PT1362844E - Análogo da benzilamina - Google Patents
Análogo da benzilamina Download PDFInfo
- Publication number
- PT1362844E PT1362844E PT02716323T PT02716323T PT1362844E PT 1362844 E PT1362844 E PT 1362844E PT 02716323 T PT02716323 T PT 02716323T PT 02716323 T PT02716323 T PT 02716323T PT 1362844 E PT1362844 E PT 1362844E
- Authority
- PT
- Portugal
- Prior art keywords
- benzylamine
- analogue
- represent
- different
- same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C07C219/30—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
- C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/44—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/20—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C333/02—Monothiocarbamic acids; Derivatives thereof
- C07C333/04—Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/68—One oxygen atom attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Quinoline Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001018386 | 2001-01-26 | ||
JP2001305182 | 2001-10-01 | ||
PCT/JP2002/000400 WO2002059074A1 (fr) | 2001-01-26 | 2002-01-22 | Analogue de benzylamine |
JP2002015136A JP4176997B2 (ja) | 2001-01-26 | 2002-01-24 | ヒドロキシベンジルアミン誘導体 |
TW91101231 | 2002-01-25 | ||
JP2002214641 | 2002-07-24 | ||
JP2003200434A JP2004107322A (ja) | 2001-01-26 | 2003-07-23 | ヒドロキシベンジルアミン誘導体を含有する医薬 |
US10/629,108 US7504437B2 (en) | 2001-01-26 | 2003-07-28 | Benzylamine analogues |
US11/583,499 US7514475B2 (en) | 2001-01-26 | 2006-10-19 | Benzylamine analogues |
US11/820,218 US20080255095A1 (en) | 2001-01-26 | 2007-06-18 | Benzylamine analogues |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1362844E true PT1362844E (pt) | 2008-03-10 |
Family
ID=32300480
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT02716323T PT1362844E (pt) | 2001-01-26 | 2002-01-22 | Análogo da benzilamina |
Country Status (11)
Country | Link |
---|---|
US (5) | US7504437B2 (de) |
EP (1) | EP1362844B1 (de) |
JP (2) | JP4176997B2 (de) |
AT (1) | ATE380172T1 (de) |
AU (1) | AU2002226687B9 (de) |
CA (1) | CA2435883A1 (de) |
DE (1) | DE60223904T2 (de) |
DK (1) | DK1362844T3 (de) |
ES (1) | ES2299561T3 (de) |
PT (1) | PT1362844E (de) |
WO (1) | WO2002059074A1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE502928T1 (de) | 2000-11-01 | 2011-04-15 | Millennium Pharm Inc | Stickstoffhaltige heterozyklische verbindungen und verfahren zu deren herstellung |
CN1898201A (zh) | 2003-10-21 | 2007-01-17 | 森蒂有限公司 | 可抑制胆碱酯酶和释放药理学活性试剂的氨基甲酸酯 |
AT500143A1 (de) * | 2004-04-22 | 2005-11-15 | Sanochemia Pharmazeutika Ag | Cholinesterase-inhibitoren in liposomen sowie deren herstellung und verwendung |
TW200829171A (en) | 2006-11-17 | 2008-07-16 | Nihon Nohyaku Co Ltd | Haloalkyl sulfonanilide derivatives or salts thereof, herbicide using it as effective constituent and use-method thereof |
JP2010518010A (ja) | 2007-02-02 | 2010-05-27 | コルシド・ファーマシューティカルズ・インコーポレイテッド | コリンエステラーゼを阻害する化合物 |
MX2009009121A (es) * | 2007-03-05 | 2009-09-03 | Hoffmann La Roche | Aminoamidas como antagonistas de orexina. |
MX2012008721A (es) | 2010-02-16 | 2012-08-17 | Pfizer | (r)-4-((4-((4-(tetrahidrofuran-3-iloxi)benzo[d]isoxazol-3-iloxi)m etil) tetrahidro-2h-piran-4-ol, un agonista pacial de receptores 5-ht4. |
CN102850318A (zh) * | 2011-07-01 | 2013-01-02 | 中国人民解放军军事医学科学院毒物药物研究所 | 新的选择性5-羟色胺重摄取抑制剂及其医药用途 |
CN103131747A (zh) * | 2013-03-15 | 2013-06-05 | 康化(上海)新药研发有限公司 | 利用生物酶手性拆分合成(s)-3-(4-羟基苯基)-3-甲氨基丙酸的方法 |
CN107141266B (zh) * | 2017-06-28 | 2019-04-09 | 佳木斯大学附属第一医院 | 一种用于治疗阿尔茨海默病的杂环化合物及其制备方法 |
CN109225653B (zh) * | 2018-07-19 | 2020-11-06 | 昆明理工大学 | 一种高磷赤褐铁矿石除磷的选矿方法 |
EP4001263B1 (de) * | 2019-07-18 | 2024-03-27 | Huaxiashengsheng Pharmaceutical Beijing Co., Ltd. | Carbamatsubstituierte styrylsulfonverbindung, verfahren zu ihrer herstellung und ihre verwendung |
CN114522707B (zh) * | 2022-02-22 | 2023-07-21 | 中南大学 | 一种碱土金属碳酸盐负载纳米钌复合材料及其制备方法和应用 |
CN115215769B (zh) * | 2022-06-28 | 2024-01-30 | 黄淮学院 | 一种用于检测乙酰胆碱酯酶的荧光探针及其制备方法与应用 |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3217007A (en) * | 1965-11-09 | Halo- and nitro-substituted phenethyl-z- methyl tetrahydroisoquinolsnes | ||
JPS4318547Y1 (de) | 1965-04-13 | 1968-07-31 | ||
US3557122A (en) * | 1968-10-10 | 1971-01-19 | Warner Lambert Pharmaceutical | 5,6,7a,8,11,11a,12,12a-octahydroindolo (2,1-a)isoquinolin-9(10h)-ones |
IL33480A (en) * | 1968-12-10 | 1973-03-30 | Tanabe Seiyaku Co | 6,7-diacyloxy-tetrahydro-isoquinolines and their preparation |
JPS4714108U (de) | 1971-03-17 | 1972-10-19 | ||
JPS5734275B2 (de) * | 1973-07-30 | 1982-07-22 | ||
JPS5246232B2 (de) * | 1973-07-31 | 1977-11-22 | ||
JPS5148677A (en) | 1974-10-22 | 1976-04-26 | Hokuriku Pharmaceutical | 00 ashiruhaigenaminno seizohoho |
JPS5247474B2 (de) | 1974-11-20 | 1977-12-02 | ||
JPS5170772A (ja) | 1974-11-27 | 1976-06-18 | Tanabe Seiyaku Co | Tetorahidoroisokinorinjudotaino seiho |
JPS5170774A (ja) | 1974-12-05 | 1976-06-18 | Tanabe Seiyaku Co | Tetorahidoroisokinorinjudotaino seiho |
JPS5186478A (en) | 1975-01-17 | 1976-07-29 | Fujisawa Pharmaceutical Co | 1*2*3*44 tetorahidoroisokinorinruio seizosuruhoho |
JPS52102281A (en) | 1976-02-24 | 1977-08-27 | Tanabe Seiyaku Co Ltd | Tetrahydroisoquinoline derivatives |
US4207343A (en) * | 1978-06-22 | 1980-06-10 | Eli Lilly And Company | 1-Phenyl-3-(substituted phenoxy)propylamines |
JPS57139066A (en) | 1981-02-20 | 1982-08-27 | Fujisawa Pharmaceut Co Ltd | Isoquinoline derivative and its preparation |
JPS62265266A (ja) * | 1986-05-13 | 1987-11-18 | Takasago Corp | N−アシル−テトラヒドロイソキノリン類の製造法 |
US5135947A (en) * | 1987-04-09 | 1992-08-04 | Eli Lilly And Company | 1-phenyl-3-naphthalenyloxypropanamines and their use as selective serotonin reuptake inhibitors |
US4920132A (en) | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
NO880840L (no) | 1988-02-26 | 1989-08-28 | Jan Saelensminde | Fremgangsmaate til behandling av betong. |
US5187168A (en) | 1991-10-24 | 1993-02-16 | American Home Products Corporation | Substituted quinazolines as angiotensin II antagonists |
GB9205505D0 (en) | 1992-03-13 | 1992-04-29 | Ici Plc | Cyclic compounds |
JP3457669B2 (ja) | 1992-10-28 | 2003-10-20 | 富山化学工業株式会社 | 新規な1,2−ベンゾイソオキサゾール誘導体またはその塩,それらからなる脳保護剤 |
NZ257955A (en) | 1992-12-02 | 1996-05-28 | Pfizer | Catechol diethers pharmaceutical compositions |
US5292962A (en) * | 1992-12-11 | 1994-03-08 | Eli Lilly And Company | Intermediates to 1-phenyl-3-naphthalenyloxy-propanamines |
US5589489A (en) | 1993-12-15 | 1996-12-31 | Zeneca Limited | Cyclic amide derivatives for treating asthma |
JPH0841008A (ja) | 1994-07-29 | 1996-02-13 | Ono Pharmaceut Co Ltd | 一酸化窒素合成酵素阻害剤 |
US5681940A (en) * | 1994-11-02 | 1997-10-28 | Icn Pharmaceuticals | Sugar modified nucleosides and oligonucleotides |
US6743902B1 (en) * | 1994-11-02 | 2004-06-01 | Valeant Pharmaceuticals International | Sugar modified nucleosides |
AU4458996A (en) * | 1995-01-20 | 1996-08-07 | Nippon Shinyaku Co. Ltd. | Ethylamine derivatives and drugs |
IL117149A0 (en) | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
GB9508748D0 (en) | 1995-04-28 | 1995-06-14 | British Biotech Pharm | Benzimidazole derivatives |
DE19643048A1 (de) * | 1996-10-18 | 1998-04-23 | Daimler Benz Ag | Verbindungen und deren Verwendung sowie Verfahren zur Herstellung von flüssigkristallinen Polymeren daraus |
DE19651099A1 (de) | 1996-12-09 | 1998-06-10 | Consortium Elektrochem Ind | Mehrkomponentensystem zum Verändern, Abbau oder Bleichen von Lignin, ligninhaltigen Materialien oder ähnlichen Stoffen sowie Verfahren zu seiner Anwendung |
AU5727798A (en) | 1996-12-23 | 1998-07-17 | Texas A & M University, The | Anti-amyloidogenic agents |
WO1999021837A1 (en) * | 1997-10-27 | 1999-05-06 | Isk Americas Incorporated | Substituted benzene compounds, process for their preparation, and herbicidal and defoliant compositions containing them |
NZ519146A (en) | 1999-11-03 | 2004-02-27 | Albany Molecular Res Inc | 4-phenyl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin |
TWI284639B (en) | 2000-01-24 | 2007-08-01 | Shionogi & Co | A compound having thrombopoietin receptor agonistic effect |
ATE298341T1 (de) | 2001-03-21 | 2005-07-15 | Molteni & C | Metallsubstituierte, nicht zentrosymmetrische phthalocyanin-analoga, deren herstellung und verwendung zur photodynamischen therapie, und als in-vivo-diagnostikum |
DE10211597A1 (de) * | 2002-03-15 | 2003-10-02 | Merck Patent Gmbh | Verfahren zur Herstellung von Ringverbindungen |
-
2002
- 2002-01-22 AU AU2002226687A patent/AU2002226687B9/en not_active Ceased
- 2002-01-22 DK DK02716323T patent/DK1362844T3/da active
- 2002-01-22 EP EP02716323A patent/EP1362844B1/de not_active Expired - Lifetime
- 2002-01-22 CA CA002435883A patent/CA2435883A1/en not_active Abandoned
- 2002-01-22 ES ES02716323T patent/ES2299561T3/es not_active Expired - Lifetime
- 2002-01-22 PT PT02716323T patent/PT1362844E/pt unknown
- 2002-01-22 AT AT02716323T patent/ATE380172T1/de not_active IP Right Cessation
- 2002-01-22 DE DE60223904T patent/DE60223904T2/de not_active Expired - Fee Related
- 2002-01-22 WO PCT/JP2002/000400 patent/WO2002059074A1/ja active IP Right Grant
- 2002-01-24 JP JP2002015136A patent/JP4176997B2/ja not_active Expired - Fee Related
-
2003
- 2003-07-23 JP JP2003200434A patent/JP2004107322A/ja not_active Withdrawn
- 2003-07-28 US US10/629,108 patent/US7504437B2/en not_active Expired - Fee Related
-
2006
- 2006-10-19 US US11/583,499 patent/US7514475B2/en not_active Expired - Fee Related
- 2006-10-19 US US11/583,404 patent/US7504393B2/en not_active Expired - Fee Related
-
2007
- 2007-06-18 US US11/820,218 patent/US20080255095A1/en not_active Abandoned
-
2009
- 2009-01-29 US US12/322,173 patent/US20090149444A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US7514475B2 (en) | 2009-04-07 |
DK1362844T3 (da) | 2008-04-14 |
WO2002059074A1 (fr) | 2002-08-01 |
DE60223904D1 (de) | 2008-01-17 |
US20070037793A1 (en) | 2007-02-15 |
CA2435883A1 (en) | 2002-08-01 |
US20040067981A1 (en) | 2004-04-08 |
AU2002226687B2 (en) | 2005-08-25 |
US7504393B2 (en) | 2009-03-17 |
EP1362844B1 (de) | 2007-12-05 |
ATE380172T1 (de) | 2007-12-15 |
JP4176997B2 (ja) | 2008-11-05 |
US7504437B2 (en) | 2009-03-17 |
DE60223904T2 (de) | 2008-11-27 |
EP1362844A4 (de) | 2004-05-26 |
US20080255095A1 (en) | 2008-10-16 |
US20090149444A1 (en) | 2009-06-11 |
AU2002226687B9 (en) | 2005-10-20 |
ES2299561T3 (es) | 2008-06-01 |
US20070037795A1 (en) | 2007-02-15 |
JP2003176256A (ja) | 2003-06-24 |
JP2004107322A (ja) | 2004-04-08 |
EP1362844A1 (de) | 2003-11-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL160304A0 (en) | ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR delta | |
PT976748E (pt) | Derivados de pirrolidina com actividade inibidora de fosfolipase a2 | |
AU1497997A (en) | Use of estrogen antagonists and estrogen agonists in inhibiting pathological conditions | |
EP1217001A4 (de) | Chinuclidin-verbindungen und medikamente die diese als aktive wirkstoffe enthalten | |
PT1362844E (pt) | Análogo da benzilamina | |
IL150650A0 (en) | Piperidine derivatives and pharmaceutical compositions containing the same | |
AU4523797A (en) | Atherosclerosis treatment | |
EP1184388A4 (de) | Sulphostinanaloga und verfahren zur herstellung von sulphostin und analoga davon | |
PT916651E (pt) | DERIVADOS DE áCIDO FENILALQUILCARBOXILICO | |
EP0807627A3 (de) | Anilide als ACAT-Hemmer | |
HU9503090D0 (en) | Novel bisoxadiazolidine derivative | |
EP1074556A4 (de) | Phosphonsäure-diester-derivate | |
DK1433480T3 (da) | Lægemiddel indeholdende pyrimidin-derivat |