DK1217001T3 - Quinuclidinforbindelser og lægemidler indeholdende dem som den aktive bestanddel - Google Patents
Quinuclidinforbindelser og lægemidler indeholdende dem som den aktive bestanddelInfo
- Publication number
- DK1217001T3 DK1217001T3 DK00962889T DK00962889T DK1217001T3 DK 1217001 T3 DK1217001 T3 DK 1217001T3 DK 00962889 T DK00962889 T DK 00962889T DK 00962889 T DK00962889 T DK 00962889T DK 1217001 T3 DK1217001 T3 DK 1217001T3
- Authority
- DK
- Denmark
- Prior art keywords
- optionally substituted
- chain
- substituted
- denotes
- represented
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP27390599 | 1999-09-28 | ||
| JP2000179352 | 2000-06-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1217001T3 true DK1217001T3 (da) | 2006-03-20 |
Family
ID=26550809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00962889T DK1217001T3 (da) | 1999-09-28 | 2000-09-27 | Quinuclidinforbindelser og lægemidler indeholdende dem som den aktive bestanddel |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6599917B1 (pt) |
| EP (1) | EP1217001B1 (pt) |
| JP (1) | JP4206212B2 (pt) |
| KR (1) | KR100694687B1 (pt) |
| CN (1) | CN100334085C (pt) |
| AT (1) | ATE312100T1 (pt) |
| AU (1) | AU782114B2 (pt) |
| BR (1) | BR0014331A (pt) |
| CA (1) | CA2385995C (pt) |
| DE (1) | DE60024651T2 (pt) |
| DK (1) | DK1217001T3 (pt) |
| ES (1) | ES2252063T3 (pt) |
| HU (1) | HUP0203514A3 (pt) |
| IL (2) | IL148631A0 (pt) |
| MX (1) | MXPA02003167A (pt) |
| NO (1) | NO328218B1 (pt) |
| NZ (1) | NZ517788A (pt) |
| RU (1) | RU2266905C2 (pt) |
| TW (1) | TWI282794B (pt) |
| WO (1) | WO2001023383A1 (pt) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0010955D0 (en) * | 2000-05-05 | 2000-06-28 | Novartis Ag | Organic compounds |
| WO2002076973A1 (fr) * | 2001-03-27 | 2002-10-03 | Eisai Co., Ltd. | Derive d'amine cyclique a substitution n-aryle et medicament contenant ledit derive en tant que principe actif |
| EP1256573A1 (en) | 2001-05-09 | 2002-11-13 | Eisai Co., Ltd. | Process for producing stereoisomer of pyrrolidine derivative |
| CZ2004501A3 (cs) * | 2001-10-17 | 2004-09-15 | Ucb, S.A. | Chinuklidinové deriváty, způsoby jejich přípravy a jejich použití jako M2 a/nebo M3 inhibitoru muskarinového receptoru |
| US7361671B2 (en) * | 2001-11-15 | 2008-04-22 | The Institute For Pharmaceutical Discovery, Inc. | Substituted heteroarylalkanoic acids |
| DE10225537A1 (de) * | 2002-06-10 | 2003-12-18 | Bayer Ag | N-alkylierte Thiazoliumsalze und Verfahren zu deren Herstellung |
| GB0218876D0 (en) * | 2002-08-13 | 2002-09-25 | Merck Sharp & Dohme | Therapeutic agents |
| CA2499128C (en) | 2002-09-25 | 2012-07-31 | Memory Pharmaceuticals Corporation | Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof |
| DE10334724A1 (de) * | 2003-07-30 | 2005-02-24 | Bayer Healthcare Ag | N-Biarylamide |
| JP4667384B2 (ja) * | 2003-10-07 | 2011-04-13 | レノビス， インコーポレイテッド | イオンチャネルリガンドとしてのアミド誘導体および薬学的組成物、ならびにこれらを使用する方法 |
| MXPA06010852A (es) | 2004-03-25 | 2007-01-16 | Memory Pharm Corp | Indazoles, benzotiazoles, benzoisotiazoles, bencisoxazoles y preparacion y usos de los mismos. |
| US8106066B2 (en) | 2005-09-23 | 2012-01-31 | Memory Pharmaceuticals Corporation | Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof |
| JP2010519328A (ja) | 2007-02-26 | 2010-06-03 | ファイザー・プロダクツ・インク | Ｈ−ｐｇｄｓの阻害剤としてのニコチンアミド誘導体およびプロスタグランジンｄ２が媒介する疾患の治療のためのそれらの使用 |
| TW201111385A (en) | 2009-08-27 | 2011-04-01 | Biocryst Pharm Inc | Heterocyclic compounds as janus kinase inhibitors |
| US8420661B2 (en) * | 2010-04-13 | 2013-04-16 | Hoffmann-La Roche Inc. | Arylethynyl derivatives |
| AU2011258005A1 (en) | 2010-05-28 | 2013-01-17 | Biocryst Pharmaceuticals, Inc. | Heterocyclic compounds as Janus kinase inhibitors |
| SG11201403645VA (en) | 2011-12-28 | 2014-07-30 | Global Blood Therapeutics Inc | Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation |
| EP2797597B1 (en) | 2011-12-28 | 2020-02-26 | Global Blood Therapeutics, Inc. | Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation |
| WO2014060381A1 (de) | 2012-10-18 | 2014-04-24 | Bayer Cropscience Ag | Heterocyclische verbindungen als schädlingsbekämpfungsmittel |
| EP2914587A1 (de) | 2012-10-31 | 2015-09-09 | Bayer CropScience AG | Neue heterocylische verbindungen als schädlingsbekämpfungsmittel |
| US9802900B2 (en) | 2013-03-15 | 2017-10-31 | Global Blood Therapeutics, Inc. | Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin |
| US9422279B2 (en) | 2013-03-15 | 2016-08-23 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US20140274961A1 (en) | 2013-03-15 | 2014-09-18 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US9604999B2 (en) | 2013-03-15 | 2017-03-28 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US10266551B2 (en) | 2013-03-15 | 2019-04-23 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| CA2902711C (en) | 2013-03-15 | 2021-07-06 | Global Blood Therapeutics, Inc. | Substituted pyridinyl-6-methoxy-2-hydroxybenzaldehyde derivatives and pharmaceutical compositions thereof useful for the modulation of hemoglobin |
| US8952171B2 (en) | 2013-03-15 | 2015-02-10 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| AU2014237340C1 (en) | 2013-03-15 | 2018-11-08 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| EA033555B1 (ru) | 2013-03-15 | 2019-10-31 | Global Blood Therapeutics Inc | Фармацевтические композиции для лечения серповидно-клеточного нарушения |
| US9458139B2 (en) | 2013-03-15 | 2016-10-04 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| WO2014145040A1 (en) | 2013-03-15 | 2014-09-18 | Global Blood Therapeutics, Inc. | Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation |
| EA201992707A1 (ru) | 2013-11-18 | 2020-06-30 | Глобал Блад Терапьютикс, Инк. | Соединения и их применения для модуляции гемоглобина |
| AP2016009261A0 (en) | 2014-02-07 | 2016-06-30 | Global Blood Therapeutics Inc | Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde |
| MA41841A (fr) | 2015-03-30 | 2018-02-06 | Global Blood Therapeutics Inc | Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs |
| PT3303316T (pt) | 2015-06-03 | 2020-04-27 | Hoffmann La Roche | Derivados de etinilo |
| WO2017096230A1 (en) | 2015-12-04 | 2017-06-08 | Global Blood Therapeutics, Inc. | Dosing regimens for 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde |
| TWI825524B (zh) | 2016-05-12 | 2023-12-11 | 美商全球血液治療公司 | 用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法 |
| TWI778983B (zh) | 2016-10-12 | 2022-10-01 | 美商全球血液治療公司 | 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑 |
| US20200115389A1 (en) | 2018-09-18 | 2020-04-16 | Nikang Therapeutics, Inc. | Fused tricyclic ring derivatives as src homology-2 phosphatase inhibitors |
| ES2966707T3 (es) | 2018-10-01 | 2024-04-23 | Global Blood Therapeutics Inc | Moduladores de la hemoglobina para el tratamiento de la drepanocitosis |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1752792A (en) | 1991-03-08 | 1992-10-06 | Rhone-Poulenc Rorer International (Holdings) Inc. | Multicyclic tertiary amine polyaromatic squalene synthetase inhibitors |
| US5135935A (en) * | 1991-05-17 | 1992-08-04 | Merck & Co., Inc. | Squalene synthetase inhibitors |
| GB9127279D0 (en) | 1991-12-23 | 1992-02-19 | Ici Plc | Heterocyclic derivatives |
| JPH05310732A (ja) | 1992-03-12 | 1993-11-22 | Mitsubishi Kasei Corp | シンノリン−３−カルボン酸誘導体 |
| GB9207961D0 (en) * | 1992-04-10 | 1992-05-27 | Ici Plc | Heterocyclic derivatives |
| GB9218334D0 (en) * | 1992-08-28 | 1992-10-14 | Ici Plc | Heterocyclic compounds |
| WO1995031458A1 (en) | 1992-10-13 | 1995-11-23 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | 3-hydroxyquinuclidin-3-ylphenylquinolines as squalene synthase inhibitors |
| GB9226573D0 (en) | 1992-12-21 | 1993-02-17 | Ici Plc | Heterocyclic compounds |
| IL109451A0 (en) | 1993-04-29 | 1994-07-31 | Zeneca Ltd | Heterocyclic derivatives |
| GB9412145D0 (en) * | 1994-06-17 | 1994-08-10 | Zeneca Ltd | Heterocycles |
| JPH08134067A (ja) * | 1994-11-11 | 1996-05-28 | Yamanouchi Pharmaceut Co Ltd | キヌクリジン誘導体 |
| JPH08269056A (ja) * | 1995-03-29 | 1996-10-15 | Chugai Pharmaceut Co Ltd | スクアレンシンセターゼ阻害作用を有するキヌクリジン誘導体 |
| US5712270A (en) * | 1995-11-06 | 1998-01-27 | American Home Products Corporation | 2-arylamidothiazole derivatives with CNS activity |
| WO1997044339A1 (en) * | 1996-05-20 | 1997-11-27 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
-
2000
- 2000-09-27 AU AU74464/00A patent/AU782114B2/en not_active Ceased
- 2000-09-27 CA CA002385995A patent/CA2385995C/en not_active Expired - Fee Related
- 2000-09-27 JP JP2001526535A patent/JP4206212B2/ja not_active Expired - Fee Related
- 2000-09-27 DE DE60024651T patent/DE60024651T2/de not_active Expired - Lifetime
- 2000-09-27 CN CNB00813541XA patent/CN100334085C/zh not_active Expired - Fee Related
- 2000-09-27 TW TW089119958A patent/TWI282794B/zh not_active IP Right Cessation
- 2000-09-27 BR BR0014331-6A patent/BR0014331A/pt not_active Application Discontinuation
- 2000-09-27 WO PCT/JP2000/006665 patent/WO2001023383A1/ja active IP Right Grant
- 2000-09-27 RU RU2002111344/04A patent/RU2266905C2/ru not_active IP Right Cessation
- 2000-09-27 EP EP00962889A patent/EP1217001B1/en not_active Expired - Lifetime
- 2000-09-27 AT AT00962889T patent/ATE312100T1/de not_active IP Right Cessation
- 2000-09-27 IL IL14863100A patent/IL148631A0/xx unknown
- 2000-09-27 NZ NZ517788A patent/NZ517788A/en not_active IP Right Cessation
- 2000-09-27 HU HU0203514A patent/HUP0203514A3/hu unknown
- 2000-09-27 ES ES00962889T patent/ES2252063T3/es not_active Expired - Lifetime
- 2000-09-27 MX MXPA02003167A patent/MXPA02003167A/es active IP Right Grant
- 2000-09-27 US US10/088,554 patent/US6599917B1/en not_active Expired - Fee Related
- 2000-09-27 KR KR1020027003952A patent/KR100694687B1/ko not_active IP Right Cessation
- 2000-09-27 DK DK00962889T patent/DK1217001T3/da active
-
2002
- 2002-03-12 IL IL148631A patent/IL148631A/en not_active IP Right Cessation
- 2002-03-26 NO NO20021528A patent/NO328218B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100694687B1 (ko) | 2007-03-13 |
| RU2266905C2 (ru) | 2005-12-27 |
| HUP0203514A2 (hu) | 2003-03-28 |
| KR20020034197A (ko) | 2002-05-08 |
| DE60024651D1 (de) | 2006-01-12 |
| ATE312100T1 (de) | 2005-12-15 |
| CN100334085C (zh) | 2007-08-29 |
| TWI282794B (en) | 2007-06-21 |
| HUP0203514A3 (en) | 2004-01-28 |
| NZ517788A (en) | 2003-11-28 |
| IL148631A0 (en) | 2002-09-12 |
| WO2001023383A1 (fr) | 2001-04-05 |
| JP4206212B2 (ja) | 2009-01-07 |
| EP1217001A4 (en) | 2002-12-18 |
| IL148631A (en) | 2010-04-29 |
| NO20021528L (no) | 2002-05-28 |
| AU782114B2 (en) | 2005-07-07 |
| CN1377349A (zh) | 2002-10-30 |
| NO20021528D0 (no) | 2002-03-26 |
| ES2252063T3 (es) | 2006-05-16 |
| CA2385995C (en) | 2009-06-16 |
| CA2385995A1 (en) | 2001-04-05 |
| AU7446400A (en) | 2001-04-30 |
| MXPA02003167A (es) | 2003-10-06 |
| BR0014331A (pt) | 2003-06-10 |
| EP1217001A1 (en) | 2002-06-26 |
| DE60024651T2 (de) | 2006-09-28 |
| EP1217001B1 (en) | 2005-12-07 |
| NO328218B1 (no) | 2010-01-11 |
| US6599917B1 (en) | 2003-07-29 |
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