HUP0203721A2 - Új hormonkészítmény és alkalmazása - Google Patents

Új hormonkészítmény és alkalmazása

Info

Publication number
HUP0203721A2
HUP0203721A2 HU0203721A HUP0203721A HUP0203721A2 HU P0203721 A2 HUP0203721 A2 HU P0203721A2 HU 0203721 A HU0203721 A HU 0203721A HU P0203721 A HUP0203721 A HU P0203721A HU P0203721 A2 HUP0203721 A2 HU P0203721A2
Authority
HU
Hungary
Prior art keywords
dose
hormonal composition
progestogen
component
estrogen
Prior art date
Application number
HU0203721A
Other languages
English (en)
Inventor
Jacques Paris
Jean-Louis Thomas
Original Assignee
Laboratoire Theramex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Theramex filed Critical Laboratoire Theramex
Publication of HUP0203721A2 publication Critical patent/HUP0203721A2/hu
Publication of HUP0203721A3 publication Critical patent/HUP0203721A3/hu
Publication of HU229382B1 publication Critical patent/HU229382B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

A találmány tárgya gyógyszerészeti hormonkészítmények, amelyekorálisan adagolhatók, kombinált ösztrogén-progesztogén keverékbőlállnak, amelyek lehetővé teszik egy ösztrogén komponens 0,3-3 mgközötti dózisban történő és egy 19-norprogeszteron-származékprogesztogén komponens 0,3-1 ,5 mg közötti dózisban történő egyidejűadagolását egy vagy több nemtoxikus, inert, gyógyszerészetilegalkalmazható hordozóanyaggal együtt vagy azzal összekeverve. Ó
HU0203721A 1999-10-25 2000-10-24 Egy ösztrogénen és nomegesztrol acetáton alapuló hormonkészítmény alkalmazása HU229382B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/FR1999/002588 WO2001030356A1 (fr) 1999-10-25 1999-10-25 Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation
PCT/FR2000/002939 WO2001030357A1 (fr) 1999-10-25 2000-10-24 Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation

Publications (3)

Publication Number Publication Date
HUP0203721A2 true HUP0203721A2 (hu) 2003-03-28
HUP0203721A3 HUP0203721A3 (en) 2003-07-28
HU229382B1 HU229382B1 (hu) 2013-11-28

Family

ID=9542727

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0203721A HU229382B1 (hu) 1999-10-25 2000-10-24 Egy ösztrogénen és nomegesztrol acetáton alapuló hormonkészítmény alkalmazása

Country Status (27)

Country Link
US (2) US8168619B1 (hu)
EP (1) EP1227814B1 (hu)
JP (1) JP5036943B2 (hu)
KR (1) KR100623788B1 (hu)
CN (1) CN100553637C (hu)
AP (1) AP1625A (hu)
AT (1) ATE286400T1 (hu)
AU (1) AU777704B2 (hu)
BR (1) BRPI0014979B8 (hu)
CA (1) CA2389025C (hu)
CZ (1) CZ303248B6 (hu)
DE (1) DE60017281T2 (hu)
DK (1) DK1227814T3 (hu)
ES (1) ES2235967T3 (hu)
HK (1) HK1050472B (hu)
HU (1) HU229382B1 (hu)
IL (2) IL148953A0 (hu)
MX (1) MXPA02004084A (hu)
NO (1) NO327973B1 (hu)
NZ (1) NZ518145A (hu)
OA (1) OA12072A (hu)
PL (1) PL199848B1 (hu)
PT (1) PT1227814E (hu)
RU (1) RU2261106C2 (hu)
SI (1) SI1227814T1 (hu)
WO (2) WO2001030356A1 (hu)
ZA (1) ZA200203398B (hu)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2754179B1 (fr) 1996-10-08 1998-12-24 Theramex Nouvelle composition hormononale et son utilisation
WO2001030356A1 (fr) 1999-10-25 2001-05-03 Laboratoire Theramex Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation
FR2814074B1 (fr) * 2000-09-15 2003-03-07 Theramex Nouvelles compositions estro-progestatives topiques a effet systemique
WO2002094276A1 (en) 2001-05-18 2002-11-28 Pantarhei Bioscience B.V. Pharmaceutical composition for use in hormone replacement therapy
ATE449606T1 (de) 2001-05-23 2009-12-15 Pantarhei Bioscience Bv Tetrahydroxylierte estrogen enthaltendes arzneistoffverabreichungssystem zur verwendung in hormonalen kontrazeption
DE60223795T2 (de) 2001-05-23 2008-11-27 Pantarhei Bioscience B.V. Tetrahydroxyliertes Östrogen enthaltendes Arzneistoffverabreichungssystem zur Verwendung in der hormonalen Kontrazeption
PT1446128E (pt) * 2001-11-15 2007-03-30 Pantarhei Bioscience Bv Utilização de compostos estrogénicos combinados com compostos progestagénicos na terapia hormonal de substituição
WO2003103685A1 (en) 2002-06-11 2003-12-18 Pantarhei Bioscience B.V. A method of treating human skin and a skin care composition for use in such a method
EP1511496B1 (en) 2002-06-11 2006-09-27 Pantarhei Bioscience B.V. Method of treating or preventing immune mediated disorders and pharmaceutical formulation for use therein
EP1515725A4 (en) * 2002-06-25 2005-09-21 Wyeth Corp USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN THE TREATMENT OF HORMONE-RELATED ILLNESSES
SI1526856T1 (sl) 2002-07-12 2008-04-30 Pantarhei Bioscience Bv Farmacevtski sestavek, ki obsega estetrolne derivate za uporabo pri zdravljenju raka
WO2004037269A1 (en) 2002-10-23 2004-05-06 Pantarhei Bioscience B.V. Pharmaceutical compositions comprising estetrol derivatives for use in cancer therapy
US8236785B2 (en) 2007-01-08 2012-08-07 Pantarhei Bioscience B.V. Method of treating or preventing infertility in a female mammal and pharmaceutical kit for use in such method
CN107007611B (zh) * 2017-06-02 2020-04-14 上海市计划生育科学研究所 醋酸诺美孕酮在制备治疗子宫内膜癌的药物中的应用

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826831A (en) * 1983-08-05 1989-05-02 Pre Jay Holdings Limited Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens
JPS61243059A (ja) 1985-04-19 1986-10-29 Konishi Kagaku Kogyo Kk 高純度４，４′−ジヒドロキシジフエニルスルホンの製造法
DE3603644A1 (de) 1986-02-06 1987-08-13 Metabowerke Kg Spannfutter zum einspannen von bohrern oder schlagbohrern
ZA87332B (en) 1986-02-27 1987-08-26 Warner Lambert Co Compositions containing fixed combinations
US5208225A (en) * 1986-02-27 1993-05-04 Warner-Lambert Company Compositions containing fixed combinations
US5108995A (en) 1987-09-24 1992-04-28 Jencap Research Ltd. Hormone preparation and method
CA1332227C (en) 1987-09-24 1994-10-04 Robert F. Casper Oral contraceptive formulation
US5276022A (en) 1987-09-24 1994-01-04 Jencap Research Ltd. Hormone preparation and method
US5256421A (en) 1987-09-24 1993-10-26 Jencap Research Ltd. Hormone preparation and method
ES2169030T3 (es) 1987-09-24 2002-07-01 Jencap Res Ltd Envases de anticonceptivos que contienen estrogeno y progestina.
HUT52382A (en) 1988-03-14 1990-07-28 Sandoz Ag Process for producing pharmaceutical compositions comprising as active ingredient unsubstituted progestin in 19-position and estrogen in the given case
IE71203B1 (en) 1990-12-13 1997-02-12 Akzo Nv Low estrogen oral contraceptives
FR2695826B1 (fr) 1992-09-21 1995-01-06 Theramex Nouvelles compositions pharmaceutiques à base de dérivés de nomégestrol et leurs procédés d'obtention.
US5554601A (en) 1993-11-05 1996-09-10 University Of Florida Methods for neuroprotection
US5552394A (en) 1994-07-22 1996-09-03 The Medical College Of Hampton Roads Low dose oral contraceptives with less breakthrough bleeding and sustained efficacy
US6613757B1 (en) 1994-09-22 2003-09-02 Board Of Regents, The University Of Texas System Combination of prostacyclin with an estrogen or progestin for the prevention and treatment of atherosclerotic vascular disease including preeclampsia and for the treatment of hypertension, and for hormone replacement therapy
SE9403389D0 (sv) 1994-10-06 1994-10-06 Astra Ab Pharmaceutical composition containing derivattves of sex hormones
DE69629702T2 (de) 1995-08-01 2004-06-17 Isis Pharmaceuticals, Inc., Carlsbad Liposomale oligonukleotidzusammensetzungen
FR2737411B1 (fr) 1995-08-01 1997-10-17 Theramex Nouveaux medicaments hormonaux et leur utilisation pour la correction des carences estrogeniques
US5888543A (en) 1996-07-26 1999-03-30 American Home Products Corporation Oral contraceptives
FR2754179B1 (fr) 1996-10-08 1998-12-24 Theramex Nouvelle composition hormononale et son utilisation
WO2001030355A1 (fr) 1999-10-25 2001-05-03 Laboratoire Theramex Medicament contraceptif a base d'un progestatif et d'un estrogene et son mode de preparation
DE19739916C2 (de) 1997-09-11 2001-09-13 Hesch Rolf Dieter Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen
FR2776191B1 (fr) * 1998-03-23 2002-05-31 Theramex Composition hormonale topique a effet systemique
WO2001030356A1 (fr) 1999-10-25 2001-05-03 Laboratoire Theramex Composition hormonale a base d'un progestatif et d'un estrogene et son utilisation
FR2814074B1 (fr) * 2000-09-15 2003-03-07 Theramex Nouvelles compositions estro-progestatives topiques a effet systemique
ATE356635T1 (de) * 2001-11-15 2007-04-15 Pantarhei Bioscience Bv Verfahren zur vorbeugung oder behandlung von benignen gynäkologischen störungen
AR065816A1 (es) 2007-03-26 2009-07-01 Theramex Regimen anticonceptivo oral

Also Published As

Publication number Publication date
HK1050472B (zh) 2005-07-08
CN1382053A (zh) 2002-11-27
WO2001030356A1 (fr) 2001-05-03
DE60017281T2 (de) 2005-12-08
CA2389025A1 (fr) 2001-05-03
HUP0203721A3 (en) 2003-07-28
MXPA02004084A (es) 2003-08-20
US9084796B2 (en) 2015-07-21
PT1227814E (pt) 2005-05-31
WO2001030357A1 (fr) 2001-05-03
CZ303248B6 (cs) 2012-06-20
RU2002113652A (ru) 2004-03-27
CN100553637C (zh) 2009-10-28
IL148953A (en) 2007-06-03
US8168619B1 (en) 2012-05-01
KR100623788B1 (ko) 2006-09-18
JP5036943B2 (ja) 2012-09-26
HK1050472A1 (en) 2003-06-27
DE60017281D1 (de) 2005-02-10
AU777704B2 (en) 2004-10-28
PL356847A1 (en) 2004-07-12
KR20020057979A (ko) 2002-07-12
EP1227814A1 (fr) 2002-08-07
DK1227814T3 (da) 2005-04-11
NZ518145A (en) 2005-01-28
BRPI0014979B8 (pt) 2021-05-25
AP1625A (en) 2006-07-04
ZA200203398B (en) 2003-12-03
PL199848B1 (pl) 2008-11-28
NO20021949D0 (no) 2002-04-25
JP2003515531A (ja) 2003-05-07
BRPI0014979B1 (pt) 2016-08-02
EP1227814B1 (fr) 2005-01-05
CA2389025C (fr) 2009-12-08
AU1032601A (en) 2001-05-08
NO20021949L (no) 2002-04-25
ES2235967T3 (es) 2005-07-16
HU229382B1 (hu) 2013-11-28
US20130172300A1 (en) 2013-07-04
SI1227814T1 (en) 2005-06-30
RU2261106C2 (ru) 2005-09-27
BR0014979A (pt) 2002-11-26
AP2002002475A0 (en) 2002-06-30
IL148953A0 (en) 2002-11-10
NO327973B1 (no) 2009-11-02
ATE286400T1 (de) 2005-01-15
OA12072A (fr) 2006-05-04
CZ20021427A3 (cs) 2002-08-14

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Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: THERAMEX HQ UK LIMITED, GB

Free format text: FORMER OWNER(S): LABORATOIRE THERAMEX, MC; TEVA PHARMACEUTICALS INTERNATIONAL GMBH, CH

MM4A Lapse of definitive patent protection due to non-payment of fees