HK1050472B - 基於醋酸諾美孕酮和雌激素的激素組合物及其用途 - Google Patents

基於醋酸諾美孕酮和雌激素的激素組合物及其用途

Info

Publication number
HK1050472B
HK1050472B HK03100875.7A HK03100875A HK1050472B HK 1050472 B HK1050472 B HK 1050472B HK 03100875 A HK03100875 A HK 03100875A HK 1050472 B HK1050472 B HK 1050472B
Authority
HK
Hong Kong
Prior art keywords
oestrogen
composition based
nomegestrol acetate
hormonal composition
hormonal
Prior art date
Application number
HK03100875.7A
Other languages
English (en)
Other versions
HK1050472A1 (en
Inventor
Paris Jacques
Thomas Jean-Louis
Original Assignee
Laboratoire Theramex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Theramex filed Critical Laboratoire Theramex
Publication of HK1050472A1 publication Critical patent/HK1050472A1/xx
Publication of HK1050472B publication Critical patent/HK1050472B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
HK03100875.7A 1999-10-25 2003-02-06 基於醋酸諾美孕酮和雌激素的激素組合物及其用途 HK1050472B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/FR1999/002588 WO2001030356A1 (fr) 1999-10-25 1999-10-25 Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation
PCT/FR2000/002939 WO2001030357A1 (fr) 1999-10-25 2000-10-24 Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation

Publications (2)

Publication Number Publication Date
HK1050472A1 HK1050472A1 (en) 2003-06-27
HK1050472B true HK1050472B (zh) 2005-07-08

Family

ID=9542727

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03100875.7A HK1050472B (zh) 1999-10-25 2003-02-06 基於醋酸諾美孕酮和雌激素的激素組合物及其用途

Country Status (27)

Country Link
US (2) US8168619B1 (zh)
EP (1) EP1227814B1 (zh)
JP (1) JP5036943B2 (zh)
KR (1) KR100623788B1 (zh)
CN (1) CN100553637C (zh)
AP (1) AP1625A (zh)
AT (1) ATE286400T1 (zh)
AU (1) AU777704B2 (zh)
BR (1) BRPI0014979B8 (zh)
CA (1) CA2389025C (zh)
CZ (1) CZ303248B6 (zh)
DE (1) DE60017281T2 (zh)
DK (1) DK1227814T3 (zh)
ES (1) ES2235967T3 (zh)
HK (1) HK1050472B (zh)
HU (1) HU229382B1 (zh)
IL (2) IL148953A0 (zh)
MX (1) MXPA02004084A (zh)
NO (1) NO327973B1 (zh)
NZ (1) NZ518145A (zh)
OA (1) OA12072A (zh)
PL (1) PL199848B1 (zh)
PT (1) PT1227814E (zh)
RU (1) RU2261106C2 (zh)
SI (1) SI1227814T1 (zh)
WO (2) WO2001030356A1 (zh)
ZA (1) ZA200203398B (zh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2754179B1 (fr) 1996-10-08 1998-12-24 Theramex Nouvelle composition hormononale et son utilisation
WO2001030356A1 (fr) 1999-10-25 2001-05-03 Laboratoire Theramex Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation
FR2814074B1 (fr) * 2000-09-15 2003-03-07 Theramex Nouvelles compositions estro-progestatives topiques a effet systemique
DE60217324T2 (de) 2001-05-18 2007-04-26 Pantarhei Bioscience B.V. Pharmazeutische zusammensetzung für die hormonersatztherapie
ES2337129T3 (es) 2001-05-23 2010-04-21 Pantarhei Bioscience B.V. Sistema de administracion de medicamento comprendiendo un estrogeno tetrahidroxilado para el uso en la anticoncepcion hormonal.
DK1390042T3 (da) 2001-05-23 2008-03-31 Pantarhei Bioscience Bv System for administration af et lægemiddel omfattende tetrahydroxyleret östrogen til anvendelse i hormonal svangerskabsforebyggelse
DE60216630T2 (de) * 2001-11-15 2007-09-20 Pantarhei Bioscience B.V. Verwendung von östrogen in kombination mit progestogen für die hormonsubstitutiionstherapie
CA2489271C (en) 2002-06-11 2011-12-06 Pantarhei Bioscience B.V. Method of treating or preventing immune mediated disorders and pharmaceutical formulation for use therein
AU2003274941A1 (en) 2002-06-11 2003-12-22 Pantarhei Bioscience B.V. A method of treating human skin and a skin care composition for use in such a method
JP2005535624A (ja) * 2002-06-25 2005-11-24 ワイス ホルモン関連症状の治療におけるシクロチオカルバメート誘導体の使用
ES2299730T3 (es) 2002-07-12 2008-06-01 Pantarhei Bioscience B.V. Composicion farmaceutica que comprende derivados de estetrol para el uso en la terapia del cancer.
SI1556058T1 (sl) 2002-10-23 2008-02-29 Pantarhei Bioscience Bv Farmacevtski sestavki, ki obsegajo estetrolne derivate, za uporabo pri zdravljenju raka
DE602008001783D1 (de) 2007-01-08 2010-08-26 Pantarhei Bioscience Bv Verfahren zur behandlung oder prävention von unfruchtbarkeit bei weiblichen säugern und pharmazeutisches kit zur anwendung dieses verfahrens
CN107007611B (zh) * 2017-06-02 2020-04-14 上海市计划生育科学研究所 醋酸诺美孕酮在制备治疗子宫内膜癌的药物中的应用

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826831A (en) * 1983-08-05 1989-05-02 Pre Jay Holdings Limited Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens
JPS61243059A (ja) 1985-04-19 1986-10-29 Konishi Kagaku Kogyo Kk 高純度４，４′−ジヒドロキシジフエニルスルホンの製造法
DE3603644A1 (de) 1986-02-06 1987-08-13 Metabowerke Kg Spannfutter zum einspannen von bohrern oder schlagbohrern
US5208225A (en) * 1986-02-27 1993-05-04 Warner-Lambert Company Compositions containing fixed combinations
ZA87332B (en) 1986-02-27 1987-08-26 Warner Lambert Co Compositions containing fixed combinations
CA1332227C (en) 1987-09-24 1994-10-04 Robert F. Casper Oral contraceptive formulation
US5108995A (en) 1987-09-24 1992-04-28 Jencap Research Ltd. Hormone preparation and method
US5276022A (en) 1987-09-24 1994-01-04 Jencap Research Ltd. Hormone preparation and method
US5256421A (en) 1987-09-24 1993-10-26 Jencap Research Ltd. Hormone preparation and method
FI101601B (fi) 1987-09-24 1998-07-31 Jencap Res Ltd Ehkäisyvalmiste sekä estrogeenin ja progestiinin käyttö ehkäisyvalmist een valmistusmenetelmässä
HUT52382A (en) 1988-03-14 1990-07-28 Sandoz Ag Process for producing pharmaceutical compositions comprising as active ingredient unsubstituted progestin in 19-position and estrogen in the given case
IE71203B1 (en) 1990-12-13 1997-02-12 Akzo Nv Low estrogen oral contraceptives
FR2695826B1 (fr) 1992-09-21 1995-01-06 Theramex Nouvelles compositions pharmaceutiques à base de dérivés de nomégestrol et leurs procédés d'obtention.
US5554601A (en) 1993-11-05 1996-09-10 University Of Florida Methods for neuroprotection
US5552394A (en) 1994-07-22 1996-09-03 The Medical College Of Hampton Roads Low dose oral contraceptives with less breakthrough bleeding and sustained efficacy
US6613757B1 (en) 1994-09-22 2003-09-02 Board Of Regents, The University Of Texas System Combination of prostacyclin with an estrogen or progestin for the prevention and treatment of atherosclerotic vascular disease including preeclampsia and for the treatment of hypertension, and for hormone replacement therapy
SE9403389D0 (sv) 1994-10-06 1994-10-06 Astra Ab Pharmaceutical composition containing derivattves of sex hormones
EP0843555B1 (en) 1995-08-01 2003-08-27 Isis Pharmaceuticals, Inc. Liposomal oligonucleotide compositions
FR2737411B1 (fr) 1995-08-01 1997-10-17 Theramex Nouveaux medicaments hormonaux et leur utilisation pour la correction des carences estrogeniques
US5888543A (en) 1996-07-26 1999-03-30 American Home Products Corporation Oral contraceptives
WO2001030355A1 (fr) 1999-10-25 2001-05-03 Laboratoire Theramex Medicament contraceptif a base d'un progestatif et d'un estrogene et son mode de preparation
FR2754179B1 (fr) 1996-10-08 1998-12-24 Theramex Nouvelle composition hormononale et son utilisation
DE19739916C2 (de) 1997-09-11 2001-09-13 Hesch Rolf Dieter Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen
FR2776191B1 (fr) * 1998-03-23 2002-05-31 Theramex Composition hormonale topique a effet systemique
WO2001030356A1 (fr) 1999-10-25 2001-05-03 Laboratoire Theramex Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation
FR2814074B1 (fr) * 2000-09-15 2003-03-07 Theramex Nouvelles compositions estro-progestatives topiques a effet systemique
PT1443966E (pt) * 2001-11-15 2007-06-21 Pantarhei Bioscience Bv Método para a prevenção ou tratamento das doenças ginecológicas benignas
PE20081895A1 (es) 2007-03-26 2009-01-26 Theramex Regimen anticonceptivo oral

Also Published As

Publication number Publication date
ATE286400T1 (de) 2005-01-15
MXPA02004084A (es) 2003-08-20
OA12072A (fr) 2006-05-04
WO2001030357A1 (fr) 2001-05-03
US20130172300A1 (en) 2013-07-04
JP2003515531A (ja) 2003-05-07
DE60017281T2 (de) 2005-12-08
HK1050472A1 (en) 2003-06-27
NO20021949D0 (no) 2002-04-25
BRPI0014979B1 (pt) 2016-08-02
PT1227814E (pt) 2005-05-31
EP1227814B1 (fr) 2005-01-05
BR0014979A (pt) 2002-11-26
KR100623788B1 (ko) 2006-09-18
IL148953A (en) 2007-06-03
RU2261106C2 (ru) 2005-09-27
AP1625A (en) 2006-07-04
US8168619B1 (en) 2012-05-01
CZ20021427A3 (cs) 2002-08-14
PL199848B1 (pl) 2008-11-28
DE60017281D1 (de) 2005-02-10
SI1227814T1 (en) 2005-06-30
DK1227814T3 (da) 2005-04-11
NO327973B1 (no) 2009-11-02
HUP0203721A2 (hu) 2003-03-28
NZ518145A (en) 2005-01-28
BRPI0014979B8 (pt) 2021-05-25
AU1032601A (en) 2001-05-08
RU2002113652A (ru) 2004-03-27
PL356847A1 (en) 2004-07-12
CN100553637C (zh) 2009-10-28
CA2389025C (fr) 2009-12-08
KR20020057979A (ko) 2002-07-12
ZA200203398B (en) 2003-12-03
CN1382053A (zh) 2002-11-27
HUP0203721A3 (en) 2003-07-28
NO20021949L (no) 2002-04-25
ES2235967T3 (es) 2005-07-16
HU229382B1 (hu) 2013-11-28
IL148953A0 (en) 2002-11-10
WO2001030356A1 (fr) 2001-05-03
CA2389025A1 (fr) 2001-05-03
CZ303248B6 (cs) 2012-06-20
JP5036943B2 (ja) 2012-09-26
AU777704B2 (en) 2004-10-28
US9084796B2 (en) 2015-07-21
AP2002002475A0 (en) 2002-06-30
EP1227814A1 (fr) 2002-08-07

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20191024