DE60223904D1 - Benzylaminanalogen - Google Patents
BenzylaminanalogenInfo
- Publication number
- DE60223904D1 DE60223904D1 DE60223904T DE60223904T DE60223904D1 DE 60223904 D1 DE60223904 D1 DE 60223904D1 DE 60223904 T DE60223904 T DE 60223904T DE 60223904 T DE60223904 T DE 60223904T DE 60223904 D1 DE60223904 D1 DE 60223904D1
- Authority
- DE
- Germany
- Prior art keywords
- represent
- different
- same
- alkyl group
- sulfur
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C07C219/30—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
- C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/44—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/20—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C333/02—Monothiocarbamic acids; Derivatives thereof
- C07C333/04—Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/68—One oxygen atom attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Applications Claiming Priority (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001018386 | 2001-01-26 | ||
JP2001018386 | 2001-01-26 | ||
JP2001305182 | 2001-10-01 | ||
JP2001305182 | 2001-10-01 | ||
PCT/JP2002/000400 WO2002059074A1 (fr) | 2001-01-26 | 2002-01-22 | Analogue de benzylamine |
JP2002015136A JP4176997B2 (ja) | 2001-01-26 | 2002-01-24 | ヒドロキシベンジルアミン誘導体 |
TW91101231 | 2002-01-25 | ||
JP2002214641 | 2002-07-24 | ||
JP2003200434A JP2004107322A (ja) | 2001-01-26 | 2003-07-23 | ヒドロキシベンジルアミン誘導体を含有する医薬 |
US10/629,108 US7504437B2 (en) | 2001-01-26 | 2003-07-28 | Benzylamine analogues |
US11/583,499 US7514475B2 (en) | 2001-01-26 | 2006-10-19 | Benzylamine analogues |
US11/820,218 US20080255095A1 (en) | 2001-01-26 | 2007-06-18 | Benzylamine analogues |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60223904D1 true DE60223904D1 (de) | 2008-01-17 |
DE60223904T2 DE60223904T2 (de) | 2008-11-27 |
Family
ID=32300480
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60223904T Expired - Fee Related DE60223904T2 (de) | 2001-01-26 | 2002-01-22 | Benzylaminanalogen |
Country Status (11)
Country | Link |
---|---|
US (5) | US7504437B2 (de) |
EP (1) | EP1362844B1 (de) |
JP (2) | JP4176997B2 (de) |
AT (1) | ATE380172T1 (de) |
AU (1) | AU2002226687B9 (de) |
CA (1) | CA2435883A1 (de) |
DE (1) | DE60223904T2 (de) |
DK (1) | DK1362844T3 (de) |
ES (1) | ES2299561T3 (de) |
PT (1) | PT1362844E (de) |
WO (1) | WO2002059074A1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60144284D1 (de) | 2000-11-01 | 2011-05-05 | Millennium Pharm Inc | Stickstoffhaltige heterozyklische verbindungen und verfahren zu deren herstellung |
JP4676961B2 (ja) * | 2003-10-21 | 2011-04-27 | コルシド・ファーマシューティカルズ・インコーポレイテッド | コリンエステラーゼを阻害し、薬理活性物質を放出するカルバモイルエステル類 |
AT500143A1 (de) * | 2004-04-22 | 2005-11-15 | Sanochemia Pharmazeutika Ag | Cholinesterase-inhibitoren in liposomen sowie deren herstellung und verwendung |
TW200829171A (en) | 2006-11-17 | 2008-07-16 | Nihon Nohyaku Co Ltd | Haloalkyl sulfonanilide derivatives or salts thereof, herbicide using it as effective constituent and use-method thereof |
WO2008097546A2 (en) | 2007-02-02 | 2008-08-14 | Colucid Pharmaceuticals, Inc. | Compounds that inhibit cholinesterase |
AU2008223916A1 (en) * | 2007-03-05 | 2008-09-12 | F. Hoffmann-La Roche Ag | Aminoamides as orexin antagonists |
CN102762554A (zh) | 2010-02-16 | 2012-10-31 | 辉瑞大药厂 | 5-ht4受体的部分激动剂(r)-4-((4-((4-(四氢呋喃-3-基氧基)苯并[d]异*唑-3-基氧基)甲基)哌啶-1-基)甲基)四氢-2h-吡喃-4-醇 |
CN102850318A (zh) * | 2011-07-01 | 2013-01-02 | 中国人民解放军军事医学科学院毒物药物研究所 | 新的选择性5-羟色胺重摄取抑制剂及其医药用途 |
CN103131747A (zh) * | 2013-03-15 | 2013-06-05 | 康化(上海)新药研发有限公司 | 利用生物酶手性拆分合成(s)-3-(4-羟基苯基)-3-甲氨基丙酸的方法 |
CN107141266B (zh) * | 2017-06-28 | 2019-04-09 | 佳木斯大学附属第一医院 | 一种用于治疗阿尔茨海默病的杂环化合物及其制备方法 |
CN109225653B (zh) * | 2018-07-19 | 2020-11-06 | 昆明理工大学 | 一种高磷赤褐铁矿石除磷的选矿方法 |
JP7324930B2 (ja) | 2019-07-18 | 2023-08-10 | フアシアシェンシェン ファーマシューティカル ベイジン カンパニー リミテッド | カルバメート置換スチリルスルホン類化合物及びその製造方法ならびにその使用 |
CN114522707B (zh) * | 2022-02-22 | 2023-07-21 | 中南大学 | 一种碱土金属碳酸盐负载纳米钌复合材料及其制备方法和应用 |
CN115215769B (zh) * | 2022-06-28 | 2024-01-30 | 黄淮学院 | 一种用于检测乙酰胆碱酯酶的荧光探针及其制备方法与应用 |
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US3217007A (en) * | 1965-11-09 | Halo- and nitro-substituted phenethyl-z- methyl tetrahydroisoquinolsnes | ||
JPS4318547Y1 (de) | 1965-04-13 | 1968-07-31 | ||
US3557122A (en) * | 1968-10-10 | 1971-01-19 | Warner Lambert Pharmaceutical | 5,6,7a,8,11,11a,12,12a-octahydroindolo (2,1-a)isoquinolin-9(10h)-ones |
IL33480A (en) * | 1968-12-10 | 1973-03-30 | Tanabe Seiyaku Co | 6,7-diacyloxy-tetrahydro-isoquinolines and their preparation |
JPS4714108U (de) | 1971-03-17 | 1972-10-19 | ||
JPS5734275B2 (de) * | 1973-07-30 | 1982-07-22 | ||
JPS5246232B2 (de) * | 1973-07-31 | 1977-11-22 | ||
JPS5148677A (en) | 1974-10-22 | 1976-04-26 | Hokuriku Pharmaceutical | 00 ashiruhaigenaminno seizohoho |
JPS5247474B2 (de) | 1974-11-20 | 1977-12-02 | ||
JPS5170772A (ja) | 1974-11-27 | 1976-06-18 | Tanabe Seiyaku Co | Tetorahidoroisokinorinjudotaino seiho |
JPS5170774A (ja) | 1974-12-05 | 1976-06-18 | Tanabe Seiyaku Co | Tetorahidoroisokinorinjudotaino seiho |
JPS5186478A (en) | 1975-01-17 | 1976-07-29 | Fujisawa Pharmaceutical Co | 1*2*3*44 tetorahidoroisokinorinruio seizosuruhoho |
JPS52102281A (en) | 1976-02-24 | 1977-08-27 | Tanabe Seiyaku Co Ltd | Tetrahydroisoquinoline derivatives |
US4207343A (en) * | 1978-06-22 | 1980-06-10 | Eli Lilly And Company | 1-Phenyl-3-(substituted phenoxy)propylamines |
JPS57139066A (en) | 1981-02-20 | 1982-08-27 | Fujisawa Pharmaceut Co Ltd | Isoquinoline derivative and its preparation |
JPS62265266A (ja) * | 1986-05-13 | 1987-11-18 | Takasago Corp | N−アシル−テトラヒドロイソキノリン類の製造法 |
US5135947A (en) * | 1987-04-09 | 1992-08-04 | Eli Lilly And Company | 1-phenyl-3-naphthalenyloxypropanamines and their use as selective serotonin reuptake inhibitors |
US4920132A (en) | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
NO880840L (no) | 1988-02-26 | 1989-08-28 | Jan Saelensminde | Fremgangsmaate til behandling av betong. |
US5187168A (en) | 1991-10-24 | 1993-02-16 | American Home Products Corporation | Substituted quinazolines as angiotensin II antagonists |
GB9205505D0 (en) | 1992-03-13 | 1992-04-29 | Ici Plc | Cyclic compounds |
AU674358B2 (en) | 1992-10-28 | 1996-12-19 | Toyama Chemical Co. Ltd. | Novel 1,2-benzoisoxazole derivative or its salt and brain -protecting agent comprising the same |
NZ257955A (en) | 1992-12-02 | 1996-05-28 | Pfizer | Catechol diethers pharmaceutical compositions |
US5292962A (en) * | 1992-12-11 | 1994-03-08 | Eli Lilly And Company | Intermediates to 1-phenyl-3-naphthalenyloxy-propanamines |
US5589489A (en) | 1993-12-15 | 1996-12-31 | Zeneca Limited | Cyclic amide derivatives for treating asthma |
JPH0841008A (ja) | 1994-07-29 | 1996-02-13 | Ono Pharmaceut Co Ltd | 一酸化窒素合成酵素阻害剤 |
US6743902B1 (en) * | 1994-11-02 | 2004-06-01 | Valeant Pharmaceuticals International | Sugar modified nucleosides |
US5681940A (en) | 1994-11-02 | 1997-10-28 | Icn Pharmaceuticals | Sugar modified nucleosides and oligonucleotides |
WO1996022276A1 (fr) * | 1995-01-20 | 1996-07-25 | Nippon Shinyaku Co., Ltd. | Derives d'ethylamine et medicaments |
IL117149A0 (en) | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
GB9508748D0 (en) | 1995-04-28 | 1995-06-14 | British Biotech Pharm | Benzimidazole derivatives |
DE19643048A1 (de) * | 1996-10-18 | 1998-04-23 | Daimler Benz Ag | Verbindungen und deren Verwendung sowie Verfahren zur Herstellung von flüssigkristallinen Polymeren daraus |
DE19651099A1 (de) | 1996-12-09 | 1998-06-10 | Consortium Elektrochem Ind | Mehrkomponentensystem zum Verändern, Abbau oder Bleichen von Lignin, ligninhaltigen Materialien oder ähnlichen Stoffen sowie Verfahren zu seiner Anwendung |
WO1998027972A2 (en) | 1996-12-23 | 1998-07-02 | Texas A & M University | Anti-amyloidogenic agents |
JP2001521027A (ja) | 1997-10-27 | 2001-11-06 | アイエスケー・アメリカズ・インコーポレーティッド | 置換ベンゼン化合物、それらの製造方法並びにそれらを含有する除草剤組成物及び落葉剤組成物 |
RU2293728C2 (ru) | 1999-11-03 | 2007-02-20 | Эймр Текнолоджи, Инк. | Производные тетрагидроизохинолина, содержащая их фармацевтическая композиция, способ ингибирования синаптического захвата допамина и способ лечения |
TWI284639B (en) | 2000-01-24 | 2007-08-01 | Shionogi & Co | A compound having thrombopoietin receptor agonistic effect |
AU2002341034B2 (en) | 2001-03-21 | 2007-06-14 | Molteni Therapeutics S.R.L. | Metal substituted non centrosimmetrical phthalocyanine analogues, their preparation and use in photodynamic therapy and in vivo diagnostic |
DE10211597A1 (de) * | 2002-03-15 | 2003-10-02 | Merck Patent Gmbh | Verfahren zur Herstellung von Ringverbindungen |
-
2002
- 2002-01-22 AT AT02716323T patent/ATE380172T1/de not_active IP Right Cessation
- 2002-01-22 PT PT02716323T patent/PT1362844E/pt unknown
- 2002-01-22 CA CA002435883A patent/CA2435883A1/en not_active Abandoned
- 2002-01-22 DE DE60223904T patent/DE60223904T2/de not_active Expired - Fee Related
- 2002-01-22 AU AU2002226687A patent/AU2002226687B9/en not_active Ceased
- 2002-01-22 ES ES02716323T patent/ES2299561T3/es not_active Expired - Lifetime
- 2002-01-22 EP EP02716323A patent/EP1362844B1/de not_active Expired - Lifetime
- 2002-01-22 WO PCT/JP2002/000400 patent/WO2002059074A1/ja active IP Right Grant
- 2002-01-22 DK DK02716323T patent/DK1362844T3/da active
- 2002-01-24 JP JP2002015136A patent/JP4176997B2/ja not_active Expired - Fee Related
-
2003
- 2003-07-23 JP JP2003200434A patent/JP2004107322A/ja not_active Withdrawn
- 2003-07-28 US US10/629,108 patent/US7504437B2/en not_active Expired - Fee Related
-
2006
- 2006-10-19 US US11/583,404 patent/US7504393B2/en not_active Expired - Fee Related
- 2006-10-19 US US11/583,499 patent/US7514475B2/en not_active Expired - Fee Related
-
2007
- 2007-06-18 US US11/820,218 patent/US20080255095A1/en not_active Abandoned
-
2009
- 2009-01-29 US US12/322,173 patent/US20090149444A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2002226687B2 (en) | 2005-08-25 |
US7504393B2 (en) | 2009-03-17 |
EP1362844B1 (de) | 2007-12-05 |
CA2435883A1 (en) | 2002-08-01 |
AU2002226687B9 (en) | 2005-10-20 |
US20090149444A1 (en) | 2009-06-11 |
US7504437B2 (en) | 2009-03-17 |
US20080255095A1 (en) | 2008-10-16 |
PT1362844E (pt) | 2008-03-10 |
DK1362844T3 (da) | 2008-04-14 |
JP2003176256A (ja) | 2003-06-24 |
EP1362844A1 (de) | 2003-11-19 |
US7514475B2 (en) | 2009-04-07 |
ATE380172T1 (de) | 2007-12-15 |
US20040067981A1 (en) | 2004-04-08 |
WO2002059074A1 (fr) | 2002-08-01 |
EP1362844A4 (de) | 2004-05-26 |
DE60223904T2 (de) | 2008-11-27 |
JP4176997B2 (ja) | 2008-11-05 |
US20070037793A1 (en) | 2007-02-15 |
US20070037795A1 (en) | 2007-02-15 |
JP2004107322A (ja) | 2004-04-08 |
ES2299561T3 (es) | 2008-06-01 |
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