DK1222207T3 - C-peptid til forbedret fremstilling af insulin og insulinanaloge - Google Patents

C-peptid til forbedret fremstilling af insulin og insulinanaloge

Info

Publication number
DK1222207T3
DK1222207T3 DK00960664T DK00960664T DK1222207T3 DK 1222207 T3 DK1222207 T3 DK 1222207T3 DK 00960664 T DK00960664 T DK 00960664T DK 00960664 T DK00960664 T DK 00960664T DK 1222207 T3 DK1222207 T3 DK 1222207T3
Authority
DK
Denmark
Prior art keywords
insulin
chain
amino acid
human insulin
peptide
Prior art date
Application number
DK00960664T
Other languages
Danish (da)
English (en)
Inventor
Paul Habermann
Johannes Meiwes
Gerhard Seipke
Johann Ertl
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Application granted granted Critical
Publication of DK1222207T3 publication Critical patent/DK1222207T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
DK00960664T 1999-10-02 2000-09-15 C-peptid til forbedret fremstilling af insulin og insulinanaloge DK1222207T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19947456A DE19947456A1 (de) 1999-10-02 1999-10-02 C-Peptid zur verbesserten Herstellung von Insulin und Insulinanaloga
PCT/EP2000/009017 WO2001025278A1 (de) 1999-10-02 2000-09-15 C-peptid zur verbesserten herstellung von insulin und insulinanaloga

Publications (1)

Publication Number Publication Date
DK1222207T3 true DK1222207T3 (da) 2008-03-17

Family

ID=7924253

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00960664T DK1222207T3 (da) 1999-10-02 2000-09-15 C-peptid til forbedret fremstilling af insulin og insulinanaloge

Country Status (25)

Country Link
US (1) US6534288B1 (pt)
EP (1) EP1222207B1 (pt)
JP (1) JP4681784B2 (pt)
KR (1) KR100823463B1 (pt)
CN (1) CN1193042C (pt)
AT (1) ATE380196T1 (pt)
AU (1) AU778369B2 (pt)
BR (2) BRPI0014464B8 (pt)
CA (1) CA2385857C (pt)
CY (1) CY1107860T1 (pt)
DE (2) DE19947456A1 (pt)
DK (1) DK1222207T3 (pt)
ES (1) ES2295054T3 (pt)
HK (1) HK1049016B (pt)
HU (1) HU228313B1 (pt)
IL (2) IL148942A0 (pt)
MX (1) MXPA02003103A (pt)
NO (1) NO329975B1 (pt)
NZ (1) NZ518066A (pt)
PL (1) PL203195B1 (pt)
PT (1) PT1222207E (pt)
SI (1) SI1222207T1 (pt)
TW (1) TWI265168B (pt)
WO (1) WO2001025278A1 (pt)
ZA (1) ZA200202520B (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7176278B2 (en) 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
US20050250676A1 (en) * 2001-11-19 2005-11-10 Aventis Pharma Deutschland Gmbh Method of activating insulin receptor substrate-2 to stimulate insulin production
US20040038864A1 (en) * 2002-06-27 2004-02-26 Per Balschmidt Use of dimethyl sulfone as isotonicity agent
DE10235168A1 (de) * 2002-08-01 2004-02-12 Aventis Pharma Deutschland Gmbh Verfahren zur Reinigung von Preproinsulin
JP5697831B2 (ja) * 2003-12-03 2015-04-08 ノヴォ ノルディスク アー／エス 単鎖インシュリン
CN1663960B (zh) * 2004-03-01 2012-07-04 重庆富进生物医药有限公司 高效表达重组人胰岛素原及其类似物的新型c肽
WO2007121318A2 (en) * 2006-04-12 2007-10-25 Emisphere Technologies, Inc. Formulations for delivering insulin
KR20100111682A (ko) * 2008-01-09 2010-10-15 사노피-아벤티스 도이칠란트 게엠베하 극히 지연된 시간-작용 프로필을 갖는 신규 인슐린 유도체
EP2229406B1 (de) 2008-01-09 2015-04-22 Sanofi-Aventis Deutschland GmbH Neue insulinderivate mit extrem verzögertem zeit- / wirkungsprofil
DE102008003568A1 (de) 2008-01-09 2009-07-16 Sanofi-Aventis Deutschland Gmbh Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
DE102008025007A1 (de) 2008-05-24 2009-11-26 Sanofi-Aventis Deutschland Gmbh Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
DE102008025008A1 (de) 2008-05-24 2009-11-26 Sanofi-Aventis Deutschland Gmbh Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
DE102008003566A1 (de) 2008-01-09 2009-07-16 Sanofi-Aventis Deutschland Gmbh Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
PT2349324T (pt) 2008-10-17 2017-12-06 Sanofi Aventis Deutschland Combinação de uma insulina e de um agonista do glp-1
PL2498802T3 (pl) 2009-11-13 2015-06-30 Sanofi Aventis Deutschland Kompozycja farmaceutyczna zawierająca agonistę GLP-1, insulinę i metioninę
EP2498801B1 (de) 2009-11-13 2018-01-24 Sanofi-Aventis Deutschland GmbH HARMAZEUTISCHE ZUSAMMENSETZUNG UMFASSEND desPro36Exendin-4(1-39)-Lys6-NH2 UND METHIONIN
EP2611458B1 (en) 2010-08-30 2016-09-21 Sanofi-Aventis Deutschland GmbH Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
BR112014004726A2 (pt) 2011-08-29 2017-04-04 Sanofi Aventis Deutschland combinação farmacêutica para uso no controle glicêmico em pacientes de diabetes tipo 2
AR087744A1 (es) 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
TWI641381B (zh) 2013-02-04 2018-11-21 法商賽諾菲公司 胰島素類似物及／或胰島素衍生物之穩定化醫藥調配物
JP6735674B2 (ja) 2014-01-09 2020-08-05 サノフイＳａｎｏｆｉ インスリンアスパルトの安定化された医薬製剤
MX2016008978A (es) 2014-01-09 2016-10-04 Sanofi Sa Formulaciones farmaceuticas de analogos de insulina y/o derivados de insulina estabilizadas y que estan libres de glicerol.
US9839692B2 (en) 2014-01-09 2017-12-12 Sanofi Stabilized pharmaceutical formulations of insulin analogues and/or insulin derivatives
EP3229828B1 (en) 2014-12-12 2023-04-05 Sanofi-Aventis Deutschland GmbH Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH16156A (en) * 1980-03-27 1983-07-18 Lilly Co Eli Process for producing an insulin precursor
US4430266A (en) * 1980-11-28 1984-02-07 Eli Lilly And Company Process for producing an insulin precursor
HRP940432B1 (en) * 1994-08-05 2003-10-31 Pliva Pharm & Chem Works Dna sequences encoding biosynthetic insulin precursors and process for preparation of insulin
PT821006E (pt) * 1996-07-26 2004-09-30 Aventis Pharma Gmbh Derivados de insulina com ligacao a zinco aumentada
DE19726167B4 (de) * 1997-06-20 2008-01-24 Sanofi-Aventis Deutschland Gmbh Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung

Also Published As

Publication number Publication date
IL148942A (en) 2010-02-17
EP1222207A1 (de) 2002-07-17
HU228313B1 (en) 2013-03-28
CA2385857C (en) 2012-05-22
HUP0202755A2 (hu) 2002-12-28
BRPI0014464B1 (pt) 2018-03-13
ATE380196T1 (de) 2007-12-15
PL354078A1 (en) 2003-12-15
HK1049016A1 (en) 2003-04-25
JP2003511018A (ja) 2003-03-25
IL148942A0 (en) 2002-09-12
DE50014830D1 (de) 2008-01-17
EP1222207B1 (de) 2007-12-05
HUP0202755A3 (en) 2005-01-28
KR100823463B1 (ko) 2008-04-21
DE19947456A1 (de) 2001-04-05
ZA200202520B (en) 2002-12-24
CA2385857A1 (en) 2001-04-12
BRPI0014464B8 (pt) 2021-05-25
SI1222207T1 (sl) 2008-04-30
NZ518066A (en) 2004-05-28
NO20021335L (no) 2002-06-03
TWI265168B (en) 2006-11-01
BR0014464A (pt) 2002-06-11
PT1222207E (pt) 2008-02-11
CN1377370A (zh) 2002-10-30
ES2295054T3 (es) 2008-04-16
NO329975B1 (no) 2011-01-31
WO2001025278A1 (de) 2001-04-12
MXPA02003103A (es) 2002-09-30
CY1107860T1 (el) 2013-06-19
AU778369B2 (en) 2004-12-02
NO20021335D0 (no) 2002-03-18
US6534288B1 (en) 2003-03-18
HK1049016B (zh) 2005-10-14
PL203195B1 (pl) 2009-09-30
KR20020047209A (ko) 2002-06-21
AU7287700A (en) 2001-05-10
CN1193042C (zh) 2005-03-16
JP4681784B2 (ja) 2011-05-11

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