1) DE60017281T2 (cs)
DK (1) DK1227814T3 (cs)
ES (1) ES2235967T3 (cs)
HK (1) HK1050472B (cs)
HU (1) HU229382B1 (cs)
IL (2) IL148953A0 (cs)
MX (1) MXPA02004084A (cs)
NO (1) NO327973B1 (cs)
NZ (1) NZ518145A (cs)
OA (1) OA12072A (cs)
PL (1) PL199848B1 (cs)
PT (1) PT1227814E (cs)
RU (1) RU2261106C2 (cs)
SI (1) SI1227814T1 (cs)
WO (2) WO2001030356A1 (cs)
ZA (1) ZA200203398B (cs)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2754179B1 (fr) 1996-10-08 1998-12-24 Theramex Nouvelle composition hormononale et son utilisation
WO2001030356A1 (fr) 1999-10-25 2001-05-03 Laboratoire Theramex Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation
FR2814074B1 (fr) * 2000-09-15 2003-03-07 Theramex Nouvelles compositions estro-progestatives topiques a effet systemique
US8048869B2 (en) 2001-05-18 2011-11-01 Pantarhei Bioscience B.V. Pharmaceutical composition for use in hormone replacement therapy
ES2296943T3 (es) 2001-05-23 2008-05-01 Pantarhei Bioscience B.V. Sistema de administracion de un medicamento estrogeno tetrahidroxilado destinado a la contracepcion hormonal.
CA2448273C (en) 2001-05-23 2010-06-29 Christian Franz Holinka Drug delivery system comprising a tetrahydroxylated estrogen for use in hormonal contraception
ATE347365T1 (de) * 2001-11-15 2006-12-15 Pantarhei Bioscience Bv Verwendung von öestrogen in kombination mit progestogen für die hormonsubstitutions-therapie
SI1511496T1 (sl) 2002-06-11 2007-04-30 Pantarhei Bioscience Bv Metoda zdravljenja ali prevencije imunsko mediiranih motenj in farmacevtska formulacija za njeno uporabo
US7943604B2 (en) 2002-06-11 2011-05-17 Pantarhei Bioscience B.V. Method of treating human skin and a skin care composition for use in such a method
JP2005535624A (ja) * 2002-06-25 2005-11-24 ワイス ホルモン関連症状の治療におけるシクロチオカルバメート誘導体の使用
PT1526856E (pt) 2002-07-12 2008-04-11 Pantarhei Bioscience Bv Composição farmacêutica que compreende derivados do estretol para ser utilizada no tratamento do cancro
DK1556058T3 (da) 2002-10-23 2008-03-03 Pantarhei Bioscience Bv Farmaceutiske præparater omfattende östetrolderivater til anvendelse i cancerterapi
CA2674325A1 (en) 2007-01-08 2008-07-17 Pantarhei Bioscience B.V. Method of treating or preventing infertility in a female mammal and pharmaceutical kit for use in such method
CN107007611B (zh) * 2017-06-02 2020-04-14 上海市计划生育科学研究所 醋酸诺美孕酮在制备治疗子宫内膜癌的药物中的应用

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826831A (en) * 1983-08-05 1989-05-02 Pre Jay Holdings Limited Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens
JPS61243059A (ja) 1985-04-19 1986-10-29 Konishi Kagaku Kogyo Kk 高純度４，４′−ジヒドロキシジフエニルスルホンの製造法
DE3603644A1 (de) 1986-02-06 1987-08-13 Metabowerke Kg Spannfutter zum einspannen von bohrern oder schlagbohrern
ZA87332B (en) 1986-02-27 1987-08-26 Warner Lambert Co Compositions containing fixed combinations
US5208225A (en) * 1986-02-27 1993-05-04 Warner-Lambert Company Compositions containing fixed combinations
US5256421A (en) 1987-09-24 1993-10-26 Jencap Research Ltd. Hormone preparation and method
CA1332227C (en) 1987-09-24 1994-10-04 Robert F. Casper Oral contraceptive formulation
ATE209919T1 (de) 1987-09-24 2001-12-15 Jencap Res Ltd Oestrogen und progestin enthaltende verhütungspackungen
US5276022A (en) 1987-09-24 1994-01-04 Jencap Research Ltd. Hormone preparation and method
US5108995A (en) 1987-09-24 1992-04-28 Jencap Research Ltd. Hormone preparation and method
HUT52382A (en) 1988-03-14 1990-07-28 Sandoz Ag Process for producing pharmaceutical compositions comprising as active ingredient unsubstituted progestin in 19-position and estrogen in the given case
IE71203B1 (en) 1990-12-13 1997-02-12 Akzo Nv Low estrogen oral contraceptives
FR2695826B1 (fr) 1992-09-21 1995-01-06 Theramex Nouvelles compositions pharmaceutiques à base de dérivés de nomégestrol et leurs procédés d'obtention.
US5554601A (en) 1993-11-05 1996-09-10 University Of Florida Methods for neuroprotection
US5552394A (en) 1994-07-22 1996-09-03 The Medical College Of Hampton Roads Low dose oral contraceptives with less breakthrough bleeding and sustained efficacy
US6613757B1 (en) 1994-09-22 2003-09-02 Board Of Regents, The University Of Texas System Combination of prostacyclin with an estrogen or progestin for the prevention and treatment of atherosclerotic vascular disease including preeclampsia and for the treatment of hypertension, and for hormone replacement therapy
SE9403389D0 (sv) 1994-10-06 1994-10-06 Astra Ab Pharmaceutical composition containing derivattves of sex hormones
AU705644B2 (en) 1995-08-01 1999-05-27 Novartis Ag Liposomal oligonucleotide compositions
FR2737411B1 (fr) 1995-08-01 1997-10-17 Theramex Nouveaux medicaments hormonaux et leur utilisation pour la correction des carences estrogeniques
US5888543A (en) 1996-07-26 1999-03-30 American Home Products Corporation Oral contraceptives
FR2754179B1 (fr) 1996-10-08 1998-12-24 Theramex Nouvelle composition hormononale et son utilisation
WO2001030355A1 (fr) 1999-10-25 2001-05-03 Laboratoire Theramex Medicament contraceptif a base d'un progestatif et d'un estrogene et son mode de preparation
DE19739916C2 (de) 1997-09-11 2001-09-13 Hesch Rolf Dieter Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen
FR2776191B1 (fr) * 1998-03-23 2002-05-31 Theramex Composition hormonale topique a effet systemique
WO2001030356A1 (fr) 1999-10-25 2001-05-03 Laboratoire Theramex Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation
FR2814074B1 (fr) * 2000-09-15 2003-03-07 Theramex Nouvelles compositions estro-progestatives topiques a effet systemique
EP1443966B1 (en) * 2001-11-15 2007-03-14 Pantarhei Bioscience B.V. Method of preventing or treating benign gynaecological disorders
US20080242650A1 (en) 2007-03-26 2008-10-02 Jean-Louis Thomas Oral contraceptive regimen

Also Published As

Publication number Publication date
CN100553637C (zh) 2009-10-28
NZ518145A (en) 2005-01-28
JP2003515531A (ja) 2003-05-07
HK1050472A1 (en) 2003-06-27
CZ303248B6 (cs) 2012-06-20
CA2389025C (fr) 2009-12-08
BRPI0014979B1 (pt) 2016-08-02
RU2002113652A (ru) 2004-03-27
NO327973B1 (no) 2009-11-02
PL356847A1 (en) 2004-07-12
PL199848B1 (pl) 2008-11-28
DE60017281D1 (de) 2005-02-10
DK1227814T3 (da) 2005-04-11
AU1032601A (en) 2001-05-08
ZA200203398B (en) 2003-12-03
HUP0203721A2 (hu) 2003-03-28
KR20020057979A (ko) 2002-07-12
BRPI0014979B8 (pt) 2021-05-25
EP1227814A1 (fr) 2002-08-07
IL148953A0 (en) 2002-11-10
ES2235967T3 (es) 2005-07-16
HU229382B1 (hu) 2013-11-28
CZ20021427A3 (cs) 2002-08-14
AU777704B2 (en) 2004-10-28
PT1227814E (pt) 2005-05-31
US9084796B2 (en) 2015-07-21
AP1625A (en) 2006-07-04
WO2001030357A1 (fr) 2001-05-03
BR0014979A (pt) 2002-11-26
AP2002002475A0 (en) 2002-06-30
WO2001030356A1 (fr) 2001-05-03
NO20021949L (no) 2002-04-25
JP5036943B2 (ja) 2012-09-26
RU2261106C2 (ru) 2005-09-27
CA2389025A1 (fr) 2001-05-03
DE60017281T2 (de) 2005-12-08
ATE286400T1 (de) 2005-01-15
EP1227814B1 (fr) 2005-01-05
HK1050472B (zh) 2005-07-08
KR100623788B1 (ko) 2006-09-18
US8168619B1 (en) 2012-05-01
US20130172300A1 (en) 2013-07-04
HUP0203721A3 (en) 2003-07-28
IL148953A (en) 2007-06-03
CN1382053A (zh) 2002-11-27
NO20021949D0 (no) 2002-04-25
MXPA02004084A (es) 2003-08-20
OA12072A (fr) 2006-05-04

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